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Mental Health Coming off Invega/Xeplion (paliperidone) injections v 8.0

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went many months without taking supplements, 3 days ago I started supplementing again and eliminated caffeine, well what can I say, I feel much better, it will probably last a short time, but in the meantime I feel the benefits, fewer negative thoughts in the morning, prompt response, more positivity and energy, this year's goal to stop smoking cigarettes
 
Clopixol shut down my thoughts, I almost have no thoughts anymore. I also got nothing to say all the time it drives me nuts.
It also took my memories and the feeling of these memories away from me!
No thoughts, no memories... I hope I get that back.
 
SkavrsXeplion said:
went many months without taking supplements, 3 days ago I started supplementing again and eliminated caffeine, well what can I say, I feel much better, it will probably last a short time, but in the meantime I feel the benefits, fewer negative thoughts in the morning, prompt response, more positivity and energy, this year's goal to stop smoking cigarettes
Click to expand...
What are you taking for supplements?
 
Apparently high levels of IL-17 are found in people with schizophrenia and even with schizophrenia in remission.

www.ncbi.nlm.nih.gov

Type 17 Immune Response Facilitates Progression of Inflammation and Correlates with Cognition in Stable Schizophrenia

Dysregulation of the type 17 immune pathway has already been considered in schizophrenia and we previously measured decreased sera values of interleukin (IL)-17 in early stages. We further explored the possible correlation of IL-17 systemic levels with ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Higher levels of IL-17 in males is correlated with higher severity of anhedonia.

Higher levels of IL-17 (p=0.032), Th1- (p=0.002), Th2-(p=0.001) and non-T-(p=0.009) cell markers were associated with greater severity of anhedonia controlling for BMI, age, and gender. Gender also had a significant main effect on anhedonia, however, there was a significant gender by immune marker interaction only for IL-17 (p=0.050). Anhedonia severity increased with higher IL-17 in males (r=0.42, p=0.003) but not in females

www.ncbi.nlm.nih.gov

Association of T and non-T cell Cytokines with Anhedonia: Role of Gender Differences

Among individual depressive symptoms, anhedonia has been reliably associated with activation of the innate immune response. However, it is unclear whether this association extends to T cell cytokines and if gender differentially affects this association.Concentrations ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Risperidone and by extension paliperidone and invega reduce levels of IL-17a after 3 months of treatment.

A 3-month treatment with risperidone (1–6 mg/day) showed significant decreases in serum levels of IL-8, macrophage inflammatory protein (MIP)-1β, fractalkine, TNF-α, IL-7, IL 13, IL-17a, IL-23, and IL-21

www.frontiersin.org

Frontiers | Immunoendocrine Peripheral Effects Induced by Atypical Antipsychotics

<p>Atypical antipsychotics (AAP) or second-generation antipsychotics are the clinical option for schizophrenia treatment during acute psychoses, but they are...
www.frontiersin.org www.frontiersin.org

I propose that the severe anhedonia experienced by some people after stopping palaperidone invega, is because of rebound of IL-17 inflammatory cytokines.

Implementation of an IL-17 blocker like Secukinumab (SEC), Ixekizumab (IXE), and brodalumab (BROD) which are used to treat psoriasis, may provide relief.
 
anyone lost confidence? I have severe social anxiety know. I was HELLA confident before. How can I rehabilitate? It is rehabilitating.
 
BattlingInvega said:
anyone lost confidence? I have severe social anxiety know. I was HELLA confident before. How can I rehabilitate? It is rehabilitating.
Click to expand...
Hey there i see you joined in april? Lol I looked thrpugh your account, You said at seven months you were pretty shitty? 7.5 months is where I am at.
I am curious what changes you have seen from 7 months to where you are now, specifically in anhedonia.
To answer ur question when i first got injected it gave me severe social anxiety it was weird like I couldn’t talk to people.
But I work a customer service job around ppl all day and I have 0 anxiety my confidence is back.
 
Is it weird that invega sustenna has been the hardest thing ive gone through in my life? Lol is it just me? I mean I am young so I have not had as much life anyways..
 
It’s the hardest thing I’ve ever gone through too, I’ve also developed the worst depression in the world. It feels like absolutely everything in life is pointless, not to mention I’ve also lost my faith in God as I thought there’s people going through hell like this and worse, and he just doesn’t do anything to help.
 
Its the HARDEST THING EVER! Beeing dead but alive. Im 46, i have experience in life. I think its one of the hardest thing on planet for sure. Im 12 mnth off, i thought im improving, but im not when i think about it better, im just no longer zombie and i can cry. Idk now much longer i can take torture.. Not worth living. I still have hope, i know lots of people started recovering after a year, yar and a half, and even 2 yrs, but im slowly loosing hope. My kids are the ones for who i fight, if i dont have them idk where whould i be. Any support its gonna get better? Can we heal from this poison?
 
are you currently taking any medications?! 12 months is a big milestone! If I can give you some advice, now that you've started crying again, it means that your feelings are unblocking, try to feed positive thoughts and not negative ones, unblock dopamine by doing physical exercise and listening to music that gives you motivation, I've always resumed between 8 and 14 months, but you have to do your best, the first 15 days of exercise will be hard but if you can keep up the pace and continue then it will get better
 

- YouTube

Bekijk je favoriete video's, luister naar de muziek die je leuk vindt, upload originele content en deel alles met vrienden, familie en anderen op YouTube.
www.youtube.com www.youtube.com
 
bojana said:
Its the HARDEST THING EVER! Beeing dead but alive. Im 46, i have experience in life. I think its one of the hardest thing on planet for sure. Im 12 mnth off, i thought im improving, but im not when i think about it better, im just no longer zombie and i can cry. Idk now much longer i can take torture.. Not worth living. I still have hope, i know lots of people started recovering after a year, yar and a half, and even 2 yrs, but im slowly loosing hope. My kids are the ones for who i fight, if i dont have them idk where whould i be. Any support its gonna get better? Can we heal from this poison?
Click to expand...
It is hard, but you got this. Have faith, think about yours family and how far you've got. I'd read success stories, it will happen to you.
 
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