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What is wrong with the MDMA available today?

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According to the chart, ketamine looks more orange. There are a couple of other things that are yellow though.

The Pokeballs, the last good e I took was said to have some ketamine in them...

 
Look at the second set of reagent reactions, not the first. The color difference is more clear on the 2nd set. I want to know what the difference is in those two sets.

Me too, it’s always confused me how they put 15-30secs for both. My best guess is the darker/first picture is about 30secs and the second picture is soon after dropping the reagents.

The Pokeballs, the last good e I took was said to have some ketamine in them...


Pokeballs were ~90mg MDMA, ~20mg caffeine and 5-10mg ketamine if I remember right. Not enough K to feel orally but I bet it did change things slightly pharmacologically.

-GC
 
Here's a good paper on isomers. Just make a free account to read it.


Another abstract, saying that MDMA can change DNA


Abstract on tolerance


Interesting paper on CNS activity vs. slight chemical changes

 
Not sure if the paper is talking about analogs or slight molecular changes. It's a good read...


It is hoped that this review will bring attention to some often overlooked variables which can influence the pharmacological effects of clandestinely prepared drugs. First, that these drugs are usually impure and will predictably contain certain synthetic contaminants. Second, that the pharmacological/toxicological properties of the clandestinely manufactured drugs are dependent on the intended active component in addition to the synthetic contaminants. Finally, knowing these contaminants are present will help to better understand the medical consequences following abuse of these drugs.

Due to the numerous phenylalkylamine hallucinogens abused along with those having potential for abuse in the illicit drug market, it is useful to describe the general structure-activity relationships of these compounds as it relates to their hallucinogenic properties. This is facilitated by the excellent reviews that are currently available on hallucinogens.114,152,153 It is unique that extensive quantitative human data on these hallucinogenic phenylalkylamines are known and this can be attributed to the studies by Shulgin and coworkers. Briefly, the incorporation of a methoxyl(s) or methylenedioxy group or combination of these groups into the aromatic ring changes the activity of the phenylisopropylamine from being primarily stimulant to primarily hallucinogenic. The psychotropic potency of the compound depends not only on total density and location of substituents on the aromatic ring but also on the specific nature of the substituent. As is seen in Table III the 2,4,5-trisubstitution pattern gives compounds of optimal hallucinogenic activity. In all of the hallucinogens the 4-substituent is of major importance in that it can increase lipophilicity (increasing CNS penetration), provide resistance to oxidative metabolism and increase hydrophobic binding at the receptor. The nitrogen, two carbons from the aromatic ring, is required for activity and introduction of the methyl group alpha to the nitrogen increases activity over the ethylamine counterpart (this is due to both inhibition of metabolism at the nitrogen and increased lipophilicity). The alpha-methyl also introduces a chiral center in which the (R)-enantiomer is the more active hallucinogen.154 Generally, N-alkylation drastically attenuates the hallucinogenic activity. This is seen with the N-methyl and N-ethyl analogs of 3,4-methylenedioxyamphetamine in which they cause primarily stimulant activity while 3,4-methylenedioxyamphetamine acts primarily as a hallucinogen. Dialkylation, even in 3,4-methylendioxyamphetamine, abolishes hallucinogenic activity. The molecular mechanism responsible for the hallucinogenic effect of these phenylalkylamines is currently unknown. It is important to note that in all of these reviews, hallucinogenic activity is being evaluated and the other peripheral and CNS effects are not the focus of the review. Fatalities have not been reported with hallucinogens except for 4-methoxyamphetamine,135 4-bromo-2,5-dimethoxyamphetamine155 and 3,4-methylenedioxyamphetamine.156 Shulgin considers 4-methoxyamphetamine a "treacherous" drug to study in humans because of its steep dose-response curve. A therapeutic index of about 2.5 is suggested.114 When this drug was first available in the illicit market a number of deaths occurred throughout Canada and the United States. The toxic symptomatology which was very similar to amphetamine included agitation, convulsions, respiratory depression, hypertension and hyperthermia. The molecular mechanism of death is not known. The other hallucinogen associated with a human death, 4-bromo-2,5-dimethoxyamphetamine, appeared to be a relatively safe drug to abuse,114 however, at high doses it was observed to cause disorientation, cardiovascular distress and convulsive complications. The single death associated with this drug was at very low concentrations and based on both toxicological and pathological data it appeared to be due to an acute allergic reaction to the drug rather than its pressor effects.155 3,4-Methylenedioxyamphetamine although relatively non-toxic, at high doses has toxic responses similar to amphetamine toxicity.157,158 For all of the hallucinogens a variety of additional pharmacological effects in animal models are known since these effects were being measured to see if they could be used to accurately predict human activity as a hallucinogen. However, how these pharmacological effects in the animal models could be used to explain toxicological effects in humans has not been evaluated.
 
