Need Help Definitive List of Comfort Meds for Opiate Detox/ log of fent detox.

[NY2soFlo]

Creatine is worth adding to your tools. You're already using sodium ascorbate which is mentioned.
Creatine shares similarities with ketamine which is prescribed as a antidepressant.

This is a paper looking at the theraputic potential of 4 naturally present substances (agmatine, creatine, guanosine, ascorbic acid)

https://journals.sagepub.com/doi/10.1177/2470547019858083

Well I’ve got creatine monohydrate for years, I’ve been taking my normal 7.5g dose per day just to keep normalcy and for whatever affects it has on atp production (figured that can’t hurt).

So agmatine separates from my clonidine and other meds/supps? Before? After? Does it matter?

And thank you again.

 

[NY2soFlo]

General update I’m at 62 hours. Tomorrow at 8am is 72 hours (end of 3 days, and begining day 4). Based on the longer acting analogue of Fent I was using, I expect things to be hitting their full on stage.

So far things are manageable. Yes, miserable, but I’ve kicked a dozen times in the last 15 years and this is pretty not horrible compared to some of them. Perhaps it was bc my dose was smaller. But who knows how the fent/car fent I was getting converts to go old fashioned “sick 4 hours later” regular fent.” We shall see.

But I really appreciate the input and support here everyone. It’s the only place I can ask real questions and get real input. And if I wasn’t going through it I’d be doing the same for others.

 

[Allylbenzene]

Well I’ve got creatine monohydrate for years, I’ve been taking my normal 7.5g dose per day just to keep normalcy and for whatever affects it has on atp production (figured that can’t hurt).

So agmatine separates from my clonidine and other meds/supps? Before? After? Does it matter?

And thank you again.

Yes, Agmatine after the meds. You can take ~500mg Agmatine several times a day as you see fit, maybe with the sodium ascorbate.

You could try taking caffeine in two 100mg doses (~2 hours apart). This might give better results than 200mg in one go.
Take it with something sweet to support it's effects (orange juice, honey, fruit, sweetened milk etc).
Caffeine boosts mitochondria which need sugar to function. A massive caffeine dose can be OTT and counterproductive for detox.

The metabolic stimulation from coffee ingestion increases the metabolism, which is very friendly, if the metabolic support is adequate. Metabolic stimulators must be matched with adequate metabolic support, especially adequate blood glucose. The common symptom of feeling anxious or shaky after coffee consumption is from a lack of support, which causes low blood sugar.

Theanine helps by stopping the stress response and supporting drug detox.
Theanine pairs well with caffeine.

To boost ATP these will help:
- vitamin B1
- ribose
- nicotinamide

I’d leave the benzos for the worst of it

I'd agree with this btw, benzos have their own issues. At the very least take the minimum dose of benzos possible, halve the tablet if necessary.

fwiw, this combo is a fairly good equivalent to benzos (and has advantages over benzos):
- theanine
- Magnolia bark extract capsules (something like Swanson, Magnolia bark extract 200mg caps @ 90% honokiol + magnolol)

 

[NY2soFlo]

I'd take Agmatine and Theanine separately from the meds and OTC subs, just to be on the safe side. Agmatine potentiates the effects of many drugs.
Those 2 should be fine with caffeine. You can always redose agmatine or theanine throughout the day as you see fit. Theanine works well as an evening thing too.

What is your pre workout stack?

FYI - please keep in mind that Agmatine shares the same property as clonidine. Agmatine is nowhere near as potent as clonidine though.

Also my preworkout stack is a basic “good” pwo (redcon total war) or (huge supps wrecked)… products with full doses of the good stuff. I also add 2.5 g creatine, 1g agmatine , 2.5g hydro max glycerol.

My intra is Gatorade mix, HBCD (cyclic dextrin- carb), and a simple electrolyte mix (non flavored)..

Going hard in the gym has been my savior in racking up my clean years. Plus I like it. There is no feeling better then lifting heavy and going hard. Closest thing to a high I get. And running just isn’t my thing. I’ll do a little cardio for fat loss or some hiit stuff for my heart. So, of course I’m expecting to loose a good 10-15 lbs during this detox which I’m trying to just not think about.

 

[NY2soFlo]

Yes, Agmatine after the meds. You can take ~500mg Agmatine several times a day as you see fit, maybe with the sodium ascorbate.

