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RCs Which is the worst GABAergic sedative you have ever taken? (Benzos, Z-Drugs, ludes, Phenibut, GBL etc.)

We both have the exact opposite opinion, because I would say that alprazolam is one of the worst benzos.
It suppresses your anxiety so much that you're absolutely emotionless, and this causes dysphoria in many cases.

Better options are:
  • Temazepam
  • Tetrazepam
  • Clonazepam
  • Flunitrazepam
Those are not as good as the four above, but also solid:
  • Oxazepam
  • Diazepam
  • Chlordiazepoxid
  • Rilmazafone
And those are as bad as alprazolam:
  • Lorazepam (that's a tiny bit better than Alprazolam)
  • Bretazenil (that's on the same level as alprazolam)
Especially the hypnotically acting benzos are the ones that cause the most euphoria.

But yeah, overall Mephenaqualone/Methaqualone (Quaaludes) are the best sedatives and GABAergics, and after that comes Phenibut in my opinion.
It's interesting to see how different opinions can be on things, especially when seeing that it's truly the complete opposite.

Stay safe and wish you a great Christmas Eve, Mana0909

@Mana0909 :

>>>I snipped this out of one of your posts as it perked my interest:

Temazepam: After Clonazepam, the strongest benzodiazepine for seizures and also considered the benzo with one of the strongest euphoria. Like Clonazepam, it's extremely sedating and lets you feel very light. Because of the mild-moderate euphoria, it doesn't make you an emotionless robot, and on top of that, it's also the benzodiazepine that causes the strongest muscle relaxation. This means that it can help against chronic pain and increase the effect of painkillers such as ASS, Pamol, Naproxen, as well as opioids like Tramadol. The addiction potential is especially high here, same as Clonazepam, because of its high affinity for seizure reduction and muscle relaxation, meaning a withdrawal could cause heavy muscle spasms and deadly cramps.
--------------------------------------------------------------------
>>>Thanks for your posts and sharing your knowledge. I have been on clonazepam/klonopin aka k-pins for many years,...same dose for years at .5mg 3x a day for 6+years or so and on and off over my lifetime (but more on than off) I'm a benzo guy, they just seem to normalize me and rock my world without being all fkd up. I also take oxycodone for pain management (multiple injuries from lifetime of ice hockey from peewee, college to minors) My dose of oxy is 25mg, 3x day (minimal to say the least) But recently my doc cut me off from my k-pins as she said the mix of oxy and them were putting me at a high risk of ODing. I donlt know what crawled up her butt but all of sudden she stopped my k-pin script.

I've tried a lot of the benzos over my lifetime, I'm 66 yrs old. I find K-pins (sorry thats what I grew up calling them) but they seem to be the best for me as they last long and I do'tt need much to keep me mellow, clear-headed and normalized. A close second would be Valium. But Xanax, Ambien, I fricken hate. Xanax hits me too hard and is gone in no time and I almost get a crappy crash feeing of it. Ambien puts me in an unpleasant fog and I can't function. Anyway, as I said , My sketchy docturd' took me of my k pins in June/July and I'm currently searching out for a new doc who may script me a benzo (hopefully my k-pins) But, your mention of Temazepam I have never heard of. And it sounds right up my alley and may be a better version of my beloved k-pins.

So questions: Temazepam. Is this something docs script for? .. as I've never had any docs bring it up to me. And there was a time when they were trying all kinds of stuff on me with finally figuring out clonaz'/k-pins was best for me. But never a mention of this Temazepam. I know it's still a benzo and docs may refuse to script it to me because of the BS "OD issue." is it something I could ask a doc to script for me? And are there any other avenues to get it from? It def' sounds like something I;d like to try for sure. An why isn't it more popular? Thoughts? Either DM in my box or post here to share for others. Thanks !
 
Temazepam. Is this something docs script for?
Depends on the country you're in, usually it's only found in certain areas of Western Europe and Asia iirc? It's extremely uncommon in the US or Canada though.

I know it's still a benzo and docs may refuse to script it to me because of the BS "OD issue." is it something I could ask a doc to script for me? And are there any other avenues to get it from?
What is this OD issue you're talking about? Genuinely curious, it's almost impossible to OD on benzos which is why this piqued my curiosity. Asking a doc for a benzo scrip is a quick way to get flagged as "drug seeking", and asking Bluelight for avenues to acquire drugs is a violation of terms of use, I'd suggest probably editing that out of your comment tbh. If you're not comfortable using darknet marketplaces, deal with your lack of benzos as getting them off the street is a huge pain in the ass and is quite dangerous to do safely. Maybe kava or other similar drugs could help, or you could try to get a scrip for something like pregabalin or gabapentin as a sort of "comfort drug" in place of clonazepam.
 
