Promethazine helps for some people. Others like pseudoephedrine. No reason not to try both together unless other regular medicines contraindicate it.
They do contraindicated eachother. Whilst not dangerous at standard doses, they reduce eachothers efficacy and can have very dysphoric and unpleasant sensations if you're on anything else. The dosage of both is important, in my experience with rhinorrea (I have an oxymetazoline addiction that fucked my nose up GOOD) Pseudoephedrine works best for congestion and promethazine worked better in cases where my nose became irritated from pollen or dirt etc. In higher doses of both the effects become a little unpredictable, not just psychologically. First time I had a weird kidney/back pain, somewhat common with promethazine. My advice would be to stagger your doses. They will be more tolerable that way and will hopefully maximise the efficacy of both.
For opioid withdrawal induced lacrimation, I often use Gabapentin. You could use Pregabalin/Lyrica too, and it would work better, but I am only prescribed the gabapentin. Of course most benzo's will offer some relief too, but I know they aren't as easy to get sometimes (for me, my doctors know I'm an addict and only resort to anything with abuse potential as a last resort) Where I am (Aus) Lyrica is relatively easy to find on the street. I trust them more than street benzos because they are often still in a blister packet and in a box. I know that they can still be interfered with but it's somewhat harder to do than just press a bunch of pills. I don't know if you still need to hear any of this. Clonidine is great for opioid withdrawal. It helps me sleep when I think I'll never sleep again, it's primarily just a blood pressure medication but it's used to ease almost all types of withdrawal. Baclofen is another decent one. It's similair to Phenibut in its effects but acts on the GABAb receptors primarily. Don't take baclofen in extremely high doses because it will make you so sick. It feels like it's shutting down your brain and when I did about 170mg I noticed this weird twitch in my hands. They would flick rotating outwards, and it reminded me of Tardive dyskinesia from long term anti-psychotic exposure, but at least this went away within a couple of days. Be very careful with combining any of these drugs, although they aren't as threatening as the opioids we are used to, a lot of them interact with eachother in ways we don't understand fully. Baclofen, Gabapentin and Pregabalin will all intensely potentiate eachother and in the event of baclofen overdose, we don't know how to treat that effectively. So even with medical intervention, the risk of permanent physical & neurological injury or death is still high.
I hope you have powered through the worst couple of weeks you had ahead of you, and I hope you are safe. If you're still using, I can't and won't tell you that you need to stop, im sure you already know that you should, but i just hope you do everything you can to this as safely as possible. And if you are now clean, i am so fucking proud of you. You dont know me so my opinions should mean fuck all to you, but clean or not its hard just to try and i admire you for just wanting this. It's been 3 years for me with the aid of suboxone, whether or not you have considered that or methadone I don't know. I understand many prefer not to bother, IME full on suboxone withdrawal is more violently uncomfortable than heroin or fentanyl, but I chose it because it's extremely difficult to get high on other opioids whilst having bupe in your system. Where I was at the time I needed that safety met because I didn't/don't trust myself. I'm still on 10mg down from 24mg and the very last step is going to be the trickiest. Because once I'm off it for at least 2 weeks my ability to enjoy opioids fully will be back. I don't know where you are and how your OMP's work there but here it wasn't as hard as I thought to commence the program. It could take a couple of days but you can prepare for that. If you have any questions about that please feel free to DM me, there is also a wealth of knowledge regarding Buprenorphine and Methadone on this site which had got me through the first year. There's a lot I wished i knew about the program when I started and I want to everything I can to offer that advice I wish I had to those who are starting one of the hardest things I've ever had to do. Acting on it or not, wanting something better is the beginning and I know it isn't always an easy conclusion to arrive at, let alone act on.
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