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  • BDD Moderators: Keif’ Richards

loperamide doses?

koolman69420

koolman69420

Bluelighter
Joined
Feb 4, 2026
Messages
145
Location
east coast USA
i know this drug is insanely stupid and insanely dangerous but i was just wondering doses for it because im out of the real thing
 
^^Yeah, depends on what opiod you usually take and how much?

Generally rule of thumb is if it's you're first time, never take more than a 24 hr max. dose at once the first time, so I wouldn't take more than 16mg
 
koolman69420 said:
is it possible to get a high off it
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Yesss, but the dose you'd have to take for that is so high you'd be at serious risk of life-threatening arrhythmia due to how highly cardiotoxic it is. Your heart can stop. People have died.
Incredibly not worth it.
 
You can get high on it, feels kind of like a really dirty methadone type feeling + your heart is fluttering and pounding on high doses.

This is very stupid, loperamide causes prolongation of QT-intervals and is highly cardiotoxic, even if you dont die ive read studies of people getting long term prolongation of the QT-intervals.

I tell you, no matter how much loperamide is in your system you will shit your pants when you get an ECG and realize your heart is fucked for life and your risk of arrythmias, TdP, heart attacks, seizures and AV-block is massively amplified…
 
TheLightBringer said:
You can get high on it, feels kind of like a really dirty methadone type feeling + your heart is fluttering and pounding on high doses.

This is very stupid, loperamide causes prolongation of QT-intervals and is highly cardiotoxic, even if you dont die ive read studies of people getting long term prolongation of the QT-intervals.

I tell you, no matter how much loperamide is in your system you will shit your pants when you get an ECG and realize your heart is fucked for life and your risk of arrythmias, TdP, heart attacks, seizures and AV-block is massively amplified…
Click to expand...

Yeah I'd rather go through WD than risk fucking your heart up, it's just not worth it!
 
evo4ever said:
Yeah I'd rather go through WD than risk fucking your heart up, it's just not worth it!
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I’m going to chime in here.
Loperamide almost destroyed me. It did fucj with my whole system tho not just my heart. I was parched of potassium and magnesium. It took forever to get right again.

Anyways this is a harm reduction forum so don’t do this. Threshold dose for loperamide is 24mg. Some might say that’s a normal dose. But that’s for someone who is opioid naive. A tolerant user would require more and it’s seriously fucking dangerous.

I miscounted pills one night when I was really sad. I had taken a benzo that I later found out was not oxycodone.
I got home and took another 24 mg of loperamide and fucking od’d in my bedroom didn’t wake up for three days. My dad said it sounded like I was dying. I heard my sister crying wondering if I was still alive. My tongue was so swollen and dry and covered in sores when I woke up. I pissed directly into my bed.

It’s unreal the damage it can do with even a slight increase in dosage or optimizing its ability to pass the blood brain barrier.

The dosing is so strict to even reduce the harm. Getting high off of it is playing with your future.

It also has an incredible half life and you have to withdrawal for months.

I really would just not do this. It’s so stupjd and it feels so shameful to be popping blister packs of diarrhea pills.

But thats
My attempt to reduce the harm to your person by providing a threshold dose and advising that even doubling that dose has caused overdose in some persons. Myself. I feel you should know that.
 
helpingout said:
I’m going to chime in here.
Loperamide almost destroyed me. It did fucj with my whole system tho not just my heart. I was parched of potassium and magnesium. It took forever to get right again.

Anyways this is a harm reduction forum so don’t do this. Threshold dose for loperamide is 24mg. Some might say that’s a normal dose. But that’s for someone who is opioid naive. A tolerant user would require more and it’s seriously fucking dangerous.

I miscounted pills one night when I was really sad. I had taken a benzo that I later found out was not oxycodone.
I got home and took another 24 mg of loperamide and fucking od’d in my bedroom didn’t wake up for three days. My dad said it sounded like I was dying. I heard my sister crying wondering if I was still alive. My tongue was so swollen and dry and covered in sores when I woke up. I pissed directly into my bed.

It’s unreal the damage it can do with even a slight increase in dosage or optimizing its ability to pass the blood brain barrier.

The dosing is so strict to even reduce the harm. Getting high off of it is playing with your future.

It also has an incredible half life and you have to withdrawal for months.

I really would just not do this. It’s so stupjd and it feels so shameful to be popping blister packs of diarrhea pills.

