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Alcohol Alcohol Megathread

I'm sure you already know this but it's the alcohol ruining your appetite. I drank very heavy for 6 years and just like you I wouldn't get hungry until night time. If I tried eating breakfast or lunch I would gag. I would only eat maybe 750-1000 calories at dinner. Your body adjusts to the calories from the booze and your gut flora is fucked up.

I quit drinking about 10 days ago and my appetite is slowly coming back.

Weed helped me eat but only so much.
 
You need to start taking probiotics as Snaful said.
The good bacteria in your digestive tract will decrease very rapidly after a "tipping point" is reached and they're no longer able to do their job, which is keeping the bad bacteria in check as well as break down the food you eat.
All that alcohol is just killing them off and probably general downregulation is occuring. Acid reflux and ulcers are also reported symptoms.

Your alcohol intake means quitting cold turkey is potentially dangerous and a tapering, as any alcohlic with tell you, is a bumpy road to say the least. Gotta start somewhere and probiotics are a step.
 
tweakerguy said:
Acid reflux and ulcers are also reported symptoms.

a tapering, as any alcohlic with tell you, is a bumpy road to say the least.
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Yep. I also had constant acid reflux and quite a few ulcers. Alcohol is such a destructive drug.

Tapering is nearly impossible. The only times I was able to quit was with benzos or phenibut.

I hate alcohol.
 
tweakerguy said:
I figured. It doesn't help that advertising is everywhere all the time and social stigma is almost non existent for a substance that's so destructive. :?
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It's not even that I don't think. I still wear a few shirts with alcohol logos on them, it doesn't trigger me at all - nor do liquor stores. All my family members/friends still drink, that doesn't trigger me either... it just pisses me off seeing drunk people now (and makes me think about how foolish I acted when I was drunk).

I think it's just the fact that alcohol is so profoundly disinhibiting. If I tried to just buy a 6 pack, for example, when I finished that the urge to keep drinking was completely overwhelming and uncontrollable. Even with benzos I could call it a night, but not with alcohol. That and the fact that you can't really buy an odd number of beers/wine/liquor. It's a 6, 12 or 24 pack... or 1,2,3 bottles of wine or a full bottle of liquor. Hard to buy a 12 pack and just drink 9 if you get what I mean.
 
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Alkohol doesnt last long for me even in large disesuaikan like 3rd of a boþtle.

I want to drink.on.my xanax days to avoid this build up of the tolerance to the xaxaxa but at how much will the cross tolerance be eg my tolerance hàs shit up to to ²0mg as i took it 7 days at 3 days then 5 days..apologize if this doesnt make sense... no.sglèep.and 20mg.x oh ýèah and ah i aint never ran from nothin but the police
 
Would diazepam cause an inaccurate reading of BAC level? For instance, I had 17 standard drinks over a 5 hour period. According to sites I searched it should be 0.00 in less than 11 hours. But does diazepam cause a false reading for DUI?
 
Not to my knowledge. Diazepam can definitely potentiate the effects of alcohol because they're both GABAergics but it doesn't alter the expression nor inhibits the enzymes responsible for ethanol metabolism (mainly alcohol dehydrogenase but also CYP2E1 and to a lesser extent Catalase).
The main factors influencing the BAC are: sex, body weight, stomach contents (food) and also genetic differences (ethnicity and stuff like that), IIRC.

Edit: I can't say for sure, there might be some complex interaction between the 2 but it most likely won't alter your BAC reading to any significant degree.
It will make you feel more drunk though, benzos and alcohol can be a dangerous combination. You could have an accident even if your BAC is low (impaired coordination, etc...)
 
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Dude, you drink too much. Yes, maybe I'm talking like a bore now, but it's true. But I'm not worried about the amount I drink, but the reason. In one of the messages you said that you drink in order to relieve anxiety. I can tell you with confidence that this is the first step to addiction. Drinking at a party and drinking to hide emotions are two different things, with different consequences. You urgently need to do something about it. If you have psychological problems, then contact a psychologist, and do not hide them with various substances. Also, I would not use passionflower, as your body is now weak. I have problems with blood pressure, so I often have trouble sleeping. Valerian drops usually help me. Yes, I understand that this is a completely different thing and the feelings from it are different, but if you need something to sleep, then this is a great option. Don't be afraid to admit that you are addicted. You should address this problem as soon as possible. It seems to me that the most effective in this case would be private alcohol rehabilitation. I hope you can escape this sad fate. Good luck !!
 
