I'm reaching the end of my rope

[S-Dog]

Smoking spice is definitely going to make things worse not better

I use extracts like delta 8, not synthetics. extracts have issues also but nothing like spice

 

[mdaniel80]

Don't take any drugs, start exercising and meditate. The change will not come instantly, but the improvement will follow. If you are really depressed, out of every crappy antidepressant out there, Bupropion is the least damaging if you want to go to a psychiatrist. Or you could try phenotropil, which Russians used to treat every ill back in 2010.

phenylpiracetam has gotten a bit hard to obtain. LOTS of bunk out there now

 

[mdaniel80]

I use extracts like delta 8, not synthetics. extracts have issues also but nothing like spice

Delta 8 is synthetic. It only occurs in cannabis plants in trace amounts. Synthetic processing is necessary to make effective product.

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[Skorpio]

Delta 8 is synthetic. It only occurs in cannabis plants in trace amounts. Synthetic processing is necessary to make effective product.

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It's structure and pharmacology (ie partial agonism) are much more similar to those of thc than the components of spice. I think that is what S-dog was implying by that dichotomy.

 

[mdaniel80]

It's structure and pharmacology (ie partial agonism) are much more similar to those of thc than the components of spice. I think that is what S-dog was implying by that dichotomy.

Maybe. Just clarifying that D8 is not a natural extract when in consumable products.

 

[S-Dog]

It's structure and pharmacology (ie partial agonism) are much more similar to those of thc than the components of spice. I think that is what S-dog was implying by that dichotomy.

The key thing about Delta-8 (and similar products) is, they are what they are. "spice" is no specific chem. it changes all the time based on laws and whatever's available so you never actually know what you're getting. The same product could actually be two totally different drugs. But Delta-8 is what it says on the label. again, not that it's perfect but it's consistent and in the very least is a naturally occurring cannabinoid even if it's created synthetically. Spice is purely synthetics

 

[Skorpio]

Natural and synthetic really don't matter. What does is the action at the CB1 receptors. THC, and the new semi-synthetic isomers are partial agonists. This gives them a bit of a ceiling effect with regard to dosing, as they only activate the the receptor to some portion of maximum activation, regardless of the dose.

Noids like the jwh series and the other backbones tend to be full agonists are full agonists, which have no limits on dose-dependent receptor activation. This leads to mind melting panic attacks and hazardous overdoses.

Playing whack a mole to keep these things legal was frankly the worst development in drugs since somebody decided to cut heroin with fent.

 

[deficiT]

Why is it, the more I need help, the more I reach out, the more alone I am? I have no friends other than two online. I don't have a close relationship with anyone from my family and the only relationship i've ever had, fell apart after close to thirteen years. I've now been to three therapists and I hated every one of them. All three told me that they're "different" which I now know means "I'm exactly the same asshole you've been dealing with".

I am so deeply unhappy with myself and my life that I can't put it into words. I have little to no control over my emotions at this point. I'm either crying for hours or I'm so fucking angry that I feel like I'm going to have an aneurism.

The only thing that's helped is pot but it's illegal in my state so all I have are what ever trash cannabinoids are legal for smoke shops to carry which changes every other day. The only thing I know how to do is medicate myself into feeling nothing and I just have to hope what ever the smoke shops have this week will get the job done.

I'm immobilized with depression and still spiraling but the only thing any one has to say to me is either "other people have it worse" or "just smile more"

I can't keep going like this

I'm sorry you're going through this friend. Life has a way of punching down.

But I'll be your friend. Seriously. Hmu anytime, day or night. I've been through some shit fr and generally feel a lot of the same things you're referencing, but somehow keep persevering. And despite my worst thoughts and emotions, some days I wake up and things have actually gotten better for one reason or another.

Keep the faith and stay up brother.

 

[THECATINTHEHAT]

I very much doubt that the only thing that will help is pot. You would be in an extremely small bracket if that was true. I don’t doubt it may provide immediate symptomatic relief, but like other drugs (benzos are a good example) it’s use can also be a cause of those things it seems to cure when looked at in a wider time frame.

Ever tried taking multiple months off it? What else have you tried?

 

[mdaniel80]

The key thing about Delta-8 (and similar products) is, they are what they are. "spice" is no specific chem. it changes all the time based on laws and whatever's available so you never actually know what you're getting. The same product could actually be two totally different drugs. But Delta-8 is what it says on the label. again, not that it's perfect but it's consistent and in the very least is a naturally occurring cannabinoid even if it's created synthetically. Spice is purely synthetics

I disagree. D8 and these other "noids" are unregulated. There is no guarantee that "they are what they are". Im not advocating for regulation, but for harm reduction purposes it is important to understand that there may be "spice" in that headshop d8 pen. Its not a pure natural extract at all and may not even be pure synth d8

 

[S-Dog]

I very much doubt that the only thing that will help is pot. You would be in an extremely small bracket if that was true. I don’t doubt it may provide immediate symptomatic relief, but like other drugs (benzos are a good example) it’s use can also be a cause of those things it seems to cure when looked at in a wider time frame.

Ever tried taking multiple months off it? What else have you tried?

I never intended to say the ONLY thing that can help is pot. Only that I prefer it over getting tossed around the medical industry, wracking up enormous bills. I've been weening myself off and intend to step away from it for a while. The reason I don't just drop it outright is because I was getting extremely emotional when I tried so I just cut back a lot which has helped.

mostly what i think will actually help has nothing to do with drugs or shrinks. I just feel like I have to purpose