Need Help Definitive List of Comfort Meds for Opiate Detox/ log of fent detox.

[NY2soFlo]

I dont believe what youre doing. I couldnt do that for sure. Support from Spain. I read all thread and Its frightening this fent & fent analogues that you have these days. Its incredible how youre beating this beast. Hands down youre a kind of superman lol. Wish you the best!

I dont have any idea of what fent is so I cant give you any advice. Keep pushing man!!

Thanks man. My story is pretty similar to a lot of people in America. I started on perks than Roxy’s than heroin (gooood NYC dope) and then that transition to fentanyl. And now there’s just so many different analogs and research and chemicals that are so incredibly strong. To give you an idea, I kept my habit these last few years very controlled. Just staying well morning afternoon and night doses. But even with that this stuff is so strong that if I was sick, I could take 20 oxycodone 30s and still be sick that’s how fucking stronger it is. Even other “strong” Fent analogues don’t do it for me. I really fucked myself by choosing a long acting one. It served it purpose in my “functional addiction” days, but we all know those run out. I’m tired of barely making rent, always being broke… I work too hard and make too much to live like that. Plus, I’m 36. I remember telling myself if I made it to 30 I would do anything I had to do to stop. That was six years ago and here I am it’s just gotta be done.


But I also don’t really wanna take any credit because I’ve had some detoxes that were hell-
Granted, I was using much more and probably for longer periods of time. But the benefit of doing it at home is that I can dose my medicine the way I feel fit and include all of the over-the-counter supplements. I really, really think the vitamin C thing is legit. I’m on day five right now of an all out fentanyl detox, and I’m not having fun, but I’m not climbing up the walls hallucinating.

Support from Spain is appreciated! Thank you !

 

[Allylbenzene]

I really, really think the vitamin C thing is legit

Yup I'd say so, have a skim read of this post

 

[NY2soFlo]

For anyone interested:
The (S)-ketamine form used in Spravato is the more dissasociative type that can help reduce tolerances/withdrawls (NMDA antagonist)
The (R)-ketamine form is a DRI (dopamine reuptake inhibitor) like cocaine.
Usually you'll find either pure (S) or a mix of (R)+(S).

The next best OTC thing to ketamine is agmatine. It shares the same antidepressant effects as ketamine but also has extra theraputic effects.

Thanks for the green light on the sun lol. I figured it releases some endorphins as long as it’s not an all day thing.

Unfortunately, I don’t even know the first place to find ketamine. It’s just not the circle that I’m in. my only way would be to get it through a doctor and my doctor is cool as hell, but I’m gonna have to call him in a couple days and ask for a sleep med since the sleeping is starting to become a problem. I don’t wanna hit him with Asking for a Z- drug and ketamine because then he might start looking at me like i’m drug seeking. As it is, I pretty much named everything I wanted for this detox and he just wrote the script for it. I don’t wanna push it.

Plus by the time I actually go see him or talk to him. I’ll probably be mostly through the woods here but that’s also hopeful thinking.

I woke up today starting day five (currently 98 hours since last dose). feeling the best I felt yet. I got about four hours of solid sleep last night. I was expecting the full on withdrawals to start around day three or four as last till day six or seven because this is a longer acting analog, but Whether it’s the vitamin C or the resting or whatever, I feel at least a little bit better today. But I also know, that can change throughout the day pretty radically.

Again, logging onto blue light to see responses on this thread is incredibly, incredibly supportive. I really appreciate everybody’s time and effort and knowledge. There’s not a whole lot of places I can go to actually talk about this with people that understand, so thank you.

 

[NY2soFlo]

Yup I'd say so, have a skim read of

Going to read it now. I’ve read so many studies and so many foreign posts on it I can’t believe how hidden this tool has been the entire time I’ve ever had a detox. It’s literally the only variable that’s different with this detox.

 

[Allylbenzene]

Unfortunately, I don’t even know the first place to find ketamine.

Agmatine has the same key properties as ketamine. Plus more. IF you did try ketamine, i'd opt for VERY low doses...and make sure it's (S)-ketamine.

...but I’m gonna have to call him in a couple days and ask for a sleep med since the sleeping is starting to become a problem.