It gets me every time and it's really fucking annoying 'cause I like to drink every now and then. Like seriously, I can't breathe through my nose at all unless I take opiates/opioids with it.
 
To answer your question based on observations and personal experience, it can lower your appetite and is high in calories to boot, but it can also increase appetite in some folks (hence the "beer/booze munchies"). In my experience alcohol increases my appetite, but for unhealthy foods unlike weed, which for whatever reason drives me to make better meal decisions. My fiance on the other hand eats like an anorexic ballerina, but on the same note he'll kill off a whole case of beer in 1 night by himself. In his case it has greatly reduced his appetite to an unhealthy level for a man his height and size (he's a rather skinny guy aside from his growing beer gut). As a bartender, I 2nd everything mentioned about alcohol being a destructive substance. I don't see how its still 100% legal across the board but weed isn't in most US states. And yes, I know from experience that its harder to abstain from than most drugs. I even have more self-control with opiates/opioids than booze, which is strange because I prefer painkillers over alcohol. Something about alcohol is very impulse-driven. Its like a bag of chips. 1 is never enough despite having your fill of it. I'm glad I stopped myself before it turned into a problem like it has with so many family members in my life. Being addicted to pain meds is bad enough without being an alcoholic on top of it.
 
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falsifiedhypothesi said:
I don't know how to help you, but please don't mix opiates and alcohol.
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My painkiller doses are much higher than my alcohol consumption, but I wouldn't suggest mixing substances to anyone, as it can be very fatal. I only drink once or twice a week but I take a painkillers daily. Its a routine I've stuck with for years. Definitely not a recommendation though. Not everyone knows how to balance substance combinations properly and a lot could go wrong. I'd still like to find out why I keep getting congested when I'm drinking though. If it weren't for the scarcity of opiates in my town, I'd probably never touch alcohol aside from what I serve people at work (I'm a bartender).
 
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F.U.B.A.R. said:
I suffer with this as well, especially after drinking spirits.

I think it may be an histamine reaction as alcohol contains histamine. It also contains sulphites which can provoke allergic reactions.

Perhaps antihistamines may help? I keep meaning to try them myself but never have any to hand.
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I wonder if opiates are antihistamines as well? Its the only thing that seems to clear up my sinuses when I drink.
 
I recently started drinking a little bit, after years of sobriety and taking care of my body/life. One thing struck me, I was very aware of the toxic effects of ethanol, the "hangover" seemed to hit within 3 hours and the buzz just doesn't last very long either. A headache and general dysphoria begin, of some degree. I don't want to drink more than "one drink" for various reasons, and this negative effect definitely helps me on that level.

To cut to the chase:
I have a pretty solid collection of adaptogens and other herbs/supplements. I'm very interested in coming up with a stack that would greatly reduce the toxic effects of ethanol (experienced or underlying) . Not so I can drink much more, but so the experience is more enjoyable and it doesn't feel like I am just dumping crap in my body. (I have pondered other drugs, but let's leave that out of this thread.)

To begin, I know that inhibition of alcohol dehydrogenase could be promising, this could extend the effect and help avoid production of acetaldehyde (one of the main toxic byproducts.)
I also know that dehydration is a big aspect of the hangover effect, so proper hydration and electrolytes could definitely be beneficial.

Is there any other things we can come up with? It seems like ethanol metabolism is complex and I would love your guys' help to tackle this. I read about ethanol metabolism inducing hypoxia-inducible factor 1α (HIF1α) because it produces a hypoxic state in the liver. This produces fibrosis. If we can find a way to avoid this that would be awesome.

Using things such as silymarin or even better bupleurum (much better effects and bioavailability) seems promising. But I wonder if having boosted liver enzymes would make the buzz decrease faster?

I need to study this more, it's a deep topic. I was looking at this article some:

Ethanol Metabolism - an overview | ScienceDirect Topics

www.sciencedirect.com www.sciencedirect.com

Thanks guys, I'm exited for your responses.
 
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