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  • Trip Reports Moderator: M!$ter-ED

DOB (Unknown Dose) - Second Time - Dosing Error with Shulgin‘s Behemoth

Psychestim

Bluelighter
Joined
Feb 8, 2021
Messages
464
disclaimer: very long report


Background information:

- sex: male
- age: 28
- weight: 73 kg
- setting: nervous, apprehensive but excited
- set: at home alone, later with my current girl acquaintance
- medication: 20 mg telmisartan, not medically necessary but taken for improved vascular health and other benefits. It’s also been extremely helpful for PEA-related headaches.

DOB is one of those molecules that I had always dreamed of trying when I first got into the RC scene and started reading about Alexander Shulgin. It‘s one of those chemicals that I somehow connected to on a, let‘s say, spiritual level for a lack of better words, long before ever trying it. The daunting duration of action, the reportedly rough body load, the raw stimulation, and the overall intensity always made it sound like a challenge that I eventually wanted to take on. Although the question had always been, when is the right time? I have tried a few other DOx compounds like DOF, DOC, DOM, DOIP, as well as other long-lasting PEA‘s like TMA-2, mescaline, 2C-T-4, 2C-T-7, 2C-E, 2C-EF etc. to familiarize myself with this space but never felt truly ready for it.

A friend of mine gifted me ~65 mg of some VVS-looking DOB•HCl crystals about two years ago, and upon receiving them, I made a 0.2 mg/mL microdosing solution with a few milligrams of what I had received. I tested it once at 1 mL after making the solution and had an expected reaction to it. Nothing to write home about, but it was a light-hearted, fun, stimulating and socially enhancing threshold dose. After that, I let the solution sit in my fridge for 1.5-2 years in a blue dropper bottle.

Two nights ago, while I was a little high on THC edibles scrolling on my computer I thought of it again and on a whim decided that tomorrow would be the right day. I was bored, had nothing to do the next day, and had been postponing my DOB experiments for far too long. At the end of the day, it was only a small-to-moderate dose, and if you don’t just go for it, you’ll never do it. I set my alarm for 6 AM the next day to clean the apartment, go grocery shopping, and prepare myself for my 1 mg DOB dose.


DOB•HCl (unknown dose, oral) / Report:

T:00:00: -
After finishing my morning routine, I grabbed the dropper bottle from the fridge and drew up 5 mL (5 mL × 0.2 mg/mL = 1 mg) with a syringe. I poured the liquid into a small beaker, diluted it with some water, and immediately drank about 2/3 of the contents.

T:00:15: +
Wait, why am I already feeling something? There is substantial mydriasis and my head is warm and tingly. I look into the beaker again and notice tiny particles floating around, I am unsure whether those particles are undissolved DOB crystals or if it‘s fine dust because the beaker had been sitting in my cupboard for quite a while. I am getting nervous, did I screw something up? Is this the first mistake in my ten years of experimenting with drugs? Shit, I forgot to shake the bottle before taking out my dose. I check on the dropper bottle again and pour the contents out in a glass to see if there is undissolved DOB floating around but I can‘t really see anything unusual. I also check on my older solutions of DOC and DOIP but they look fine too. I text an online friend about my potential dosing mishap, but he asks the right questions to comfort me. The DOB•HCl is very unlikely to precipitate at this concentration and that even if I‘d consumed the whole bottle of DOB it wouldn‘t be fatal. I am just feeling the effects quickly because it was in solution and I had an empty stomach. I am swirling the beaker but the particles are just floating around without dissolving. I deem my uncertainty as invalid and drink the remaining 1/3 of the beaker.

T:00:45: +
The euphoria ramped up significantly in the past thirty minutes, I am feeling uplifted, albeit physically glued to the couch. I drink some magnesium water to counteract the potential muscle tension, vasoconstriction and other negative body effects the DOB might induce in the next hours. I put on some music and start to relax into the experience. The music sounds wonderful, I am enjoying myself.

T:01:15: ++
Damn, this is getting strong. I am already questioning myself and the decision to trip today. The visuals have been mild so far, some minor drifting and slow morphing here and there but the headspace is coming on strong. It reminds me of my challenging 2C-E experience a few years ago where I tripped solo on a moderate dose and was getting completely overwhelmed. This is already having shades of that. Don‘t panic now, you wanted this, try and go with the flow. This is going to be over soon.. ah, come on, who am I kidding.

