• The Dark Side 💕 Welcome Guest 💕
    Posting Rules Bluelight Rules
    Notable Threads Urgent Hotlines
    Bereavement Mindfulness
    Suicide Support Anger Management
  • TDS Moderators: AlphaMethylPhenyl | paranoid android

Coming off Invega/Xeplion (paliperidone) injections v11

Status
Not open for further replies.
anonymoususer777 said:
Thak you for giving us hope. Are you 100% recovered like you were before invega? Did you have muscle soreness that didnt heal and body heating up during your recovery?
Click to expand...
You are very welcome. I would say I don‘t feel the Invega damage anymore, I am back to normal yes. I never had my body heat up, and never had muscle soreness, I did have muscle twitches though, which were very distressing. They went away.
 
Last edited:
RisperdalConsta50mg said:
I can’t get why some people recover in 6-9 months while other are struggling 16 months after with less injection.
Click to expand...
It’s not just about the quantity of the drug; it’s about the molecular scar left behind. Recovery isn't linear math. The reason some struggle for 16+ months even with fewer injections lies in two specific mechanisms: DeltaFosB and G-Protein Coupling.
The 'Stuck Switch' (DeltaFosB): When you take antipsychotics, a transcription factor called DeltaFosB accumulates in the neurons. It acts like a molecular 'memory' of the blockade. Even after the drug is gone, DeltaFosB remains stable in the nucleus for a long time, forcing your DNA to keep producing altered receptors. In some people, this protein degrades very slowly (12-18 months), causing prolonged symptoms regardless of the initial dose.
High Affinity Trap (G-Proteins): The issue isn't just receptor number (density), it's sensitivity. In your case, the G-Proteins inside the cell might be hyperactive, locking your D2 receptors into a 'High Affinity State.' This means even tiny amounts of dopamine create 'noise' rather than a clear signal. This uncoupling process takes much longer than simply flushing the drug out.
So, you aren't 'broken.' Your brain just accumulated more DeltaFosB or has a stiffer G-Protein adaptation, which requires a longer (but finite) time to reset."
This is the information ı get from gemini
 
RisperdalConsta50mg said:
I can’t get why some people recover in 6-9 months while other are struggling 16 months after with less injection.
Click to expand...
Timelines vary, the majority show some recovery between 8 to 12 months but longer periods are also frequently seen. I have seen numerous reporting 2 year recovery times. See if smoking marijuana helps you feel better and relax.
 
fuqrisperdal said:
It’s not just about the quantity of the drug; it’s about the molecular scar left behind. Recovery isn't linear math. The reason some struggle for 16+ months even with fewer injections lies in two specific mechanisms: DeltaFosB and G-Protein Coupling.
The 'Stuck Switch' (DeltaFosB): When you take antipsychotics, a transcription factor called DeltaFosB accumulates in the neurons. It acts like a molecular 'memory' of the blockade. Even after the drug is gone, DeltaFosB remains stable in the nucleus for a long time, forcing your DNA to keep producing altered receptors. In some people, this protein degrades very slowly (12-18 months), causing prolonged symptoms regardless of the initial dose.
High Affinity Trap (G-Proteins): The issue isn't just receptor number (density), it's sensitivity. In your case, the G-Proteins inside the cell might be hyperactive, locking your D2 receptors into a 'High Affinity State.' This means even tiny amounts of dopamine create 'noise' rather than a clear signal. This uncoupling process takes much longer than simply flushing the drug out.
So, you aren't 'broken.' Your brain just accumulated more DeltaFosB or has a stiffer G-Protein adaptation, which requires a longer (but finite) time to reset."
This is the information ı get from gemini
Click to expand...
Who is gemini? And how you have such info about? This is amazing knowledge
 
Trueart2 said:
Wrong. At least in the case of Invega smoking weed actually speeds up the recovery process as it helps remove Invega from the brain.
Click to expand...
We should have scientific data and info about, someone have to take us seriously and make a recovery protocol if is not possibile make an antidote
 
RisperdalConsta50mg said:
We should have scientific data and info about, someone have to take us seriously and make a recovery protocol if is not possibile make an antidote
Click to expand...

There’s no medication that reverse the effects of Antipsychotics currently. If they had the ability to undo what has been done to us through medicine, the antipsychotics would probably have evolved to a point of being even more damaging.

@keepinghope had a protocol. People weren’t taking it serious enough and he warned us many times about people complaining about their situations yet doing nothing. He took down the discord with the information about recovery. I’m not saying he took it down because people were doing too much complaining but he was the only one who made a protocol to follow.

The only thing we can do is take supplements, exercise, and wait.
 
Trueart2 said:
Gemini is AI, don’t trust it too much.
Click to expand...
ChatGPT told me the same, that 12-18 months is the average recovery time, and some people take even 24 months..

I tried with another AI and it gave me basically the same answer.. Idk what to think about, it don’t seem to me that I Will recover in the next 2 months, not even in the next 8 months..
 
Trueart2 said:
Gemini is AI, don’t trust it too much.
Click to expand...
I am sure that no doctor, not even the ones who prescribed this medicine for you, has better technical knowledge than any doctor you may know.Gemini Ai has better technical knowledge than any doctor you will ever meet. I am sure that no doctor, not even the ones who prescribed this medication for you, knows this information.
 
fuqrisperdal said:
I am sure that no doctor, not even the ones who prescribed this medicine for you, has better technical knowledge than any doctor you may know.Gemini Ai has better technical knowledge than any doctor you will ever meet. I am sure that no doctor, not even the ones who prescribed this medication for you, knows this information.
Click to expand...
This match perfectly my own experience, since i spoke even with universital hospital of my country and they acted like monkey about, instead, ChatGPT give me so many info about that when i reached every doctor i was more preparare than them about antipsychotics injections lasting effects, this is a fact and this is why they feared so much internet for information back in time and this is why they will fear AI very soon.
 
I feel so much pain
RisperdalConsta50mg said:
This match perfectly my own experience, since i spoke even with universital hospital of my country and they acted like monkey about, instead, ChatGPT give me so many info about that when i reached every doctor i was more preparare than them about antipsychotics injections lasting effects, this is a fact and this is why they feared so much internet for information back in time and this is why they will fear AI very soon.
Click to expand...
I thought ai was giving you false information?
 
RisperdalConsta50mg said:
This match perfectly my own experience, since i spoke even with universital hospital of my country and they acted like monkey about, instead, ChatGPT give me so many info about that when i reached every doctor i was more preparare than them about antipsychotics injections lasting effects, this is a fact and this is why they feared so much internet for information back in time and this is why they will fear AI very soon.
Click to expand...
There are some sensitive scientists working on antipsychotics, albeit limited, but these damn psychiatrists don't know what kind of medication they're prescribing. They have no news of current studies. If the patient can say "yes" or "no" and breathe, that's enough for them. It's obvious they don't care about the aftermath of the medication. Furthermore, there's also the fact that even if the drug is completely eliminated from the body, it can suppress dopamine production for a long time, preventing it from producing enough. This can lead to overproduction of D2 receptors in the brain, leaving them stuck in their sensitivity. Supplements that increase dopamine production without overdoing it should be taken to convince the brain, "Yes, I'm getting enough dopamine, it's time for downregulation."
 
Status
Not open for further replies.
Top