Going slightly off topic, but does anyone else have any experience combining muscimol with other GABAergics? Unlike others, muscimol is a direct GABA agonist which is structurally almost identical to GABA itself, and has higher affinity than GABA itself. This leads to higher levels of extracellular free GABA, which in turn influences other desirable neurotransmitters.

It potentiates other GABAergics nicely, particularly positive allosteric modulators like benzos.

By itself, in higher doses, the effects resemble that of z-drugs which can possibly be undesirable and cause hallucinations and delusions. I much preferred to combine lower or medium doses with other GABAergics. In lower doses by itself, the effect is somewhat mild but decent. Mild sedative and hypnotic properties, not much of any anxiolytic or muscle relaxant properties. Even more cool, it does not cause any rebound or withdrawal, and one paper suggested it can actually reverse benzo dependence by stimulating the receptor just enough to reverse the receptor's rigidity (cause of benzo dependence). I tried it for this purpose, and it did seem to work but I can't confirm that. At the very least, it helps a lot during the taper process by potentiating the benzo without ruining the taper process.

If you want to experiment with it, I would highly suggest finding isolated or synthetic muscimol, though. Don't buy it from a vape shop, those amanita extracts are often very dirty and/or are not properly prepared and contain ibotenic acid (neurotoxic) and muscarine (has unpleasant effects and potentially dangerous). Some of those products don't even contain amanita at all and are laced with synthetic tryptamines, so you have to be really careful with buying it. It's also legal to boot!

I wish somebody would start producing gaboxadol.
 
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I wish somebody would start producing gaboxadol.
I do my best not to dive too deep into chemistry on BL, there are other forums for that, but the synthesis of gaboxadol is a profoundly, unspeakably, incomprehensibly intense pain in the ass for a drug that would barely sell in the first place relative to easier to synthesize, more well known substances that would sell better. Markets follow the dynamics of capitalism, so I doubt we'll ever see somebody seriously producing large amounts of synthetic gaboxadol, or muscimol, or thiomuscimol from what I've read up on so far.
 
I do my best not to dive too deep into chemistry on BL, there are other forums for that, but the synthesis of gaboxadol is a profoundly, unspeakably, incomprehensibly intense pain in the ass for a drug that would barely sell in the first place relative to easier to synthesize, more well known substances that would sell better. Markets follow the dynamics of capitalism, so I doubt we'll ever see somebody seriously producing large amounts of synthetic gaboxadol, or muscimol, or thiomuscimol from what I've read up on so far.
That's interesting. I assumed it wouldn't be too difficult because it seems like a structurally simple and small molecule. But I am no chemist and wouldn't know.

I didn't know muscimol was difficult to synthesize. I have seen it for sale for reasonable prices, but did not confirm if it was legit or not. Maybe it was highly pure isolated muscimol from the mushroom (it was pure white powder). Or maybe it was a scam, but I recall reports saying it wasn't and was good product, but I may be wrong.
 
That's interesting. I assumed it wouldn't be too difficult because it seems like a structurally simple and small molecule. But I am no chemist and wouldn't know.

I didn't know muscimol was difficult to synthesize. I have seen it for sale for reasonable prices, but did not confirm if it was legit or not. Maybe it was highly pure isolated muscimol from the mushroom (it was pure white powder). Or maybe it was a scam, but I recall reports saying it wasn't and was good product, but I may be wrong.
I bet that most people would find even lab-grade, 99% pure muscimol to be a mid-grade or just generally shitty product, most people do not like these drugs whatsoever in my experience. When somebody could make a benzodiazepine that's guaranteed to sell and is active at 1mg, whereas muscimol requires 8-15mg (Peredy T, Bruce R (2014). "Mushrooms, Ibotenic Acid". Encyclopedia of Toxicology. pp. 412–413), and muscimol is pretty universally disliked whereas those potent benzos like clonazepam or bromazolam are pretty well enjoyed, chemists living in capitalist societies have very little motivation to pursue things like optimizing muscimol syntheses.

If people worked at it hard enough, they could probably find easier ways towards these compounds. Gaboxadol is the only one that seems worthwhile though, and man it's by far the hardest of the aforementioned compounds to synthesize and all known syntheses involve super esoteric precursors and some dangerous steps that involve high pressure hydrogenation.
 
I enjoyed muscimol for what it is; a mild sedative and hypnotic, but more importantly a legal and easily accessible one (in the US). I tried high dose once, and it was interesting, but not enjoyable enough for me to try it again.

Combining it to modulate other drugs is really where it shines.

I didn't get the impression it was universally disliked, but I know the mushrooms are. The vape shop I used to buy a decent extract from sells relatively high volumes and often sells out.
 
Depends on the country you're in, usually it's only found in certain areas of Western Europe and Asia iirc? It's extremely uncommon in the US or Canada though.