You could try taking caffeine in two 100mg doses (~2 hours apart). This might give better results than 200mg in one go.
Take it with something sweet to support it's effects (orange juice, honey, fruit, sweetened milk etc).
Caffeine boosts mitochondria which need sugar to function. A massive caffeine dose can be OTT and counterproductive for detox.


Theanine helps by stopping the stress response and supporting drug detox.
Theanine pairs well with caffeine.

To boost ATP these will help:
- vitamin B1
- ribose
- nicotinamide


I'd agree with this btw, benzos have their own issues. At the very least take the minimum dose of benzos possible, halve the tablet if necessary.

fwiw, this combo is a fairly good equivalent to benzos (and has advantages over benzos):
- theanine
- Magnolia bark extract capsules (something like Swanson, Magnolia bark extract 200mg caps @ 90% honokiol + magnolol)

Ok thanks on the agmatine instructions. And yes, I’ve been sipping 100mg caffeine early in the day, and sipping 100mg in the evening. I take it about an hour after 1g tyrosine. The tyrosine is a godsend in terms of fighting the sapping of energy.

I’ve also read that there is some danger in terms of taking too much, Tyrosine. That your body will quickly equalize what it’s willing to use and that the regular dose will become ineffective. I’m hoping that for a good 7 to 10 days of acute withdrawal that wouldn’t become an issue. After that, I’ll cycle it a couple days on in a couple days off. But it’s extremely helpful. I also have DLPA , which I understand is one step farther along in the conversion process, but for me, it hasn’t proven as effective.


As for the benzos, I take 1 mg Klonopin at around 9 AM, and 1 mg Klonopin at around 9 PM. I never really messed around with benzos before but even for me that’s a baby dose and I only have about 10 of them left. So when I get down to a couple pills, I’ll start splitting them in half and I know myself. I won’t have a problem Slowly factoring those out. I take 5 mg***Valium with my clonidine, hydroxyzine, and tizanidine every six hours. Again, benzo wise, this is nothing for me.

Even with the light experience I have with them I was using pressed sticks and they were extremely strong so I don’t even feel these prescribed benzos, so I’m looking at these doses that I’m taking as me weaning off anyway. I’ve always been overly cautious about my benzo used because I know that’s a hell that I’m not willing to go through.


It’s also worth noting that I’m considering this: my earlier detoxes I was coming in soaking wet at 150 pounds. And I’m taking the same med dosages now, and I’m 230 pounds. So I feel pretty safe taking the same prescribed dosages.

FWIW I also take 200mg test C per week (trt) and .2 mg adex eod. (Not that that has anything to do with anything just to give you a better idea of where I’m at.)

 

[NY2soFlo]

Does anyone have any info or personal experience with:
-L-Tyrosine (in an opiate withdrawal context).. or DLPA
-sunlight? … I’m in south Florida. It’s 95 degrees and humid out and for once I’m not hot or sweating. It makes me want to go sit by the pool in the sun for a couple hours. Mostly just to get out of the house, but I’m wondering if anybody knows anything about the effects of some UV light during this process. I’ve tried searching every possible combination of words on Google via Blue light and via Reddit for forums and I can’t find a damn mention of the effect of UV light while going through withdrawal.

Any input here would be useful. Thank you.

Also: I’m at 80 hours right now. All in all not terrible. I’m wondering if it’s all of the other otc things I’m taking on top of the normal detox meds. Still no Subutex I’m gonna try to do this without it.

I’m not sure if this is the correct forum for it, I don’t wanna hijack my own log, but it would be very interesting to compare different types of fentanyl analogs that are out these days. I know in Florida most of it is garbage. I’m not sure what analogue of fentanyl is, but it’s just stepped on. What I found was extremely long acting. Full withdrawals wouldn’t have started from 24 to 36 hours. It made me think it was cut with methadone or something. But I took a UA and nothing came up other than fentanyl. I’ve done some research on the different analogs, but I just don’t know.

 

[Allylbenzene]

2.5g hydro max glycerol

I had a look what that is, turns out its 65% glycerol + 35% silicon dioxide.
Do you use that in a shake? Have you thought about using pure 100% glycerol? It's more concentrated than HydroMax and probably a lot cheaper. It also avoids ingesting silicon dioxide.

I’ve been sipping 100mg caffeine early in the day, and sipping 100mg in the evening

As long as the evening caffeine doesn't cause issues. You could pair the evening dose with ~500mg theanine for improved sleep quality. It's a big dose but theanine is fairly harmless.