No, you posted the correct set. I am just a bit confused about why Drugs Data lists two different sets of reactions. What is the differentiating factor? They both say they were photographed between 15-30 seconds, but they look quite different from each other.
Me thinks it is the quantity of the drug.
The second sets contain less concentration of the drug.
It should just be the same reaction after a period of time. It's not consistent though. Here's one example where you can clearly see from the writing on the test film and the positioning of the droplets it's the same reactions, then there's one like this where from how the lab ID is written differently it's clearly different tests.
 
I too have examined and determined what Negi is saying. Some are the same and some are two different sample slides being tested. Why they change it up, I don’t know..

-GC
 
Take a look at the shadows of the black print and the hadwriting done by the marker. From the ink banding and the paralax of the shadows it is obvious that the ink is on top of a reusable glass overlay and the reagents are mixed with the drug sample under the glass. Most likely on a piece of paper or white cardboard..
 
On a note i can confirm those Jurassic park pills are complete magic we have them here atm and they are fucking amazing clean long strong loving roll. Proper dutch import.
 
yeah, they have a total of 260 mg mdma half of one of them is very good.

Can't help but notice that the colors on this pill look more like G_Chem's sample on the marquis, but it has the yellow for the mandelin reaction like my samples did. The mecke on this one is super blue.
 
madelin itself is a strong yellow color which will still show through once u swirl it around its important to see that its a dark blue in the first photo. The purity tests of the three samples done by people here shows low purity mdma.
 
madelin itself is a strong yellow color which will still show through once u swirl it around its important to see that its a dark blue in the first photo. The purity tests of the three samples done by people here shows low purity mdma.

That dark blue result is the Mecke. In the notes, they indicate that Mecke and Mandelin are switched.
 
That dark blue result is the Mecke. In the notes, they indicate that Mecke and Mandelin are switched.
yeah i see but the mandelin is still dark blue aswell with a small hint of yellow which would what its original color is depending on the strength of the color change indicates a level of purity while others will still be more yellower than this one,
 
yeah i see but the mandelin is still dark blue aswell with a small hint of yellow which would what its original color is depending on the strength of the color change indicates a level of purity while others will still be more yellower than this one,

Strength of reaction can’t be used to determine purity. Amount of material, density of material, etc all play into that.

Using reagents to look for purity only works if your testing pills, using the exact same amount of finely crushed material. Drugs Data doesn’t even crush up the material far as I can see.

Yea I remember countless times trying to find a way to determine purity with these reagents, it ain’t happening.. Typically pills create a stronger reaction to loose shard since it’s pre-milled easily dissolved product.

Also I can say without a shadow of doubt, the product I submitted is hell of a lot more pure than an ecstasy pill that probably contains about 50% lactose/magnesium stearate/filler.

-GC
 
Me, I only took MDMA crystals once , just 75 mg without tolerance and on an empty stomach. Never ever. I went out then to met a girlfriend and she was looking at me and told me - "please let us go home and you lay down on the sofa". She was already more experienced. It was so weird, my eyes were wide open, my body feeling was like i would puke but i don't. We lay on the sofa together and step by step this shitty bodyload feeling dissapeared but there was also no love feeling, nothing. And I could not bear having people around me, so i was very grateful to going home where it was cozy and my friend was here.

Ecstasy I tried 3 times or so and ONCE i had what you are talking about here: the ultimate love feeling for everybody and everything. It was half a pink adidas, I never got it again. The other two were also just half a pill, testet before (MDMA but who knows) and they were like i felt nothing. Because i took too less, but I thought no, i had THIS ONE experience and it will always be in my mind, never forget it. Since then I've never done MDMA.

JJ

P.S. the ADIDAS-PILL was testet with 120 mg MDMA, I took 60 mg and I think that is what i really like. Just a slight, nice feeling, loving the whole world. I could never ever imagine to take a pill that has 300 mg MDMA as i saw on checkit pillreports. What the fuck is then happening to you??
 
I have followed this thread for over a year. I have never posted on Bluelight or any other drug focused message board, and never was compelled to until now. However, after so much time spent on this thread, I do feel a desire to add my viewpoint.

Experienced roller. I am 35 now, and started in 2009. I have never "stopped", but am very very respectful of the drug. I am a working professional with a wife and 2 kids. My MDMA use is not known to many except close friends and my wife. With that said, my use is down to 2 x per year. Before that never more than 3-4 times a year. Guessing maybe 40-50 experiences total over 12 years. No binging. My personality is generally cautious regarding these things. I have experimented with single dosages between 120 to as high of a single dose at 220. I prefer 150 now. Typically redose with half of original dose at 1.5 hours.

My first experience in 2009, which is when a lot of folks started reporting bad MDMA, was the typical magical experience. All of the amazingness and self discovery that you would expect.

As someone who wouldn't know how to find a drug dealer if he was my next door neighbor, I was an early adopter of the darkweb and have been ordering product there since about 2012. I am very careful with my vendors and do lots of research as these experiences for me are few and far between. I do not want to waste them on bad product.

