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Misc Lamotrigine (Lamictal) thread

abefourth said:
One interesting example of being both a medical and explosive use of a substance would be nitroglycerin. It would be completely wild if Lamictal were to have a similar profile.
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Absolutely.

If you didn't already know, there is a story that the vasodilatory action of nitrate esters was discovered after it was noted that munitions workers were experiencing unexplained syncope (fainting) and that was discovered to be postural hypotension i.e. people would stand up suddenly... and fall over and in turn that was shown to be the nitroglycerin.

On reflection, I think Lamical may deflagrate rather than detonate. But it has always seemed a bit odd to me that a chemical (after all, drugs are just a subset of chemicals) that is produced at large scales isn't required to go through any testing or even calculations to just check that there isn't a potential risk.

I mean, we have seen some really serious accidents because someone tested a chemical at bench-scale and just assumed that the data would apply at the tonne scale. T2, Serveso and so on.
 
I wish there was more studying of lamictal. I think it's a substance that could be of great use to a lot of people.
 
CfZrx said:
Does this mean I should not smoke while on Lamictal??
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Well, it looks like it may be 'energetic' so beware, it may detonate. I checked, nobody has ever thought to test if lamotragine does pose an explosion risk. Lots not nitrogens so while the oxygen-balance is bad, exothermic runaway from deflagration may occur.
 
My ex-fiancee took lamictal and swore by it. She loved the stuff. She was a Type 1 diabetic and bipolar I (allegedly, I never even once saw her crash out, so either it worked or she was misdiagnosed). Also took xanax which she constantly tried to offer me when I was clean.
 
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