I also have DLPA , which I understand is one step farther along in the conversion process, but for me, it hasn’t proven as effective.

IMO the natural L-form phenylalanine is best. IIRC D-phenylalanine inhibits an enzyme involved in dopamine production. I've only ever used L-phenylalanine.

I take 15 mg Valium with my clonidine, hydroxyzine, and tizanidine every six hours.

Just fyi, agmatine shares the same "anti-adrenaline" property as clonidine and tizanidine. So if you ever increase your agmatine dose or use it more frequently remember it will potentiate those other drugs. Agmatine could be worth using in lower doses (~500mg) more frequently - eg with your sodium ascorbate...or at least once @ AM, once @ PM to benefit from it's anti-addiction/anti-withdrawal effects.
It all depends how you feel about it really, i'm just offering ideas. Agmatine (and theanine) both act as a "buffer" from benzo tolerances, and proactively repair things (neurogenesis via BDNF & GDNF).

I’m expecting to loose a good 10-15 lbs during this detox which I’m trying to just not think about.

I also take 200mg test C per week (trt) and .2 mg adex eod. (Not that that has anything to do with anything just to give you a better idea of where I’m at.)

You might find this post interesting, basically anabolics help by blocking anti-catabolic hormones like cortisol/estrogen.
Less cortisol, less weight loss. Theanine and Agmatine both protect/reduce cortisol (directly and indirectly).

...the "anabolic" effects from T and anabolic steroids are actually the result of their anti-cortisol effects. (cortisol is anti-catabolic)

 

[Allylbenzene]

-L-Tyrosine (in an opiate withdrawal context).. or DLPA

Here's a few quotes on L-tyrosine and L-phenylalanine.
It's possible you feel tyrosine more because some of it gets turned into the stimulant noradrenaline. L-phenylalanine gets turned into L-tyrosine and phenethylamine which has it's own psychoactive effects. Personally I wouldn't use DLPA.

As a more bioavailable analog of Tyrosine, NALT is marketed as a nootropic. However the general consensus is that NALT causes the body to produce lots of dopamine, whereas Tyrosine produces both norepinephrine and dopamine. ... Many sources agree that [NALT] it's not really effective as a nootropic, but is a good antidepressant.

I like L-phenylalanine a lot more than tyrosine. The body turns most of it into L-tryrosine, and some into phenethylamine.
...
L-phenylalanine is many times more pleasant and more potent than L-tryosine. (I'm not talking about the cheaper DL-phenylalanine, which I find unpleasant.)
...
I cannot tolerate the DL-phenylalanine mix at all. It gives me tension headaches. I can only use L-phenylalanine. For me this gives me a nice mild boost of energy and it gives me a mild mood lift. I like it quite a bit. I will never ingest the mixed DL form ever again. The body is not made to handle the D form.

But the effects of L-phenylalanine are better than L-tyrosine. Your body can make L-tyrosine from L-phenylalanine, so it has all the effects of L-tyrosine, plus your body can also make phenethylamine from it. This is why the effects of L-phenylalanine are better than L-tyrosine. It costs a little more, but it’s worth that extra bit.

 

[NY2soFlo]

I had a look what that is, turns out its 65% glycerol + 35% silicon dioxide.
Do you use that in a shake? Have you thought about using pure 100% glycerol? It's more concentrated than HydroMax and probably a lot cheaper. It also avoids ingesting silicon dioxide.


As long as the evening caffeine doesn't cause issues. You could pair the evening dose with ~500mg theanine for improved sleep quality. It's a big dose but theanine is fairly harmless.


IMO the natural L-form phenylalanine is best. IIRC D-phenylalanine inhibits an enzyme involved in dopamine production. I've only ever used L-phenylalanine.


Just fyi, agmatine shares the same "anti-adrenaline" property as clonidine and tizanidine. So if you ever increase your agmatine dose or use it more frequently remember it will potentiate those other drugs. Agmatine could be worth using in lower doses (~500mg) more frequently - eg with your sodium ascorbate...or at least once @ AM, once @ PM to benefit from it's anti-addiction/anti-withdrawal effects.
It all depends how you feel about it really, i'm just offering ideas. Agmatine (and theanine) both act as a "buffer" from benzo tolerances, and proactively repair things (neurogenesis via BDNF & GDNF).



