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Opioids Tianeptine Megathread v1

I take effexor the biggest factor that helped with my ssri induced ED was time i just stuck with it and in a few weeks it was completely gone now i have zero ed issues on effexor. But then again I wanted to die soo ed for like 2-4 weeks ill take it.
 
If tianeptine is not helping you at recommended doses then stop now. It's only gonna set you back, antidepressant effect everyone differently, you won't know what side effects you'll have until you take it yourself.
 
It doesnt matter. What i mean that is if you take any drug that is a ssri just because you get ed doesnt mean it wont go away. I had erection problems only for the first few weeks. Which might be not a big deal if in my case i wanted to die.
 
Will tiapeine make you test positive?

Drug test questions technically aren't allowed here, but if you take a quick glance at the structure of tianeptine vs that of morphine, we can probably assume the answer to be "no".

However, using it as a substitute for an opioid habit is highly discouraged, as it isn't particularly potent, and has a very short half-life.

At therapeutic doses (3x12.5 mg/day), it is arguably a really good antidepressant though.
 
Tianeptine has an extremely short duration of action, I got really really heavy into using the sodium version a few years ago. Started at ~100mg, but at the end I was using ~5-7 grams each day..........and not feeling hedonistic-ally high and wonderful all day, but just staying out of W/D. Doses only really lasted 4 hours max. The "high" was really just about 1-1.5 hours long (while I actually could get high), and after was just a feeling of normal before the tianeptine completely left (and that window of normal got smaller and smaller each day).

I was waking up every 2-3 hours through the night in W/D, and let me tell you, eating that much tianeptine fuckin sucked. It'd blast through my stomach and I'd throw up pretty often, most usually on the morning. The taste of that was so bad, the stomach acid and tianeptine mixed to make this acidic slush thatd get in my nose and everywhere and the taste would never completely go away, even with brushing my teeth 5 times in a row and gargling mouth wash. I had 2 shipments arriving each week, the max i could order without a research grant/permit thing. i had to spring for overnight shipping, and eventually, I spent so much each time I'd get free overnight shipping (that should tell you how much I was spending).

If you've been addicted to hydromorphone or any other opioid, the last thing you want to do is replace that with a MUCH shorter acting opioid that operates like tianeptine. I'd pretty much guarentee your doses would fly out of control, and since youre actually prescribed them, it'd be pretty bad to be OUT of your monthly script after 3 days.

It'll take care of that opioid absence problem. but not for long, and it is the least sustainable opioid to use for anything except what its prescribed for in the suggested doses and NO more
 
I have prescribed tianeptine in 12'5mg tablets, two daily. I took large amounts as 250mg and get a strong narcotic high which ever ends in a deep dream. Now I have not tianeptine but when I get the next package I will take it adequately taking only one pill in the morning and other in the evening
 
I think there is no reason for me to take tianeptine for depression,because i was taking a lot of hydromorphone, much stronger opiate agonist, so tianeptine in recommended doses is not effective for me probably due to my opiate tolerance...i may give citalopram a try but i would rather been prescribed more stimulating antidepressant because after i stopped using opiates i dont have any energy and i cant feel pleasure out of anything... but my doc is asshole.
 
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The inability to get pleasure out of what you do and the low energy are latent effects of your opioid use. The biggest hurdle I had to pass was that once acute W/D is over, the "getting clean/stopping opioid use" journey is just beginning. All of that is due to conditioning and reinforcing effects of chronic opioid use. Basically, everything is better with opioids, so you do that for awhile and enjoy it completely. The reality that everything really DOES seem better reinforces that belief and compels you to do it again, and again, and again, until its ingrained into your daily routine. It doesn't take very long to get there either.

The only way to *really* get past this hurdle of feeling like ass and not feeling anything is to make yourself get up and move and start replacing habits centered around opioids with other habits, and working to find what gives your life meaning. Medications will help, but by themselves they are going to be a disappointment. Personally, it took therapy, help from friends and family, and finding a good doctor to really help set me on the way.........and im still falling back into it and rerlapsing. its hard, and it sucks big time.

Get rid of your asshole doctor and find one who can understand where youre coming from. not easy, but it'll help you big time
 
I decided to try citalopram,i am on third day of 10mg in the morning and first day i had horrible headache, mild twitches, sweats and huge pupils...now i feel like it actually do something in terms of energy and better mood, it feels like strange dxm and speed mix...but i guess i just have to get used to it.
 
Two or three hours later of take 250mg tramadol I have had 250mg sodium tianeptine which are 20 pills of 12'5mg each one. What effect can I expect due to the past tramadol 250mg and the sodium tianeptine 250mg of right now?
 
Well all I personally feel is tired and nauseous. I'm really wish I could get that euphoric energetic feeling I keep hearing about. I tried 30, 50 and 100mg. Maybe 250mg is what it would take but I'm kind of nervous to go that high. Let me know how it goes for you.
 
At first I thought there might be a possibility of serotonin syndrome from mixing Tramadol and Tianeptine but so far by googling around I don't think it's a concern.

Check out what sekio had to say about this over in Advance Drug Discussion (nowadays called Neuroscience and Pharmacology Discussion):

Tianeptine is not a serotonin releaser or MAOI, so there's no reason the two should interact. Even if tianeptine was primarily a SRE (Serotonin Reuptake Enhancer)... it would decrease postsynaptic serotonin concentrations, the opposite of what a SSRI does.

There's a case report of someone who dropped dead in the street with ~10x the normal therapeutic dose of tramadol and tianeptine in her blood. I'm not sure if it's really relevant but it goes to show that the combination is not as threatening as a MAOI+SSRI would be.


http://www.bluelight.org/vb/threads...y-tianeptine-wouldn-t-play-well-with-tramadol

So serotonin syndrome doesn't sound like a concern but I still think you should be careful mixing the two. Their opioid effects will likely synergize. I'm not sure how the other non opioid related effects of either drug will interact though.

