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Whats the best drug combo of All time ?

just a coker 01 said:
Only advice i can give is stick with oxygen and water, becuase anything else can be worse than weird, it can be seriously fucked up and fuck your life up, many people have died, ended up in the nut house, hospital or prison due to drink and drugs, it can 99.99% of the time be dangerous not weired, i have been in hosptat, and psychiatric units and arrested, many people have and worse, best idea is to speak to a seasoned vetran of substances use and abuse and they would explain that there is a dark side to drugs and the desire to tinker with your own mind.
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GIF by South Park
 
just a coker 01 said:
Looks like someone is saying im a bad person again ! Even when i say theres negative to positives, 🙄
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I'm just teasing try not to take the South Park meme too literally. I'm sure you're a lovely person :)

I can't say I'm a fan of the Nancy Reagan approach to harm reduction though (don't do drugs, just say no, etc) considering all the good it did in the 80s and 90s but you're quite right that the only way to completely mitigate the risks of using a drug is to simply not use it. That's harm reduction 101.

Of course, just because you tell someone not to dabble doesn't mean they're going to listen which is why making clear and unbiased drug information available to everyone is so important. It's funny you you should mention water, the untimely fate of Leah Betts in the mid-90s is a great example of how promoting abstinence over safe (as possible) use simply does not work and can paradoxically lead to further harm.

Anyway, all intended in good spirits friend.
 
marcoman said:
1984 in the hospital. Demerol and valium IV. Floating on clouds, no body, just my spirit/soul. Every 6 hours for 2 weeks. I don't even know if they still use Demerol anymore.
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I've not heard of Demerol being used in hospitals or prescribed, but maybe it's just exceptionally rare. How would you compare it to other opioids, experientially?
 
Shinji Ikari said:
I'm just teasing try not to take the South Park meme too literally. I'm sure you're a lovely person :)

I can't say I'm a fan of the Nancy Reagan approach to harm reduction though (don't do drugs, just say no, etc) considering all the good it did in the 80s and 90s but you're quite right that the only way to completely mitigate the risks of using a drug is to simply not use it. That's harm reduction 101.

Of course, just because you tell someone not to dabble doesn't mean they're going to listen which is why making clear and unbiased drug information available to everyone is so important. It's funny you you should mention water, the untimely fate of Leah Betts in the mid-90s is a great example of how promoting abstinence over safe (as possible) use simply does not work and can paradoxically lead to further harm.

Anyway, all intended in good spirits friend.
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agree her (regan) approach wasnt the most educated citation! In fact when she said it i said no to her order!
 
foodcrisis said:
can't imagine coke and alcohol being something i like..
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LucidSDreamr said:
it actually makes a new drug by the alcohol and cocaine reacting together in your body. Cocaethylene, which is stronger/better than cocaine.
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LucidSDreamer is correct.

Cocaethylene is stronger and much more euphoric than cocaine alone. And it can be very addictive, very quickly.

In 1987 I was drinking heavily and doing IV cocaine almost daily for about 6 months. That combo took me down harder & faster than any other drug or drug combo. I lost everything and damn near died.

Use extreme caution!
 
LucidSDreamr said:
it actually makes a new drug by the alcohol and cocaine reacting together in your body. Cocaethylene, which is stronger/better than cocaine.

What would be interesting is if someone made pure cocaethylene so you could do it by itself without being drunk.
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i hear everyone say this, but from what i under stand it's more toxic. not sure if i'm wording that correct scientifically... like a ton of stuff will turn toxic when taken enough, but i hear it's not the healthiest combo.... to each their own though.
 
Yay, thats why i like to mix coaciane and a fairly moderate amount of alcahol, but yup trigger warning it is toxic but so was a few other relationships, fuck them and ill stick to my personal booze and cocaine , less toxic than the few sourfaced fuckers i knew😎
 
jasperkent said:
LucidSDreamer is correct.

Cocaethylene is stronger and much more euphoric than cocaine alone. And it can be very addictive, very quickly.

In 1987 I was drinking heavily and doing IV cocaine almost daily for about 6 months. That combo took me down harder & faster than any other drug or drug combo. I lost everything and damn near died.

