Do you know which tissue it was converted in?
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NMI Moderators: Coffeeshroom
I am a druggie and nobody knows!
- Thread starter ashman918
- Start date
Didgital
Bluelight Crew
Converted? I'm not sure I understand. I imagine they were injecting IV though. Just very difficult to imagine doing it with pure THC which unless heated or dissolved in a carrier oil, is almost a solid.
The thc-o-phosphate was a semisynthetic derivative.
Point is you technically can shoot up weed.
Just wondering which tissue contains the phosphatase that chops it up into THC. The prodrug would need to be transported to the tissue with the enzyme then its rate limited by enzyme kinetics
But this topic may be more suited for NS&PD lol
Didgital
Bluelight Crew
No lets totally overwhelm the new BLer with dense scientific terminology!! :D
"Enzymatic Hydrolysis of THC Phosphate. As-
THC phosphate could be hydrolyzed enzymatically, but
the affinity to the enzyme did not appear to be high (see
Table I). As-THC (12%) was liberated from the phos-
phate by hydrolysis with alkaline phosphatase a t the
optimum pH of 9.6 for 60 min. As summarized in Table
I, when incubated with the mouse liver homogenate for 60
min, 24.5 and 29.2% of the phosphate was hydrolyzed a t
pH 9.6 and 5.0, respectively."
Like most cannabinoids, the liver.ashman918
Greenlighter
Lol, umm no. Is the even possibleThe man is a pioneer. Welcome to Blue Light sir
TheGyattDamnRizzler
Bluelighter
- Joined
- Dec 13, 2024
- Messages
- 392
What up texas ranger. Being sober is the big cringe am I rite guys?
LucidSDreamr
Bluelighter
as long as you micron filter your nuggets and heat them up in a spoon first
Ok, to be serious; do you think that maybe you have become so accustomed to using drugs that life seems bland, boring and pointless without them. Could it be that the drugs are talking and that little devil on your shoulder got the angel on your other shoulder high and now because of long term drug use you can't see life without. Let's explore this, shall we?( I do care and me being bored is a coincidence).
1. Are you dissatisfied with your wife. Aka she is twice the woman you bargained for at the alter?
Is your love life non existent?
Is the communication in your marriage and issue?
Do you really love your wife or has there been trouble or has she become distant or have the two of you grown apart?
Your relationship with your wife a major factor in your unhappiness with life? If so is it possible to fix this if it as problem?
Is the excitement gone in your relationship and can it be repaired?
2. Your job. Are you happy with your job or is it just to pay the bills.
Is it a dead end job or possibly a job that pays to well to leave?
Do you feel trapped by your job?
3.your kids. If you are white are any of children gingers?
Do your kids love and or respect you.
Do feel like your kids are a source of aggravation? Is it because they are disobedient and or disrespectful?
Do you have a good, bad, or a distant relationship and are they a source of grief?
4. Do you live in a boring area?
Do you have any close and good healthy friendships?
Do you feel distant from others even if you were never into drugs?
5. Did you once have hobbies or strong interests before your drug use?
Is there anytime that you were happy without drugs?
6. Personal trauma: do you have any unresolved issues in your life that were traumatic and drugs are a way of coping?
Any personal issues that you are trying to suppress and is your drug use a way to self medicate or hide from your inner unresolved issues?
7. Could this be a mid life crises and instead of a sports car you have drugs?
Do you have issues with the life you choose and now regret it?
We are all of course getting older but do you feel time is slipping away?
8.Is your family life in general not feel fulfilling?
Do you regret marriage and kids?
Did you sacrifice any realistic dreams by becoming and living as a regular family man?
9. With any of these issues do you feel like you could talk to your wife and would she be supportive of you in trying to find happiness outside of drugs?
10. Are you, or have you reached a point where even the drugs won't help you? Are you having any trouble or loss of control in your life?
Do you truly hate life without drugs; or is that the drugs speaking?