But thats
My attempt to reduce the harm to your person by providing a threshold dose and advising that even doubling that dose has caused overdose in some persons. Myself. I feel you should know that.
Click to expand...

Did you do any permanent damage?
 
helpingout said:
I’m going to chime in here.
Loperamide almost destroyed me. It did fucj with my whole system tho not just my heart. I was parched of potassium and magnesium. It took forever to get right again.

Anyways this is a harm reduction forum so don’t do this. Threshold dose for loperamide is 24mg. Some might say that’s a normal dose. But that’s for someone who is opioid naive. A tolerant user would require more and it’s seriously fucking dangerous.

I miscounted pills one night when I was really sad. I had taken a benzo that I later found out was not oxycodone.
I got home and took another 24 mg of loperamide and fucking od’d in my bedroom didn’t wake up for three days. My dad said it sounded like I was dying. I heard my sister crying wondering if I was still alive. My tongue was so swollen and dry and covered in sores when I woke up. I pissed directly into my bed.

It’s unreal the damage it can do with even a slight increase in dosage or optimizing its ability to pass the blood brain barrier.

The dosing is so strict to even reduce the harm. Getting high off of it is playing with your future.

It also has an incredible half life and you have to withdrawal for months.

I really would just not do this. It’s so stupjd and it feels so shameful to be popping blister packs of diarrhea pills.

But thats
My attempt to reduce the harm to your person by providing a threshold dose and advising that even doubling that dose has caused overdose in some persons. Myself. I feel you should know that.
Click to expand...
that sounds like an allergic reaction have you done it before
 
Is Kratom legal where you live? Infinitely better for what you're dealing with than Loperamide. You posted this Thursday. Hope you are okay.
 
helpingout said:
I’m going to chime in here.
Loperamide almost destroyed me. It did fucj with my whole system tho not just my heart. I was parched of potassium and magnesium. It took forever to get right again.

Anyways this is a harm reduction forum so don’t do this. Threshold dose for loperamide is 24mg. Some might say that’s a normal dose. But that’s for someone who is opioid naive. A tolerant user would require more and it’s seriously fucking dangerous.

I miscounted pills one night when I was really sad. I had taken a benzo that I later found out was not oxycodone.
I got home and took another 24 mg of loperamide and fucking od’d in my bedroom didn’t wake up for three days. My dad said it sounded like I was dying. I heard my sister crying wondering if I was still alive. My tongue was so swollen and dry and covered in sores when I woke up. I pissed directly into my bed.

It’s unreal the damage it can do with even a slight increase in dosage or optimizing its ability to pass the blood brain barrier.

The dosing is so strict to even reduce the harm. Getting high off of it is playing with your future.

It also has an incredible half life and you have to withdrawal for months.

I really would just not do this. It’s so stupjd and it feels so shameful to be popping blister packs of diarrhea pills.

But thats
My attempt to reduce the harm to your person by providing a threshold dose and advising that even doubling that dose has caused overdose in some persons. Myself. I feel you should know that.
Click to expand...
Had a similar experience, I took a high dose on the tail end of an amphetamine binge to try and ease the comedown not knowing what I was getting myself into. Think I did 48mg while relatively Opioid naive. About 90 minutes later I started panicking cause my heart was skipping beats and fluttering, the opioid high was fairly mild as well and I was not able to enjoy it.

Ended up panicking and calling an ambulance because I was dizzy and felt like I was about to pass out when I stood up.

The next day after only 3 hours of sleep or so I thought I was good to take 1mg alprazolam and smoke some weed, and even though I didnt ”feel” much of the loperamide it seriously fucked me up and I started almost nodding out but not in a good way, kind of like that cold sedating dirty fent feeling instead of the warm morphine feeling.
 
TheLightBringer said:
Had a similar experience, I took a high dose on the tail end of an amphetamine binge to try and ease the comedown not knowing what I was getting myself into. Think I did 48mg while relatively Opioid naive. About 90 minutes later I started panicking cause my heart was skipping beats and fluttering, the opioid high was fairly mild as well and I was not able to enjoy it.

Ended up panicking and calling an ambulance because I was dizzy and felt like I was about to pass out when I stood up.

The next day after only 3 hours of sleep or so I thought I was good to take 1mg alprazolam and smoke some weed, and even though I didnt ”feel” much of the loperamide it seriously fucked me up and I started almost nodding out but not in a good way, kind of like that cold sedating dirty fent feeling instead of the warm morphine feeling.
Click to expand...
i think its for withdrawls so getting high wouldnt be getting sober
 
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