Cocaine Will Ritalin Enhance Cocaine High?

[hiii222]

If I'm doing a few lines of coke, would taking one or two Ritalin 10mg enhance the experience?
Primarily, will it prevent me from wanting to redose line after line?

I've done only 2 lines so far, been about an hour since the second one.
I was thinking maybe to plug one or two Ritalin (10 mg each) before I do a third line.

Any experience or knowledge on how this will interact with my coke high?

 

[ageingpartyfiend]

my own feeling is never to mix stimulants - it's usually uncomfortable at best

 

[bluecollartweeker]

Not in my experience, infact ritalin seems to cancel put any other stim i use it with, it either ruins the uephoria with sheer paranoia and overhwelming sensory perception or causes paradoxical sedation.

 

[emkee_reinvented]

Look up which ther affinty tfor the Dopmine receptor (and/ or effects on release of it).
As they are basiclky the same, Methylphenidate like a stripped down version of Cocaine.

But I never mixed them. Do know Cocaine cancels MDMA. And from here say also Amphetamine is effected.

Edit: good spelling and grammar emkee.

 

[Señor Moreno]

It will jeopardize and stain your cocaine high, but what it's for sure is that it will definitly enhance, worsen and prolonge your coke comedown

 

[Dextro .45]

Actually, both Cocaine & Ritalin have near identical MOA ….both are “Inverse Agonists” at the DAT/NET (Cocaine has SERT

Taking Cocaine or Ritalin FIRST…..,then Amphetamines an hour after will block Amphetamines action as it requires the Monoamine Transporters (which Ritalin & Cocaine block their function / reuptake inhibitor)

So you can take Adderall/Dexedrine/Vyvanse/Methamphetamine FIRST ….then after a few hours once all the monoamines have been released…..you can take Ritalin or Cocaine to prevent their reuptake…..further enhancing the actions of Stims

Although Amphetamines has multiple MOA …..mainly a monoamine releasing agent…..a triple reuptake inhibitor …..and further a MAOI ….a 3-shot combo

Cocaine & Ritalin are unique in that they aren’t typical reuptake inhibitors….they also induce the release of dopamine/noreph/serotonin ….unlike some weak ass shit like Bupropion NDRI

Ritalin (Methylphenidate) is a “Classic Amphetamine” on par with Cocaine, Benzedrine/Dexedrine/Methedrine, Phenmetrazine etc. CIBA Pharmaceuticals had marketed Ritalin 100mg glass vial multi use IV/IM injection …..10mg IV is like taking 80-100mg orally

 

[emkee_reinvented]

Lets just establish that Methylphenidate is inferiour to Cocaine.

Cocaine is shit but MPH is worse its the oral route that makes it somewhat better.
But a equivalent Cocaine pill imo would be the better alternative. But giving Cocaine to kids, not gonna happen.

So there came MPH or kiddie Coke.

 

[foodcrisis]

i think there are certain feelings people get from coke that if you are a certain type of person that likes specific feelings from coke then it's not really going to help stop you from doing line after line... but if you don't have a specific expectation of coke, then it will probably keep you stimulated and you might end up doing less... i just say this from my experience with the two drugs. i don't know if they do similar stuff to the brain or what, but there are some subtle or even pretty strong sensations from coke that i wouldn't get from even high dose ritalin.

 

[emkee_reinvented]

i think there are certain feelings people get from coke that if you are a certain type of person that likes specific feelings from coke then it's not really going to help stop you from doing line after line... but if you don't have a specific expectation of coke, then it will probably keep you stimulated and you might end up doing less... i just say this from my experience with the two drugs. i don't know if they do similar stuff to the brain or what, but there are some subtle or even pretty strong sensations from coke that i wouldn't get from even high dose ritalin.

They not the same thats certain, the high of Coke is better and more wellrounded.
But I never took it orally, its was just a speculation about how would equivalent oral dose compare to MPH?

You can snort MPH [well MPH, but the Talc in there as binder, aint so good for the lungs, i learned on Bluelight] so dont snort the crushed pills!

it's a bit like it with more side effects [might be they are just more noticeable by the lacking in effects compared to Coke], less fullfilling and maybe even more fiending. As there seems to be less reward. And it misses Serotonergic action which obviously balances Cocaines high. Does seem heavy on Nor-Epinephrine, but so does Coke. Less cardiotoxic, the main advantage + its chemically produced and doensthave a stigma like Yayo. Imagine a XR pill version of Coke.

That might just make it a nice ADHD drug.

 

[Rectify]

That's a good question. I would say probably, yes.

 

[Mr. Krinkle]

No - don't mix them - the ritalin will take over


because more is never enough right?

 

[Dextro .45]

Lets just establish that Methylphenidate is inferiour to Cocaine.

Cocaine is shit but MPH is worse its the oral route that makes it somewhat better.
But a equivalent Cocaine pill imo would be the better alternative. But giving Cocaine to kids, not gonna happen.

So there came MPH or kiddie Coke.

