red22
Bluelighter
- Joined
- Nov 23, 2009
- Messages
- 2,061
𝚀𝚞𝚘𝚝𝚎𝚜:
I'm just not in agreement with synthetics. I've experimented with a lot of these different things over a period of years, and I sat down one day and said, you know I'm just buggering myself up with this shit, and it's not taking me anywhere that I can't get with psilocybin, DMT, LSD, and mescaline. These are naturally occurring.[ ✱ ] They work. Your body has a "history" of experience with them. People have used them for thousands and thousands of generations, and we've adapted to them because they exist in nature, they're there for us to use, they're the planetary hormones that allow us to bring our consciousness forward to the next level. They've always been used this way.[/i]
Owsley Stanley. Interview with an Alchemist: Bear Owsley Interview. Bruce Eisner's Writings. 2004-01-10.
✱I believe that they will find a plant which contains the exact diethylamide of lysergic acid in natural form. In alkaline alcoholic medium the isomers of the amines of lysergic acid will reach an equilibrium. This equilibrium will be a certain percentage of the iso compound, and a certain percentage of the normal compound. Of all the compounds listed experimentally by [Hofmann], LSD has the highest ratio of active to inactive isomers in the equilibrated mixture, it runs 88-12. Of all the compounds, and it lists about 20 of them, it has the highest ratio of active to inactive. This means that nature favours the active form of LSD over the inactive by a considerable margin.
I’ve tried probably 20 tryptamine analogs.
None of them beat good quality shrooms. Seriously.
You have to get good shrooms tho.
MET was nice tho…. Didn’t like the DMT analogs. They were great actually, but came with a hangover.
The hangover is what I didn’t like about analogs.
Shrooms give you the exact opposite of a hangover.
ZydePunk77, 2024-09-17, re: The best base tryptamines in your experience and why?
I've never had a better experience with microdosing than eating a peyote button (Lophophora fricii or diffusa, I can't recall right now) that was about 2/3 the size of my fist. It wasn't going to survive some rot that I cut out of it, so I just ate it like an apple and it was unironically one of the best stimulants/antidepressants I've ever come upon in my entire life.
How did it compare to synthetic phens?
It felt exceptionally separate from anything else, I suspect that the tetrahydroisoquinolines inside of Lophophora sp. plants really set them apart. San Pedro is unique in some ways, but every time I've ever eaten a Loph they feel like a totally unique class of drugs. Much more intense with a simultaneous stimulation and sedation, unique visual effects, far more euphoria and mood boosting, very empathogenic, less sexually active but more of a drive to like, cuddle and bond if that makes sense.
@Esperighanto, 2025-09-03, post-16311956 & post-16311959
Have you ever tried synthetic mescaline? How does that experience compare to working with the master plant?
I tried synthetic mescaline once, maybe 10 years ago, because I was curious. The first thing I noticed is that the experience is totally different. With the synthetic, you have visions, but there's no guidance. It's like you're floating around without a teacher to direct you. You're having an experience, but you're not learning anything or being shown where you need to grow.
With Wachumita [San Pedro], there's an intelligence guiding you. The plant spirit sits with you, shows you specific things you need to see, asks you questions, and helps you understand your life. It's a relationship. The plant has thousands of years of wisdom and knows exactly what you need. With the synthetic, it's just chemistry. You get some effects, but the spirit is not there. There's no master, no teacher.
The other big difference is that Wachumita has many alkaloids and compounds that work together, not just mescaline. It's a whole, balanced plant intelligence. The synthetic is just one isolated molecule. Some people think they can just take the active ingredient and get the same effect, but they're missing the point. It's like trying to learn from a book instead of sitting with a real teacher who knows you personally.
Psychonaut POV
[5-min read] Q&A with Jhaimy Alvarez-Acosta, Andean Wisdom Keeper. Henry Winslow. 2025-11-09. Tricycle Day.
It is sooooo so much more than just chemical compounds. I’ve had the pharmahuasca over here and mutiople different kinds that westerners try to recreate.
There is an active spirit only found with the combination of plants taught to the INDIGENOUS elders passed down from lineage to lineage.
Again, it’s so, so much more than just chemical compounds
shamanstaab, 2026-03-04, https://www.instagram.com/onjaemalyszka/p/DVESa6skccE/
When making a tea from the whole plant, you are extracting the essence of the plant intelligence from its very flesh, not just isolating the alkaloids. In the alchemic method ‘Spagyrics’ developed by Paracelsus, often considered the father of modern medicine, the ashes of the plant are commonly burnt and then blended back into an alcohol-extracted tincture. Friends who have experimented with this procedure report that a Spagyric tincture of ayahuasca is much more potent than a normal tea prepared from the ayahuasca vine. Ayahuasca leaf can technically be used to make ayahuasca brews, but does not tend to carry the brew, or really ‘take’ the ayahuasca drinker on a solid journey, just as thicker and older vine tends to carry the brew much further than younger and thinner vine. Many people will not know the difference, but I find that the older, thicker vine will allow me to travel to certain places and bring through certain sounds and frequencies that are just not possible with younger and thinner vine.