You might find this post interesting, basically anabolics help by blocking anti-catabolic hormones like cortisol/estrogen.
Less cortisol, less weight loss. Theanine and Agmatine both protect/reduce cortisol (directly and indirectly).

I’ve tried all the different forms of glycerol, and the Hydro Max for me just works the best with pumps. There’s also a couple new brands out there in the last year that sell it for even cheaper than you used to be able to get it from the limited brands there were. Hydromax* has lost its Patent I believe so, Now there’s other brand names of the whole 65% strength version.

Right now, my problem is, my Agmatine is at my house and I’m at my girlfriend’s house.( I can get 750 mg angmatine in my pre-workout here but then I’m also taking in caffeine and a bunch of other stimulants that I’m not really up for). My house is only five minutes away, but it’s still a fucking task. And I don’t have any pure thing. I have a nighttime sleep aid that contains 100 mg of GABA and 100 mg of theanine, amongst some other good things. But I don’t think that dose is strong enough?

Maybe I’ll get that agmatine via a scoop of pre-workout earlier in the day. It only has 150 mg of caffeine to go with it. Other than that I think the other ingredients are pretty neutral. But I’m not gonna do that twice, not in the p.m..

Also, it just so happens that I’m very much hit for money at the moment. I get a paycheck Friday and then the following Wednesday and I’ll be back on track especially now that I’m not spending money on the bullshit. But right now there’s just no way I can quickly get theanine to me.

And I have to do some more research into the D vs. L phenylalanine thing you mentioned. I haven’t really ever taken it because Tyrosine has always been far more effective for me.

 

[NY2soFlo]

Here's a few quotes on L-tyrosine and L-phenylalanine.
It's possible you feel tyrosine more because some of it gets turned into the stimulant noradrenaline. L-phenylalanine gets turned into L-tyrosine and phenethylamine which has it's own psychoactive effects. Personally I wouldn't use DLPA.

So first thing this Friday morning I’m ordering l-theanine and L phenylalanine. And I’m gonna make a trip home to get my Agmatine and the second pair of clothes so I don’t have to wash them every day here. Lol.

@Allylbenzene-… I can’t thank you enough for all of your help. I’m not able to look at this detox in a simple way. I have to understand things and I wanna make my own decisions, so I really appreciate all of your time you’re putting into helping me. I’m hoping that this log will be something useful for future detoxes. After all, we’re in a new day and age detoxing from fentanyl and all of its analogs. It’s not like we can follow the detox logs of the old H days and have it be applicable. It’s a whole new beast.

 

[NY2soFlo]

I had a look what that is, turns out its 65% glycerol + 35% silicon dioxide.
Do you use that in a shake? Have you thought about using pure 100% glycerol? It's more concentrated than HydroMax and probably a lot cheaper. It also avoids ingesting silicon dioxide.


As long as the evening caffeine doesn't cause issues. You could pair the evening dose with ~500mg theanine for improved sleep quality. It's a big dose but theanine is fairly harmless.


IMO the natural L-form phenylalanine is best. IIRC D-phenylalanine inhibits an enzyme involved in dopamine production. I've only ever used L-phenylalanine.


Just fyi, agmatine shares the same "anti-adrenaline" property as clonidine and tizanidine. So if you ever increase your agmatine dose or use it more frequently remember it will potentiate those other drugs. Agmatine could be worth using in lower doses (~500mg) more frequently - eg with your sodium ascorbate...or at least once @ AM, once @ PM to benefit from it's anti-addiction/anti-withdrawal effects.
It all depends how you feel about it really, i'm just offering ideas. Agmatine (and theanine) both act as a "buffer" from benzo tolerances, and proactively repair things (neurogenesis via BDNF & GDNF).



You might find this post interesting, basically anabolics help by blocking anti-catabolic hormones like cortisol/estrogen.
Less cortisol, less weight loss. Theanine and Agmatine both protect/reduce cortisol (directly and indirectly).

I also take HMB which a more pure and bioavailable form of leucine, which is the most anabolic/anti-catabolic amino acid. I take it first thing upon waking and immediately after every workout and it’s one of the only supplements I’ve ever taken that I noticed the difference of. Whenever your body start creeping into a catabolic state HMB Will reverse that hard. Worth looking into if you haven’t before. And it’s very cheap.

 

[Allylbenzene]

I’ve tried all the different forms of glycerol, and the Hydro Max for me just works the best with pumps. ... Now there’s other brand names of the whole 65% strength version.

