Mental Health Coming off Invega (Paliperidone, Xeplion) injections v 6.0

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Have you lost any of your weight yet? I’m at 114lbs on a good day
I gained a total of 40 pounds through the 3 years on/off the injection and have managed to lose 30 pounds. But the last 10 pounds doesn’t seem to budge, I’ve tried everything from exercise to dieting to keto and strength training. I’m low key losing hope to get to my pre-invega weight but I guess the last option would be fasting. It’s just difficult to do.
 
It’s impossible for “more” Invega Sustenna to be released in your system as time goes by I don’t know why people keep saying this. Invega Sustenna is in your blood stream and in your blood levels. That’s what my doctor explained to me, that’s why they give you the two loading doses in the beginning to get enough in your blood stream to alter your brain. I just talked to a guy on Reddit who is two years and four months off Invega Sustenna and not on any other drugs and hasn’t recovered his sexual dysfunction or anything yet (he’s not on any other antipsychotics)
I agree. The injection affects everyone differently. I don’t think you can really compare progress because everyone’s brain chemistry is so unique.
I have recovered from the injection 3 times and each time I have a slightly different progress timeline so I can only imagine how different another persons progress would be compared to mine.
I had very high libido about 5 months off the first time I recovered for some reason, recovered libido about 6 months off the second time, and am now 9 months off and have very low libido.
I would just suggest being patient and waiting at least 1.5-2 years before looking back and seeing progress, because this withdrawal journey is not the same for everyone.
 
I agree. The injection affects everyone differently. I don’t think you can really compare progress because everyone’s brain chemistry is so unique.
I have recovered from the injection 3 times and each time I have a slightly different progress timeline so I can only imagine how different another persons progress would be compared to mine.
I had very high libido about 5 months off the first time I recovered for some reason, recovered libido about 6 months off the second time, and am now 9 months off and have very low libido.
I would just suggest being patient and waiting at least 1.5-2 years before looking back and seeing progress, because this withdrawal journey is not the same for everyone.
How many injection did you have the 3 Times?
 
It’s impossible for “more” Invega Sustenna to be released in your system as time goes by I don’t know why people keep saying this. Invega Sustenna is in your blood stream and in your blood levels. That’s what my doctor explained to me, that’s why they give you the two loading doses in the beginning to get enough in your blood stream to alter your brain. I just talked to a guy on Reddit who is two years and four months off Invega Sustenna and not on any other drugs and hasn’t recovered his sexual dysfunction or anything yet (he’s not on any other antipsychotics)
I'm almost 5 months off and its barely getting better with my sexual dysfunction.
At that rate it will probably take me years, if at all to recover sexually from this poison.
So frustrating, it is unbelievable the kind of damage that was done to us.
 
Does that mean that antipsychotics were doing nothing for my bipolar depression? Or making it worse (that’s what it felt like)? Or am I misunderstanding?
That's roughly correct. Big Pharma has been trying to push some antipsychotics as depression treatment adjuncts but the evidence does not really support this. For your bipolar depression, your options within psychiatry are bipolar meds and antidepressant meds.

I know I talk about this a lot but will I recover sexually? I've been off invega for almost a year but was switched onto haldol for a couple months then abilify. My penis feel numb and no pleasure when masturbating. I just want to feel pleasure when masturbating and having sex again.

Many people on here seem to recover from all adverse side effects within 4-8 months, but you are in a severe category, like myself. I too have had your same problem sexually--it's terrible--for a whole year now. We are faced with three possibilities: it could be permanent; it could have a cure (that needs to be researched, which I am in the process of doing and networking with researchers and doctors to do); it could take time, maybe months to a year or 2 years.
 
4 months off invega and it feels like I’m getting worse anybody experience this? I felt like at 3.5 months I was more recovered then I am now maybe it’s withdrawal or more paliparadone being released in my system.
I think around that time is when withdrawal really sets in, I’m at month 5 and feel worse than before in a lot of ways.
 