T:01:45: ++
The OEV’s have now transformed from drifting and morphing to geometric patterns on the wall. When I close my eyes, I’m greeted by beautiful colors, moving structures, abstract shapes, and buildings. The stimulation is now very apparent, I am restless and my mind is wandering off. My stomach growls, but my appetite is suppressed. I go to the kitchen counter and grab a bag of salted pistachios. I frantically peel them one by one with a blank stare and shove them into my mouth. The salty taste is good, but it doesn‘t distract me from the fact that this experience is getting stronger by the minute. I grab some dark chocolate and a banana, they taste amazing as well, but I need to focus on my breathing.

T:02:00: +++
I text the same friend, explaining that my reality is warping and that the headspace is consuming me. He sends reassuring messages and a few trippy pictures that keep me occupied. The visuals are absolutely insane, way more than I expected there to be at this dose. My body is a bit uncomfortable, I am unsure what to do with all this stimulation but there is no nausea luckily. I feel cold, my heart rate is elevated, and I’m hypomanic and euphoric, yet uneasy because this is more than I anticipated. I realize it’s only been two hours since ingestion and the effects haven’t even peaked. I react and eat a half tablet of triazolam (0.125mg) that was lying on my desk.

T:02:30: +++
This is absolutely insane! This drug is absolutely insane. I close my eyes and I‘m entering hyperspace, the visual hallucinations are so intense, I think the only thing more impressive was when I vaporized some DMT on LSD a little over a year ago. My body is twitching and I am now very manic. The drug has completely overtaken my psyche, I am only an observer now. The small dose of Halcion barely affects me, perhaps it made me a bit more careless but the strength of the DOB was not diminishing at all.

T:03:00: +++
From here on it gets a little blurry. I quickly went to the toilet for a pee and notice that the skin on my arms looks yellow and dead, I have goosebumps and I am cold. My fingers look scrawny and it feels like I am withering away. I drink some water and run back to my couch to lie down. The stimulation is getting out of control. I am clenching my fists and my body in full force, it feels like I am channeling all the energy into the psychedelia in what feels like a positive feedback loop. I close my eyes and see myself from an outside perspective in the fetal position covered in fractals. My emotions are switching back and forth really quickly. I feel angry at myself but have no choice but to surrender.

T:03:30: +++(+)
I can‘t highlight enough how unique the DOB headspace is. I have never experienced such pure mania and this piercing mental sharpness on any other psychedelic. This apparent clearheadedness slowly fades into confusion. I am pressed into the couch so forcefully, asking myself if I were at peace, would I know that I might die right now? I remain lucid enough to know that I wasn‘t actually going to die but the DOB was stripping away my sanity. At this moment, I begin to sense serenity and drift into a visual landscape and odd scenarios I can barely describe. I experience clean euphoria and synaesthesia. The music dictates my CEV’s and my feelings. I feel guilty for allowing myself to feel such hedonistic sensations, but the guilt is quickly replaced by a sense of egotistical empowerment: I am on top of the world and allowed to feel however I want. I notice the switch from fear to grandiosity and am amazed.

T:04:00-06:45: +++(+)
I am shifting in and out of consciousness, I have almost no base in reality. Things I do are happening because of automatism, I text the girl I‘ve been seeing (let’s call her M) that I was fine, I eat an orange or two, I go to the toilet again, and briefly stand by the window for fresh air. The street outside looks surreal, bright, and heavily distorted. At one point, I think I take another half tablet of triazolam (0.125 mg), but I am unsure if I actually do. I know that anything I do is out of my control. I lie down on the couch again and alternate between short-lasting fugue states and perceived clarity. Immense pleasure courses through me. Somewhere in all this, I feel as if I am having a religious or spiritual experience, but judging by my partial amnesia the triazolam likely did block a few things out and made me more distant to what was happening around me. Although it‘s still possible that the DOB itself causes these attention lapses. I remember pointing to my ceiling lamp and it folding up into a portal to heaven.

T:06:45: +++
I start to regain consciousness. It feels like awakening from an intense dream or slowly recovering parts of my memory after a k-hole. I am disoriented but immensely grateful. I am so happy. I feel reborn.

T:07:00: +++
I jump up from the couch laughing in absolute disbelief. Holy shit. What just happened. My 2C-E experience was more negative, but this was far more encompassing and intense. Unsure what exactly happened I immediately go back to the fridge and pour out 5mL of the solution onto some aluminium foil that I tared beforehand to evaporate the solvent off on the induction burner. In my hastiness, I also eat something and do other nonsensical things, completely forgetting to weigh the residue. I become confused by the scattered aluminum foil and throw all of it away, not that measuring the tiny, possibly improperly dried amount, would be accurate anyway.

