Nicotine is neuroprotective, there is also a bit of research suggesting it could be beneficial in the treatment of Parkinson's and, as you mentioned, Alzheimer's. I've also heard a bit about it being slightly effective in weight loss. I don't use nicotine often, but I do enjoy using it on occasion as a stimulant when trying to finish certain tasks. Can't really commend to it's use in depression/anxiety though, am curious to find out.
Vape pens are full of crap. There is no way that all of the shit in consumer products isn’t terrible for you. I’d love to be proved wrong, but… I dunno.
Yeah for sure, I predict in 10 years or less we’ll find out how bad they really are for you.
Oh yeah, cigarettes are nice until you realize the damage they do on your body, imo more than most psychoactive substances. But I loved mentol cigs as well! Was also smoking around one pack a day, which summed up to quite some research chemicals I could have bought with the same bucks. Never got appetite suppression nor an increase after quitting, and quitting wasn't too hard for me, just cravings for 1-2 weeks or so, and occasional cravings when seeing/smelling somebody else smoking. I actually like the smell of (fresh, old is ugly) tobacco smoke.
Dxm blocks the effects of smoking?
Yeah, nACh7 antagonists basically block any effect from nicotine even when they antagonize just one of the bunch of nicotinic receptors. But I might have been wrong about DXM, I just remembered that it hits this receptor as well but now as you're asking I've revisited its Wikipedia pharmacology page. I guess 15mg would be far too less, but it can't hurt to try it. But one thing is that dissociatives on their own do greatly potentiate the nicotine high and it all depends on the affinities and your genetics. The other two, bupropion which is used medically to aid with cessation of smoking, and memantine which I've tried extensively myself, are more reliable. 20mg (probably less) of memantine are enough to block nicotine.