Agmatine + Theanine should do it. Both knock out adrenaline/stress.
I'd recommend a Magnolia extract too. Standardized to 80%+ honokiol/magnolol. They are pro-GABA cannabinoids.

Magnolol, an active ingredient of the bark of Magnolia officinalis, has been reported to exert potent anti-epileptic effects via the GABA(A) receptor.
The receptor also mediates sleep in humans and animals.
https://pubmed.ncbi.nlm.nih.gov/22771461/

The bark of Magnolia officinalis is used in Asian traditional medicine for the treatment of anxiety, sleeping disorders, and allergic diseases.
We found that the extract and its main bioactive constituents, magnolol and honokiol, can activate cannabinoid (CB) receptors.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4027495/

Surprisingly low-dose Aspirin (acetylsalicylic acid) or plain "sodium salicylate" can support detox & recovery. This originates from White willow bark which is available as an extract.

Aspirin is an antioxidant that protects against lipid peroxidation, but it also stimulates mitochondrial respiration. It can inhibit abnormal cell division, but promote normal cell division. It can facilitate learning, while preventing excitotoxic nerve injury. It reduces clotting, but it can decrease excessive menstrual bleeding. These, and many other strangely beneficial effects of aspirin, strongly suggest that it is acting on very basic biological processes, in a coherent way.
...
Aspirin protects against several kinds of toxicity, including excitotoxicity (glutamate), dopamine toxicity, and oxidative free radical toxicity. Since its effects on the mitochondria are similar to those of thyroid (T3), using both of them might improve brain energy production more than just thyroid. (By activating T3, aspirin can sometimes increase the temperature and pulse rate.) Magnesium, niacinamide, and other nerve protective substances work together.
...
Although the animal studies that showed stomach damage from aspirin often used single doses equivalent to 10 or 100 aspirin tablets, the slight irritation produced by a normal dose of aspirin can be minimized by dissolving the aspirin in water. The stomach develops a tolerance for aspirin over a period of a few days, allowing the dose to be increased if necessary.
...
Vitamin E, like progesterone and aspirin, acts within the cellular regulatory systems, to prevent inflammation and inappropriate excitation. Since uncontrolled excitation causes destructive oxidations, these substances prevent those forms of oxidation.

https://www.functionalps.com/blog/2012/04/22/ray-peat-phd-on-aspirin/

 

[kongoman]

Thanks man. My story is pretty similar to a lot of people in America. I started on perks than Roxy’s than heroin (gooood NYC dope) and then that transition to fentanyl. And now there’s just so many different analogs and research and chemicals that are so incredibly strong. To give you an idea, I kept my habit these last few years very controlled. Just staying well morning afternoon and night doses. But even with that this stuff is so strong that if I was sick, I could take 20 oxycodone 30s and still be sick that’s how fucking stronger it is. Even other “strong” Fent analogues don’t do it for me. I really fucked myself by choosing a long acting one. It served it purpose in my “functional addiction” days, but we all know those run out. I’m tired of barely making rent, always being broke… I work too hard and make too much to live like that. Plus, I’m 36. I remember telling myself if I made it to 30 I would do anything I had to do to stop. That was six years ago and here I am it’s just gotta be done.


But I also don’t really wanna take any credit because I’ve had some detoxes that were hell-
Granted, I was using much more and probably for longer periods of time. But the benefit of doing it at home is that I can dose my medicine the way I feel fit and include all of the over-the-counter supplements. I really, really think the vitamin C thing is legit. I’m on day five right now of an all out fentanyl detox, and I’m not having fun, but I’m not climbing up the walls hallucinating.

Support from Spain is appreciated! Thank you !

So you dont know what drug are you using in your country?? Its really scaring what you have. Dont you have any analithics service?? I mean we have energy control that can analize allmost any drug and for some kinds is free for us living in Catalonia(region of Spain). Its slow, like 2 weeks if you send a letter with a sample but its very useful IMO.

Its difficult for me to understand what kind of people is making/selling this shit that is killing thousands of human beings every year. Its clear that they are beasts, not human beings.

Its really cool if you slept 4 hours straight( I think I cant lol), I told you and I tell you again, youre a kind of superman!!! Keep pushing!!