What is this OD issue you're talking about? Genuinely curious, it's almost impossible to OD on benzos which is why this piqued my curiosity. Asking a doc for a benzo scrip is a quick way to get flagged as "drug seeking", and asking Bluelight for avenues to acquire drugs is a violation of terms of use, I'd suggest probably editing that out of your comment tbh. If you're not comfortab If nyou go back and re-read my post I explained wny le using darknet marketplaces, deal with your lack of benzos as getting them off the street is a huge pain in the ass and is quite dangerous to do safely. Maybe kava or other similar drugs could help, or you could try to get a scrip for something like pregabalin or gabapentin as a sort of "comfort drug" in place of clonazepam.
If you go back and re-read my post, I clearly stated why my doc stopped my script for benzos and the OD issue. I will repeat it again for you. I was taking oxycodone AND k-pins at the same time ( I also listed in that same post the actual doses I was taking which were very low) Yet my doc (out of the blue) suddenly decided it was an OD risk (benzos and opioids together). Even my pharmacist had told me that I was not at any real risk of ODing of what I was taking AND had been taking for many years. I'm still not sure what got my doc all skittish about it but that's her reasoning she stopped my k-pin script. She continued the oxys but said she was cutting off the k-pins.

As far as me going to another doctor and "asking for benzos" I'll explain in detail. For one, thing, I'm not a dummy. Over my years I have been through a gauntlet of trial and errors for the proper medications to help me with my mental issues and the benzos (k-pin and valium) were two that were most effective and that I tolerated well...and even with my oxys. With any new doc I explain this to them as they always want to have me "try this one" or "try that one" and I just sincerely and honestly just tell tell them that I've been through the ringer with trial and errors and this is what works best for me (those two I mentioned)

I'm 66, take good care of myself, dress well when I go out, clean-shaven, etc - and really don't look like your typical doctor shopping junkie. I'm not some grunged redneck marching into an office telling them to script me off some benzos asap, lol . Plus the fact that I've taken the same dosages for years without any increases must have an impact on doctors that clearly shows I'm not abusing them. I've also tried the holistic route to no avail.

It's my strong conviction that I have 2 medications that work for me. I have no real side effects. I don't want to try other drugs as I've been through that and I surely don't care to try brand new stuff and be a pharma guinae pig. Clonazapam, valium and oxycodone have been around for quite awhile and IMO are tried and true. And at my age I'd like to think I can have still have some say as to weighing the risks versus benefits of the 2 drugs that have worked for me. But as we all know, that's no longer the case anymore. But it never hurts to voice your opinion. It wasn't long ago that docs handed out drugs like candy and now the pendulum has swung so far the other way they don't give out any. And now we have people suffering, and a lot of them are the elderly. I think I'm pretty fortunate to be getting oxys and who knows if that'll be next to get cut off. Thus leaving no other options than hitting the streets or overseas. Where I live maybe a walk over the border to where tacos are popular may work too.

But my comment to mana909 was in regards to tamazepam, a drug I've never heard of before (and sounds like one I MAY be interested in trying if I cant obtain k-pins or valiums) and if he could shed more light on it. I'll do my own research on it as well. I did see as you stated it is not very prevalent (and maybe not even obtainable) in the the US though.

edit: I once was trialed with Gabapentin and felt like a zombie, horrid for my body chemistry, etc. So that too is off my list.
 
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@Mana0909 :

>>>I snipped this out of one of your posts as it perked my interest:

Temazepam: After Clonazepam, the strongest benzodiazepine for seizures and also considered the benzo with one of the strongest euphoria. Like Clonazepam, it's extremely sedating and lets you feel very light. Because of the mild-moderate euphoria, it doesn't make you an emotionless robot, and on top of that, it's also the benzodiazepine that causes the strongest muscle relaxation. This means that it can help against chronic pain and increase the effect of painkillers such as ASS, Pamol, Naproxen, as well as opioids like Tramadol. The addiction potential is especially high here, same as Clonazepam, because of its high affinity for seizure reduction and muscle relaxation, meaning a withdrawal could cause heavy muscle spasms and deadly cramps.
--------------------------------------------------------------------
>>>Thanks for your posts and sharing your knowledge. I have been on clonazepam/klonopin aka k-pins for many years,...same dose for years at .5mg 3x a day for 6+years or so and on and off over my lifetime (but more on than off) I'm a benzo guy, they just seem to normalize me and rock my world without being all fkd up. I also take oxycodone for pain management (multiple injuries from lifetime of ice hockey from peewee, college to minors) My dose of oxy is 25mg, 3x day (minimal to say the least) But recently my doc cut me off from my k-pins as she said the mix of oxy and them were putting me at a high risk of ODing. I donlt know what crawled up her butt but all of sudden she stopped my k-pin script.

