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Kratom Kratom Megathread V.2

I noticed on the original post and quite rightly so to warn of the risks of mixing kratom with alcohol ,all drugs,medication etc should not be consumed with alcohol for obvious reasons but kratom does seem to have a synergy with sensible amounts of alcohol alot more than the usual suspects
do you mean an extract or plain leaf? Cause if its plain leaf it could be explained by the alcohol pulling additional mit out of the powder that otherwise would be destroyed by your liver. Of course alcohol is psychoactive on its own, just a suggestion of a possibility why it may add to the effects of kratom moreso than other opioids.
 
do you mean an extract or plain leaf? Cause if its plain leaf it could be explained by the alcohol pulling additional mit out of the powder that otherwise would be destroyed by your liver. Of course alcohol is psychoactive on its own, just a suggestion of a possibility why it may add to the effects of kratom moreso than other opioids.
No plain leaf ,never touch extracts
I just find it's a perfect compliment especially with low tolerance
 
I've been fortunate to have fresh leaves within 30 seconds of being picked from tree and was given an instant coffee and its prob the best coffee I've ever had .Great mix
 
No plain leaf ,never touch extracts
I just find it's a perfect compliment especially with low tolerance
Interesting. That would make sense with my theory but not confirm it. Could also be body chemistry (maybe your personal liver enzymes? All just theories still) or other factors.
It would narrow it down more (support my original hypothesis) if you didnt experience such a drastic addition of effects from an extract mixed with alcohol, though I absolutely am not recommending that since youre not already into extracts, just a thought
🤔
 
Interesting. That would make sense with my theory but not confirm it. Could also be body chemistry (maybe your personal liver enzymes? All just theories still) or other factors.
It would narrow it down more (support my original hypothesis) if you didnt experience such a drastic addition of effects from an extract mixed with alcohol, though I absolutely am not recommending that since youre not already into extracts, just a thought
🤔
No I won't be trying extract any time soon ,from what I've heard it's a devil.
I also experiance almost identical effects from dihydrocodeine as I do from kratom and can interchange without any withdrawl,I find it also mixes well with alcohol (not advisable)
Codeine on the other hand doesn't go well atol and can make me nauseous
I think it's the energetic effect of dhc at lower doses that mimics kratom ,for me any way
 
No I won't be trying extract any time soon ,from what I've heard it's a devil.
I also experiance almost identical effects from dihydrocodeine as I do from kratom and can interchange without any withdrawl,I find it also mixes well with alcohol (not advisable)
Codeine on the other hand doesn't go well atol and can make me nauseous
I think it's the energetic effect of dhc at lower doses that mimics kratom ,for me any way
Yeah, extract is a slippery slope if you arent careful.
Your preference doesnt honestly make sense to me. Ive always had personal beef with stimulating opioids (kratom, and oxy when not in pain excluded). They always make me mad as fuck when im on them for pain, but thats a combination of the baby doses they give me and the paradoxical stimulation that just makes me want to break shit, but hey, different strokes for different folks.

Ive never had DHC so I could like that, not really sure, and to clarify, I do enjoy basically all opioids, just the stimulating ones have a tendency to be VERY hit or miss for me.
Good to hear your experience with it though, jealous of your access to (im guessing OTC) DHC and codeine, hell, I'd buy pholcodin if it were available here 😆
 
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Yeah, extract is a slippery slope if you arent careful.
Your preference doesnt honestly make sense to me. Ive always had personal beef with stimulating opioids (kratom, and oxy when not in pain excluded). They always make me mad as fuck when im on them for pain, but thats a combomation of the baby doses they give me and the paradoxical stimulation that just makes me want to break shit, but hey, different strokes for different folks.

