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Opioids Hydromorphone (Dilaudid)

But how’s the euphoria factor, I like to fine tune my brain like a precision instrument to get it just right it’s like it’s the most over sensitive thermostat that really should be replaced because it’s so finicky , sadly This central nervous system is all I have to work with
 
But how’s the euphoria factor, I like to fine tune my brain like a precision instrument to get it just right it’s like it’s the most over sensitive thermostat that really should be replaced because it’s so finicky , sadly This central nervous system is all I have to work with

That's homeostasis for you.

Ff you alter your brain chemistry with drugs, you brain will eventally adjust putting you back exactly where you strated from... but sometimes with the addition of NEEDING said drug to feel 'normal'.

That's why my mantra has always been 'drugs can be useful servents, but make terrible masters'.
 
Yeah, ain’t it great tho when they switch it up and let you call the shots being the wonderful subservient servants they can but make no mistake they call the shots those useful servants are experts and making you believe that you are their master but in reality it’s reversed
 
IV Dilaudid was my drug of choice. I fell in love with the rush. I can't imagine having such a high tolerance that IV'ing 16 8's would provide nothing, not even a rush. Hell I can't even imagine IV'ing 16 8's!
I wish I could be of more help. I just read your post and all I could think to say was "WOW".
 
IV Dilaudid was my drug of choice. I fell in love with the rush. I can't imagine having such a high tolerance that IV'ing 16 8's would provide nothing, not even a rush. Hell I can't even imagine IV'ing 16 8's!
I wish I could be of more help. I just read your post and all I could think to say was "WOW".

IV dilly was also my doc for awile. At my worst i was shooting 3 18mg hydromorph contins at a time. But even then i would still feel a 8mg dilly if i was sick especially.
 
IV dilly was also my doc for awile. At my worst i was shooting 3 18mg hydromorph contins at a time. But even then i would still feel a 8mg dilly if i was sick especially.
The thing I hated was how relatively short the high was. It would wear off after 4-6 hours. Yet, you couldn't use as soon as the high starts to wear off. If you wanted to experience the full rush again, you had to wait 12+ hours.
 
I had a script for 30 dilaudid 8s per day at one point. It kept me using fetty though so unfortunately I had to detox myself and stopped going to the dr. The younger me would have loved that prescription but it was a double edged sword.
 
I had a script for 30 dilaudid 8s per day at one point. It kept me using fetty though so unfortunately I had to detox myself and stopped going to the dr. The younger me would have loved that prescription but it was a double edged sword.

Just out of interest, in Canada are they now prescribing injectable forumulation as we do in the UK (on a small basis, I admit).

Because handing a bunch of pills to somone who knows hydromorphone is only about 20% biavailable in man isn't what you might call a well thought out plan. I note that an 8mg injectable format is available.
 
Just out of interest, in Canada are they now prescribing injectable forumulation as we do in the UK (on a small basis, I admit).

Because handing a bunch of pills to somone who knows hydromorphone is only about 20% biavailable in man isn't what you might call a well thought out plan. I note that an 8mg injectable format is available.
Some people were getting the boxes of vials as well, yes. But it’s a weak solution and they ended up having to cook more pills into it anyways . It was like 8mg/mL or something like that. Maybe 10mg tops
 
I have tried everything. All the weird RC's, meth coke and H(IV) E, LSD, shrooms all the pharm opies. The 2 I have not tried are oxymorphone and hydromorphone, they are the 2 that I am absolutely dying to get my hands on. I believe they are pretty much useless unless your planning to IV them, a lot of people hear hydrmorphone is beeter than H, the are totally let down when they try it but they are snorting or taking them orally. They are only better than H if your IV'ing them.

Id also love to try flunitrazepam, Mizazolam IV, Qualuudes, proper opium and a few of the other more bizarre RC's but hydros and oxymorphone are the ones that I have to try before my times up, the others are just potentially interesting and are the main ones that would be ticked off my list and sound fun but ive gotten rushes from coke and meth and I dont know if what H and morphine give you youd call a rush but from what i hear hydromorphone gives you a true rush and im very curious to feel the rush of an opioid.