Youre doing an incredible thing. You have to be proud because few people can do it. I think the most important thing its the psycological part of this. You must have a very good mindset and all the military high level knowledge of people here in BL, I think better than many doctors lol.

Here its 6 pm but you might be awake or close to. Have a good day man!!

 

[NY2soFlo]

Agmatine has the same key properties as ketamine. Plus more. IF you did try ketamine, i'd opt for VERY low doses...and make sure it's (S)-ketamine.


Agmatine + Theanine should do it. Both knock out adrenaline/stress.
I'd recommend a Magnolia extract too. Standardized to 80%+ honokiol/magnolol. They are pro-GABA cannabinoids.




Surprisingly low-dose Aspirin (acetylsalicylic acid) or plain "sodium salicylate" can support detox & recovery. This originates from White willow bark which is available as an extract.

https://www.functionalps.com/blog/2012/04/22/ray-peat-phd-on-aspirin/

Tomorrow I go home (all of 5 mins away) and the agmatine is first on the list, followed by same day Amazon theanine and L phenylalanine. I’m curious to see how it affects me vs tyrosine. 5 days in and the tyrosine ain’t kick in like it did a few days ago.

Ketamine is just a non option for me, so Agmatine is perfect.

And I’ll look into the asprin things.

Still trying to get some input/user experience in black seed oil. I’ve been taking two pills a day a.m. and p.m. they are 200 mg extract pills equivalent to 5% of the active ingredient which seems pretty decent. I don’t know if it’s doing anything, but if somebody told me that it was doing something that would be nice to hear

 

[NY2soFlo]

So you dont know what drug are you using in your country?? Its really scaring what you have. Dont you have any analithics service?? I mean we have energy control that can analize allmost any drug and for some kinds is free for us living in Catalonia(region of Spain). Its slow, like 2 weeks if you send a letter with a sample but its very useful IMO.

Its difficult for me to understand what kind of people is making/selling this shit that is killing thousands of human beings every year. Its clear that they are beasts, not human beings.

Its really cool if you slept 4 hours straight( I think I cant lol), I told you and I tell you again, youre a kind of superman!!! Keep pushing!!

Youre doing an incredible thing. You have to be proud because few people can do it. I think the most important thing its the psycological part of this. You must have a very good mindset and all the military high level knowledge of people here in BL, I think better than many doctors lol.

Here its 6 pm but you might be awake or close to. Have a good day man!!

You are 100% correct it’s a really fucked up situation here. When I lived in New York, it was pretty standard. You would get regular heroin and it was just a matter of its strength. Once fentanyl initially came in it was just the regular fentanyl it hit hard and left you sick three hours later.

Now I’m down in South Florida. It’s a whole different port city. It’s getting its whole different supply of different analogs of fentanyl and I couldn’t for the life of me Tell you what I’m taking. All I know is when I went to the doctor for my detox kit I popped for benzos fentanyl and MDMA, which is scary.

A few years ago, I went into detox and they did a full blood spectrum analysis, and the product I was using was fentanyl, carfentanyl, and then about five other metabolites of different opiates and sprinkled in with that was a couple research grade benzos. I mean really, the people selling it in South Florida have no sense of business. It’s just for a quick buck. In New York it was a business. They understood that Customer is coming back.

America’s drug policy is definitely more conservative than Europe’s, I don’t think anybody would argue that. And if I had an easy way of testing my product, trust me, I would do it. Either way thanks for the support. It’s day five I’m just trying to make one more sunrise and one more sunset.

 

[Allylbenzene]

To improve your sleep quality lower the blue light spectrum on your screen at night. The eyes register blue light as stimulating aka daytime. Phones have that option but apps work better. Twilight for android, fl.ux for PC, idk for iphones.

On black seed oil, yes it's active.