Use extreme caution!
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I deny/100% doubt ill ever iv or skin pop., but even just sniffing lines or a few pipes with liquor,, caution i belive is a neccesartity
 
jasperkent said:
LucidSDreamer is correct.

Cocaethylene is stronger and much more euphoric than cocaine alone. And it can be very addictive, very quickly.

In 1987 I was drinking heavily and doing IV cocaine almost daily for about 6 months. That combo took me down harder & faster than any other drug or drug combo. I lost everything and damn near died.

Use extreme caution!
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I deny/100% doubt ill ever iv or skin pop., but even just sniffing lines or a few pipes with liquor,, caution i belive is a neccesarty
 
Dextro .45 said:
Easy…..the legendary…..the infamous….the one & only…. Brompton Cocktail 🍸

Invented/concocted in the 1890’s in the United Kingdom’s Royal Brompton Hospital for terminally ill patients to make them comfortable, ease their suffering & pain, while having the patient alert and social/talkative, and yes, even euphoric

Original Brompton Cocktail formula : …..essentially an oral Speedball

Diacetylmorphine (Heroin)
Cocaine HCL
Chloroform
Cannabis Indica
Ethanol (mostly Gin)


I have been using a hybrid Brompton Cocktail for many years for chronic pain…..the most essential components are absolutely staple. Period. A potent mu-opioid agonist, a dopaminergic stimulant, a rapid acting benzodiazepine with robust anxiolytic & muscle relaxant properties, plus gabapentinoids and ethanol ….my custom cocktail

Methadone 100-125mg
Methylphenidate (Ritalin) 50-70mg IR
Diazepam (Valium) 20-30mg
Alprazolam (Xanax) 1mg
Pregabalin (Lyrica) 300mg
Ethanol-Gin 2.oz every 40min or so

For a tolerant user, 240lbs / 6’ male this cocktail is very effective…..it’s not weak by any means, but not in the danger zone in any way….for ME

Adding a dopaminergic stimulant to an opioid is absolutely essential ….it enhances the analgesic painkilling properties of the opioid, it reduced sedation and improves cognitive function and enhanced vigilance…..also, both have VERY robust mood-boosting properties and can be extremely euphoric & pleasurable

Valium is the best benzodiazepine of earth, Anxiolytic & muscle relaxation
Xanax is the most euphoric benzodiazepine with antidepressant properties due to the significant dopamine increase as compared to all other benzodiazepine compounds

Pregabalin (Lyrica) 300-450mg is simply amazing to add to a cocktail…..Very robust anxiolytic & mood-boosting properties, in addition to being an anticonvulsant gabapentinoid

Oxycodone is the most euphoric potent opioid painkiller ever synthesized (besides Diamorphine & Dilaudid) but I’m on Methadone 100mg daily ….which is also reasonably pleasurable, and a VERY potent & effective long acting opioid analgesic

….the oral Brompton Cocktail 🍸 (all tablets pulverized and powder in glass dissolved in hot water, add juice to mask the bitter taste and drink. 30-45min onset creeps in / 1h near full effects and you’re NICE 😊

a Speedball (Oxycodone & Ritalin) (Heroin & Cocaine) ….Ive slammed both …..VERY pleasurable & euphoric. A euphoric opioid and a dopaminergic stimulant. Hands down ultimate drug combo
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I have all the ingredients to give this a try and so, I absolutely will be doing so in the near future, thanks for the tip.

I am also on methadone and after some trial and error came up with this little combo which I found very nice.

Methadone is already on board, just taken as usual daily dose.

Start with thc oil, I was doing a mild dose of about 15mg.
Give the oil about an hour to approach peak affect, then add diazepam, again moderate dose seemed to suit the combo the best, 10-20mg according to tolerance.

Wait about 45 min for diazepam to kick in nicely.

Final step, oral morphine sulphate, I would prepare 2 x 100mg sr morphine tabs by crushing thoroughly and adding to about 30ml of water then downing it like a shot of whiskey.

I would then just go lay down and listen to music and the physical euphoria would be quite amazing, it was really really enjoyable.