11. Is there any chance of happy life drug free?
Was there a time when you were happy and married with kids and drug drug free
12. What future do you see using drugs and having a normal life?
What have been the costs physically, mentally, emotionally, financially, and to your future?
These are some questions you might want to ask yourself and I am judging, I can't hmm. The reason I would ask is simple: why are you very defensive? Your tone denotes uncertainty in the secret life of drug use you are a part of. Are there deeper reasons? Do you just like getting high? Is there something more behind your use or not? Are you at some sort of crossroads and you came here?
Hey, we are just having fun. Things are unfortunately different now than before. But hopefully you can use this place. Think about the questions I asked( no the one about shooting weed) but the others because of the uncertainty or is the effects of something that are causing this uncertainty that you seem to have. What has made you question your use or need reassurance?Lol, umm no. Is the even possible
Didgital
Bluelight Crew
Yeah if your phosphorylate the lone OH group on THC it becomes a water soluble prodrug. Yes it is possible, with a chemical modification
Hey and welcome
I personally think there a lot of functioning addicts out there but as for the part of thinking no one knows, im not sure.
But unless you have unlimited funds, sustaining it is where a problem will be and followed by more. that and then there is the havoc it's doing to your body.
I know the fact of being sober sounds and feels shitty to most but then maybe adrenaline sports or hobbies could become a good replacement in the future that is. Depending on how you really wanna deal with it.
emkee_reinvented
Bluelighter
In equivalent ratio s there probably more functional addicts, then non-functional,
functioning as functional, non-addict s [assuming 5 o'clock daily drinking = not a addiction].
Ellie Wright
Greenlighter
I share a similar sentiment, like I don't wanna get too cocky and say I never act high, though I work around people who smoke weed and drink alcohol so they know I am likely an alcoholic, but beyond that everyone probably assumes I am just retarded and not also constantly on DXM, but when I take too much my family gets suspicious so I say I just smoked a bowl and go hide.
Back then when I was doing amph daily and going to work, it eventually made me so numb-minded, as often happens with daily use of stims, that when I quit and went to work sober first time since picking up that bad habit, I was immediately accused of being high because I was so much more lively.
Obviously things that happened also during my use contributed to situation and me coming to work sober was just the last straw that broke the camels back.
Bad decisions, bad consequences. Deep regret and shame.
What have you been doing since this?
Kellsee
Bluelighter
- Joined
- Jul 2, 2021
- Messages
- 3,380
Im just gonna take this and write it on a post it note and place it somewhere so I’ll see it everyday lol
Rainman1964
Bluelighter
The majority of the time, I believe this is true; however, as it seems to be with everything in life, genetics have a play at this. I literally knew two people who were lifetime users of meth. Both women and one lived to 84, and the other, 81. These women were both in good spirits and one ate anything she wanted, and the other, believe it or not was a health food freak. She never drank alcohol, ate sugar or gluten, and was a physical therapist and marathon racer up to her 60s. I am 60 now, but I watched her from the time I was 19, use dope. She actually started with cocaine, but when "crank" hit the scene, I never saw her stop. Her mother and grandmother on her father's side both lived to almost 100. She also had beautiful skin. She died when she tripped at home and hit her head and died shortly thereafter, home alone, because she didn't want anyone around her. She was sharp mentally also!!
The other gal had been using since the mid-80s. She started smoking it on foil, then the glass pipe and would go back and forth between smoking and snorting it. She smoked weed like a chimney and had a vodka grapefruit in her hand every time I saw her. I don't think I ever saw her sit down to a regular meal, eat a salad or anything green for that matter, and I think she lived off of yogurt and Doritos. She's the one who lived to be 84. She had a great sense of humor and ran a day care into her 70s. She still did some babysitting up to the time she died. I never saw her with so much as a cold. Oh, and she smoked Marlboro Red in between the pot and meth. I think she snorted chopped up pills sometimes. I do not know much about her family or health history, but she died in her sleep.
There are more people who will not have a good outcome, but there are a few folks out there where the meth did not seem to lower the quality of living for them, and lived a relatively healthy and long life. Who knows?
Best,
V