Lybalvi - another anti depressant that causes opioid precip withdrawl

[notsmokeymcpot42088]

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I dont really have much else to answer seeing as while we disagree on opiates we do agree that big pharma should not be forcing opiate antagonists onto consumers.

That is the major concern absolutely.

Again I thank you for participating

 

[JackARoe]

I have to read through the thread. But I too have looked at these commercials with suspicious eyes. Two shit drugs mixed. I just remember Cosmic Charley coming off olanzapine and how hard it was. Took copious amount of other drugs to cope and then passed away. It is pretty much documented in the PD social thread. Olanzapine is a shit drug.

Yes they (some people) feel they want to heard the masses and turn them into zombies. Psychedelics are the antidote to that but it looks like if you take olanzapine you can't trip. Can't trip and can't take opiates. Nice drug.

Ok I usually read every post before commenting, going back to see how close I am to the topic.

 

[SotPoker1012]

It does seem very peculiar to me that they'd opt for an opioid antagonist to counteract weight gain from an antipsychotic. Opioid antagonists certainly don't come to mind as a weight loss drug.

Isn't it a bit irresponsible? What happens if someone taking this sustains a serious injury? This seems like it could pose a lot of problems for emergency medicine. In an emergency, a patient might not think or might not be able to communicate that they take this drug.

 

[notsmokeymcpot42088]

It does seem very peculiar to me that they'd opt for an opioid antagonist to counteract weight gain from an antipsychotic. Opioid antagonists certainly don't come to mind as a weight loss drug.

Isn't it a bit irresponsible? What happens if someone taking this sustains a serious injury? This seems like it could pose a lot of problems for emergency medicine. In an emergency, a patient might not think or might not be able to communicate that they take this drug.

You have a great point about someone getting injured and I didnt even think of that

Seems downright spiteful if the person isn't particularly asking for a weight loss drug to counter act this 'common side effect' -- we are sympatico with it being a very odd choice for a weight loss drug to compound as well.
Pushed on a seemingly captive market --- Suspicious indeed!

You are also cognitively impaired so the chance of having an accident goes up a bit.
Something I haven't addressed till now is I am guessing you are alot more likely to use opiates/self medicate as well. (That is speculatory at this juncture. I feel like most opiate users I know had some kind of ssri script)

If they got that 17% of people I do wonder what percentage of "Opiate users" that would take out of play.

No opiates and no tripping --- I quit takin my celexa as the possibility getting a trip outweighs (any) benefit of that ish. I would be on the suboxone injection but the slight possibility of PWD is too much risk.

I dont think there are words to describe how horrible a situation that is other than the explanation of --- You are cramming 72 hours to a couple weeks worth of withdrawal (already something ya gtta know to put words to) into a COUPLE HOURS YOU EXPERIENCE ALL OF IT AT ONCE.

 

[notsmokeymcpot42088]

I worried about the seeming increase in prescribed naltrexone to treat opiate misuse disorder. The reason being that dysphoria is a common side effect. If it blockades the reward pathways, a person cannot experience happiness. Thus, when combined with post-AWS depression, it could pose a risk of a patient self-harming (or worse).

That makes all of the sense and I am not quite sure why I never put it together -- does this possibly explain a lack of emotional highs (Probaly lows as well) and a bit of generalized depression in somebody (Wonder who) on subs long term?

Thank you for puttin the info out there to learn from

 

[N0ph0n0]

Isn't it a bit irresponsible? What happens if someone taking this sustains a serious injury? This seems like it could pose a lot of problems for emergency medicine. In an emergency, a patient might not think or might not be able to communicate that they take this drug.

They can put them into a k-hole or give them a synthethic cannibanoid like Dronabinol or Nabilone. Opioids should not be used as pain killers, even the US military is replacing morphine injectors with ketamine injectors in their soldier's medkits.

 

[notsmokeymcpot42088]

Ketamine or synthetic cannaniboids instead of morphine --- that is simply cruel and unusual IME.- I dont think the US military is anywhere near the gold standard of "How a human should be treated" either.

 

[emkee_reinvented]

Is Samidorphan btw like Naltrexone [assumed they put in the last one] but as 4QDSAR mentioned "sort of assumed it would be some what like it" is it like it ?
And why is Olanzapine named a AD not that i can t be used as maybe. But technically it s a AP and an anti-Antihistamine correct.

Just checked so they still prescribe Codeine with APAP here, so there are stil useless formules prescribed. Any idea why they would wanna compound it like this the Lybalvi ? Is there a second motive beyond preventing or causing precipitated WD sor preventing drug abuse or getting pleasure off anything. Do these compound s dull live ?

 

[notsmokeymcpot42088]

I am actually not personally familiar with samidorphan --- kinda sounds like a DXM byproduct with no purpose or something but I have no idea and yea ... let @4DQSAR weigh in there. (if he/she wants of course, not puttin ya on blast!)

Haha I am going to double down on my semi ignorance here; I have never taken olanzapine either but it is an anti-psychotic and those have a sketchy past and present in the US. (anti-histamine is news to me but I can believe it)

YES THEY DULL LIFE (One could argue that is kind of the point) -- I mostly see them used on "Problematic" patients as a way to 'keep them in line' (For lack of a better term). A highly ethically questionable practice to begin with.
(That said I am pretty sure they do work for ppl with schizophrenia and there are not many options -- I guess, I dont wanna think about that lol)

Well they claim the FIRST motive is 'weight loss' but based on how little they care about our obesity -- and the worse side effects mentioned; as well as 'better' options......That feels like a LONG STRETCH to me.

Yea I remember when the FDA announced they were gunna stop compounding tylenol and I rejoiced ....than it never fcking happened and by than I wasnt taking em anymore so I just kinda shrugged and said "Thats the gov alright"....

For every lybalvi there is a spovado -- Esketamine nasal spray advertised with the tag line "If you have been on over two anti depressants you qualify to ask about sprovado"