I've tried a lot of the benzos over my lifetime, I'm 66 yrs old. I find K-pins (sorry thats what I grew up calling them) but they seem to be the best for me as they last long and I do'tt need much to keep me mellow, clear-headed and normalized. A close second would be Valium. But Xanax, Ambien, I fricken hate. Xanax hits me too hard and is gone in no time and I almost get a crappy crash feeing of it. Ambien puts me in an unpleasant fog and I can't function. Anyway, as I said , My sketchy docturd' took me of my k pins in June/July and I'm currently searching out for a new doc who may script me a benzo (hopefully my k-pins) But, your mention of Temazepam I have never heard of. And it sounds right up my alley and may be a better version of my beloved k-pins.

So questions: Temazepam. Is this something docs script for? .. as I've never had any docs bring it up to me. And there was a time when they were trying all kinds of stuff on me with finally figuring out clonaz'/k-pins was best for me. But never a mention of this Temazepam. I know it's still a benzo and docs may refuse to script it to me because of the BS "OD issue." is it something I could ask a doc to script for me? And are there any other avenues to get it from? It def' sounds like something I;d like to try for sure. An why isn't it more popular? Thoughts? Either DM in my box or post here to share for others. Thanks !
Good morning,

Temazepam is indeed a benzodiazepine, and it is primarily prescribed for short-term treatment of insomnia. It is known for its sedative and muscle-relaxant properties, which can be beneficial for those who need help with sleep and muscle relaxation. However, it is not typically prescribed for anxiety or long-term use due to its potential for dependence and tolerance.

Given your history with clonazepam (Klonopin) and your current use of oxycodone, your doctor's concerns about the risk of overdose are valid. Combining benzodiazepines with opioids can significantly increase the risk of respiratory depression, which can be life-threatening. This is likely why your doctor decided to discontinue your clonazepam prescription.

You are 66 years old, so the chance is high that they could prescribe it. The reason why Temazepam isn't that popular is its strong euphoria and risks. Like I've said, the withdrawal can be severe and could cause chronic pain as well as seizures. It's a benzodiazepine that you can only get legally if other options like Clonazepam didn't work. So there isn't a 1:1 guide, but I still wish you the best. In your situation, you should try it and be very convincing. Show them that you truly need it for living. In other words, go on the emotional line, not too much, but you know what I mean.

Here are a few suggestions that might help manage your symptoms:

  1. Non-Benzodiazepine Alternatives: There are other medications that can help with anxiety and muscle relaxation without the same risks as benzodiazepines. These include certain antidepressants, anticonvulsants, and muscle relaxants.
  2. Behavioral Therapies: Cognitive-behavioral therapy (CBT) and other forms of therapy can be effective in managing anxiety and improving sleep without the need for medication.
  3. Lifestyle Changes: Regular exercise, a healthy diet, and good sleep hygiene can all contribute to better overall health and may reduce the need for medication.
  4. Pain Management: If your primary concern is pain, working with a pain specialist to explore other pain management strategies might be beneficial. This could include physical therapy, acupuncture, or other non-pharmacological treatments.
Temazepam is sadly rarely prescribed in general, but considering everything you might get it

[SIZE=3]marcoman[/SIZE]

But my comment to mana909 was in regards to tamazepam, a drug I've never heard of before (and sounds like one I MAY be interested in trying if I cant obtain k-pins or valiums) and if he could shed more light on it. I'll do my own research on it as well. I did see as you stated it is not very prevalent (and maybe not even obtainable) in the the US though.
EDIT: Thanks but im not a guy-


Stay safe and take care! Mana0909
 
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PS: here is a total overview of Temazepam, everything that I know

Dosage and Administration​

Temazepam is typically taken orally in the form of a capsule. The usual recommended dose for adults is 7.5 to 30 mg taken at bedtime. The exact dosage may vary depending on the individual's age, medical condition, and response to treatment. It is important to follow the prescribing doctor's instructions and not to exceed the recommended dose. Its the strongest muscle relexation Benzo available and the second strongest one against seizures. It could and will increase the effect of Oxycodone, but that would be insanely life threatening.

Pharmacokinetics​

  • Absorption: Temazepam is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 30 to 90 minutes after ingestion.
  • Distribution: It is widely distributed throughout the body and crosses the blood-brain barrier to exert its effects on the central nervous system.
  • Metabolism: Temazepam is metabolized in the liver, primarily through conjugation with glucuronic acid.
  • Elimination: The drug and its metabolites are excreted mainly in the urine. The elimination half-life of Temazepam is approximately 8 to 15 hours, which means it stays in the body for a relatively short duration.

