sekio
Bluelight Crew
I'm spitballing here but cocaine, being an alkaloid, should form salts with all sorts of acids, not just HCl.
Cocaine base 303.353 g/mol
Fumaric acid 116.07 g/mol
To form cocaine fumarate presumably you need 2:1 molar ratio of cocaine:fumarate.(So, 606.6d cocaine base and 116g fumaric acid, or 191mg fumaric acid per 1000mg cocaine base.
To form the hemifumarate use 1:1 instead. or 303.3g cocaine to 115g fumaric acid, pt 382 mg fumaric acid per 1000mg.
Prepare the salt by dissolving the cocaine base in diethyl ether or anhydrous acetone to make one solution, and the fumaric acid in ether or acetone to form a second solution. Then mix the two solutions and place in the freezer, collecting the precipitate of cocaine (hemi)fumarate.
You could also use eg. maleic acid, succinic acid, ascorbic acid (vitamin C), citric acid, and others if you adjust for the molecular weight of the acid used, and the number of acidic protons (citric has 3 acidic protons instead of 2, and ascorbic has 1)
Or you can also just mix the acid and cocaine base in water and heat to dissolve, although the yield may be lesser due to some hydrolysis of cocaine to benzoylecgonine. This is what is normally done to make crack injectable (using ascorbic acid in excess usually)
Cocaine base 303.353 g/mol
Fumaric acid 116.07 g/mol
To form cocaine fumarate presumably you need 2:1 molar ratio of cocaine:fumarate.(So, 606.6d cocaine base and 116g fumaric acid, or 191mg fumaric acid per 1000mg cocaine base.
To form the hemifumarate use 1:1 instead. or 303.3g cocaine to 115g fumaric acid, pt 382 mg fumaric acid per 1000mg.
Prepare the salt by dissolving the cocaine base in diethyl ether or anhydrous acetone to make one solution, and the fumaric acid in ether or acetone to form a second solution. Then mix the two solutions and place in the freezer, collecting the precipitate of cocaine (hemi)fumarate.
You could also use eg. maleic acid, succinic acid, ascorbic acid (vitamin C), citric acid, and others if you adjust for the molecular weight of the acid used, and the number of acidic protons (citric has 3 acidic protons instead of 2, and ascorbic has 1)
Or you can also just mix the acid and cocaine base in water and heat to dissolve, although the yield may be lesser due to some hydrolysis of cocaine to benzoylecgonine. This is what is normally done to make crack injectable (using ascorbic acid in excess usually)