Site Feedback Update ‘Lysergamides’ prefix to the new term

red22

red22

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red22 said:
There are three main ergot alkaloid classes, clavines, ergoamides (lysergamides), and ergopeptides, with 3 belonging to the ergoamide class.

Biosynthesis and synthetic biology of psychoactive natural products. CS Jamieson, J Misa, Y Tang, JM Billingsley. Chem. Soc. Rev., 2021,50, 6950-7008. DOI: 10.1039/D1CS00065A (2.5 Lysergic acid and LSD)

Note that the three that is mentioned refers to the three natural ergoamides.


I think lysergamide has a sloppy feel. Sounds like something you’d hear on Nickelodean. Makes me think of someone slurping a beverage.
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Not sure what the question is here, you're asking us to change the Lysergamides prefix in Psychedelic Drugs to a different term?
 
There are folks here that have many levels of awareness of the subject. Some are just acquainted with street names and some are very proficient in chemistry and neurology. There is room on Bluelight to accommodate all these levels depending on which sub forum the posts may present themselves. The proposed term might be more appropriate in Neuroscience and Pharmacology Discussion than in say Drug Experiences, Trip Reports and Psychedelic Drugs, depending on the particular user's level of knowledge.

I think that alternative TAGs like the one @red22 proposed should be available, but I stop short of replacing it outright so that everyone can express themselves comfortably.
 
I have never in my life heard the term "ergoamide". However I can see without looking why it could be used. However, it is too general because it would include both Lysergic acid amides (lysergamides) and ergopeptides which are ergoline(s) linked to a tripeptide via an amide group. AFAIK, no one on bluelight or anywhere for that matter are trying to get high from consuming ergopeptides (aside from Krystal Chole, Leonard Pickard, and Gordon Todd Skinner; who all supposedly drank ergot wine)

So I don't really see a reason to distinguish between the two classes.

red22 said:
Note that the three that is mentioned refers to the three natural ergoamides
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None of the clavines even posess an amide functional group, so how are they even ergoamides?

en.wikipedia.org

Ergoline - Wikipedia

en.wikipedia.org en.wikipedia.org
en.wikipedia.org

Agroclavine - Wikipedia

en.wikipedia.org en.wikipedia.org
en.wikipedia.org

Elymoclavine - Wikipedia

en.wikipedia.org en.wikipedia.org
en.wikipedia.org

Festuclavine - Wikipedia

en.wikipedia.org en.wikipedia.org

And their role in psychoactivity is unknown or they're known to be toxic.
red22 said:
I think lysergamide has a sloppy feel
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Because you personally think that a word has a sloppy feel, even though it's been used by millions of people for decades and it's scientifically descriptive, that we should change the term to one that almost no one uses or has heard of?

All of the commonly discussed ergot compounds on bluelight (LSD, AL-LAD, MIPLA, LSA etc) are derivatives of Lysergic Acid. And they're amides, so lysergamide is a totally understandable term.

I don't know of a single post on BL about anyone consuming ergolines/clavines. I don't know of anyone besides myself that even posesses pure clavines. Nor do I know of anyone seriously discussing consumption of ergotamine (ergopeptides).

So my answer would be "Gtfo. No. Do not change or remove the Lysergamide tag. Why reinvent the wheel"

Lastly, while the paper you linked is very informative, even they don't mention the terms ergoamide or clavine, so I'm not sure why it's relevant to the point you're trying to make? After googling ergoamide, I can only find 2 papers that use that term.
 
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Thank you Danielle St. Germaine of ** No Drug Sources Please ** for using the new, better sounding word in your article:

"More recently, ergot alkaloids, in particular ergoamides, also known as lysergic acid amides, have gained notoriety through their use as synthetic precursors for lysergic acid diethylamide (LSD)."

Psychedelic Therapies Webinar Highlights. Danielle St. Germaine. 2023-12-14.

Although, this statement is probably inaccurate as lysergic acid amides are rarely used for LSD; the ergopeptine, ergotamine, is usually used, and I know Pickard was at least thinking about using ergocristine (another ergopeptine).
 
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Whatever they are named, they remain Lysergic s to me.
LysergAmides sounds pansy. ErgoAmides ... EgoAmides.
Chemical senseable, but as name a bit inaccurate, EgoLossAmides ?
 
emkee_reinvented said:
LysergAmides sounds pansy.
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Exactly. It's also redundant: lysergamide is a synonym for lysergic acid amide, while ergoamide is strictly a classification.

Didgital's post doesn't make sense.* Five upvotes… :LOL:


*For example, he says that the paper that I linked doesn't contain the word, ergoamide… where the hell does he think that italicized text came from? :LOL:
 
.... And here we go 👍


lasting positive psychological response.
 
Cheshire_Kat said:
There are folks here that have many levels of awareness of the subject. Some are just acquainted with street names and some are very proficient in chemistry and neurology. There is room on Bluelight to accommodate all these levels depending on which sub forum the posts may present themselves. The proposed term might be more appropriate in Neuroscience and Pharmacology Discussion than in say Drug Experiences, Trip Reports and Psychedelic Drugs, depending on the particular user's level of knowledge.

I think that alternative TAGs like the one @red22 proposed should be available, but I stop short of replacing it outright so that everyone can express themselves comfortably.
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add that to the fact that some use LLMs of their own for erowid's experience reports as just one of the examples. Later knowing that open source is open till you learn how to code yourself than you see that sometimes sytnax is just habituation as for semantics that is everything! as some things are not finished because everyone has their limitations and just forgot about it! So you carry on and stmble on something else entirely.

Accidents are building blocks of evolution and no we were less cognitive people or are programmed to think that way and taught that in schools, but not monkeys or apes. we don't wanna insult the beautiful animals.

Then they use or myself research of subjectivity and with outputs like 50 you have a result for what is your main one output! If I take lsd like 2 times more I will literal be to much metahuman to talk with my friends to anyone, Or am dellusional,

as for the where it should be yeah I also say on the place where people who goes deep to find the information like Neuroscience and pharmacology rather than on places where questions like is that magic or science what I saw on DMT to can I become pregnant if I shared my meth pipe (a stupid joke).

I always thought it is tryptamine or yeah it was known that ergot as fungi was thrown into vine or similar (what do you think marko Aurelije or Marcus Aurelius was taking?

love you people, stay safe and ask no matter how stupid is there is always someone stupid who will answer!

like me :-)
 
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