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  • Trip Reports Moderator: Cheshire_Kat | M!$ter-ED

Can you shoot 7-hydroxymitragynine?

I

infamous1k

Greenlighter
Joined
Aug 21, 2025
Messages
5
I was wondering if any of y'all have tried to shoot a 7-oh pill? I'm just curious since in my opinion it is the best opioid there is besides fentanyl that Ive tried and that's anything from codeine,methadone morphine, meperidine etc... to fentanyl to heroin.
 
If you can separate the 7-OH of the pill, so pure 100 %.
Sterile using a micron filter, i hate when they draw my blood.
Childhood trauma, don t shoot it, oral or boof it. [the bud-hole]

Thinking about IV, i look away and need dr/ or better an nurse.
They are just better, male or female don t matter, they shoot well ime.

So i wouldn t risk it, Kratom oral was fine for me, 7-OH is already a beast.
Why try or tempt it ?
 
emkee_reinvented said:
If you can separate the 7-OH of the pill, so pure 100 %.
Sterile using a micron filter, i hate when they draw my blood.
Childhood trauma, don t shoot it, oral or boof it. [the bud-hole]

Thinking about IV, i look away and need dr/ or better an nurse.
They are just better, male or female don t matter, they shoot well ime.

So i wouldn t risk it, Kratom oral was fine for me, 7-OH is already a beast.
Why try or tempt it ?
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Oh I was just wondering. I most likely won't do that.I just thought about it and see if people have done it.
 
It doesn’t dissolve right. I think you need to adjust the ph to get it into solution. But you also need to get a pure powder extract with no impurities which I don’t believe is available. Or you’d have to have a method to clean the 7oh to 100% purity at home. And you have to adjust the ph because 7oh like mitragynine and like the kratom leaves themselves is hydrophobic I believe. So it doesn’t mix readily into water. Tackle that and I think you’d have a solution capable of being iv’d. You’d also be a human guinea pig with no idea of what would happen. Does it cause an incurable abscess every time? Who knows but you’ll be the one to find out. I wouldn’t be that guy. But yeah injected 7oh would probably be awesome.
 
helpingout said:
It doesn’t dissolve right. I think you need to adjust the ph to get it into solution. But you also need to get a pure powder extract with no impurities which I don’t believe is available. Or you’d have to have a method to clean the 7oh to 100% purity at home. And you have to adjust the ph because 7oh like mitragynine and like the kratom leaves themselves is hydrophobic I believe. So it doesn’t mix readily into water. Tackle that and I think you’d have a solution capable of being iv’d. You’d also be a human guinea pig with no idea of what would happen. Does it cause an incurable abscess every time? Who knows but you’ll be the one to find out. I wouldn’t be that guy. But yeah injected 7oh would probably be awesome.
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It would also be like straight up worse than crack and I think people would completely bankrupt themselves and lose everything over and over again.

Ima amazed at how bad my brain thinks it would be.
 
I strongly disagree that 7-OH is the best type of opioid next to fentanyl.

7-OH has it's place indeed in the opiate/opioid field but it is not a drug that can be used daily for chronic pain, chronic pain syndrome, cancer pain, post-op acute pain, and breakthrough pain needs.

Opioids like Oxycodone, Diluadid, Morphine, Methadone, Fentanyl, Suboxone, and Oxymorphone will work for decades for daily long-term treatment without having to increase dosages on a regular basis. 7-OH is the exact opposite.

I am sure many people will disagree with me on this and that is fine with me. My point of view is based on being physically dependent and addicted to Rx opiates/opioids for going on 40 years. I haven't had to increase my Roxicodone 210mg and Methadone 40mg in 13 months & I am doing just fine.

The only way I can get a desired result from Opia 7-OH is to take 480mg in one dosage.
 
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Just DONT. Could a mad chemist figure out a way -- probably. would it be worth it, obviously not or they would have!
You can Smoke 7-OH which means you can get a rush without shooting it -- not sure on the BA but be careful!!

7OH and Fentanyl hardly count as there extreme lack of euphoria.. (Pain I can't speak on -- well much I'm almost over the hill -- they seem to work for a elderly person I know who's Dr wont write -- only uses em for a day or two tops and low dosages)

That second list was the sweet one forsure.

I am actually not sure if I am agreeing or disagreeing with you but either way I recognize you are treating pain which requires a different strategic approach
 
infamous1k said:
I was wondering if any of y'all have tried to shoot a 7-oh pill? I'm just curious since in my opinion it is the best opioid there is besides fentanyl that Ive tried and that's anything from codeine,methadone morphine, meperidine etc... to fentanyl to heroin.
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You peaked my curiosity, so I’m one of those who asked to find out myself. I took a small piece of a 30 mg chewable 7 oh tab (~4mg-5mg). Just to keep it as “safe” as possible. Put it in a spoon with water and a bit of lemon juice. Put my lighter under it, mixed, and cotton filtered 30 units of solution. Slammed it home and instantly that wave came over.