Ive never had DHC so I could like that, not really sure, and to clarify, I do enjoy basically all opioids, just the stimulating ones have a tendency to be VERY hit or miss for me.
Good to hear your experience with it though, jealous of your access to (im guessing OTC) DHC and codeine, hell, I'd buy pholcodin if it were available here 😆
Yeh I need it to be stimulating for my morning dose just to wake me up and lift my mood
I've tried red strains but can honestly say I barely feel any affects
I gave up otc as its such a faf but I've been lucky( or unlucky) to be prescribed dhc a number of times and its always 100x 30mg .
Course I don't always use the conventional route of administration
I'm certain you would like dhc it's a real mood lifter
 
Yeh I need it to be stimulating for my morning dose just to wake me up and lift my mood
I've tried red strains but can honestly say I barely feel any affects
I gave up otc as its such a faf but I've been lucky( or unlucky) to be prescribed dhc a number of times and its always 100x 30mg .
Course I don't always use the conventional route of administration
I'm certain you would like dhc it's a real mood lifter
Damn, its a travesty that you dont feel the red strains, again though I guess it illustrates differences in body chemistry
But DHC sounds actually wonderful 👌😊
 
Damn, its a travesty that you dont feel the red strains, again though I guess it illustrates differences in body chemistry
But DHC sounds actually wonderful 👌😊
I still feel it and it keeps wd away .
If I make strong tea with a white strain it has the opposite effect and I slouch in my chair content .
Tolerance is just the major problem
Kratom with zero Tolerance is bliss ,I've never had strong opioids
 
I still feel it and it keeps wd away .
If I make strong tea with a white strain it has the opposite effect and I slouch in my chair content .
Tolerance is just the major problem
Kratom with zero Tolerance is bliss ,I've never had strong opioids
Thats the strat man. Keep your bar low, cause when it gets higher, its hard to enjoy anything other than complete oblivion (personal observation of my own habits)
 
Went looking into some alternative reactions that can yield 7-OH-- id like your opinion on this one
I'd be cautious with this as it's not a validated or peer-reviewed method for producing 7-OH-mitragynine. Kitchen chemistry oxidations often generate complex byproducts that aren’t characterized, and the safety claims are shaky. Singlet oxygen handling, prolonged oxygen bubbling, and hot-plate drying can all create additional unknown oxidation products. Quercetin and citric acid don't guarantee safety and cannot retroactively make the reaction selective.

From the technical perspective, singlet oxygen reactions on complex alkaloids rarely give one clean product. You typically get a mixture of over-oxidized and rearranged compounds. That "black tar" is a bad sign. Without proper analytical verification (HPLC/LC-MS/NMR), there's no way to know what's actually in that black residue. That usually indicates polymerization and decomposition products, not a clean alkaloid salt which are usually off-white to tan in color. Also, reaction control is missing. Light intensity, oxygen flow, temperature control, and solvent purity matter a lot for these oxidations. And lastly, quenching steps like the ones described do not guarantee removal of reactive oxygen species or toxic byproducts.

At a high level, the reason this kind of oxidation is hard to control comes down to indole chemistry + singlet oxygen being very reactive and non-selective.

I still feel it and it keeps wd away
Do you know about 5,6-dichloro-desmethylchlorphine, aka: SR-17018? Here's a little bit of info… I think it's worth knowing about and spreading info about it, anyways:
It's not something one can use to get high, but it helps lower tolerance and dependence more rapidly while abating withdrawal symptoms.
 
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I'd be cautious with this as it's not a validated or peer-reviewed method for producing 7-OH-mitragynine. Kitchen chemistry oxidations often generate complex byproducts that aren’t characterized, and the safety claims are shaky. Singlet oxygen handling, prolonged oxygen bubbling, and hot-plate drying can all create additional unknown oxidation products. Quercetin and citric acid don't guarantee safety and cannot retroactively make the reaction selective.