It came to my attention after an embarrassing number of years, that taking freebase crystal DMT orally was not as potent, colourful, or clear as taking the equivalent amount of DMT in a tea that was brewed from the plant. For many years, I couldn’t see how there could be a difference, but after doing some comparisons, it was obvious that the tea was much better, and the experiences resulting from the crystalline extract were inferior. You could take twice or even three times as much DMT crystal as the equivalent in brew, and the experience from the crystal would never be as bright or full as that from the tea! Why could this be? Well, when extracting, chemicals like sodium hydroxide and liquid petrochemical hydrocarbon solvents are commonly used. In this chemical extraction process, it seems that some dimensions and qualities of the tryptamine molecules are compromised. Also, there is the factor of isolating the alkaloids from the rest of the plant. For example, there are very few people who say that extracted pure mescaline from the cactus is as potent or full bodied compared to when they take the dried powder or tea made from the cactus flesh.
Different batches of Syrian rue work differently – some are stronger and fuller, some are brighter. Some of these brews made from Syrian rue will be like a fine, full-bodied, and sophisticated wine – while other brews will be like some cheap red wine! I have tasted fresh Syrian rue from seeds in Jordan, and after taking two seeds from the pod sublingually, I noticed mild psychoactive effects. I have also had Syrian rue that may have been languishing in stockpiles for a decade or more at the Persian grocery store that left me feeling listless and depressed.
Julian Palmer. Articulations: On the Utilisation and Meanings of Psychedelics. 2014. Chapter 4. Ayahuasca / Dosages of Tryptamines and Beta-Carbolines
An acid high often seems to be a by-product of magnifying the mind, whereas with mushrooms and cactus one feels they are in touch with something ancient, spiritual, and personal.
… The negative aspects of LSD's signature that many users report are a " metallic edge " (a slight grating on the nerves), and sometimes an overbearing intensity that some psychedelics, such as mushrooms, tend not to produce.
… The mescaline experience is my favorite of the traditional psychedelics (LSD, psilocybin, mescaline). I find it has the advantages of acid: a lucid, penetrating, focused ability of the mind, rather than the more dreamy, drifting state I get from mushrooms. However, I feel totally relaxed with mescaline, even calmer than I feel on mushrooms, and there's no trace of the metallic edge usually felt on acid. …
The Essential Psychedelic Guide. D. M. Turner. 1994. I - Traditional Psychedelics / LSD - Molecule of Perfection & I - Traditional Psychedelics / Mescaline: Peyote &
San Pedro Cactus
I'm just not in agreement with synthetics. I've experimented with a lot of these different things over a period of years, and I sat down one day and said, you know I'm just buggering myself up with this shit, and it's not taking me anywhere that I can't get with psilocybin, DMT, LSD, and mescaline. These are naturally occurring.[ ✱ ] They work. Your body has a "history" of experience with them. People have used them for thousands and thousands of generations, and we've adapted to them because they exist in nature, they're there for us to use, they're the planetary hormones that allow us to bring our consciousness forward to the next level. They've always been used this way.[/i]
Owsley Stanley. Interview with an Alchemist: Bear Owsley Interview. Bruce Eisner's Writings. 2004-01-10.
✱I believe that they will find a plant which contains the exact diethylamide of lysergic acid in natural form. In alkaline alcoholic medium the isomers of the amines of lysergic acid will reach an equilibrium. This equilibrium will be a certain percentage of the iso compound, and a certain percentage of the normal compound. Of all the compounds listed experimentally by [Hofmann], LSD has the highest ratio of active to inactive isomers in the equilibrated mixture, it runs 88-12. Of all the compounds, and it lists about 20 of them, it has the highest ratio of active to inactive. This means that nature favours the active form of LSD over the inactive by a considerable margin.
I’ve tried probably 20 tryptamine analogs.
None of them beat good quality shrooms. Seriously.
You have to get good shrooms tho.
MET was nice tho…. Didn’t like the DMT analogs. They were great actually, but came with a hangover.
The hangover is what I didn’t like about analogs.
Shrooms give you the exact opposite of a hangover.
ZydePunk77, 2024-09-17, re: The best base tryptamines in your experience and why?
I've never had a better experience with microdosing than eating a peyote button (Lophophora fricii or diffusa, I can't recall right now) that was about 2/3 the size of my fist. It wasn't going to survive some rot that I cut out of it, so I just ate it like an apple and it was unironically one of the best stimulants/antidepressants I've ever come upon in my entire life.
How did it compare to synthetic phens?
It felt exceptionally separate from anything else, I suspect that the tetrahydroisoquinolines inside of Lophophora sp. plants really set them apart. San Pedro is unique in some ways, but every time I've ever eaten a Loph they feel like a totally unique class of drugs. Much more intense with a simultaneous stimulation and sedation, unique visual effects, far more euphoria and mood boosting, very empathogenic, less sexually active but more of a drive to like, cuddle and bond if that makes sense.