Thymoquinone: From Nigella sativa to a protective pharmacological compound in managing opioid dependence and amphetamine type stimulant issues

Thymoquinone has been reported for its high therapeutic potential in a number of medical conditions, including substance abuse therapy. It also has potential chemical effects mimicking opioids, especially on the mechanisms of opioid dependency and tolerance.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7395189/

 

[4DQSAR]

I can't speak for the US but the BNF guide suggests that a 10% reduction per week should be the maximum reduction to avoid the patient developing AWS,

I SHOULD add that they had to add a new section just for tapentadol in which that same 10% should be used alonw with 'see sawing' i.e. giving people a higher dose for 12 hours a day and a lower dose for the remaining 12 hours, We do not see much tapentadol in the UK - it's a CD so it's tighty controlled and my guess is that a GP given the option of DHC continuous or tapendadol is likely to go for the former. If only because they have a lot of experience with it and know the potential risks,

 

[Allylbenzene]

the BNF guide suggests that a 10% reduction per week should be the maximum reduction to avoid the patient developing AWS,

He took his last dose ~101 hours ago, but he's been using opioid-mimetics and a metabolic stimulant amongst other things. Who knew ascorbic acid had opioid-esque influences.

tapentadol

Interesting, another phenylpropylamine but with dual opioid/NRI effects. It's reminiscent of dimethylaminopivalophenone which is ½ the potency of morphine.

 

[4DQSAR]

Do we KNOW dimethylaminopivalophenone has NRI activity in man? Because I found (both) patents and suspect one reason it was never made into a medicine was the low TI in animal models. While it DOES overlay pethidine in ChemOffice, the metabolism is somwhat different and more importantly, as soon as N-demethylation occur, it doesn't overlay the pethdine metabolite that has NRI activity. Or, rather I should say - the lowest energy conformations do not overlay.

If nothing else, it's been known about for DECADES and yet not one RC vendor has offered it (AFAIK) and given synthesis is ONE step, it would seem quite the obvious one to go for if it was any good. Thay made AP-237 whish is dreadful, so why not this?

Benzanoid opioids aren't really a new idea. Tapentadol is just the ring-open homologue of prolilidine and picenadol. None of which have much to recommend them.

 

[NY2soFlo]

To improve your sleep quality lower the blue light spectrum on your screen at night. The eyes register blue light as stimulating aka daytime. Phones have that option but apps work better. Twilight for android, fl.ux for PC, idk for iphones.

On black seed oil, yes it's active.

Oh I’m already there on the blue light reduction lol. Tv, phone, anything before bed.

And thanks on the BSO info. Any idea on dosing or overdosing? I’m currently taking 200mg extract am and pm. It’s an extract pill equivalent to 5% thyroquinine (idk). If it’s helpful, and I can take more. I want to. I figured Am and PM was a safe bet to start.

 

[NY2soFlo]

I can't speak for the US but the BNF guide suggests that a 10% reduction per week should be the maximum reduction to avoid the patient developing AWS,

I SHOULD add that they had to add a new section just for tapentadol in which that same 10% should be used alonw with 'see sawing' i.e. giving people a higher dose for 12 hours a day and a lower dose for the remaining 12 hours, We do not see much tapentadol in the UK - it's a CD so it's tighty controlled and my guess is that a GP given the option of DHC continuous or tapendadol is likely to go for the former. If only because they have a lot of experience with it and know the potential risks,

You’re going to have to have some patience with me here bc I’m missing out on a lot of the shorthand you’re using. I’m guessing BNF is a British goverment department, and AWS is acute withdrawal symptoms. After that I’m lost.

But, if I do understand your general point correctly, you’re saying that in Britain, they recommend a 10% reduction as in weaning off? Before going into full on WD?

I’ve tried weaning off, but the problem is that every step that you wean off, you end up feeling pretty much for withdrawal symptoms anyway. So out of the last 15 years of experience, i’ve resigned to the idea that I’m just going to do my best to wean down if I can, but pretty much just go cold turkey. I’d rather feel like shit for two weeks then feel like shit for a week every couple weeks as I wean down. I know reducing your dosage is gentler on your body, but I just don’t have a lifestyle that I can be sick every other week

But if I’m not following what you were trying to say, please correct me because I’m here to get any knowledge I can thank you.

 

[NY2soFlo]

He took his last dose ~101 hours ago, but he's been using opioid-mimetics and a metabolic stimulant amongst other things. Who knew ascorbic acid had opioid-esque influences.


