Diet Weight loss drugs

muaddib666 said:
orlistat, naltrexone and buproprion combo, semaglutide
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you think a synthetic enzyme-inhibitor that prevents fat absorbtion is a "safer" option for weight-loss than the body's own thyroid hormones, which most people are deficient in and the lack of which is probably the most important thing in weight management..?
 
Lol1976 said:
I had a gastric sleeve done 5 months ago. Best thing i ever did, wish i did it earlier, ive lost 30kg with 10 left to go.
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But that should be a last resort for most people. My girl had it done too but she had been trying for many years and lost 50 lbs but couldn’t get past that.

Aren’t there weight loss drugs that are stimulants that are still in existence? I have taken a few in my time but I took them recreationally.
 
HOOH said:
you think a synthetic enzyme-inhibitor that prevents fat absorbtion is a "safer" option for weight-loss than the body's own thyroid hormones, which most people are deficient in and the lack of which is probably the most important thing in weight management..?
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First of all we are talking about T3 here not T4, if you have a deficiency it can usually be fixed with much safer T4. A too high dose of exogenous T3 can cause the symptoms of hyperthyroidism so high blood pressure, ultra rapid heartbeat etc. Do you really want someone who is already obese and has high blood pressure to take a medication that will raise their BP even more and possibly cause them a fatal stroke?

That is the reason why T3 is never prescribed to obese patients and why more stimulants like DNP and amphetamines are usually avoided too in favor of treatments that are less likely to literally kill the patient. Risk vs reward and all that.
T3 is used by bodybuilders on anabolics to cut before a show, if you are not on anabolics this stuff is highly catabolic and you will lose muscle tissue like crazy.
Pick your poisons but pick them well.
 
Juicewrldfan said:
But that should be a last resort for most people. My girl had it done too but she had been trying for many years and lost 50 lbs but couldn’t get past that.

Aren’t there weight loss drugs that are stimulants that are still in existence? I have taken a few in my time but I took them recreationally.
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  • phentermine
  • benzphetamine
  • diethylpropion
  • phendimetrazine
But only for short bursts of time while under medical supervision.
 
muaddib666 said:
First of all we are talking about T3 here not T4, if you have a deficiency it can usually be fixed with much safer T4.
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The problem with T4 is that many people have problems converting it into T3, hence why hypothyroidism symptoms often remain uncorrected even when one is "taking thyroid."
muaddib666 said:
A too high dose of exogenous T3 can cause the symptoms of hyperthyroidism so high blood pressure, ultra rapid heartbeat etc. Do you really want someone who is already obese and has high blood pressure to take a medication that will raise their BP even more and possibly cause them a fatal stroke?
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You said it yourself: too high dose. A high blood pressure might not be a good thing for someone obese, but neither is the metabolic hibernation they are otherwise in. A high heart rate, something related to this, might actually be beneficial.
muaddib666 said:
T3 is used by bodybuilders on anabolics to cut before a show, if you are not on anabolics this stuff is highly catabolic and you will lose muscle tissue like crazy.
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T3 is not catabolic, it only increases catabolism when the scientists are retarded about it: of course increased calorie requirements increase the amount of catabolism when measured by time (e.g. in a week), what one should be looking at instead is whether it increases muscle loss relative to fat loss. This does not seem to be the case.
 
HOOH said:
The problem with T4 is that many people have problems converting it into T3, hence why hypothyroidism symptoms often remain uncorrected even when one is "taking thyroid."

You said it yourself: too high dose. A high blood pressure might not be a good thing for someone obese, but neither is the metabolic hibernation they are otherwise in. A high heart rate, something related to this, might actually be beneficial.

T3 is not catabolic, it only increases catabolism when the scientists are retarded about it: of course increased calorie requirements increase the amount of catabolism when measured by time (e.g. in a week), what one should be looking at instead is whether it increases muscle loss relative to fat loss. This does not seem to be the case.
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Well in the bodybuilding community it is avoided because it's seen as excessively catabolic compared to similar(!) compounds. Theres also many reports of the substance making the user ravenously hungry which will likely make it ineffective when used to treat obesity. I think stimulant drugs that also surpress hunger more effectively would be a better choice, unless you are T3 deficient, that is.
 
muaddib666 said:
Well in the bodybuilding community it is avoided because it's seen as excessively catabolic compared to similar(!) compounds. Theres also many reports of the substance making the user ravenously hungry which will likely make it ineffective when used to treat obesity. I think stimulant drugs that also surpress hunger more effectively would be a better choice, unless you are T3 deficient, that is.
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yeah stims are def the way to go as far as hunger suppression goes, but the thing is that T3 just increases metabolism, of course you'd want that for weight loss, the increase in appetite isn't a real increase in appetite, since your energy expenditure goes up.
 
HOOH said:
yeah stims are def the way to go as far as hunger suppression goes, but the thing is that T3 just increases metabolism, of course you'd want that for weight loss, the increase in appetite isn't a real increase in appetite, since your energy expenditure goes up.
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If you eat more or the same as your new energy expenditure you did nothing except now surpressing your thyroid for no added benefit while stims also increase energy expenditure therefore i see no reason to ever advocate for t3 when not deficient, cost/benefit just does not add up.
 
muaddib666 said:
If you eat more or the same as your new energy expenditure you did nothing except now surpressing your thyroid for no added benefit while stims also increase energy expenditure therefore i see no reason to ever advocate for t3 when not deficient, cost/benefit just does not add up.
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increased metabolism = increased rate of lipolysis = faster fat-loss

i don't really advocate T3 for weight loss either though, I mean I advocate T3 for everything and certainly it would help obese, metabolically-fucked people, but I don't think it should be restricted to that or viewed as a weight loss — though its certainly superior at that when compared to Orlistat or Semaglutide or any of the other drugs which the mere existence of exposes the schizophrenia of medicinal chemistry in 2023.
 
I've not known of anyone in the U.S. ever get prescribed these. I wonder if it's even in the market or no longer sold?

I was just speaking to someone about his use of apple cider vinegar pre meal and he said it's effective along with diet and exercise. I've seen his before and after pics in person so not just some online guy. I'm probably going to try this route and see what happens.

muaddib666 said:
  • phentermine
  • benzphetamine
  • diethylpropion
  • phendimetrazine
But only for short bursts of time while under medical supervision.
Click to expand...
 
muaddib666 said:
orlistat, naltrexone and buproprion combo, semaglutide
Click to expand...
Bupropion I've tried as an anti depressant but are you saying to take all 4 medications at once? I'm not diabetic so I'm cautious on taking anything for diabetes like semaglutide.
 
ongos said:
I've not known of anyone in the U.S. ever get prescribed these. I wonder if it's even in the market or no longer sold?

I was just speaking to someone about his use of apple cider vinegar pre meal and he said it's effective along with diet and exercise. I've seen his before and after pics in person so not just some online guy. I'm probably going to try this route and see what happens.
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Nah phentermine is prescribed here but you have to go to a weight loss clinic where I live. Usually it’s a sketchy dr just trying to make money and knows what some of us really want it for.

Actually, one just got raided not long ago where I live.

This is dated last year.

www.drugs.com

Phentermine: Drug Uses, Dosage & Side Effects - Drugs.com

Phentermine is an appetite suppressant used together with diet and exercise to treat obesity. Learn about side effects, interactions and indications.
www.drugs.com www.drugs.com
 
A schedule 4 stimulant is odd don't you think? I guess it feels like Modafinil, another schedule 4 medicine that can be bought easily online yet phentermine isn't as widely available online.

There's an otc decongestant called phenylpropanolamine that is also used for weight loss but I haven't seen it sold as is but usually as a combo with another medicine for cough and cold (in the Philippines anyway).

Juicewrldfan said:
Nah phentermine is prescribed here but you have to go to a weight loss clinic where I live. Usually it’s a sketchy dr just trying to make money and knows what some of us really want it for.

Actually, one just got raided not long ago where I live.

This is dated last year.

www.drugs.com

Phentermine: Drug Uses, Dosage & Side Effects - Drugs.com

Phentermine is an appetite suppressant used together with diet and exercise to treat obesity. Learn about side effects, interactions and indications.
www.drugs.com www.drugs.com
Click to expand...
 
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ongos said:
Bupropion I've tried as an anti depressant but are you saying to take all 4 medications at once? I'm not diabetic so I'm cautious on taking anything for diabetes like semaglutide.
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No either orlistat
or naltrexone and buproprion combo
or semaglutide

Otherwise if you are in good cardiovascular health skip all this crap and go straight to stimulants and make sure you keep monitoring your vitals.
 
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