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2-(3,4-methylenedioxyphenyl)-3-aminocyclopentane.png


PLAYER
2-(3,4-methylenedioxyphenyl)-3-aminocyclopentane
 
1-(4-oxa-1-piperidinyl)-2-phenyl-2-(3,4-methylenedioxyphenyl)-cyclohexane.png


PATTY_SUE
1-(4-oxa-1-piperidinyl)-2-phenyl-2-(3,4-methylenedioxyphenyl)-cyclohexane
 
1-carbomethoxy-1-phenyl-1-(1-(2-phenyl-1-methylethyl)-piperidin-4-yl)-methane.png


NOCIOCILLER (pain killer)
1-carbomethoxy-1-phenyl-1-(1-(2-phenyl-1-methylethyl)-piperidin-4-yl)-methane

by mouth (per os)
 
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1-carbomethoxy-1-(3,4-diacetoxyphenyl)-1-(1-(2-phenyl-1-methylethyl)-piperidin-4-yl)-methane.png


NOCIOEAZER
1-carbomethoxy-1-(3,4-diacetoxyphenyl)-1-(1-(2-phenyl-1-methylethyl)-piperidin-4-yl)-methane

Probably Snortable, IV Able, And Suppository Ready.
 
We discussed this one already before but it is worth revising. It is called an isomer of Pub 105 and shares SAR with cypenamine and DPA-1.
Rectify said:
1-amino-2,2-diphenyl-cyclopentane.png


PEE_WEE
1-amino-2,2-diphenyl-cyclopentane
Click to expand...
You'd need 2,2-Diphenyl-cyclopentanone [15324-42-2] for this.

It's not a new compound: https://pubchem.ncbi.nlm.nih.gov/compound/3044082

"Herman" is not in the database though.

Here is the article that discusses the precursor: https://file1.lookchem.com/doi/2022/8/4/6a4ac52f-f745-440f-b97b-e085d0da5de2.pdf

Easton, N. R., Nelson, S. J. (February 1953). "The Synthesis of 2,2-Diphenylcyclopentanone and Some of its Derivatives". Journal of the American Chemical Society. 75 (3): 640–641. doi:10.1021/ja01099a035.

Kulp, S. S., Fish, V. B., Easton, N. R. (September 1963). "Some Reactions and Derivatives of 2,2-Diphenylcyclopentanone 1a". Journal of Medicinal Chemistry. 6 (5): 516–519. doi:10.1021/jm00341a010.

"(R)-(−)-2,2-DIPHENYLCYCLOPENTANOL". Organic Syntheses. 74: 33. 1997. doi:10.15227/orgsyn.074.0033.

Conley, R. T. (January 1962). "A convenient synthesis of 2,2‐disubstituted‐1‐cyclopentanones". Recueil des Travaux Chimiques des Pays-Bas. 81 (3): 198–201. doi:10.1002/recl.19620810303.

I discovered that an alternative use of the ketone is in the Mannich reaction.

O=C1C(CCC1CN(C)C)(C2=CC=CC=C2)C3=CC=CC=C3

This species does not show in the pubchem database but if you check the Kulp, Fish, Easton article you can see it in there.

A word of caution though is that those who bought Mephtetramine said it was total garbage.
 
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Yes, But What About The *Effects* Of Each Of Those Chemicals?

Also, Is The Following A Makeable Molecule?

1-(1,2-dioxo-cyclooct-3,5,7-triene-5-yl)-2-methylaminopropane.png


LE_PEN_LAZULI
1-(1,2-dioxo-cyclooct-3,5,7-triene-5-yl)-2-methylaminopropane

It's Is A Second (n = 2) Order Aromatic.

H(n) = 4n + 2
H(2) = 8 + 2 = 10 pi electrons
 
1-(2-phenyl-1-methylethyl)-3-carbomethoxy-4-(3,4-methylenedioxyphenyl)-1-aza-cyclohexane.png


RACHEL
1-(2-phenyl-1-methylethyl)-3-carbomethoxy-4-(3,4-methylenedioxyphenyl)-1-aza-cyclohexane
 
1-(2-phenyl-1-methylethyl)-3-carbomethoxy-4-(3,4-diacetoxyphenyl)-1-aza-cyclohexane.png


MELVIN
1-(2-phenyl-1-methylethyl)-3-carbomethoxy-4-(3,4-diacetoxyphenyl)-1-aza-cyclohexane
 
See The Similarities?

1-methyl-4-carboethoxy-4-phenyl-1-aza-cyclohexane.png


DEMEROL (pethidine)
1-methyl-4-carboethoxy-4-phenyl-1-aza-cyclohexane
 
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