Interesting, another phenylpropylamine but with dual opioid/NRI effects. It's reminiscent of dimethylaminopivalophenone which is ½ the potency of morphine.

What are the opioid mimetics Im using? Is that bad? I’m sorry but my brain is currently working at max 35-40% right now. But yes, vitamin C has to be the main variable here. Bc this is the easiest detox I’ve had. And I’ve detoxed from much less usesge, much less time using, and much milder compounds.

I went into this expecting the worst. Four years of nonstop fentanyl use and it’s been at least four or five years from my last detox and I’m well aware the more you do it and the older you get the harder it is. I have to contribute the pleasant surprise to vitamin C. I’m actually planning on cutting all of my comfort meds in half tomorrow. I’m starting to think that’s causing more lack of energy than anything else. When I hit four or five hours after my dose, I start getting energy and if I’m not having symptoms that require those meds, why keep taking them? Tomorrow is day six maybe I’ll just cut everything down and rely on the vitamin C and eating and trying to move.

 

[pnillyg]

Whether your detoxing off 3 months of 5mg Vicodin or 6/7 years if H/fent/something stronger pain is all relative. Sure, if you tried all of these and detoxed, the hard drugs would be worse. But it doesn’t take away an ounce of courage or strength to. Overcome.

thank you for acknowledging that, big ups to you much appreciated.

 

[pnillyg]

You’re going to have to have some patience with me here bc I’m missing out on a lot of the shorthand you’re using. I’m guessing BNF is a British goverment department, and AWS is acute withdrawal symptoms. After that I’m lost.

But, if I do understand your general point correctly, you’re saying that in Britain, they recommend a 10% reduction as in weaning off? Before going into full on WD?

I’ve tried weaning off, but the problem is that every step that you wean off, you end up feeling pretty much for withdrawal symptoms anyway. So out of the last 15 years of experience, i’ve resigned to the idea that I’m just going to do my best to wean down if I can, but pretty much just go cold turkey. I’d rather feel like shit for two weeks and feel like shit for a week every couple weeks as I wean down. I know reducing your dosage is gentler on your body, but I just don’t have a lifestyle that I can be sick every other week

But if I’m not following what you were trying to say, please correct me because I’m here to get any knowledge I can thank you.

right now dealing with the effects of NAC blocking the ketamine not sure exactly why but its completely blunted the effects. i also have heard interesting things about memantine

 

[NY2soFlo]

right now dealing with the effects of NAC blocking the ketamine not sure exactly why but its completely blunted the effects. i also have heard interesting things about memantine

It’s funny that you mentioned NAC. I have a full bottle of it and I just took one 600 mg pill earlier today after doing a minimal amount of research. Granted, I’m not using anything like ketamine, but it did show some promise in relieving detox symptoms.

But if the ketamine is going to help you more, why not just drop the NAC?

 

[pnillyg]

im tapering oxycodone right now it it helped for sure, that being said the ketamine was helping with the taper so it was kind of a weird trade off and if i didn't have ketamine i would definitely use it but since i do i think the ketamine may have more benefits in my current situation as the NAC please correct me if im wrong though! i did drop the NAC but from my research a single dose of NAC can block the effects of ket for up to a week! bummer

 

[NY2soFlo]

im tapering oxycodone right now it it helped for sure, that being said the ketamine was helping with the taper so it was kind of a weird trade off and if i didn't have ketamine i would definitely use it but since i do i think the ketamine may have more benefits in my current situation as the NAC please correct me if im wrong though! i did drop the NAC but from my research a single dose of NAC can block the effects of ket for up to a week! bummer

Outside of weaning off – which I have plenty of experience with I really don’t know much about ketamine or the pharmacological effects of NAC. But just from a common sense point of view if ketamine is helping you fuck the NAC.

Also, there’s been some really great people in this thread. If you take the time to read through it, we have been given really good information about different over-the-counter supplements that are all relatively cheap that can really help with weaning down. Even the vitamin C that I’m taking there’s a lot of literature where besides helping withdrawals, it really helps reducing tolerance and cravings, making it easier to wean down. I would give this full thread a read. . There’s a plethora of information in it. And not much fluff it’s pretty dense with information. lol.