N&PD Moderators: Skorpio | someguyontheinternet
Actually I'm quite tweaked and am trying to figure it out for FACAP, 4F-Phenyl-1-CycloPentyl-(2-Methyleminate) and can't select chirals on my mobile phone on STP. Would you point it out with this given example?Has anyone considered that different enantiomers of a chiral compound have different actions. AMT is a good example. When resolved, only 1 isomer has 5HT2a affinity, the other is just stimulating. I suspect that 6,a-DMT would produce entactogenic activity. 6,a,a,-TMT (achiral) is another interesting one.
Actually I'm quite tweaked and am trying to figure it out for FACAP, 4F-Phenyl-1-CycloPentyl-(2-Methyleminate) and can't select chirals on my mobile phone on STP. Would you point it out with this given example?
When methyl benzoate is volatilized and then highly diluted with a gaseous non-odor masking diluent, the aroma of cocaine is provided. Similarly, when a mixture of methyl benzoate, methyl cinnamate and the dimethyl ester of truxillic acid is volatilized and then highly diluted with a gaseous non-odor masking diluent, the aroma of various grades of "street cocaine" is provided.
A unique feature of the present invention is that the aroma of cocaine is not merely imitated, but rather, the actual aroma of cocaine is provided without the use of any cocaine or cocaine related materials. Since the actual aroma of cocaine is provided by the present invention, it is possible to use the present invention to establish a chemical model for the aroma of cocaine. This chemical model may then be used in various qualitative and quantitative analytical techniques.
Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate
Dan Wu and View ORCID ProfileDonal F. O’Shea
PNAS March 24, 2020 117 (12) 6349-6355; first published March 10, 2020
Abstract
A combined analytical, theoretical, and experimental study has shown that the vaping of vitamin E acetate has the potential to produce exceptionally toxic ketene gas, which may be a contributing factor to the upsurge in pulmonary injuries associated with using e-cigarette/vaping products. Additionally, the pyrolysis of vitamin E acetate also produces carcinogen alkenes and benzene for which the negative long-term medical effects are well recognized. As temperatures reached in vaping devices can be equivalent to a laboratory pyrolysis apparatus, the potential for unexpected chemistries to take place on individual components within a vape mixture is high. Educational programs to inform of the danger are now required, as public perception has grown that vaping is not harmful.