What I was saying is that HydroMax is basically diluting glycerol with super cheap silica (sand) and selling it marked up.

Pure 100% glycerol is sold cheap as vegetable glycerine in most stores, 1g = 1g glycerol.
In contrast, 1g HydroMax = 650mg glycerol.

You'd probably save a lot of money buying it pure instead of the diluted HydroMax stuff, and avoid eating ~850mg sand per dose(!)

 

[NY2soFlo]

What I was saying is that HydroMax is basically diluting glycerol with super cheap silica (sand) and selling it marked up.

Pure 100% glycerol is sold cheap as vegetable glycerine in most stores, 1g = 1g glycerol.
In contrast, 1g HydroMax = 650mg glycerol.

You'd probably save a lot of money buying it pure instead of the diluted HydroMax stuff, and avoid eating ~850mg sand per dose(!)

IIRC the other main form of glycerine is glycerine monostearate… which is cheaper and usually is measured 1:1 glycerin: glycerin. But it’s been a bit since I’ve brushed on it. Just always got crazy pumps from hydromax and products with it. Granted, you’ll need to drink a half gallon of water with it, which comes easy. But really it’s just a cellular super saturater.

Any thoughts on getting some sun during detox? My thermostat is at 75 and I’m freezing (normally 72/73). Sitting outside on the patio and down by the pool felt really good. Granted I can lie in the shade, but keeping a little tan while detoxing doesn’t sounds terrible. Just curious if anyone knows of definite good or bad interactions.

 

[NY2soFlo]

Tomorrow (Thursday 8/22) at 8am marks 96 hours. 4 days from my last “1 bag dose”. I did one bag 8am Sunday so that I could at least be alive for the day. I figured I’d sleep not needing meds, but I was correct next 8am (24 hours) started initial detox. “Limbo” I call it, since we all know how insane full out detox can be.

Currently at 3.5 days. Would a long acting analogue of fent really not fully kick in yet? I figured my day 3-4 id be starting the uphill battle. Hopefully going downhill by day 6-8. Kind of like H but a few days longer, kind of like subs but a few days shorter. Anyone have experience with long acting forms of fent? A type where you’d be good for 18-24 hours. This is is south Florida btw, although it would be anywhere. I will say it’s rare. I pay more then I’d admit for it, but it makes me think it was obv touched less and was def a different analogue.

Tomorrow being primarily day 5, I’m going to do my mid day dose of meds slightly less. 75%_50% less, just to see if my malaise of energy is more the detox or more the meds. I know these meds knock me out.

All in all, for anyone prepping to go through I this, I’d say don’t sleep on the vitamin C (sodium Ascorbate), black seed oil, and passionflower extract. There’s been other really good ideas mentioned here and I plan to get them on Friday. I say this on top of the normal detox comfort prns. I’ve had some horrid detoxes, this sucks, but it’s not horrid!

 

[pnillyg]

36y/o… been through the classic opiate path. Oxy->dope->fent. I’ve successfully completed 4 in patient detox’s and one at home detox. I’ve had clean periods of over a year a few times.

But I’ve been using fent in south Florida for 4 years straight. Granted, I don’t just go balls out and do as much as I can (like I used to)… I stick to a regiment of 4 bags a day to stay well. The type of fent I have I barely feel, but it keeps me well for close to 24 hours. This scares me as I know the detox will likely be more drawn out. Last time using this same fent, I waited 72 hours before Suboxone and STILL went into precips.

SO- my plan is to do a “cold turkey” detox meaning NO subs. I’ve done it before with a standard protocol of comfort meds and I just pushed on. I did it. I can do it again, and this time, I’m further along in life and have SO MUCH more to gain from kicking. I’m ready to live my life.