Hopefully I am lucky enough to experience that in my life.
 
Knoll Pharmaceuticals (sp?) synthasized a more potent, highly water soluble opioid Hydromorphone under the trade name Dilaudid (which is so popular in name, it often displaces HM lol)

Gotta freaking LOVE those German chemists back in the early 1900’s ….Morphine Sulphate, although the “Gold Standard “ and the staple opioid narcotic analgesic ……its slightly outdated dare I say (1800’s +)

Hydromorphone (Dilaudid)
Diacetylmorphine (Heroin / Diamorphine)
Oxycodone (Eukadol) HANDS DOWN most Euphoric pleasurable potent as f@ck opioid analgesic.
Methadone (Dolophine) super potent, super long half-life 24h+, also slightly euphoric
Demerol (Pethidine) (sp?) interesting IV speedball lol, an Mu-Opioid Agonist + DAT & NET reuptake inhibitor

Interesting….there are several analogs to Diacetylmorphine (Heroin) which are MORE potent, faster & harder hitting, and much longer lasting…..like the Dilaudid form of Diamorphine lol

There are HUNDREDS if not THOUSANDS of very strong useful opioid narcotic compounds, unfortunately restricted after the Harrison’s Narcotic Tax , and world wide restrictions of these super potent substances

Fentanyl & Carfentanyl are over hyped garbage IMHO……Fentanyl is used by China as chemical warfare against the US and Canada ….B.C. Cananda is Drug Ravaged Sooooooo bad, they give 100% pure pharmaceutical Hydromorphone injectables + Dilaudid 8mg shields (100,000’s ++++) and injectable Diamorphine (Heroin)

Safe supply and free pharmaceutical compounds …..Carfentanyl is used to dart elephants & rhinos so the vets can work, then Narcan to reverse the sedation lol, my lord. Commie China sending evil Chemical warfare

Dilaudid (Hydromorphone) is a Tier 1 Opioid…….Extremely respected and highly coveted. Back in the 30’s + they came in hypodermic tablets …..can take orally or dissolve in water and inject

Sandoz Pharmaceuticals Canada
Hydromorphone HP FORTE / 1,000 mg in a tiny 10ml glass vial
100mg / per 1ml syringe EASILY the best vial you could ever acquire ….Id love 500 vials from a new production run, and pure API compounding powder of Hydromorphone HCL, , Methadone API powder, Oxycodone API compounding powder …

..then the dopaminergic stimulants (Absolutely Essential)
Amphetamines mixed salts
D-Amphetamine
D-Desoxyephedrine (Desoxyn / Methedrine)
Methylphenidate (Ritalin)
Phenmetrazine (Preludin)
Cocaine HCL crystals (25 gram jars)

….oral Oxycodone and oral Methylphenidate (Ritalin) were the only 2 drugs to EVER give me overwhelming powerful Euphoric bliss, both compounds nearly identical in the profound inner happiness, content, security, outgoing confident …….inner warmth & dopaminergic / endorphins pure euphoric energy and pleasure……ultimate antidepressant and robust mood-boosting properties

Euphoric Opioid
Dopaminergic stimulant
Valium & Xanax
Pregabalin (Lyrica)
Ethanol - Gin 2.oz cocktail + premium cigarettes

Probably the ultimate oral Brompton Cocktail 🍸 I take nearly daily…..for 10-15 years
 
No methadone
In the state of Utah the approved method of capital punishment is 500mg IM injection of Hydromorphone (Dilaudid)

The pharmaceutical company whom supplies the glass bottle of 500mg of Hydromorphone is trying to pull out of the contract due to the association with their product used to kill the condemned

An opioid naive individual Hydromorphone 10mg injection is POWERFUL AS FUCK

Hydromorphone 50mg would be fatal without medical intervention

NOW......imagine 500mg of pure Hydromorphone (more potent than Diacetylmorphine/Heroin)

A MASSIVE Hot dose of Dilaudid.....and that's a wrap
 
I've never done hydromorphone sadly. That's the only drug only list of to do's really. Only opiates anyway aside from pharma fentanyl/hydromorphone/oxymorphone.
 