Yes you will I couldn’t feel substances in the first month off the shot but now I can although I don’t take substances often so I have a low tolerance I’m 4 months off, you keep asking that same question though if you can’t get high anyway I’d suggest taking a t break and maybe finding a new hobby there’s more to life then getting high.
Did you get the Invega or Xeplion shot?
 
I think around that time is when withdrawal really sets in, I’m at month 5 and feel worse than before in a lot of ways.
I took a blood test a few weeks ago and I was at 5.2ng ml of paliparadone which is pretty low so at this point my brain is probably adjusting to a state more like homeostasis therefore I’m having withdrawals even though we both feel like shit rn it’s a good thing cause we are adjusting so we might see big improvements soon. I took the paliparadone pill for 2 weeks a month after getting the shot quit that and got pretty bad withdrawals from it I felt even shittier then I did on the pills but a month after I stopped the pills I felt way better.
 
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Here is one positive way to look at it - antipsychotics all antagonise and in theory would all increase dopamine receptor density, primarily at d2 which is that ticklish motivating receptor. You have to be careful because you are at high risk of slipping into psychosis from overactive dopamine activity. It will naturally make you extremely fidgety. I too have been in quite a few drug induced psychoses this last year. I had never been to a psych ward until last year, and ended up there 5 times..it was quite the doozy. I didnt know i was in a psychosis the first time, and it took 5 days of aimlessly wandering around dallas putting my life at risk hallucinating before my family and girlfriend got me into a detox center..all of my episodes after that, i was able to predict and somewhat discern hallucinations from reality, but MAN was it hard and damn near impossible.
 
The doctor gave me seroquel and gabapentin with some ativan, and i was BRAND spankin' new! Works every single time for psychosis --- for me. Thankfully.
 
That's roughly correct. Big Pharma has been trying to push some antipsychotics as depression treatment adjuncts but the evidence does not really support this. For your bipolar depression, your options within psychiatry are bipolar meds and antidepressant meds.

I actually do find lurasidone/latuda helpful as an anti depression medication for my bipolar 1. I had a depressive episode for maybe 3+ months and within weeks of starting the medication I was back to normal. Basically all typical anti depressant medication causes me to be manic, and I have in the past had a bad habit of discontinuing mood stabiliser medication, so I prefer the combination I have now (lurasidone/valproate) to anything else I've ever had.

Everyone has different brain chemistry and suggesting that antidepressants are the best/correct way to treat bipolar is not universally correct.

There is a pretty significant amount of evidence I have seen with success after lurasidone for others with bipolar.
 
That's roughly correct. Big Pharma has been trying to push some antipsychotics as depression treatment adjuncts but the evidence does not really support this. For your bipolar depression, your options within psychiatry are bipolar meds and antidepressant meds.



Many people on here seem to recover from all adverse side effects within 4-8 months, but you are in a severe category, like myself. I too have had your same problem sexually--it's terrible--for a whole year now. We are faced with three possibilities: it could be permanent; it could have a cure (that needs to be researched, which I am in the process of doing and networking with researchers and doctors to do); it could take time, maybe months to a year or 2 years.
I've unfortunately been off of Invega for 2 years and four months and haven't made any substantial progress. I still have yet to recover my emotions, creativity, cognition, energy, and sexuality. I've went off of ALL meds for 2+ years . My psychosis was drug induced (a mix of adderall, shrooms, weed, and MDMA that turns out was laced with meth), so perhaps Invega harms people more who don't actually have a schizophrenic illness. I know that it's not just in my head because I just literally can't cry or feel anything, no matter how tragic something is (family member dying, sad movies . music). Additionally, my semen is still completely clear/watery. You can't psychosomatisize/ overthink yourself into remaining infertile.

Something is seriously messed up with my body and mind. I am only in my early 20s and my life feels completely over.

I go to an Ivy League school, was at the top of my class, had a loving partner and great friends and it's all vanished. I can't connect with people. I never laugh, lost my sense of humor, which was one of the core ways in which I'd relate to people.

I'm giving myself one more year to hopefully recover and if not I will probably be committing suicide.