Side Effects​

Like all medications, Temazepam can cause side effects. Common side effects include:
  • Drowsiness
  • Dizziness
  • Fatigue
  • Headache
  • Nausea
More serious side effects, although rare, can include:
  • Confusion
  • Memory problems
  • Mood changes
  • Difficulty breathing
  • Allergic reactions

Precautions and Warnings​

  • Dependence and Withdrawal: Long-term use of Temazepam can lead to physical and psychological dependence. Abrupt discontinuation can result in withdrawal symptoms such as anxiety, agitation, and insomnia. It is important to taper off the medication gradually under medical supervision.
  • Interactions: Temazepam can interact with other medications, including other central nervous system depressants, alcohol, and certain antidepressants. These interactions can increase the risk of side effects and should be discussed with a healthcare provider.
  • Pregnancy and Breastfeeding: Temazepam is not recommended for use during pregnancy or breastfeeding due to potential risks to the fetus or infant.

Conclusion​

Temazepam is a valuable medication for the short-term treatment of insomnia and anxiety, thanks to its sedative, muscle-relaxant, and anxiolytic properties. However, it is important to use it under the guidance of a healthcare provider or someone that you can trust and that has much experience in this field to minimize the risk of dependence and other potential side effects.

For more detailed information, you can refer to sources like Wikipedia and Gelbe Liste (German Side).

I hope this helps! If you have any further questions, feel free to ask.

Stay Safe, Mana0909
 
Tetrazepam and Clobazepam, could also be very promising for your symptoms, because Temazepam is a also very strong hypnotic (I’m sorry I forgot to mention that in my listing).

If you want, we can chat via DM's since this sounds like a very private and sensitive topic. I have deactivated them, but because I really think it's important that you get the right treatment, I could open them for you. Just write here if you would prefer to chat in private rather than in this thread I've created.

I always close my DM's by default, because I get simps on every social media platform, and my darling fiancée hates those losers. I hope that's understandable.

Stay safe and have a great day, Mana0909
 
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@marcoman I definitely would listen to the doc about the OD risk being serious between those two and especially so as you get older. Your convictions vs. Modern medicine is quite the David vs. Goliath pitch here.

If you take the border crossing route, you won't find oxycodone btw, nowadays just tramadol and HIGHLY irregularly pressed benzos. Drugsdata's farmapram entries are a great example, if you want to poke around how insanely unevenly Mexican drugs are made, especially the sketchy ones sold to random people who approach looking for "ketamine for their horse" or whatever. If you do try to acquire specifically Temazepam, order it from countries where it's known to be prescribed, and always, always reagent test. If you can, send a sample from each batch you acquire (and homogenize to the best of your abilities) to a testing laboratory, hitting unexpected hyperpotent opioids in pressed benzos is something I've done here and there and it fucking sucked. If I didn't have an active high dose oxycodone tolerance at the time, I'd have likely died.

It also might be a good idea to keep backups on hand just in case your scrip gets cancelled. For benzos there's not much of an adequate replacement, but for oxycodone, enough 7-OH-Mitragynine (a naturally occurring alkaloid in kratom, which you can now buy in relatively pure forms) could certainly suffice.
 
@marcoman maybe thats also interesting for you.

Im very sorry to hear that,

I would strongly advice then to change meds, here is a very long list with four stages (this took me 140 minutes, I would be happy over a like or a heart, thanks)

First Stage of Medications (1 out of 4) Those are the most effective and most difficult ones to obtain.

Flunitrazepam (Rohypnol): Known as the "date-rape drug" due to its strong hypnotic effects. It's one of the hardest benzodiazepines to get a prescription for, along with Temazepam and Tetrazepam. Recommended only for short-term use due to its strong euphoria.

  • Dosage: 1-2 mg, 30 minutes before bedtime.
  • Onset: 15-20 minutes.
  • Duration: 3-7 hours, residual effects up to 12 hours.
  • Rebound: Moderate, but can last between 2 - 24 hours.
Disadvantages:
  • Higher addiction potential than other benzodiazepines like Alprazolam (Xanax) or Diazepam (Valium).
  • Rebound effect can last longer than the drug's main effects.
  • Overdose can be dangerous due to strong hypnotic effects.
  • Extremely difficult to get a prescription.
Advantages:
  • More effective than Z-Drugs, Gabapentinoids, and most other benzodiazepines.
  • Fast onset and well-researched.
  • Low toxicity relative to dose but potentially lethal when mixed with depressants.

Temazepam (Restoril): A benzodiazepine used for short-term treatment of insomnia. It has strong sedative, muscle-relaxant, and anxiolytic properties, making it effective against muscle spasms and chronic pain.
  • Dosage: 7.5 to 30 mg at bedtime.
  • Onset: 5-10 minutes.
  • Duration: 5-13 hours.
  • Rebound: Moderate, but can last between 0-7 hours.
Disadvantages:
  • Almost impossible to get a prescription, even harder than Flunitrazepam.
  • Higher addiction potential, with severe withdrawal symptoms.
  • Overdose can be fatal due to strong sedation and hypnotic effects.
Advantages:
  • More effective than Z-Drugs, Gabapentinoids, and most other benzodiazepines.
  • Extremely rapid onset and well-researched.
  • Long main effect duration with shorter and rarer rebound effects compared to Flunitrazepam.

