Benzos Tolerance to Benzodiazepines

[Drugs_Are_For_Losers]

What bout drinking one beer with a tolerance

 

[Quasimoto]

What bout drinking one beer with a tolerance

One beer on top of benzos isn't going to kill you, but do not make a habit of it. That combo is a world of fuck. It's all too easy for one beer to turn into 8, and then you wake up in handcuffs. And yes, one night of drinking on top of benzos raises your tolerance significantly. It really fries your GABA receptors.

I'm not trying to give you a hard time, but are you looking for therapeutic anxiety relief, or are you trying to get high? No judgement here, I'm just trying to spare you from the hell I've experienced.

 

[Drugs_Are_For_Losers]

Onenight of drinking on top of benzos raises your tolerance significantly. It really fries your GABA receptors

I meant one beer a day not one night of drinking, and I know you're not trying to give me a hard time everyone is pretty chill on this site.

 

[marcoman]

Seriously with these comments?

 

[specialrelativity]

Xanax is alprazolam and vice versa. Ativan is lorazepam. Etizolam is? I became highly physically dependent. How about you? It doesn't really bother me, though since I quit. It tooke about five days. Tapering down. Cheers.

 

[marcoman]

I've taken oxy, k pins and a few beers together daily for years. Zero issues. What's all the scare comments? That's why I asked..is this for real?

 

[marcoman]

Benzos start to lose their effectiveness after about a month of daily use.

Do NOT take 6mg per day! With zero tolerance you shouldn't take more than .5mg per day at first. 6mg is a ridiculous dose and will leave you with horrible rebound and dependence after just a couple weeks.

Where you getting this from? Just your own personal experience? Plus you just say "benzos" and list one specific mg. They're different in equivalency. OP is talking about Xanax. Not all benzos are the same but you appear to putting them all in one category. Sorry, but am I misunderstanding you or not comprehending you correctly? And again..you say they lose their effectiveness in a month? Where you getting this from?

 

[Quasimoto]

Where you getting this from? Just your own personal experience?

Sorry, but am I misunderstanding you or not comprehending you correctly? And again..you say they lose their effectiveness in a month? Where you getting this from?

From medical literature, and my own extensive experience. They begin to lose their ^therapeutic effectiveness after about a month. The therapeutic index, when the drawbacks of the medication begin to outweigh the benefits. After about a month, the anxiety relief wanes as hard tolerance sets in and you need the benzo to just feel normal. It does not cure anxiety, it makes it worse in the end.

Plus you just say "benzos" and list one specific mg.

OP is talking about Xanax.

Within the context of the thread I was clearly talking about xanax. I'm very familiar with it, I was prescribed 2mg per day when I was just 17.

Not all benzos are the same but you appear to putting them all in one category.

Ehhhh, I'm not going to say they are all the same, but in the broader generalization of drug effects they kinda are all the same, yeah. Their effects, tolerance, dependence, and general prognosis of treatment are generally the same. The biggest difference is their respective half lives.

 

[Tyronavirus]

Where you getting this from? Just your own personal experience?

I've taken oxy, k pins and a few beers together daily for years. Zero issues. What's all the scare comments? That's why I asked..is this for real?

 

[Drugs_Are_For_Losers]

I like to have an ice cold beer with my pizza

 

[paracetaminophen]

Tolerance develops pretty rapidly to the sedative (hypnotic) and motor effects. But tolerance to the anxiolytic effects develops quite slowly if at all.
From the study:

If developing at all, tolerance to the anxiolytic effects seems to develop more slowly compared to tolerance to the hypnotic effects. [...] Another double-blind study allocated 180 chronically anxious outpatients to diazepam (15 to 40 mg/day) and found that prolonged diazepam treatment (6–22 weeks) did not result in tolerance to the anxiolytic effects of diazepam [68]. Furthermore, additional studies all show a continuing anxiolytic effect, at least for panic disorder [69–72], generalized anxiety disorder [73], and social phobia [74–76].

and

In conclusion, there is no solid evidence from the existing literature that anxiolytic efficacy declines following chronic benzodiazepine use in humans.

Don't get me wrong, long term benzo use has a bunch of side effects (I should know), but the idea that they are going to just quit working for anxiety one day isn't really that solid.
As long as you use them responsibly and keep to the lowest effective dose, you should be fine. Bartards give them a bad name.
They should still be a last resort though, in my opinion. Much like antipsychotics (but that's for another time...)

 

[Drugs_Are_For_Losers]

T09 many words too gry

 

[JackARoe]

Looks like someone mixed some alcohol in with benzos

 

[Quasimoto]

Looks like someone mixed some alcohol in with benzos

OP took 6mg of xanax with no tolerance and then got into the beer

 

[vlzinspace]

i also wanted to add i didn't seem to have any nerve damage whilst on them, it was the withdrawal that gave my foot neuropathy, to which the numbness remains.

using sparingly bottom line

 

[Drugs_Are_For_Losers]

So rhe anxiolytic effects wont work after two weeks?

 

[Drugs_Are_For_Losers]

Tolerance develops pretty rapidly to the sedative (hypnotic) and motor effects. But tolerance to the anxiolytic effects develops quite slowly if at all.
From the study:

and

Don't get me wrong, long term benzo use has a bunch of side effects (I should know), but the idea that they are going to just quit working for anxiety one day isn't really that solid.
As long as you use them responsibly and keep to the lowest effective dose, you should be fine. Bartards give them a bad name.
They should still be a last resort though, in my opinion. Much like antipsychotics (but that's for another time...)

Where did you find that study?

Stupid me all I had to do was click on that thing.

Does that apply to all benzodiazepines or only alprazolam and diazepam?

 

[jasperkent]

It does not cure anxiety, it makes it worse in the end.

This is why long-term benzo use is so problematic. The individual on benzos feels like they need to increase their dosage when they really need to taper & quit.

 

[paracetaminophen]

Where did you find that study?

Stupid me all I had to do was click on that thing.

Does that apply to all benzodiazepines or only alprazolam and diazepam?

It should apply to all benzodiazepines.

 

[emkee_reinvented]

Hi bluelighters and bluelets

Quick question: with no tolerance at all to Alprazolam could a person take it without it losing it's anxiolytic effect?

I spose it would depend on age, weight, sex etc wouldn't it or no?

Used to have a liberal dr. so asking was no problem to get a prescription.

So i was prescribed 30/ 0.25 mg pills per 2 months. Sometimes they made,
a mistake with the dose and i got 30/ 0.5 mg instead. If so i stretched em out.
Never got addicted, neither tolerant. Reason i don t get the 6 mg dose.

1 mg daily, or even 0.25, would be the path to physical dependence and tolerance.
Take as needed don t equal daily. And imo raising your dose, don t keep it low.

Tried to kill a DOC [long acting psychedelic] trip with a heroic dose,
and that didn t work either.

But i seem not prone to anxiety, used them pure for insomnia.
And for Alcohol DETOX, and confirm they don t work when taken daily.
In DETOX 5 day s Diazepam. Though that works 3 weeks.