T:08:00-11:00: +++
I was listening to Harry Styles‘ album Fine Line on repeat during this experience. It seems I put it on some time during the peak because it gave me comfort. The visuals at this point are still strong but nowhere near the madness that unfolded three hours ago. The euphoria is incredible, the plateau phase began somewhere around here and I am sensing security. I am reading about DOB, talking about DOB with other people online, I feel an urge to socialize and tell people about DOB but I feel vulnerable and I‘m glad I am in my safe space. My stomach hurts a bit and I manage to eat some bread with cheese and warm up a heating pad for my stomach.

T:11:00: ++
I don’t know how time flies by so quickly, just a while ago I was counting minutes. The stimulation is very prominent, and I am almost jogging around my apartment doing chores, feeling light-hearted. DOB is the most insane psychedelic I have ever tried.

T:12:00: ++
M came over just now. She is really caring, calm and reassuring, we chill and cuddle on the couch together. I tell her what I remember from the experience while listening to music. I am trying to describe the visuals to her, and it feels like I am talking in hyper speed. She tells me that apart from my huge pupils I look and behave normally. My thoughts seem to be much faster and more chaotic than the words I am actually saying.

T:13:00-16:00: ++
The plateau is really enjoyable, the time practically flies by. We talk enthusiastically and I am switching between states of hypomanic stimulation and exhaustion. I am tired but too wired to actually rest. She falls asleep in my arms while I am trying to figure out what exactly happened.

T:16:00-19:00: +
M goes to bed and I remain on the couch for a while just passing the time and waiting for the residual stimulation to wear off. Eventually I conclude that I’m ready for bed and eat a tablet of triazolam (0.250mg). I join her in bed but am forced to stay awake for a while.

T:19:00-22:00: +
I sleep lightly for three hours and wake up dizzy from the benzodiazepine but my mind is wide awake.

T:23:00-25:00: +
I am unable to fall asleep again and just stare at the ceiling for a while before getting up and hopping into the shower.

T:26:00: -
My pupils are returning to normal size, and I feel really tired. I nap for thirty minutes but will stay awake until 11 PM (T:38:00) of the same day.


After-effects:
The rest of the day is spent in relative silence and is fairly uneventful. I am emotionally flat and develop a headache 28 hours after intake, which I resolve with 400 mg ibuprofen. I feel slightly nauseous throughout the day, but food, water, and rest take care of it. I notice frequent urination, even though I did not drink large amounts of water that day.


—————————————————————————


Conclusion:

Fortunately nothing tragic happened and I am glad that everything went fine. I will be giving myself a big time to rest and to integrate the experience. The big question remains, what on earth happened? Was it stupid of me to try DOB alone? Yes. Was it forseeable that 1 mg would induce such an extreme response? Not really. Of course there is a chance that things go not as planned but this was far more than I ever anticipated. I brought my dropper bottle with me to my university where I had access to a 0.001 mg lab balance, tared an eppi tube and micropipetted out 0.5 mL (= 0.1 mg DOB•HCl) of the solution. I put a small piece of aluminium foil over it, poked a couple tiny holes in it and let the solvent evaporate. When I weighed the eppi again I was shocked to see that instead of the expected 0.100 mg the residue weighed 0.456 mg. How did the concentration increase by over 4.5x? This would mean that over two years >75% of the solvent evaporated, which is impossible judging by the amount of solution I still have in the bottle so I still have no explanation for what exactly happened. The only thing I can conclude is that my dose range was somewhere between 1 mg and 4.56 mg. Use this as a reminder to check on your older solutions and use tight bottles where solvent evaporation is minimal. Always label the fluid levels and renew your stock solutions every once in a while. Dose responsibly, and have a sitter + sedatives ready when using psychedelics.

Psychestim
 
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Fascinating. I'm glad you're safe and had a reasonably positive trip all things considered. Had you not considered the possibility of solvent evaporation and eliminated it, that would my my immediate assumption. I've read a couple reports lately of people having similar experiences with refrigerated solutions in dropper bottles that has partially evaporated. I've narrowly dodged it myself, as I've had multiple refrigerated/freezer-stored solutions in dropper bottles evaporate completely in less than a year. If they'd still had liquid, I would likely have used them. I've even had tightly sealed plastic and glass (rubber gasket-sealed) evaporate dramatically. I currently have some DOiP that I fully intended to test only to see that the plastic bottle has actually *crumpled* during storage, which seems like it should violate a law of thermodynamics. Needless to say, I won't be taking any of that until I can rotovap the solution and re-weigh it.