Quinazolinone - Methaqualone/Mephenaqualone (Quaaludes): A Quinazolinone analogue, even though "Mephenaqualone" is a modern analogue of "Methaqualone." The effects caused by these sedatives are the same, with Mephenaqualone being more potent. Methaqualone, also known as "Lemon714 and Quaaludes," was sold worldwide in 1951. It had strong hypnotic, sedative, muscle relaxant, and anxiolytic effects combined with high euphoria. It was banned in 1984 due to its high addiction, dependence, and abuse potential.

Methaqualone (Lemon714/Quaaludes):
  • Dosage: 300-450 mg, 25 minutes before bedtime.
  • Onset: 30 minutes.
  • Duration: 2-4 hours.
  • Rebound: Strong, which can last between 3-6 hours.
Mephenaqualone (RC-Quaaludes/Anzu):
  • Dosage: 300-450 mg, 25 minutes before bedtime.
  • Onset: 30 minutes.
  • Duration: 2-4 hours.
  • Rebound: Strong, which can last between 3-6 hours.
Disadvantages:

  • Getting Methaqualone is almost impossible, even in the Darknet marketplace. Mephenaqualone is also difficult to obtain and soon will be out of production.
  • Highest addiction and dependence potential with severe withdrawal symptoms.
  • Combining with alcohol can be fatal.
  • Short main duration despite claims of longer effects.
Advantages:

  • Highly effective for strong insomnia.
  • Does not disrupt REM sleep as much as benzodiazepines and Z-drugs.
  • Smooth and pleasant effects, comparable to opioids.

Second Stage of Medications (2 out of 4) Those are still very effective, but not on the same level as the first stage.

Flurazepam (Dalmane): A long-acting benzodiazepine used for treating insomnia. It has strong sedative and muscle-relaxant properties. It might be a long acting benzodiazepine, but the main effect duration lasts in average round about 3 - 4 hours.

  • Dosage: 15-30 mg at bedtime.
  • Onset: 5-15 minutes.
  • Duration: 2 - 6 hours.
  • Rebound: Moderate, but can last up to 24 hours.
Disadvantages:
  • Moderate addiction potential.
  • Long duration can cause next-day drowsiness.
  • Overdose risk, especially when combined with other CNS depressants.
Advantages:
  • Effective for maintaining sleep throughout the night.
  • Well-researched and widely used.
  • Easier to obtain than Rohypnol and Restoril.

Estazolam (ProSom): A benzodiazepine with strong sedative and hypnotic properties, used for treating severe insomnia.

  • Dosage: 1-2 mg at bedtime.
  • Onset: 30-60 minutes.
  • Duration: 6-12 hours.
  • Rebound: Moderate, which can last up to 24 hours.

Disadvantages:
  • Moderate addiction potential.
  • Can cause next-day drowsiness.
  • Overdose risk, especially when combined with other CNS depressants.
Advantages:
  • Effective for maintaining sleep throughout the night.
  • Well-researched and widely used.
  • Easier to obtain than Rohypnol and Restoril.

Nitrazepam (Mogadon): A benzodiazepine with strong sedative and muscle-relaxant properties, used for treating severe insomnia.

  • Dosage: 5-10 mg at bedtime.
  • Onset: 30-60 minutes.
  • Duration: 6-12 hours.
  • Rebound: Mild - Moderate, but can last up to 24 hours.

Disadvantages:
  • Moderate addiction potential.
  • Can cause next-day drowsiness.
  • Overdose risk, especially when combined with other CNS depressants.
Advantages:
  • Effective for maintaining sleep throughout the night.
  • Well-researched and widely used.
  • Easier to obtain than Rohypnol and Restoril.

Third Stage of Medications (3 out of 4) Those are the regulars that your doctors will give you.

Oxazepam (Serax): A low-potency benzodiazepine with sedative and anxiolytic properties, often used for anxiety and insomnia.
  • Dosage: 10-30 mg at bedtime.
  • Onset: 30-60 minutes.
  • Duration: 6-12 hours.
  • Rebound: Mild - Moderate, but can last up to 24 hours.
Disadvantages:
  • Moderate addiction potential.
  • Can cause next-day drowsiness.
  • Overdose risk, especially when combined with other CNS depressants.
Advantages:
  • Effective for both sleep induction and anxiety reduction.
  • Well-researched and widely used.
  • Easier to obtain than stronger benzodiazepines.

