https://image.ibb.co/fXkdBm/pyeyzolam.png
8-ethynyl-1-methyl-6-(pyridn-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4 benzodiazepine
Another variant of the pydinodiazepine scaffold.
3mg = 1 unit (10mL) of 100$ ethanol.
It proved that the positive effects of alcohol (relaxation, euphoria,hypnotic) from the negative effects (ataxia, aggression, nausea, diuretic, amnesia). From a cohort of 103, the dose/response wasn't altered by body-weight and the drug wasn't metabolized; excreted unchanged. QI-II-66 lasts too long. The T1/2 of this was 280 minutes ? 22 minutes.
After initial trials, a small cohort (N=7) proved that dependent alcohol users found that it totally prevented abstinence syndrome. We were looking into the addition of 1-amino-cyclopropanol, (AOD inhibitor) to prevent concomitant use of alcohol.
So, it all works well but to treat alcoholics, too much work for a license. As an ethanol replacement, going against a $7 billion industry meant impossible to license. That >250,000 people die from the results of ethanol clearly doesn't make it a product that no government has worked out. David Nutt & Dr. Dave have the lab-notes
The synthesis is somewhat problematic but a dare say a chemical engineer would find a route in which the -Br --->-C☰CH would make it cheap. I mean under 40p per dose unit. So even with tax and duty, if solutions were put into soft drinks, the price would match that of alcohol. That is the most important thing. Powder, while having a massive TI, can result in a 'missing weekend' (hypnotic), it is also a date-rape drug so only licensed formats would make it practical and safe for people.
Never design a drug you aren't willing to take yourself as the fist in-man. I caned an awful lot of it but I wouldn't recommend it. I have come close to paying the price, but someone has tol
8-ethynyl-1-methyl-6-(pyridn-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4 benzodiazepine
Another variant of the pydinodiazepine scaffold.
3mg = 1 unit (10mL) of 100$ ethanol.
It proved that the positive effects of alcohol (relaxation, euphoria,hypnotic) from the negative effects (ataxia, aggression, nausea, diuretic, amnesia). From a cohort of 103, the dose/response wasn't altered by body-weight and the drug wasn't metabolized; excreted unchanged. QI-II-66 lasts too long. The T1/2 of this was 280 minutes ? 22 minutes.
After initial trials, a small cohort (N=7) proved that dependent alcohol users found that it totally prevented abstinence syndrome. We were looking into the addition of 1-amino-cyclopropanol, (AOD inhibitor) to prevent concomitant use of alcohol.
So, it all works well but to treat alcoholics, too much work for a license. As an ethanol replacement, going against a $7 billion industry meant impossible to license. That >250,000 people die from the results of ethanol clearly doesn't make it a product that no government has worked out. David Nutt & Dr. Dave have the lab-notes
The synthesis is somewhat problematic but a dare say a chemical engineer would find a route in which the -Br --->-C☰CH would make it cheap. I mean under 40p per dose unit. So even with tax and duty, if solutions were put into soft drinks, the price would match that of alcohol. That is the most important thing. Powder, while having a massive TI, can result in a 'missing weekend' (hypnotic), it is also a date-rape drug so only licensed formats would make it practical and safe for people.
Never design a drug you aren't willing to take yourself as the fist in-man. I caned an awful lot of it but I wouldn't recommend it. I have come close to paying the price, but someone has tol
Last edited: