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🌟🌟 Social 🌟🌟 PD Social Thread 2022-2025 v. Year of the Phenethylamine

Oh man guys, i went to get my Methadone today and they said your done yesterday and today i dont get dosed. So here goes nothing boys, kinda works out now that i took the large dose of Memantine cuz it should push me through this period. Probably gonna dose on the heavier side every few days maybe drop to 20mg days for two and then on the third shoot for 100-140mgs. Im gonna power thru this shit and finally be free.

Talked with my work yesterday and im using up all of my sick time and will get half a weeks pay, and then my full week for the last so my check should still be pretty decent during this time away. Obviously im gonna have to not be spending too much money, thankfully we get three free meals at the halfway eachday and the food isnt great but its better than jail obviously. Just had a cup of Black Tea and Bagel w/ Cream Cheese it was pretty delicious.

Think im starting to feel the Memantine building already, its gonna be an eventful day for sure. Going to listen to alot of music and also for christmas i was given the entire collection of The Boys comic books, all six of the omnibus so its a ton of reading.

7-ate-9-comics-comic-the-boys-1-glenn-fabry-virgin-variant-ltd-to-250-37435878998242.jpg



My girlfriend is the best 😍
 
Im so high right now its bananas, have this shit eating grin plastered across my face. When we just in group before i felt like i was about to melt down into a puddle on the floor. Oh boy, and my boss is giving me 20hrs pay this week off so that is a nice treat as well.

Looking forward to when the induce the Bupe at the end of the week, with the Memantine obliterating my tolerance i will have a head full of fresh receptors.

Im gonna be cooking that day for sure 😛
 
Gonna have to finish that interview with Nichols. Thanks for posting.
Something struck me in the intro. He's working on a molecule that would covalently bind to the 5ht2a receptor. Now, I realize this is to study the structure of the receptor in its bound/active state. But I wonder what it will be like when one of you gets their hands on some and doses it.
Would the effects be severe and possible death, or would it be possible to dose low enough that you don't ruin all of your receptors but you still have a presumably wild trip from the covalent bonds at a small fraction of your receptors?
 
porkstock said:
He's working on a molecule that would covalently bind to the 5ht2a receptor. Now, I realize this is to study the structure of the receptor in its bound/active state. But I wonder what it will be like when one of you gets their hands on some and doses it.
Would the effects be severe and possible death, or would it be possible to dose low enough that you don't ruin all of your receptors but you still have a presumably wild trip from the covalent bonds at a small fraction of your receptors?
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You‘re thinking of CE-LAD which has a chloroethyl-group at N6 which forms an aziridinium ion that alkylates the receptor. Idk if it would be extraordinarily dangerous considering there‘s plenty of drugs that covalently bind to certain receptors and they usually just grow back after a few days and displace the old ones but definitely sth. to be careful about. I wonder how long the duration of action would be? I wouldn‘t want to be the first one to find out, that’s for sure lol. I would also like to see how a fluoroethyl-group would play out in that position. According to Wikipedia "FLUOROETH-LAD" has been synthesized before but I haven‘t looked into it.
 
Still processing that and literally can't think of more to say yet =\ but in other news, coincidentally Cosmic Charlie, I quit taking my methadone today too. Had tapered down to 2.5mg/day, with plans to finish out at 1.25mg/day before quitting, but woke up today and couldn't find my last few 10mg tablets. I have the empty bottle tho. No idea what could have happened to them... I never have company over... So incredibly weird. Hopefully withdrawals won't be too bad. Been on opiates since before beating cancer, so about 4-5 years now!
 
pharmakos said:
Still processing that and literally can't think of more to say yet =\ but in other news, coincidentally Cosmic Charlie, I quit taking my methadone today too. Had tapered down to 2.5mg/day, with plans to finish out at 1.25mg/day before quitting, but woke up today and couldn't find my last few 10mg tablets. I have the empty bottle tho. No idea what could have happened to them... I never have company over... So incredibly weird. Hopefully withdrawals won't be too bad. Been on opiates since before beating cancer, so about 4-5 years now!
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Good to hear from you man, was thinking of you the other day.

I just saw today my co-worker friend hearing that his wife has cancer, the look in his eyes. made me cry too.
 
Psychestim said:
You‘re thinking of CE-LAD which has a chloroethyl-group at N6 which forms an aziridinium ion that alkylates the receptor. Idk if it would be extraordinarily dangerous considering there‘s plenty of drugs that covalently bind to certain receptors and they usually just grow back after a few days and displace the old ones but definitely sth. to be careful about. I wonder how long the duration of action would be? I wouldn‘t want to be the first one to find out, that’s for sure lol. I would also like to see how a fluoroethyl-group would play out in that position. According to Wikipedia "FLUOROETH-LAD" has been synthesized before but I haven‘t looked into it.
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Sounds like some shit the CIA would like to lace acid with.
 
Wife left town for the week, just me and the pets. Played some groovy music and played with the dog. Bought a new shovel to dig a trench around the back of my house and try to get the dirt to stop washing up onto the siding every time it rains. Gonna just do house/yard work for the week and finish unpacking.