Zolpidem (Ambien): A Z-drug with strong hypnotic effects, used for short-term treatment of insomnia.
  • Dosage: 10-20 mg at bedtime
  • Onset: 15-30 minutes
  • Duration: 4-9 hours.
  • Rebound: Mild, lasts up to 2-4 hours.
Disadvantages:
  • Moderate addiction potential.
  • Can cause next-day drowsiness and unusual behaviors.
  • Overdose risk, especially when combined with other CNS depressants.
Advantages:
  • Effective for sleep induction.
  • Rapid onset and well-researched.
  • Easier to obtain than stronger hypnotics.

Gabapentin (Neurontin): A gabapentinoid used for neuropathic pain and off-label for insomnia.
  • Dosage: 300-900mg at bedtime.
  • Onset: 1-2 hours.
  • Duration: 5-7 hours.
  • Rebound: Minimal.
Disadvantages:
  1. Moderate addiction potential.
  2. Can cause next-day drowsiness and dizziness.
  3. Overdose risk, especially when combined with other CNS depressants.
Advantages:
  1. Effective for both pain management and sleep induction.
  2. Well-researched and widely used.
  3. Easier to obtain than stronger sedatives.

Last Stage of Medications (4 out of 4)
those are the easiest to get and most of them are even legal

Diphenhydramine (Benadryl): An antihistamine with sedative properties, commonly used for short-term treatment of insomnia. It can cause moderate depressive thoughts and dysphoria and is also known for causing anxiety and paranoia, but it has a surprisingly strong hypnotic and sedation effects and its cheap.

  • Dosage: 25-50 mg at bedtime.
  • Onset: 30-60 minutes.
  • Duration: 4-6 hours.
  • Rebound: Minimal.
Disadvantages:
  1. Can cause next-day drowsiness.
  2. Tolerance can develop with prolonged use.
  3. Potential for anticholinergic side effects.
Advantages:
  1. Easily available over-the-counter.
  2. Effective for short-term use.
  3. Non-prescription option for mild insomnia.

Trazodone: An antidepressant with sedative properties, often prescribed off-label for insomnia. The base substance has a duration of 3-6 Hours, while the long-acting aka. "Extended-release Trazodone" has shown durations up to 10 hours.

  • Dosage: 25-100 mg at bedtime.
  • Onset: 30-60 minutes.
  • Duration: 3-10 hours.
  • Rebound: Minima - Mild.
Disadvantages:
  1. Can cause next-day drowsiness and dizziness.
  2. Potential for priapism (rare).
  3. Requires a prescription.
Advantages:
  1. Effective for both sleep induction and maintenance.
  2. Non-addictive.
  3. Widely prescribed and well-researched.

Doxylamine (Unisom): An antihistamine with sedative properties, commonly used for short-term treatment of insomnia. It is very well known to cause mild dysphoria, anxiety and paranoia, but those side effects are weaker then those of: Diphenhydramine (Benadryl)

  • Dosage: 25 mg at bedtime.
  • Onset: 20-60 minutes.
  • Duration: 2-5 hours.
  • Rebound: Minimal.
Disadvantages:
  1. Can cause next-day drowsiness.
  2. Tolerance can develop with prolonged use.
  3. Potential for anticholinergic side effects.
Advantages:
  1. Easily available over-the-counter.
  2. Effective for short-term use.
  3. Non-prescription option for mild insomnia.


Oooooof...this took me over 2 hours, 140 minutes to be exact.
I hope that this could help you and anyone who will read this. I would appreciate a like or a heart, because this was really a lot of work.

THIS IS A COPY, I'VE MADE THIS LIST ORIGINALLY FOR ANOTHER PERSON

Stay Safe, Manan0909
 
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Clonazepam is a great benzo for me because, like you've said, it's very sedating, relaxing, and lifts my mood significantly. It doesn't make me emotionless (which, in my opinion, is a bad effect because euphoria is an emotion, and I love to feel).

It also often gives me a feeling of need, like wanting to cuddle with my fiancé. Maybe you can relate to that.

Stay Safe, Mana0909
I get that feeling from diazepam personally. Mogadon is my fav, then Valium. Clonazepam and lorazepam make me black out from super low doses. But I can take 10-20 mg nitrazepam or 20-30mg diazepam with great results .
 
Yes, I feel you.

I also must say that low-potency benzos (except Rohypnol and Rivotril/Clonazepam) are way more enjoyable than those high-potency benzos. I honestly don't want to judge, but I have the feeling that people who are taking 5-10 Xan's or 15mg Lorazepam are very broken and poor individuals who just want to forget and erase their problems.

When I'm taking high doses of benzos, the euphoria and bliss turn into depressive and emotionless states. That's why I fully agree with you—low-mid dosages and low-potency benzodiazepines always bring the best results. I personally love to pop 1mg of Rohypnol/Flunitrazepam, which is a mild dose, and start to cuddle with my darling husband. It just feels so satisfying, you know? It's not a strong euphoria like on stimulants, opioids, etc. It's just subtle and relaxing.