I stayed away from ALL meds for 2 years, and recently tried (within the last four months) Trintellix, Wellbutrin, and Parnate, each of which did nothing for my recovery (other than Wellbutrin, but only momentarily and then I kept having to raise my dose, which just simply isn't sustainable).
 
That's roughly correct. Big Pharma has been trying to push some antipsychotics as depression treatment adjuncts but the evidence does not really support this. For your bipolar depression, your options within psychiatry are bipolar meds and antidepressant meds.



Many people on here seem to recover from all adverse side effects within 4-8 months, but you are in a severe category, like myself. I too have had your same problem sexually--it's terrible--for a whole year now. We are faced with three possibilities: it could be permanent; it could have a cure (that needs to be researched, which I am in the process of doing and networking with researchers and doctors to do); it could take time, maybe months to a year or 2 years.
I believe a cure is possible if time doesn't fix it, please keep us updated on your efforts finding a cure
 
Thx! I’m not manic, but I am extremely anxious, and obsess about losing my mind again, so I don’t think psychedelics would be a good idea for me. LSD use is what caused me to go manic for the first time when I was first diagnosed.
You are absolutely wise and correct to avoid psychedelics if you suffer from severe anxiety AND if LSD is what caused your initial psychosis. Please avoid psychedelics, and it would probably be best to avoid all illicit substances while you are recovering as well.

4 months off invega and it feels like I’m getting worse anybody experience this? I felt like at 3.5 months I was more recovered then I am now maybe it’s withdrawal or more paliparadone being released in my system.
That is odd and I'm sorry to hear you're not continuing to feel better. Are you engaging in any healthy lifestyle activities, healthy diet, good sleep regime, regular exercise, regular face to face socialisation with friends and family, etc? All of those things can help immensely in recovery.
 
You are absolutely wise and correct to avoid psychedelics if you suffer from severe anxiety AND if LSD is what caused your initial psychosis. Please avoid psychedelics, and it would probably be best to avoid all illicit substances while you are recovering as well.


That is odd and I'm sorry to hear you're not continuing to feel better. Are you engaging in any healthy lifestyle activities, healthy diet, good sleep regime, regular exercise, regular face to face socialisation with friends and family, etc? All of those things can help immensely in recovery.
i posted earlier and figured out why I’m not feeling better I got to the bottom of it and yes I have a healthy diet good sleep and regular exercise ever since my withdrawals increased I can’t do as much exercise like lifting and running but I still take long walks, socially I’m not doing well I’m not really motivated to go out or anything I used to be a really social guy but invega made me a shell of the person I was before however I’m going back to school in January and may start working so that’ll help.
 
I've unfortunately been off of Invega for 2 years and four months and haven't made any substantial progress. I still have yet to recover my emotions, creativity, cognition, energy, and sexuality. I've went off of ALL meds for 2+ years . My psychosis was drug induced (a mix of adderall, shrooms, weed, and MDMA that turns out was laced with meth), so perhaps Invega harms people more who don't actually have a schizophrenic illness. I know that it's not just in my head because I just literally can't cry or feel anything, no matter how tragic something is (family member dying, sad movies . music). Additionally, my semen is still completely clear/watery. You can't psychosomatisize/ overthink yourself into remaining infertile.

Something is seriously messed up with my body and mind. I am only in my early 20s and my life feels completely over.

I go to an Ivy League school, was at the top of my class, had a loving partner and great friends and it's all vanished. I can't connect with people. I never laugh, lost my sense of humor, which was one of the core ways in which I'd relate to people.

I'm giving myself one more year to hopefully recover and if not I will probably be committing suicide.

I stayed away from ALL meds for 2 years, and recently tried (within the last four months) Trintellix, Wellbutrin, and Parnate, each of which did nothing for my recovery (other than Wellbutrin, but only momentarily and then I kept having to raise my dose, which just simply isn't sustainable).
Sorry too hear you haven’t recovered yet but hang in there there was a guy named aiden21 who recovered after 4 years, Guys don’t feel hopeless reading a post like this a case of someone not recovering in 2 years 4 months is extremely rare.
 
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