From the technical perspective, singlet oxygen reactions on complex alkaloids rarely give one clean product. You typically get a mixture of over-oxidized and rearranged compounds. That "black tar" is a bad sign. Without proper analytical verification (HPLC/LC-MS/NMR), there's no way to know what's actually in that black residue. That usually indicates polymerization and decomposition products, not a clean alkaloid salt which are usually off-white to tan in color. Also, reaction control is missing. Light intensity, oxygen flow, temperature control, and solvent purity matter a lot for these oxidations. And lastly, quenching steps like the ones described do not guarantee removal of reactive oxygen species or toxic byproducts.

At a high level, the reason this kind of oxidation is hard to control comes down to indole chemistry + singlet oxygen being very reactive and non-selective.


Do you know about 5,6-dichloro-desmethylchlorphine, aka: SR-17018? Here's a little bit of info… I think it's worth knowing about and spreading info about it, anyways:
It's not something one can use to get high, but it helps lower tolerance and dependence more rapidly while abating withdrawal symptoms.
So do you think that even once freebased, it'll have a lot of alkaloidal byproducts unsafe to consume? I kind of assumed that the Mitragynine citrate would come out to be goopy. And to be real its not exactly "black" more of a dark orange color that got somewhat harder to see when cooked down This orange lines up alright with my experience with freebase 7 oh

I also didn't use isolated mit; i used like 65% mit total alkaloid extract, which definitely gave some byproducts
Mostly I wasnt worried about oxidant byproducts so much as the oxidizer itself, for the reason that everything you consume is going to oxidize in some way or another before you eat it, but are the oxidized products formed more toxic than the normal alkaloids?

Maybe adding ascorbic acid would help get rid of the remaining oxidant? Just kind of spitballing
I also have access to Chloroform, another documented quencher of singlet oxygen, but im not sure how much it would help after using 3 other quenchers
:shrug:
Still should probably freebase as then I could be sure (rose bengal isnt soluble in NPS)
Lastly; if the freebase step wouldnt result in a safe product; do you think that running it through a chromatography column would do the trick? Should only elute one compound at a time, no? To be real though I should just get one and run the TAE through it to isolate the mit prior to doing any chemistry with it.

Thanks for being so helpful and sorry for all the questions; feel free to tell me to fuck off lol.
 
I've been taking plain leaf kratom for the last several years (sadly) and I'm again at the point where if I don't have it every morning I suffer withdrawals. About a year ago I posted a thread about how I used ivermectin because I found out I was infested with Ascariasis (common human roundworm). My worm load was heavy enough that I had one come out of me in the shower.

Since initially getting rid of the worms I've been very careful about trying not to get re-infested. I don't touch the bottom of my boots anymore, deep cleaning of the house, really careful about washing food before preparing it, no longer eat out that often, regular hand washing, always wear gloves when working with animals and everything else. Yet I was still getting symptoms of infestation and having to take ivermectin every 2-3 months. I know when I start getting the morning coughs and lactose intolerance again and every time I take ivermectin I'll see more than a few worms come out 3-4 days later.

Since I'm a junkie I didn't give any thought to the leaf I'm shoving into my mouth 3-5 times a day. After all I need it to function. But I got curious and sent a sample off recently. I wasn't surprised when the results came back: It was filled with ascariasis eggs. Makes sense I guess because the leaves no doubt end up on the ground before processing and who knows how many unwashed hands touch them before they find their way to me.

While I'd probably get infected anyway as it's nearly impossible to go through life where I live without coming into contact with the eggs shoving thousands of them into my mouth every day certainly isn't helping matters. Since I'm not going to quit kratom any time soon I've decided to step up my regime of ivermectin to once every 1-2 months in the mean time.

Just putting it out there for everyone else. I was infested with round worms for decades before I had one come out naturally last year (I know because they cause lactose intolerance). My worm burden went through the roof after I started taking kratom daily around 2018. Since my lactose intolerance got much worse starting a few months after that and I started suffering from morning coughing. Which I attributed to getting older and smoking tobacco for so long. But it wasn't the smoking it was the juvenile worms migrating from my intestines to my lungs after hatching. So many were hatching out from my daily intake (50-60 grams per day at one point).