Shorter high, of course, than sublingual ROA. But what a rush.

Never planning on doing it again because I liked it too much. And I don’t need to go down that road again.

IMO, if you like 7 oh be thoughtful and careful.

BTW, I doing small amounts overall as I’m just over a year H free.
 
^Be careful on many levels -- I don't know enough about 7 oh to get too preachy but it doesn't feel like something that 'makes sense' to shoot. All the plant matter and stuff is gone so if you get pure 7 oh -- I mean it is your body.

Shoot responsibly my friend (Doseki's man voice). haha I prolly woulda done it if it were around 15 yrs ago when I was doin my thing so I wont lecture too hard
 
kothen66 said:
You peaked my curiosity, so I’m one of those who asked to find out myself. I took a small piece of a 30 mg chewable 7 oh tab (~4mg-5mg). Just to keep it as “safe” as possible. Put it in a spoon with water and a bit of lemon juice. Put my lighter under it, mixed, and cotton filtered 30 units of solution. Slammed it home and instantly that wave came over.

Shorter high, of course, than sublingual ROA. But what a rush.

Never planning on doing it again because I liked it too much. And I don’t need to go down that road again.

IMO, if you like 7 oh be thoughtful and careful.

BTW, I doing small amounts overall as I’m just over a year H free.
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Wow thx for volunteering as tribute. I do not have the stones to try that even after but an interesting data point. I thought it would not be slammable at all.
 
I've been considering shooting 7 OH all day, but decided to give it a Google first. I'm glad I did. Thank you, kothen66, for the confirmation. You've been more than helpful.
 
helpingout said:
7oh like mitragynine and like the kratom leaves themselves is hydrophobic I believe. So it doesn’t mix readily into water. Tackle that and I think you’d have a solution capable of being iv’d.
Click to expand...

The following carriers have been used to IV fat-soluble drugs: propylene glycol, cyclodextrins, lipid emulsions, liposomes, and alcohols (in the past).

People have injected cannabis and Marinol without special solubilizing, but your success with something like that will obviously vary. Injecting oil into the veins can block blood flow to the lungs, brain, and heart.

Intravenously injecting marijuana
 
Its significantly more soluble in Ethanol than in water if youre willing to IV some vodka… Although Ethanol might pull some other unwanted things with it.

Maybe propylene glycol. If one had some pure isolated 7-OH then making a solution of PG, Water and Polysorbate 80 should yield a good ”stable” solution. I know this is the mix they used in an old rat study testing mitragynine. I assume the same would work for 7-OH.



Also PS80 should be decently safe to IV if youre just planning to do this as a one off…
(Yes Im aware this is a study done using zebra-fish as the model animal to create a human estimate)

”According to the FDA IID database, the maximum daily exposure of PS80 in intravenous injections can reach 4739 mg.”

Although…
”Recent reports have speculated that anaphylaxis and allergic reactions to COVID-19 vaccines could be attributed to PS80”
 
red22 said:
The following carriers have been used to IV fat-soluble drugs: propylene glycol, cyclodextrins, lipid emulsions, liposomes, and alcohols (in the past).

People have injected cannabis and Marinol without special solubilizing, but your success with something like that will obviously vary. Injecting oil into the veins can block blood flow to the lungs, brain, and heart.

Intravenously injecting marijuana
Click to expand...
I remember this one youtube video of a woman being injected IV with THC + CBD and then THC by itself at two separate times and saying the THC + CBD combo gave her euphoria and no paranoia while THC solo was anxiogenic and paranoia inducing.

Tbh her reaction to IV THC + CBD made it look absolutely wonderful as that buttery/milky THC dissolved fat-solution made itself into her veins….
 
TheLightBringer said:
I remember this one youtube video of a woman being injected IV with THC + CBD and then THC by itself at two separate times and saying the THC + CBD combo gave her euphoria and no paranoia while THC solo was anxiogenic and paranoia inducing.

Tbh her reaction to IV THC + CBD made it look absolutely wonderful as that buttery/milky THC dissolved fat-solution made itself into her veins….
Click to expand...

BBC Defends Drug-taking Presenter
 
TheLightBringer said:
I remember reading some reddit post of some person who IVd a fat solution of hasch and said it hit them nearly instantly
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Do you think you can find that post? One time I was looking for a reddit post and an AI agent was able to find it for me. Do you remember what was in that solution?
 
red22 said:
Do you think you can find that post? One time I was looking for a reddit post and an AI agent was able to find it for me. Do you remember what was in that solution?
Click to expand...
Hmm I can search but it was years ago, I think they claimed they just stupidly dissolved it in oil/fat and literally just injected the stuff like that, no sterile precautions at all…
 
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