But if that's not the case, then maybe it was just your destiny to trip uncommonly and inexplicable hard that day.
 
Like the little girl said in the care.com advertisement: "Very interesting!!!"

Is it possible to fry a dark chocolate covered banana? Have to ask the mythbusters?
 
—————————————————————————


Conclusion:

Fortunately nothing tragic happened and I am glad that everything went fine. I will be giving myself a big time to rest and to integrate the experience. The big question remains, what on earth happened? Was it stupid of me to try DOB alone? Yes. Was it forseeable that 1 mg would induce such an extreme response? Not really. Of course there is a chance that things go not as planned but this was far more than I ever anticipated. I brought my dropper bottle with me to my university where I had access to a 0.001 mg lab balance, tared an eppi tube and micropipetted out 0.5 mL (= 0.1 mg DOB•HCl) of the solution. I put a small piece of aluminium foil over it, poked a couple tiny holes in it and let the solvent evaporate. When I weighed the eppi again I was shocked to see that instead of the expected 0.100 mg the residue weighed 0.456 mg. How did the concentration increase by over 4.5x? This would mean that over two years >75% of the solvent evaporated, which is impossible judging by the amount of solution I still have in the bottle so I still have no explanation for what exactly happened. The only thing I can conclude is that my dose range was somewhere between 1 mg and 4.56 mg. Use this as a reminder to check on your older solutions and use tight bottles where solvent evaporation is minimal. Always label the fluid levels and renew your stock solutions every once in a while. Dose responsibly, and have a sitter + sedatives ready when using psychedelics.

Psychestim



That is a quite the mystery with the solution!? My method was always to not make more into solution than was going to be used in the next couple of months -- as I have heard similar horror stories (most human error but some still ???'s like this)
(Yes he took into account that some of the solvent could have evaporated -- doesn't really add up math wise if I understood correctly)

" How did the concentration increase by over 4.5x? This would mean that over two years >75% of the solvent evaporated, which is impossible judging by the amount of solution I still have in the bottle." -- and I got nothing other than that is why I would make a month or two into solution at once -- usually potency would be lost if you messed up IME but ?

I just read the title and didn't realize it was in trip reports and was gunna say "No don't do it!" lol I once took DOx? dosage (well it came from a festi) -- Took that ish on a Friday and was still semi tripping when I had to go to court on Monday. Was not a good look!

Fortunately court was another 8 hours away and by the time I got there things had chilled mostly --- last time I messed with DOx. I do not have the lab access nor a source solid enough for something that lasts that long!

EDIT *** Yes the body load was horrible (For me) I couldn't eat for about 24 hours - just got a denny's burger in a half hour outside of court lol****** Worse than 2c-i / 2c-b
 
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Fascinating. I'm glad you're safe and had a reasonably positive trip all things considered. Had you not considered the possibility of solvent evaporation and eliminated it, that would my my immediate assumption. I've read a couple reports lately of people having similar experiences with refrigerated solutions in dropper bottles that has partially evaporated. I've narrowly dodged it myself, as I've had multiple refrigerated/freezer-stored solutions in dropper bottles evaporate completely in less than a year. If they'd still had liquid, I would likely have used them. I've even had tightly sealed plastic and glass (rubber gasket-sealed) evaporate dramatically. I currently have some DOiP that I fully intended to test only to see that the plastic bottle has actually *crumpled* during storage, which seems like it should violate a law of thermodynamics. Needless to say, I won't be taking any of that until I can rotovap the solution and re-weigh it.

But if that's not the case, then maybe it was just your destiny to trip uncommonly and inexplicable hard that day.
I am pretty sure the dose was below 4.5 mg but significantly more than 1 mg. It had been stored in the fridge for so long that solvent evaporation is likely. I simply did not anticipate such a potentiation. I have no idea why the mass of the residue was so heavy. Maybe there was some residual water trapped inside the crystal structure. The scale could have been off, which I doubt because it was calibrated. There could have been some other substances in the vodka that did not evaporate, which is also doubtful since it was clear 80 proof vodka. I think the first explanation is the most likely. Water can be stubborn, so I probably would have needed to remove the last bit with a proper vacuum pump. I am glad everything turned out okay. The moral of the story is not to store stock solutions for two years in a dropper bottle.

Interesting report, was the body load as bad as people say or was it manageable?
I don't think it's bad, but it is heavy and highly stimulating so for sensitive people it could certainly be too much. I think it's worth a try though, DOB is an extraordinary psychedelic.
 
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