Maybe don't start with such a high dose of each if you are going to mix them. It might be better to start lower, say like 50mg Tramadol with 50mg Tianeptine... See how it effects you and then decide how to proceed.

In the case report sekio mentioned the girl died because she took a fatal dose of Tramadol based on the levels found in the drug screening. The tianeptine probably didn't help but her death was from too much tramadol. I would still proceed with caution...
 
on one hand in hand no over dose side effects at the or much higher levels. It does not slow down breathing [afaik ] like any other opiate. The danger is this is the worst chemical i have ever ,we the mistake of trying . The withdrawal is much worse dope. Methadone does not help, except for maybe first 4 hour s. Swets,da iherra, the whole normal withdrawal but is causes so much more.
Months of dysporia , apathy lethargy,inability to focus or get out of bed for up to 2 months after.I quit after a 5 gram day habit. I cut down ,y `0 mgs each dose till down to 1 grams then lucky , fentanyl analogues were legal so used that (fuf/maf] every half hour for 4 months. I am hooked again, brings no good feeling except the end off the [in its absence causes.
This should not be spread round for anyone to find this stuff, if people hear' chemical feels like Opiates' and they you know they going to try it.I
I ask anyone that used it for everyday for years nd stopped to tell people it is harmless.
I tried it to get off kratom, and ended relapsing in to Opiates of all kinds to try to get this ape [not ,money, off my back.
 
It helps withdrawal from Opiates because it has no cross tolerance. I used it to come off fentnyl. The problem it is addictive because it seems harmless.
It is the worst substance pitchers if abused.
 
It sounds terrible, but like something I wouldn't turn down a smallish line of if it was in front of me. So basically like a slightly safer less expensive fentadope where you know the purity, but the side effects are brutal and long lasting. Much like fentadope, tbh. Ppl talk about fentanyl having a low half life and thus being easier to recover from than longer lasting opioids but it's all relative because redosing every 30min to an hour for months on end will take longer to fix your life than the half life of fentanyl.
 
yeah the w/d is something else. I was doing ~5g-8g of it every day with 3g phenibut. The w/d was so bad I ended up going to the BSU and totally forgot about the phenibut i was taking. I was so wrapped up in the tianeptine w/d i forgot the phenibut until the gabaergic w/d started 3 days in and I started hallucinating and fell into full blown psychosis (from the phenibut w/d, not the tianeptine).

The day before I went into the BSU, I took about 500-600 pills of loperamide trying to get relief and it didnt do anything. I Also drank a bottle of cough syrup with only dxm as the ingredient and that just made me confused and miserable. Kratom didnt help either. It was bad.

It took very little time to go from doing 100-200mg daily to doing 10g daily, took about 3 months and it was non stop bull shit. Dosing every 3 hours for 3 months really sucked.
 
Jeez, 10g daily of anything, that's active at 50-100mg, daily, that almost sounds like torture, being under this drugs effects for that long and that heavily, and then having to endure the withdrawal while a bunch of other stuff is going down. I hope you're doing better now. I'm glad I never tried these opiate RC's, the craziest thing I got in the mail was some tryptamines and 2c's and etizolam/kratom. O-desmethyltramadol was available at one point and I'm glad I didn't try even that, seeing as how my opiate addiction was mostly iv buprenorphine. This stuff (tianeptine) is actually available for extremely cheap, both as freebase and sodium salt, on a site that otherwise sells rc nootropics. Very enticing but I don't think I will be trying it out.
 
Yeah, I always thought that the opioid RC's would be a way to get a huge supply of opioids in a relativley easy way. I thought that getting a dick-ton of a RC opioid would give me a lot of wiggle room to taper off my other opioids, because I'd have a "practically" unlimited supply so my taper could be low n' slow and comfortable and I wouldn't have to worry about running out of drugs randomly. Also relatively cheap and semi-quasi-legal sorta.

But EVERYTHING I've seen about these opioid RC's are really bad overdoses, and (almost) worse is what happens to the ones who don't overdose. You have an endless supply of a strong opioid, and end up being physically dependent on a dose that no one taking street drugs or pharmaceuticals could ever hope to achieve on even the largest of incomes. Taking a fent analogue and ending up being in W/D if you do any less than the equivalent of like $400 worth of street heroin per day or more. So bad that if you were to seek medical help the doctors would never be able to give you the ammount of methadone or suboxone you would need to even feel slightly less miserable than death.

When I went to the hospital for tianeptine and i was on the ~10g/day dose, the BSU sucked big time. The doctors didn't know what it was and had no idea how to treat the w/d. They really didnt want to use any coontrolled substances while treating me. Since it came up on wikipedia as a "novel anti-depressant" (yes, the nurses wikipedia'd it to find out what to do, great hospital), they started me on anti-psychotics. Risperdal first, then after that wasn't "working" they tried seroquel, got REALLY bad muscle side effects from it so I got a 7mg dose of ativan and changed to haloperidol. 20mg twice a day and 10mg valium 3x a day. The antipsychotics made me exhausted, walking to the medicine window 30 feet from my room winded me and I'd have to sit on the floor instead of standing at the window. when I got out I googled haloperidol, and found out that schitzophrenics get treated with 5mg 3x a day, and I was perscribed 20mg 2x a day for...............................what? My diagnosis was unclear and it was officially "drug withdrawal".

Taking weird online drugs is a bad bet. Tianeptine isn't even known, its a bonafide prescription drug in europe with patents and research. Other RC's would make you a big question mark floating around a hospital, and you're going to be very uncomfortable most of the time.
 
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