I have tried everything.

I can only estimate having tasted around 1000 compounds,most long,long ago.

I've never found one I prefer to warmth, shelter, security and a bit of savings.

I strongly suggest that as Shulgin hints at. The best experiences are rarely a drug in.isolation.

If you go back and look at the doses of opioids prescribed from the mid-1950s until the mid-1990s, patient's EMOTIONAL responses were used as evidence to how good an opioid was.

I've mentioned this elsewhere but my hypothesis is that the dynamic binding/unbinding and mean receptor occupancy may well predict how 'euphoric' an opioid is. In conjunction with then ADME all drugs are subject to.

More recently I've noted unusual usage patterns among people who 'like' tapentadol and tianeptine (both low affinity superagonists) and some of the nitazenes because in spite of long theoretical occupancy, at least some seem to internalize receptors FAST which sujectively might be similar to the binding-unbinding cycle.

As a rule-of-thumb, more than an order of magnitude more potent than M is a disaster waiting to happen. Even then, formulations that provoke complience should be considered.

Oh, depending on just how much you enjoy nerding out to extremely misleading promotional experience, it's quite the eye-opener.

NOT direct lies but a press release noting 'very high oral bioavailability' and reading a reference giving 20% is WAY off (in my opinion). Infact the stuff in question is now hardly ever used, so unpredictable.

Last year a thread mentioned it and the time-served British users fessed up. Luckily, THEY couldn't get them so I just asked 'Do you know anyone who survived it'. Nobody had.

But let me set the scene, it's a rough pub where stuff is bought and sold. A connect DOESN'T leaving someone with a 3-bag habit with ONE. So in spite of warnings they use a pin and who is found dead onthe floor an hour later.

I suspect the (very) rapid onset compared with eating pills was too much.

BUT this isn't novel or even new and not one where even users will ALWAYS say 'just eat one'.
 
Fentanyl & Carfentanyl are over hyped garbage IMHO……Fentanyl is used by China as chemical warfare against the US and Canada ….B.C. Cananda is Drug Ravaged Sooooooo bad, they give 100% pure pharmaceutical Hydromorphone injectables + Dilaudid 8mg shields (100,000’s ++++) and injectable Diamorphine (Heroin)

Safe supply and free pharmaceutical compounds …..Carfentanyl is used to dart elephants & rhinos so the vets can work, then Narcan to reverse the sedation lol, my lord. Commie China sending evil Chemical warfare
See here is the either satire or FDA approval is what EMA as most of the world eventually follows.
Now how can these two governments follow up on the sent drugs or receive it, or someone must have order it.
I mean if they won in that simple staightforward warfare tactic than, well what does it say about us you.
Blame is on others I guess always. Responsibility of approved Fent than like Iphone designed in Cali assembled in China or produced while Afganistan is free from people that could make business with best opioids from poppy fields instead of testing militry equipment to catch a man that is war criminal with burner phone who is if it is or was suld be considered and left alive so you can learn how to ide surface to air missile in a goat.

God Helps Us and somehow I think he is like why so you could turn Switzerlands Zürich or Basel into a Baghdad.

Fentanyl as Oxycodone are probably the most fucked up thing.

You know whenever you reverse things come from behind you.
 
The 2 I have not tried are oxymorphone and hydromorphone, they are the 2 that I am absolutely dying to get my hands on. I believe they are pretty much useless unless your planning to IV them
Oxymorphone is powerful as fuck when you snort it. I almost ODed on it multiple times when the old school ERs were still common. Even with my massive tolerace one pill would last me several days sometimes if I wasn't sharing.

Hydromorphone is a bit underwelming through all routes I tried (basically everything but IV). I was going to attempt to IV it once because I'd heared about the awesome rush. But I had a friend who IVed most everything and I watched him shoot one. When I saw his face I knew poppying my IV cherry was a horrible idea. So I just traded them to people that were already using the needle in return for opioids that weren't a waste when snorted or taken orally.

Oxymorphone is probably the one opioid I've tried that I prefer to morphine. I fucking love morphine.
 
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