Took about 20mg of d8-thc tincture, got a sixer I'm about to start on and loads of frozen food. Just gonna binge movies tonight, start yard work tomorrow. I found so... so, so many vines growing into the siding that were simply cut and painted over, this house gets worse the deeper I look! But, it is my own, my house, my name is on the deed and I can do (almost) anything I want to it. Keeping that in mind I've felt pretty happy in recent days. Working outside a lot more and just feel, at peace. My town is so, so small, about the size of Twin Peaks if the network had let Lynch put the size he wanted to on the sign. And it feels like Twin Peaks in a lot of ways. Lots of big old trees and hills as far as the eye can see.

And I fucking love it :) we are going to wrack up lots of money fixing this ol' house but by Jove it's ours and finally I have peace and quiet!
 
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That's awesome man! I'm really glad you have some peace of mind. And like I said in another thread, doing work on your house is an incomparable sort of satisfaction. You can learn how to do so many things and if you do them yourself, it's so much cheaper.

I am going to have to replace my siding sometime in the next few years... I got a quote from someone for over $40,000. But my friend built his own house, and if I get the materials, he'll help me do it. It'll cost a handful of thousands instead of 40. And it'll feel awesome to have done it myself.

I also have a much bigger project... I need to winch the house up and properly foot it, build a retaining wall... that will require hiring someone and will probably cost 50 grand. Unless I make big money in crypto in a few years in the next bull run, it will require waiting until I have more equity and refinancing again.

But then, I'll be able to frame out what is current the carport, and finish out the garage/basement plus the carport area into livable space, with a separate entrance. I can put a closet in there, and a bathroom, and my house will grow from 1300 dquare feet, 2 bed/2 bath, to !2100 square feet, 3 bed/3 bath. And I could AirBnB out the new area if I wanted, my location is ideal (10 minutes from downtown, 4 minutes from the Blue Ridge Parkway). If I put a small kitchen in there, I could charge $300+ per night. That would be nuts. It would pay for itself pretty fast.

pharmakos said:
Just found out BLer thou passed away (Malaria Flynt on Facebook, which is where he spent most of his time the last few years it seemed). No more details yet. =\
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Oh no, Thou died? :( I'm sorry that such awful news brought you back... but I'm glad to see you, regardless. How have you been, man?
 
pharmakos said:
Still processing that and literally can't think of more to say yet =\ but in other news, coincidentally Cosmic Charlie, I quit taking my methadone today too. Had tapered down to 2.5mg/day, with plans to finish out at 1.25mg/day before quitting, but woke up today and couldn't find my last few 10mg tablets. I have the empty bottle tho. No idea what could have happened to them... I never have company over... So incredibly weird. Hopefully withdrawals won't be too bad. Been on opiates since before beating cancer, so about 4-5 years now!
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glad to see you still kicking around. how's your health?
 
Found out one more detail about Thou... His mom found him on Christmas morning. Still not sure about cause but I worry, because he knew his limits. The reason he knew his limits is because of how often he pushed himself right up to them but yeah, the Christmas timing, just =\

Re: health, had my 2.5 year checkup recently, still some funny spots in my abdomen that could or could not eventually prove to be cancerous but nothing growing so still in remission.

Quitting methadone was easier than I figured, I guess dropping off from 2.5mg made it pretty easy. Four days since my last dose.
 
I hope the cancer stays away man. And that's fucking awesome about methadone! I would have expected you'd be withdrawing by now... 4 days after 2.5mg, it will have totally cleared your system by now and then some, at such a low dose. That's super encouraging for me, because I'm on suboxone, unfortunately, and working to reduce. I dropped to 8mg per day recently and I expect to be able to drop to 2mg/day relatively quickly, but after that it gets hard. I am going to do a slow taper of 10% per week, I think. Which gets VERY slow as the dose goes down, but I have the pills and a milligram scale so I can crush them up into a powder and weigh very precise doses. I am planning to go down all the way to 0.05mg... considering they prescribe 0.1 to 0.3mg for pain, it's still a totally active dose. I want to make the jump as painless as possible because opiate withdrawals tend to make me completely unable to function and the last time I tried to go cold turkey, my work was noticing something was wrong and I relapsed largely because I couldn't function. So I need to avoid that. But I can't just take kratom or something because kratom, every time, gets me rapidly into dosing repeatedly throughout the day and always being on the verge of, or in, withdrawals. So I really need to be able to just jump off suboxone and not use any opioid at all.
 
Man i wanna be free from it all also, but i just dont think that is in the cards right now. They are going to be giving me 4mgs of Bupe on either monday or tuesday, so im gonna have to just ride this out tlll then. Im fully up on the 100mgs of Memantine right now, it makes the withdrawal symptoms so minor its like night and day.

Even the RLS which is the only one that was giving me trouble isnt much of an issue right now. Hopefully i will be able to sleep tonight gotta wait and see what happens. Just laying around and listening to podcasts i think im gonna make some coffee or something i could go for a hot beverage. Ive eaten breakfast and lunch today which is good. Deff having a better day then yesterday. Sleep is pretty critical at this point i think.
 
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