At the moment I'm currently trying to slowly work my way down by reducing intake of kratom leaf. I'm doing to 2-5 grams per dose instead of 10-25 grams per dose now. It is going to take a long time and I'm unsure if I'll ever be able to quit. I'm terrified of it getting banned before I work my way off of it. If they ban it in my state I'm not sure what I'm going to do. Since I require it to function now and I'm sick of paying for it. I have a drawer in my desk where I store the old bags and last time I added them up there was over $5k worth of used bags in there.
 
So do you think that even once freebased, it'll have a lot of alkaloidal byproducts unsafe to consume? I kind of assumed that the Mitragynine citrate would come out to be goopy. And to be real its not exactly "black" more of a dark orange color that got somewhat harder to see when cooked down This orange lines up alright with my experience with freebase 7 oh

I also didn't use isolated mit; i used like 65% mit total alkaloid extract, which definitely gave some byproducts
Mostly I wasnt worried about oxidant byproducts so much as the oxidizer itself, for the reason that everything you consume is going to oxidize in some way or another before you eat it, but are the oxidized products formed more toxic than the normal alkaloids?

Maybe adding ascorbic acid would help get rid of the remaining oxidant? Just kind of spitballing
I also have access to Chloroform, another documented quencher of singlet oxygen, but im not sure how much it would help after using 3 other quenchers
:shrug:
Still should probably freebase as then I could be sure (rose bengal isnt soluble in NPS)
Lastly; if the freebase step wouldnt result in a safe product; do you think that running it through a chromatography column would do the trick? Should only elute one compound at a time, no? To be real though I should just get one and run the TAE through it to isolate the mit prior to doing any chemistry with it.

Thanks for being so helpful and sorry for all the questions; feel free to tell me to fuck off lol.
No, I'm just trying to be respectful of site rules. They don't want us discussing synthesis on here, and while I'm trying to make sure it's within the context of harm reduction, I'm not trying to push my luck. So I'll just say that I don't know how bad for you those oxidation species are, but it doesn't seem far fetched that they could be. Yes, chromatography would absolutely be a move in the right direction so you can isolate and purify and thus help ensure safety. You only just one body in life. Treat it well, take care of it. Don't take unnecessary risks with it for sure. Bee careful. One love.
 
No, I'm just trying to be respectful of site rules. They don't want us discussing synthesis on here, and while I'm trying to make sure it's within the context of harm reduction, I'm not trying to push my luck. So I'll just say that I don't know how bad for you those oxidation species are, but it doesn't seem far fetched that they could be. Yes, chromatography would absolutely be a move in the right direction so you can isolate and purify and thus help ensure safety. You only just one body in life. Treat it well, take care of it. Don't take unnecessary risks with it for sure. Bee careful. One love.
Oh my bad man I thought it was ok as long as stuff was legal 😅 I thought I had seen synthesis discussions on here before but it could have been ten other boards I frequent.
Thank you for the kind words. Youre a good soul. I appreciate all your insight 🙏
 
No, I'm just trying to be respectful of site rules. They don't want us discussing synthesis on here, and while I'm trying to make sure it's within the context of harm reduction, I'm not trying to push my luck. So I'll just say that I don't know how bad for you those oxidation species are, but it doesn't seem far fetched that they could be. Yes, chromatography would absolutely be a move in the right direction so you can isolate and purify and thus help ensure safety. You only just one body in life. Treat it well, take care of it. Don't take unnecessary risks with it for sure. Bee careful. One love.
happy to report that when I went back to scrape it up it had somewhat hardened (what was exposed to air at least) and turned that tan color you mentioned. Looks almost exactly like brown sugar but slightly wetter and getting more golden in color as it dries. Kinda beautiful actually. Chromatography column on the way currently. Cant wait :)
 
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Take very low doses throughout the day, like every hour

Best way to use kratom?
 
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