Miscellaneous Most anxiolytic psychedelic drugs

[MindlessBilly]

Nbome are probably the least anxiogenic psychedelics I’ve ever tried. That’s a good answer. Feeling sober with just powerful visuals is nice.

All the other ones have some sense of stress to them even though I did tons of them and have always been fascinated with their effects so I was willing to do them all.

Dissociatives are anxiolytic at times but I don’t count them as psychedelics like this sub forum does

25i-NBOMe i found to be one of the most anxiogenic psychedelics I've ever used totally unenjoyable trips the handful of times I tried it, where as 25c-NBOMe was one of the most euphoric and fascinating psychedelics I've ever used producing some of my most memorable trips.

 

[pupnik]

Each individual seems to be under a different amount of pressure, and since we are all under the same air pressure, the perceived pressure people are seeking relief from (anxiolysis) is what they are carrying from the last few minutes into this moment in time.

All psychedelics are wonderful, but if you present your stressors to the psychedelic state of mind it will ramify and resonated profoundly like anything else.

one must learn to calm the fuck down.

 

[LucidSDreamr]

Every psych I’ve tried has had some rather anxiety inducing moments. I’m of the opinion that throwing booze/benzos/opioids in with any trip is the key to finding a more somatic experience that I enjoy. Mushrooms and Psilacetin after the come-up is over tend to feel very relaxing especially in conjunction with benzos and opioids.

I guess I just prefer to dose higher with my psychs and force the anxiety away with downers. I’m a naturally anxious person though and the older I get the less interested I am in the most intense of psychedelic effects.

I would describe myself exactly like you but I always felt that doing benzos with a wasn’t even worth it that it dampened the experience so much.

Even opioids too….although I definitely usually did opioids with them but would always do it during the come down and only because I’m an opioid addict not because it helped the trip or comedown the way it would help a stimulant comedown.

 

[bigjackaal96]

Yeah, I think that this sub is moreso the "hallucinogen" sub since we also hold onto deliriants, salvinorin, and imo it'd be the best place to talk about synthetic cannabinoids too since they're blatantly psychedelic (or deliriant) for most people. Cannabis having its own is nice, but those aren't people who drink a large amount of Banisteriopsis caapi tea and smoke 1.5-2.5g of dabs like I was frequently doing for a while, as that's a blatantly psychedelic experience that would send your average stoner right into a straightjacket. Imo dissos can be hit or miss for anxiolysis, I was watching Scooby Doo & The Witch's Ghost with this guy once and the ketamine became ketamean, he asked to turn it off because it was too scary then spent about 3 days barely able to move or speak.

You can't even talk about synthetic cannabinoids/GABAergics/Salvia on Reddit & other spaces without them lashing out that their Deliriant psychdelic's. I'm like they do realise too much 5HT1A agonism can produce deliriant effects that common with high dose DMT?.

 

[LucidSDreamr]

You can't even talk about synthetic cannabinoids/GABAergics/Salvia on Reddit & other spaces without them lashing out that their Deliriant psychdelic's. I'm like they do realise too much 5HT1A agonism can produce deliriant effects that common with high dose DMT?.

It’s Reddit bro. Mushrooms are as good for you as veggies be because they are “natural” while 2CB eats holes in your brain because it’s “synthetic”

Your pineal gland releases DMT but onlwh you die;

Every drug except mushrooms and weed are addictive poisons because they aren’t “natural” except ketamine. Ketamine is totally wholesome and good for you ( because the adds in my Instagram feed say so).

Methadone stays in your bones forever.

The brown specs in ecstasy pills are specs of heroin laced into the pill making it with 10X more money but the prices stays the same as non heroin pills

Weed smoke doesn’t cause cancer and is actually good for your lungs.

"the sacklerss are the sole reason the entire country is flooded with cartel fentanyl/tranq"

….yea that’s Reddit drugs posters. Kids that started weed a year ago and have done 3 mushroom trips. and have an iq of 40. That's why I love about BL. Everyone here seems to be pretty knowledgable about drugs and most above average intelligence in general.

 

[bigjackaal96]

It’s Reddit bro. Mushrooms are as good for you as veggies be because they are “natural” while 2CB eats holes in your brain because it’s “synthetic”

Your pineal gland releases DMT but onlwh you die;

Every drug except mushrooms and weed are addictive poisons because they aren’t “natural” except ketamine. Ketamine is totally wholesome and good for you ( because the adds in my Instagram feed say so).

Methadone stays in your bones forever.

The brown specs in ecstasy pills are specs of heroin laced into the pill making it with 10X more money but the prices stays the same as non heroin pills

Weed smoke doesn’t cause cancer and is actually good for your lungs.

Ketamine is. Totally safe and good for you that why it’s advertised on Instagram.

….yea that’s Reddit drugs posters. Kids that started weed a year ago and have done 3 mushroom trips.