Mmmm…..if both were 100% pure pharmaceutical grade. Yes, cocaine is a triple reuptake inhibitor and very pleasurable low dose mood boosting antidepressant effects

Ritalin (Methylphenidate) is also a very highly respected and very effective and potent dopaminergic stimulant

 

[emkee_reinvented]

Mmmm…..if both were 100% pure pharmaceutical grade. Yes, cocaine is a triple reuptake inhibitor and very pleasurable low dose mood boosting antidepressant effects

Ritalin (Methylphenidate) is also a very highly respected and very effective and potent dopaminergic stimulant

Yeah think that balancing effect the extra Serotonin vs the irritating Nor-E & A. Un avoidable both with Coke and MPH,
could work out . Oral Cocaine never tried but after snorting MPH. Very alike.
What s the Oral availability of Coke pretty good right. MPH is very irredic both in absorption and clearance unlike Amphetamines.
One if the reason s making it a abundant med. imo

A Cocaine pill prefereable XR would be my preference over MPH, but Dextro-Amphetamine remains best so.

 

[MedicinalUser247]

Get drunk first, do the lines of Ritalin and then smoke Crack. That's how you get your bang for your buck. Although I don't advise doing this.

 

[neversickanymore]

Actually, both Cocaine & Ritalin have near identical MOA ….both are “Inverse Agonists” at the DAT/NET (Cocaine has SERT

Taking Cocaine or Ritalin FIRST…..,then Amphetamines an hour after will block Amphetamines action as it requires the Monoamine Transporters (which Ritalin & Cocaine block their function / reuptake inhibitor)

So you can take Adderall/Dexedrine/Vyvanse/Methamphetamine FIRST ….then after a few hours once all the monoamines have been released…..you can take Ritalin or Cocaine to prevent their reuptake…..further enhancing the actions of Stims

Although Amphetamines has multiple MOA …..mainly a monoamine releasing agent…..a triple reuptake inhibitor …..and further a MAOI ….a 3-shot combo

Cocaine & Ritalin are unique in that they aren’t typical reuptake inhibitors….they also induce the release of dopamine/noreph/serotonin ….unlike some weak ass shit like Bupropion NDRI

Ritalin (Methylphenidate) is a “Classic Amphetamine” on par with Cocaine, Benzedrine/Dexedrine/Methedrine, Phenmetrazine etc. CIBA Pharmaceuticals had marketed Ritalin 100mg glass vial multi use IV/IM injection …..10mg IV is like taking 80-100mg orally

I don't necessarily agree with this. amphetamine/dextroamphetamine certainly overpowers cocaine. I feel this is why it's such a strong candidate imho for a replacement therapy for cocaine use disorder. Some of the exploritory studies conducted around this were very short and the participants were well established free base addicts. The results were not very encouraging.

I belive the results will be dramatically different if the studies were undertaken long term. The heart of psychological cocaine addiction comes from the "memory" and experience of the rush. The vast majority of the rest of the experience is wretched. It's that brief rush of extreme pleasure obtained from freebase or IV that really drives the fantasy root of the psychological addiction.

Amphetamine/dextroamphetamine prevents this rush. It also prevents much of the unwanted and severely problematic after effects. It also has the ability to arrest or deter the severe compulsion to repeatedly redose and reupp. I believe the studies exploring the use of amp damp should be performed using six months with confirmed oral administration of the amp/ damp.

Im not confident in my opinion about Ritalin, but my hypothesis is that co administering it with coke would not have beneficial effects unless the coke was just garbage.

 

[neversickanymore]

Get drunk first, do the lines of Ritalin and then smoke Crack. That's how you get your bang for your buck. Although I don't advise doing this.

Thats the

https://www.sciencedirect.com/topics/neuroscience/cocaethylene#:~:text=Cocaethylene%20is%20a%20compound%20that,found%20in%20urine%20and%20blood.

if you get into this and get addicted every time you have a drink you will crave coke and even time you do coke you will crave a drink..

 

[Dextro .45]

I don't necessarily agree with this. amphetamine/dextroamphetamine certainly overpowers cocaine. I feel this is why it's such a strong candidate imho for a replacement therapy for cocaine use disorder. Some of the exploritory studies conducted around this were very short and the participants were well established free base addicts. The results were not very encouraging.

I belive the results will be dramatically different if the studies were undertaken long term. The heart of psychological cocaine addiction comes from the "memory" and experience of the rush. The vast majority of the rest of the experience is wretched. It's that brief rush of extreme pleasure obtained from freebase or IV that really drives the fantasy root of the psychological addiction.

Amphetamine/dextroamphetamine prevents this rush. It also prevents much of the unwanted and severely problematic after effects. It also has the ability to arrest or deter the severe compulsion to repeatedly redose and reupp. I believe the studies exploring the use of amp damp should be performed using six months with confirmed oral administration of the amp/ damp.

Im not confident in my opinion about Ritalin, but my hypothesis is that co administering it with coke would not have beneficial effects unless the coke was just garbage.

Well....in Agonist Replacement Therapy....in the case of illicit Cocaine....they would prescribe a dopaminergic stimulant, and a long acting amphetamine most likely

Vyvanse/Dexedrine Spansule XR/Adderall XR because it will provide the user with a potent dopaminergic stimulant at a low therapeutic dose, slower onset and longer duration....so the user can get clean from illicit cocaine

Heroin, there's oral Methadone and yes, even injectable Diamorphine

Ritalin is also used as Agonist Therapy for Cocaine addiction

Vyvanse usually for Meth addiction

The possibilities and options are vast