So to try your combo, I would swap the thc oil for a stim, I have easy access to dex amphetamine tabs, do you think they would do the trick.

Add 1mg of alprazolam to the diazepam along with some pregabalin.

Then add the alcohol as the last step, do you think the particular type of alcohol would really matter?

Again thanks for this it sounds right up my alley.
 
Babygirl25 said:
I'd have to say that back in the day I was scripted at my drug clinic for 4 ( but he always gave me 6) 10 ml amps of diamorphine, 6 10 ml amps of diazepam , and 10 mg tabs in case it wasn't convenient to hit up where I was. 6 I don't recall the dose of black bombers although I believe they were 20 mgs and they were actually called Durophet. They were capsules that at the lowest dose were white the the next dose up we're the half the capsule was white and the other half was black. Then you had the pure black capsules. Then to get me off to sleep I got 4 mandrax a night. When they stopped prescribing these I got 6doriden a night. I'd sell half of my monthly script and still have enough left to cater for my own needs. The thing is I needed the diamorphine but it made me sleepy so that's why I got the bombers. But they made me very edgy which was ok unless you'd been awake for 2 days and nights and that's where the valium amps came in. Then as the bombers were not making me wired due to the valium, they still worked well enough that you just couldn't sleep and 2 mandrax a night did the trick. Sometimes I'd be really stupid and add the occasional tuinal into the equation and wake up on a hospital ward with just mattresses lining each side of one of the old fashioned hospital wards, called barb wards. Each big London hospital had a barb wards back then. You'd take a tuinal capsule and you'd get the best high for about 15- 20 minutes and that was it. You'd pass out and an ambulance would drop you off at the nearest barb wZrd that had a mattress free. Unfortunately these barbiturates were really quite lethal if you had taken a large, more potent cut of china white and then used even the smallest dose of tuinal. And I'm certain that there were only 2 mgs of these capsules available. I truly believe that due to my being scripted for the drugs I've mentioned above and only ever taking the higher mgm of tuinal when I'd only had a couple of amps of diamorphine saved my life. Usually I stick with the smaller mgm of tuinal. They were called Christmas trees as one end was, IIRC one end was blue turquoise blue and the other end was a bright orangy red colour which made the blue colour stand out more. There were so many really enjoyable but lethal drugs combo's when mixed with street drugs. Again I got everything I needed from the drugs on my script, I knew the dosage and that it wasn't cut with God knows what. If I wanted a different high I'd either increase the dose of, usually the bombers and diamorphine or just take another amp of valium. The high from each drug individually was awesome and at night time a couple of mandies was like a very softtuinsl type high but you'd gradually get sleepy. It was a soft high as opposed to a ferocious almost brutal high like tuinal. Don't get me wrong as tuinal, whilst feeling brutal got you up there so quickly it was amazing. But the hime from that high and put cold was about 15- 20 mins, max. I hope I've described it as others who were around back then, remember them. It's quite a fond recollection although this was a time when I lost a lot of friends due to various barbs that were about back then.
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I wish I could get a doc to prescribe me something like this, sounds to good to be true.
Were you getting the six amps every day?
Is it still possible to be prescribed stuff like that anymore, what's your situation now if you don't mind me asking.
 
vision conquest said:
I wish I could get a doc to prescribe me something like this, sounds to good to be true.
Were you getting the six amps every day?
Is it still possible to be prescribed stuff like that anymore, what's your situation now if you don't mind me asking.
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Yeah, six amps a day.. the doctors were naive back then. Mind you my Dr was a realist as he knew if he didn't give me that script I'd buy street drugs that might be cut to fuck, although back then they were suite pure, just so many that could be lethal still on the market and easily available.

Today I'm prescribed pregabalin 300mgs every twelve hours. We 60 mgs of oxycontin s/r and 20 I/r oxynorm for breakthrough pain. I rarely take anything else. Well maybe the odd pipe, but not often.

Babygirl. X
 
I found pregabl8n crapy unless i took whole bl8ster strips in one dose but made me a bit too wobbly so got my doctor to cancel them
 
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