By around 2016 I noticed a slight change in the experiences. Not really product related, just that I was more accustomed to it. It was predictable. As corny as it may sound, I felt that I had learned much of what I could from MDMA by then. I had uncovered hidden traumas, addressed them, and was the better for it. Recently with only 2 x year, I still get a great experience from the substance. I don't feel tolerance. Is it like the first 5 times I did it? No. But the drug is doing what the drug does. I know where I am going and know what to expect. To this day, it is still my favorite substance, and I treasure those 2 x year experiences. These days, it is more of a 4 hour break from daily life than anything else. It is a mini vacation of the mind. It is just more of a well worn path then the first few times and I can predict the timeline. I know the come up, the peak, the comedown, and how I will feel at each step along the way.

I have had batches across the years that are not as good as others. And 1 or 2 that were completely bunk.

I have a very mixed opinion on this thread.

MDMA is more popular than ever. This means more demand, and more supply. When something is scaled up that much, there is going to be some loss of quality here and there. As a percentage of the total product out there in the world, there is most likely a higher percentage of dirtier or not as potent product as compared to 20 years ago. However, I am not a buyer of the so called "Meh" and "Magic" mdma theory. Yes, some product is always better than others. That will always be the case.

My humble opinion is that a good majority of the MDMA out there is solid, and that much of the problems with MDMA here on this thread have to do with a few issues...

1.) Nostalgia for the first few experiences

2.) Tolerance

3.) Some Bad Product (not the main factor)

4.) Lifestyle

Number 4 is huge, and to me is NOT addressed enough in any of these forums. How many times have you read something like ....."I have had a break from MDMA for 5 years. During those 5 years I only rarely consumed alcohol, speed, and occasional cocaine. The experience my first time back after 5 years was not good!" Our brain and body thrive with low stress, good diet, exercise, sleep, and a sense of purpose. A 5 year tolerance break from something doesn't mean much if your lifestyle is not healthy. In order to reverse MDMA tolerance, the brain essentially has to re-wire and heal itself. This takes time, but it also takes a healthy lifestyle. The lifestyle is more important than the time off in my opinion.

With all of this said, I believe that the main issue people have with MDMA not working is related to one of the above problems. Perhaps you have gained the necessary insights you needed from MDMA, and the potential isn't as great for you anymore. Perhaps your lifestyle isn't that healthy. Perhaps you have bad product. All of these scenarios can come into play.

I realize this will not be a popular opinion with many here, and will be countered with "I gave this product to 10 newbies and nothing happened". Well...if that is really true, and you actually managed to get that many MDMA naive people together to roll, then perhaps you do have bad product and need to look elsewhere. However, I have been able to get reliably good product over the years on the darkweb by doing a moderate amount of research. I'm not using any unkown or secret vendors. They are generally well known and have good reviews.

Either way,. thank you for reading, and don't forget to look after yourself and your well being. The reward may be a "magic " roll in the future, or even better yet a more sustainably positive existence on a day to day basis.
 
Thanks for posting, @JoEhJoEh & @Observer01!

Observer01, would you mind sharing your general region just so we have a better idea of your situation? Are you in the US and working with US DW vendors, or are you in Europe, the UK, or elsewhere?

What you are describing about MDMA becoming more predictable is definitely something that I experienced as I rolled more frequently, even when I had access to quality product. It was a very predictable experience, especially since there were not a lot of variables for me and it was typically just me and my partner listening to music and enjoying each other at home. However, it was that predictability to the experience that made the change in the experience so noticeable. You said, "I know where I am going and know what to expect...It is just more of a well worn path then the first few times and I can predict the timeline. I know the come up, the peak, the comedown, and how I will feel at each step along the way." That is exactly how I used to feel about MDMA. What would you think if that well worn path suddenly became unfamiliar and lacked the mile markers along the way? What if the come-up, the peak, and the comedown suddenly changed for you?

For me, there is a notable difference between a very familiar and predictable MDMA roll and the experiences I have had with this subpar product.

As for lifestyle, I cannot speak for anyone else in this thread, but I do not drink at all, do not do cocaine/meth/opiates, am at a reasonable weight, and eat healthy. I regularly check in on vitamin levels, and I do have low vitamin D which could be an issue, but I think that is pretty common. I have some hormonal imbalances that could be impacting things. The only other drugs I have used have been LSD, mushrooms, and 2CX substances.

2C substances have definitely gained that predictable quality that you reference in your post, and they do not have as intense of an effect as they did originally. However, unlike the sudden change in the MDMA experience, I find 2C substances to be very easy to recognize with characteristic qualities that make it very clear what drug was consumed. Dosage is a precise science there, and I know the variation I will experience between 15-35 mg and can tweak it according to my set/setting to achieve exactly what I want. Again, all I can say is that there is a difference between experience making something predictable and something changing so much that you feel like you took a different drug.

I feel like I know what you are describing in your post, and I have experienced it myself. For me personally, the "meh" experience is different than a "MDMA has become predictable" experience. I wish I could explain it in a way that made it clearer, and I wish I could go back to that well worn path of satisfying predictability.
 
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