@Esperighanto, 2025-09-03, post-16311956 & post-16311959
Have you ever tried synthetic mescaline? How does that experience compare to working with the master plant?
I tried synthetic mescaline once, maybe 10 years ago, because I was curious. The first thing I noticed is that the experience is totally different. With the synthetic, you have visions, but there's no guidance. It's like you're floating around without a teacher to direct you. You're having an experience, but you're not learning anything or being shown where you need to grow.
With Wachumita [San Pedro], there's an intelligence guiding you. The plant spirit sits with you, shows you specific things you need to see, asks you questions, and helps you understand your life. It's a relationship. The plant has thousands of years of wisdom and knows exactly what you need. With the synthetic, it's just chemistry. You get some effects, but the spirit is not there. There's no master, no teacher.
The other big difference is that Wachumita has many alkaloids and compounds that work together, not just mescaline. It's a whole, balanced plant intelligence. The synthetic is just one isolated molecule. Some people think they can just take the active ingredient and get the same effect, but they're missing the point. It's like trying to learn from a book instead of sitting with a real teacher who knows you personally.
Psychonaut POV
[5-min read] Q&A with Jhaimy Alvarez-Acosta, Andean Wisdom Keeper. Henry Winslow. 2025-11-09. Tricycle Day.
It is sooooo so much more than just chemical compounds. I’ve had the pharmahuasca over here and mutiople different kinds that westerners try to recreate.
There is an active spirit only found with the combination of plants taught to the INDIGENOUS elders passed down from lineage to lineage.
Again, it’s so, so much more than just chemical compounds
shamanstaab, 2026-03-04, https://www.instagram.com/onjaemalyszka/p/DVESa6skccE/
When making a tea from the whole plant, you are extracting the essence of the plant intelligence from its very flesh, not just isolating the alkaloids. In the alchemic method ‘Spagyrics’ developed by Paracelsus, often considered the father of modern medicine, the ashes of the plant are commonly burnt and then blended back into an alcohol-extracted tincture. Friends who have experimented with this procedure report that a Spagyric tincture of ayahuasca is much more potent than a normal tea prepared from the ayahuasca vine. Ayahuasca leaf can technically be used to make ayahuasca brews, but does not tend to carry the brew, or really ‘take’ the ayahuasca drinker on a solid journey, just as thicker and older vine tends to carry the brew much further than younger and thinner vine. Many people will not know the difference, but I find that the older, thicker vine will allow me to travel to certain places and bring through certain sounds and frequencies that are just not possible with younger and thinner vine.
It came to my attention after an embarrassing number of years, that taking freebase crystal DMT orally was not as potent, colourful, or clear as taking the equivalent amount of DMT in a tea that was brewed from the plant. For many years, I couldn’t see how there could be a difference, but after doing some comparisons, it was obvious that the tea was much better, and the experiences resulting from the crystalline extract were inferior. You could take twice or even three times as much DMT crystal as the equivalent in brew, and the experience from the crystal would never be as bright or full as that from the tea! Why could this be? Well, when extracting, chemicals like sodium hydroxide and liquid petrochemical hydrocarbon solvents are commonly used. In this chemical extraction process, it seems that some dimensions and qualities of the tryptamine molecules are compromised. Also, there is the factor of isolating the alkaloids from the rest of the plant. For example, there are very few people who say that extracted pure mescaline from the cactus is as potent or full bodied compared to when they take the dried powder or tea made from the cactus flesh.
Different batches of Syrian rue work differently – some are stronger and fuller, some are brighter. Some of these brews made from Syrian rue will be like a fine, full-bodied, and sophisticated wine – while other brews will be like some cheap red wine! I have tasted fresh Syrian rue from seeds in Jordan, and after taking two seeds from the pod sublingually, I noticed mild psychoactive effects. I have also had Syrian rue that may have been languishing in stockpiles for a decade or more at the Persian grocery store that left me feeling listless and depressed.
Julian Palmer. Articulations: On the Utilisation and Meanings of Psychedelics. 2014. Chapter 4. Ayahuasca / Dosages of Tryptamines and Beta-Carbolines
An acid high often seems to be a by-product of magnifying the mind, whereas with mushrooms and cactus one feels they are in touch with something ancient, spiritual, and personal.
… The negative aspects of LSD's signature that many users report are a " metallic edge " (a slight grating on the nerves), and sometimes an overbearing intensity that some psychedelics, such as mushrooms, tend not to produce.
… The mescaline experience is my favorite of the traditional psychedelics (LSD, psilocybin, mescaline). I find it has the advantages of acid: a lucid, penetrating, focused ability of the mind, rather than the more dreamy, drifting state I get from mushrooms. However, I feel totally relaxed with mescaline, even calmer than I feel on mushrooms, and there's no trace of the metallic edge usually felt on acid. …
The Essential Psychedelic Guide. D. M. Turner. 1994. I - Traditional Psychedelics / LSD - Molecule of Perfection & I - Traditional Psychedelics / Mescaline: Peyote &
San Pedro Cactus
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