It funny when there the 12,000th fuck Alcohol thread Is just 16 ~ 24 year olds downing about 450ml of Vodka then acting shocked when they either start tripping or are severely hungover getting spanked for shaving the fur of their cat.

 

[LucidSDreamr]

It funny when there the 12,000th fuck Alcohol thread Is just 16 ~ 24 year olds downing about 450ml of Vodka then acting shocked when they either start tripping or are severely hungover getting spanked for shaving the fur of their cat.

It’s just the most misinformed group of little 20 year old know it all cucks on Reddit drug forums. Opiates apparently have no medical use at all, don’t work for what they’re fda approved for and are “poison” and all doctors that prescribe them and all pharmaceutical companies (that make anything not just opioids) should go to prison.

Adderall and vaping 23 7 are actually good for you. They help the ADHD that about 98% of the population has, nobody just happens to like amphetamines.

Smoking a half ounce of weed per day is good for your lungs and prevents cancers and is good for your cognitive function. MDMA has zero deleterious cognitive effects and is good for you.

They are sick delusional little immature cucks believeing their own insane lies to justify their addiction.

Someone posted a peer reviewed study in r/science from like some top medical research journal. A meta analysis of tens of thousands of patients proving that THC (smoked or edible) increases one’s risk of stroke or heart attack by like 8X. The little 20 year old drug PhDs all lost their shit and couldn’t cope with those results. It was amusing. “But but but I smoke everyday and run and am fine, therefore the study is bullshit ”

The level of cope.


I can’t even view those subs they are all blocked.

 

[bigjackaal96]

Someone posted a peer reviewed study in r/science from like some top medical research journal. A meta analysis of tens of thousands of patients proving that THC (smoked or edible) increases one’s risk of stroke or heart attack by like 8X. The little 20 year old drug PhDs all lost their shit and couldn’t cope with those results. It was amusing. “But but but I smoke everyday and run and am fine, therefore the study is bullshit ”

The level of cope.

They got super mad when told by data that Weed becomes a Deliriant at strong doses because a CB1 partial agonist, While Nutmeg Is a eCBRI & synthetic cannabinoids are CB1 full agonists. All Atypical Deliriants are very trippy even Alcohol can feel like a euphoric mix of Shrooms & DPH, I can hear music within white noise when drunk.

 

[bigjackaal96]

Imo dissos can be hit or miss for anxiolysis, I was watching Scooby Doo & The Witch's Ghost with this guy once and the ketamine became ketamean, he asked to turn it off because it was too scary then spent about 3 days barely able to move or speak.

That because the brain can switch to Norepinephrine as a new fear centre that works no different to what NMDA agonism did. Paranoia Is basically when It works too well either from It being overactive or NE flooding senitive receptors.

But even If the Disso filled or psychotic brain Is very low with NMDA, They can still run away If they see a lion but won't act like a hot mess.

 

[emkee_reinvented]

Each individual seems to be under a different amount of pressure, and since we are all under the same air pressure, the perceived pressure people are seeking relief from (anxiolysis) is what they are carrying from the last few minutes into this moment in time.

Still wonder about that one. As a kid, and under certain age in general.
Anxiety is normal, a kid you can scare to death by softly monotone saying "Boeh".
Like a cat can on Cucumber s. During ageing i lost most, if not all form off anxiety.

Dentist s, taking blood, personal life treats. No anxiety. I am and certainly have been under high pressure. Way to long and totally unnecessary, so while i carry this all the time. My opposite of anxiety grew bigger and bigger. I relate this to my ageing.

Curious what one would be carrying, my pack being loaded,
that causes anxiety or anxiolysis ?

All psychedelics are wonderful, but if you present your stressors to the psychedelic state of mind it will ramify and resonated profoundly like anything else.

So my state of mind, i am assuming stressors influence it,
is more or less response-able for the trip following.
Or is presenting stressors during it what to me sound as unpleasant trip.

"it will ramify and resonated profoundly like anything else" sound s unpleasant.
But that s my interpretation.

one must learn to calm the fuck down.

This would explain how i react to 1-p-LSD. And my recent retro experience,
with 5-Meo-DIPT, now vs when i was younger.
The last one the 1-st rc ever bought along with aMT.
The effects felt so bitter, stashed em 32 years.

Around when the RC scene moved from UK to Europe.
i started trying Lysergic s. And while fixated on MDMA,
look-a-likes. It was pretty quickly clear my mind made a U-turn,

LSD became favourite, as it is so relaxing and gentle.
Great thought s come up, and all is love.
Even 5 Meo-DIPT and 2C-E have maybe a bit lesser.

Serotonin releasing thing s totally lost their thing.
Only bk-MDMA would make a chance atm entering me.
But for psychedelic s, Lysergic s, all were perfectly ant-anxiety.
Could advice MIPLA [or the 1C-p- version] cause its super relaxed.
Or ALD-52 because it shines. But till now all do it.