I don't know if you have also experienced people who are popping 30 pills and behaving completely irrationally. Almost everyone who takes insane amounts of benzodiazepines is very vulnerable and emotionally broken. Maybe you also know or have seen that.

Stay safe, Mana0909
 
Small Info, To everyone who texted and visited this thread:

Thank you so much! It's incredibly motivating to share information and experiences about certain drugs. I've learned so many new things, and many have thanked me for helping them out. Everyone has been insanely relatable, deep, nice, mature, and respectable in my opinion. That's why I wish everyone a beautiful journey, a wonderful Christmas Eve, and a happy New Year, as well as much power and strength for the rest of your lives.

Never let yourself down, and when you truly need help, don't shy away from asking. In my opinion, it's better to do this in real life. Personally, I wouldn't share my current problems, but this forum is so mature and intelligent that you don't have to worry about such things.

Have a great day and stay safe, Mana0909
 
@Mana0909 0909 and @Esperighanto

Thank you both for sharing your expertise, I really appreciate it. @Mana0909 , sorry about my ignorance and assuming you were a guy.. maybe I'll call you womana0909? jk...lol
OK, back to this part of your post:
------------------
Temazepam (Restoril): A benzodiazepine used for short-term treatment of insomnia. It has strong sedative, muscle-relaxant, and anxiolytic properties, making it effective against muscle spasms and chronic pain.
  • Dosage: 7.5 to 30 mg at bedtime.
  • Onset: 5-10 minutes.
  • Duration: 5-13 hours.
  • Rebound: Moderate, but can last between 0-7 hours.
---------------------------------


I am wondering (after speaking to my doc) and reading what you posted about Temaz' if I could discontinue the oxycodone and try JUST the Temazepam... (if my doc would script it) As it may be the "Kill 2 birds with one stone" effect. If it would combat my chronic pain and reduce my restlessness/relax and help me sleep that would be nice. And she (my doc) wouldn't have to worry about anymore oxy/benzo combo regarding the overdose issue. I did think at one time (when she brought up she'd be cutting me off the benzo) about asking her to try going off the oxy and trying just taking the k-pins and see how that worked. But I didn't. She always have been open to discussions and doesn't take offense when I ask "well what about this drug" or "what other options do I have?" That part of her I like. And she did start me on the oxy and k-pins long a o when it was me who asked about taking them.

It does suck in a way that I have to choose between the two as the k-pin/oxy combination was the Holy Grail for me. The oxycodone lessened my pain levels and the k-pins helped to to relax- which without a doubt increased my overall quality of life. Even other people noticed the change in me, I wasn't all gimpy and crippled up and I wasn't as grumpy either. The benefits of a good nights sleep were huge too. Just having a sense of laughter is a huge plus because as a persons ages, laughter appears to not be as prevalent. Life is hard, for most of us, old age sneaks up and beats us up a bit. Add in chronic pain and life can get miserable real fast. That's why I try not to judge those people who appear grumpy and bitchy and "snap" easily. As I may not know what they are dealing with, physically, mentally or both. And yes, on the other side of the coin, I do admit it was a pleasant buzz as well (the oxy and k-pin combo) - but my main reason for taking them is more for the true medicinal part of it. And no, I don't tell my doc "oh yeah, it was a good buzz." lol
 
@marcoman I too deal with chronic pain despite being ~1/3 your age. I'm chronically ill (Crohn's/colitis, tons of surgical complications, etc) and I manage it with kratom, 7-OH, and cannabinoids. I'm not saying it necessarily will work, but maybe you could manage the pain with things like that and just get the benzo scrip from the doc? I'm not sure if that would be better, just throwing an idea out there.
 
@marcoman
Thank you for your reply,

I understand what you're trying to ask. You want to know if Temazepam (Restoril) could help with your chronic pain and seizures/muscle spasms, and this is very individual. You have to know that benzodiazepines aren't directly painkillers; they act as "pain modulators," meaning they increase the effects of analgesics in your blood.

EDIT: there is also a drug called "Clobazepam" its actually the same as Clonazepam, but less potent. A normal dose goes from 15 - 60 mg, but it has the same effect profile.
Im going to send in a picture where you can see the effect spectrum of some Benzos

This means that you could try it with a weaker opioid, such as MS Contin, which is a long-acting version of Morphine. If I were you, I would try to ask if you could maybe get another opioid.
 
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Wirkprofile_Benzodiazepine.gif



red = anxiolytic
yellow = sedative
blue = muscle relaxant
green = anticonvulsant

the two most important things are anticonvulsant and muscle relaxant, because those are the two effects that help against chronic pain and muscle spams (Tetrazepam isnt an option sadly, because this benzo is very toxic)
 
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