Because out of whack Testosterone/cortisol/pregnenolone or thyroid levels can cause all kinds of mental issues and the mental issues themselves also perpetuate the hormonal disturbances.
Whatever you do do not commit suicide. You have not tried even a single treatment. There are so many treatments:
Medicine can include psych meds or hormones. There are also various supplements to balance things naturally
I have experienced transient relief with hormonal manipulation. In fact, I managed to relieve myself of anhedonia completely way at the beginning of LTC. I too never had DP/DR (except recently since after ketamine infusion which didnt work but that is subsiding)
I know cotcha does not believe in the HPA dysfunction theory but its one thing that should be tested for. Unfortunately, this gets into the "gray area" of medicine. It is a thing but vastly oversimplified in most places if you look it up.
TLDR: MDMA affects the pituitary/hypothalamus and the inputs to these regions.
What do the pituitary and hypothalamus control? They control things like LH and ACTH and TSH which are responsible for testosterone, cortisol, pregnenolone, and thyroid. Now these hormones downstream themselves feedback into the brain and affect neurotransmitters just as neurotransmitters affect these hormones upstream. Theres also a ton of other stuff going on.
Keep in mind I am not a doctor but I urge you to see one and get some hope. However, please be aware that doctors may still say "evrrything is normal" even if its not technically true. This is why you need to see a very good psychiatrist that knows these things.
YOU WILL NOT BE THIS WAY FOREVER.
When I found out what I was suffering from it sort of calmed me down.
My emotional numbing was the first thing to go away btw.