My guess its age, life path and my mindset did it.
Anyone else witness this ? Its not like i take it weekly.
Pure on intuition, its not tolerance. My reaction mentally,
to Serotinergic s changed to. I find em annoying now.

Way less relaxing then Lysergic s, so they cause what someone
susceptible for it would call anxiety like symptoms.

 

[pupnik]

1p-lsd is a beautiful thing as is lsd,
not exactly anxiolytic, but they don't make me nervous.
under more than 50 ug dosage, I need very comfortable clothing and environment as I am easily confused by anything complex like a keyboard.

@emkee_reinvented I am not sure what you mean in the previous post, maybe you were using a phone interface and selected shortened words or slang that I am too old to comprehend.

 

[emkee_reinvented]

1p-lsd is a beautiful thing as is lsd,
not exactly anxiolytic, but they don't make me nervous.
under more than 50 ug dosage, I need very comfortable clothing and environment as I am easily confused by anything complex like a keyboard.

@emkee_reinvented I am not sure what you mean in the previous post, maybe you were using a phone interface and selected shortened words or slang that I am too old to comprehend.

Older then me if i am correct, but by a long shot ? i am 50 +
Imo age changed the whole way i feel drug s.
On LSD i am already in what i think will be comfortable.
The set-up is essential, as once it works i am doing nothing,
like cleaning or tidying. i become a puddle of joy and amazement.

Since getting older, breaking it down to the core.
LSD is now as MDMA used to be, which isn t about the effects.
They differ to much, but MDMA drains me while,
during i am bothered by its [side] effect s.
Not totally at ease, like it used to be when young.

While on Lysergic s, but as i found out:
Also Tryptamines and Phenethylamines, to a lesser agree.
My body/ mind no longer find hard to deal with.
No mindfuck or bad trip s.
They relax me and feel very Euphoric,
especially Lysergic s. LSD is un-avaiable to me.

And weird enough not Em-pathogen s,
they are more the 'why did i take it in the 1-st place'
type a drug. Last time i took 5-MAPB.

 

[pupnik]

right, I'm 73 now
agree LSD or 1plsd is very reliable. if I do more than 50 mics I am also a puddle
I loved speed in my 20's and coke in my late 40's and only had speed once later on - loved it but wont go out of my way for it.
I think at lower doses, speedy drugs including mdma can be enjoyable like coffee, even when older, but they push the heart too much when abused.

 

[4DQSAR]

If one is considering the 5HT2a receptor, it's ANTAGONISTS that seem to posess anxiolytic properties.

It's not automatic that agonists will inherently produce anxiety but it more likely that an agent that releases serotonin (but not dopamine) will be anxiolytic. The problem I have noted is that often compounds that have both 5HT2a affinity and are selective serotonin releasers also tend to have 5HT2b affinity - which can be a bad thing.

 

[SotPoker1012]

Interesting to hear that novel psychedelics are perhaps being explored clinically. I'd certainly like to know more about that. Has anything been published yet? Or was it just shared at the conference?

I will add that to the extent that 5-HT2B activation enhances natural serotonin release, it's likely that such activation may also have anxiolytic consequences that counter (to some extent) the effects of 5-HT2A activation. At the same time, many if not most psychedelics have affinity at adrenergic receptors (particularly alpha adrenergic) as well, where they should induce either stimulate or inhibit adrenergic activity.

When I experimented with salvia, I never experienced any anxiety. I've had a variety of doses and a variety of "tiers" of experience. A first tier experience is just kind of stoning. A second tier experience is like taking a lung-full N2O, except a lot more "twisted". Basically, dimensionality begins to break down and one witnesses the deformation of reality including oneself. A third tier experience is rather like dreaming vividly. By comparison, serotonergic psychedelics can definitely make me feel anxious, but some are a lot worse than others. I sometimes have to "work through the experience" to avoid getting stuck in a bad anxious place.

Salvia induces a state of contentedness that can be quite anxiolytic for me. If you have no idea what you're doing, I could see how it could be scary, but ultimately people should research whatever they're taking anyway. I often seek out that "first tier", especially when going through WDs as in addition to anxiety relief, it works wonders for restless legs.

 

[pupnik]

Salvia induces a state of contentedness that can be quite anxiolytic for me. If you have no idea what you're doing, I could see how it could be scary, but ultimately people should research whatever they're taking anyway. I often seek out that "first tier", especially when going through WDs as in addition to anxiety relief, it works wonders for restless legs.

I get this if I dose it correctly, "contentedness" definitely applies. also feels healthy - splendid.

 

[SotPoker1012]

I get this if I dose it correctly, "contentedness" definitely applies. also feels healthy - splendid.

I've found it is easier to get to this state if you chew raw salvia leaves, though a few flakes of 10x in my weed can do it too. Weed can sometimes make me more anxious and the salvia counters that.