MY QUESTION IS: (and I’m sure threads exist but I can’t find them)… what would we say is the list of standard comfort meds to get from my doctor? Last time I went in, told him the deal and he literally asked me what I wanted. If I remember correctly it was:

-Clonidine (hot cold flashes, rls, helps with physical discomfort)
-hydroxyzine (antihistamine for yawning, sneezing, and has some anti anxiety action… allegedly)
-Valium (anti anxiety, helps sleep, muscle relaxing)
-Muscle Relaxer (I prefer bacofen, but anything would help
-ondasteron (stops nausea)

I did it with these. Below I’ll list some others that I’ve tried, don’t feel strongly that they are as helpful, but I’d like to hear anyone’s opinion on them:

-pregbalin/gabapentin (never did much for me)
-REAL SLEEP AID (like ambient… not some off label old school anti depressants. Those just don’t do it for me)
-cbd/weed (cbd may have helped before, but weed didn’t actually help much other then giving me a mental break. And maybe appetite stimulating)

And lastly, other supps that I can get otc that may help:
-Delta Sleep Inducing Peptide (helps sleep)
-NAD+ (has some promising initial research to overall recovery post acute, and in lowering acute withdrawal)
-SODIUM ASCORBATE (at high doses, there are LOTS of people saying this was “the” godsend. I’m willing to try it)
-passionflower extract (helps with mood/depression)
-L-Tyrosie/DLPA- (dopamine precursors. This seems like it make be more helpful for PAWS… anyone use during scute?)
-loperamide (obviously helpful)


Anyone with ANY INPUT here is greatly appreciated. I’m aiming to start detox in about 10 days. I work from home during the week, and can take off from my weekend job. I’m in the process of getting my ex gf back, so I have to just do this. Life gets SO good SO quick when you throw all this BS out!!!

Anything I missed? Whether it’s the top catagory- prescribed “must haves”? Any random things that helped them?

Like I said this ain’t my first rodeo, but I’m convinced I can make it manageable with the right meds. And my mindset to quit is stronger than it ever was. To me, clonidine is king. If I had to pick one med, that would be it.

NAC is interesting as well. Ketamine is where it’s at but not sure if that’s the path you want to take. It’s helped me a ton but also came with some addiction and isn’t good for the body in many ways. But for the acute phase it’s incredible. Sublingual troches.

 

[pnillyg]

NAC is interesting as well. Ketamine is where it’s at but not sure if that’s the path you want to take. It’s helped me a ton but also came with some addiction and isn’t good for the body in many ways. But for the acute phase it’s incredible. Sublingual troches.

I’m about to go through the same thing by the way. Doc said I can do Buttans patches, buprenorphine tablets, or sublicade/brixadi or I can taper/ct the oxy which is going but going slow and not a very consistent bath. But I’ve gotten down from 25-30mg a daily to like 12.5-15mg. Also I know that we’re dealing with different monsters here but when you’re like us any form of withdrawal blows IMO. Here with you homie

 

[NY2soFlo]

I’m about to go through the same thing by the way. Doc said I can do Buttans patches, buprenorphine tablets, or sublicade/brixadi or I can taper/ct the oxy which is going but going slow and not a very consistent bath. But I’ve gotten down from 25-30mg a daily to like 12.5-15mg. Also I know that we’re dealing with different monsters here but when you’re like us any form of withdrawal blows IMO. Here with you homie

 

[NY2soFlo]

Whether your detoxing off 3 months of 5mg Vicodin or 6/7 years if H/fent/something stronger pain is all relative. Sure, if you tried all of these and detoxed, the hard drugs would be worse. But it doesn’t take away an ounce of courage or strength to. Overcome.

 

[kongoman]

I dont believe what youre doing. I couldnt do that for sure. Support from Spain. I read all thread and Its frightening this fent & fent analogues that you have these days. Its incredible how youre beating this beast. Hands down youre a kind of superman lol. Wish you the best!

I dont have any idea of what fent is so I cant give you any advice. Keep pushing man!!

 

[Allylbenzene]

Any thoughts on getting some sun during detox? My thermostat is at 75 and I’m freezing (normally 72/73). Sitting outside on the patio and down by the pool felt really good. Granted I can lie in the shade, but keeping a little tan while detoxing doesn’t sounds terrible. Just curious if anyone knows of definite good or bad interactions.

Ketamine is where it’s at but not sure if that’s the path you want to take. It’s helped me a ton but also came with some addiction and isn’t good for the body in many ways. But for the acute phase it’s incredible. Sublingual troches.

For anyone interested:
The (S)-ketamine form used in Spravato is the more dissasociative type that can help reduce tolerances/withdrawls (NMDA antagonist)
The (R)-ketamine form is a DRI (dopamine reuptake inhibitor) like cocaine.
Usually you'll find either pure (S) or a mix of (R)+(S).

The next best OTC thing to ketamine is agmatine. It shares the same antidepressant effects as ketamine but also has extra theraputic effects.