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Lysergamides When it comes to therapeutic potential, LSD and DMT are incomparable to anything else

Axemancometh

Bluelighter
Joined
Mar 12, 2026
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65
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Canada
This is a recent thought that came to me during my last acid trip - and one that out of all my drug-fuelled opinions on this earth, this is something I deeply with all my heart believe in.

I have been living with Obsessive-Compulsive disorder my entire life. Because of this, it has also extended itself into a general social anxiety with atypical depression. I have gone the entirety of my youth dealing with this sort of condition; on my own; with nobody - not even my own family - to help me. I have also been a recreational drug user for over five years up to this point - A habit I picked up in high school when I stopped caring about myself and my relation to this planet. I have smoked my fair share of pot; I have eaten my share of molly rock, I have done an uncountable amount of ketamine; I have sniffed and eaten Shulgin's favourite (2C-B); I have even went to the far margins of the internet to procure myself synthetic lab-created mescaline - all to either get high or explore myself and yaddah.

To this date, there have been no other compounds with which I have had my life and perceptions about reality so profoundly impacted as with LSD-25 and DMT. (this includes all types of psilocybin-containing mushrooms, as psilocin's true designation is 4-HO-DMT) These two compounds have so forced me to look at my life from the outside to see the psychological wreck of a human being I am. Under their influence, they have transformed my reserved demeanour into being emotionally open and honest with friends (and sometimes even complete strangers) as well as myself.

It was my first really bad acid trip, whereupon I also experienced ego-dissolution for the first time, that I began making a real effort to live in the present moment - and not ruminate on my obsessive thoughts which would snowball into self doubt.

I noticed very early on that the 'afterglow' effect from these two compounds almost completely eradicated my obsessive thinking, and my intrusive thoughts either ceased or were completely ignored; I felt 'normal' for the first time as long as I could remember. I felt free. I felt alive.

It was only with the lessons that I was taught on these psychedelics that I was able to climb out of the absolute hole I used to inhabit into a new whole. I still have a ways away to go for my mental health, to be honest, but I would be nowhere I am now without their assistance. Under their influence I learn to gain the self respecting confident image I need. It actually helps with my speech impediment by loosening up my tongue, and slowing my words down into comprehensible phrases that flow freely.

Other than perhaps marijuana, LSD and DMT have been also the most effective in keeping me away from harder drugs, in keeping my attitude straight, and a proper lid on my own hypomanic ramblings that I will often subject my peers to.

I have hung around my share of hippies and freaks; stoner witches and drug addicted schizophrenics; ravers and the every other drug user. Nobody that I've talked to has ever discussed the positive effects of these drugs for anything other than getting high - this is something that I find disappointing. LSD and DMT are so much more than just 'drugs' in the traditional sense. Yes they absolutely do make you feel good at times, and the visuals are nice no matter what; but they have so much more potential that the reputation they receive as recreational (or in the words of a random nurse I had the pleasure of speaking with - street drugs) is detrimental to possible exploration of their qualities as therapeutic agents for people like me.

I had been recently speaking to a doctor about my mental health problems (exacerbated by my spiraling substance abuse issue) when I was 'put on' SSRI medication. (industry standard in treating OCD and depression) I found that the results I was getting from these (10 mg Escitalopram, later 25 mg sertraline) were lacklustre at best, and dangerously aggravating at worst. I would have that same 'normal' feeling as with the psychedelic afterglow for about six hours, whereupon my symptoms always got worse until my next dose. Doctors and councillors have completely dismissed my attempts to explain the benefit these substances were bringing into my life as delusions - I was simply a depressed young man with a drug problem.

I need these substances in my life to some degree in order to stay grounded. They help me more than anything else can in terms of keeping me sane. These drugs are medicine - they ought to be prescribed in small amounts to microdose, and guided therapy sessions ought to be held with them at a nucleus. When governments across the world are penalizing the possession and distribution of these chemicals, they are preventing the people who require proper help from getting it. Allowing legal access to these means one less mentally ill freak loses years of their life to a psychological prison; it is one less person who blows their head off in public, shoots up an office, or plunges their car into a lake. I know for sure that If I had been given proper guided psychedelic therapy that I would be much better off than having to do it myself by experimenting with all sorts of doses and potentially damaging my psyche/body any further.

Albert Hofmann once mentioned how he was frustrated at both the young hippy generation for abusing his creation, (he himself mentioned the expressed the potential danger such high and unsupervised dosages could induce) as well as the governments of the world for banning it and persecuting those who used it. He saw the potential spiritual benefits it had and knew that it was something to be handled responsibly.

Psychedelic substances should never be illegal. They are a beacon of light for people who have nothing else to turn to for their psychological struggles. To penalise somebody for possessing or ingesting them is immoral, and unethical. Psychedlics are not drugs. They may get you high, but so does Xanax, and zolpiclone, and gabapentin - they are rather medicine; and whether you like to admit it or not, you know the reason why you keep taking them is you chase the feeling of being whole of body and mind - something that nothing else on this earth except for meditation can really do.

I'm not knocking on anybody who likes to drop out and trip balls - I do the exact same thing. But the sooner that society realises these things for what they truly are, the sooner that we can all be happier and healthier in our lives.
 
@Axemancometh
so how frequently and at what dosage are you doing each of lsd and dmt?
I won't even lie to you I've been picking up the pace on psychedelics. Recently it's been about once every three weeks but it used to be only a few times a year. (I plan on returning to my original regimen soon)

As for the dosing, it varies. normally it's between 60 and 150ugs of LSD, and 30-50mg smoked DMT. Psilocybin goes to around 2-4 grams of dried fungi each sesh. (I'm not doing all of these at once) Despite what I said it ought to be like, I almost never microdose myself; like I said - I have thing for getting high.

What I do now is not ideal by any means, but it works in its own insane way for me. Having these things in my life helps me out a ton and more 'outside' people ought to be tuned in
 
makes sense to me!!
I do smaller doses but more often.
they are both excellent drugs. one is very fast, and the other very wide - to suit the hour or the day.
 
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