Wellbutrin (Bupropion) - First Time - Nasal use

[ZboijieA]

So I have looked around and found very different reports of snorting wellbutrin. This is mine.
I peel the coat off of a 300mg tablet and grind it to a fine powder. I make 8 equally sized lines. I intranasally take 2 lines at a time with 15 minutes between each set. The first 2 cause an instant rush: like drinking 10 cups of coffee but without the jitters.
I put some music on and feel pretty good, then every 15 minutes i do another 2 lines (whole process over an hour). Each time i do another 2 lines i feel more high (smoking a cigarette between lines feels really good). After snorting the last two lines i feel the effect for between 1 and 1 and a 1/2 hours: slowly bringing me down with no negative side effects.
The effect is similar to doing some really stepped on cocaine or a bad batch of cathinone: colors become more vibrant and things become more interesting, not unlike dexetrine: my hearing at first is blocked as though taking off in a plane but quickly my hearing seems to be more clear than before. Pleasurable, but if you have other ways to get high i suggest using those: it definately is not a "drug of choice". It leaves a bad/numbing drip down the back of my throat that after the first few uses becomes of little annoyance. The first few times snorting the pill is incredibly painful and can cause a small nosebleed.
Wellbutrin lowers the threshold of seizures so i advise not using more than 600mg per day and if possible (but not necessary) taking a small amount of an anticonvulsant afterward in order to prevent seizure. Do not mix this drug with others that lower seizure threshold such as alcohol.
In conclusion:
Wellbutrin will cause a high and does have recreational value if used correctly. As with abusing any drug it is dangerous.

Tagged by Xorkoth
substancecode_wellbutrin
substancecode_bupropion
substancecode_antidepressants
substancecode_pharms
explevel_firsttime
exptype_positive
roacode_nasal

 

[ShardHunter]

How did you come across the idea of insufflating Wellbutrin? Do you know others who have? Did you read about it or see it in film? Was it something you came up with on your own? Also, this is a well thought out schedule. Was this by trial and error or advice?And out of curiosity, what sort of music do you listen to while enjoying this high? Thanks! This is a new twist for me.

 

[Xorkoth]

I've heard really bad things about snorting wellbutrin, because of nasal damage.

Also worth noting that mixing this with tramadol could be fatal... as both significantly lower the seizure threshold.

 

[theGirlWithBlueHair]

How did you come across the idea of insufflating Wellbutrin? Do you know others who have? Did you read about it or see it in film? Was it something you came up with on your own? Also, this is a well thought out schedule. Was this by trial and error or advice?And out of curiosity, what sort of music do you listen to while enjoying this high? Thanks! This is a new twist for me.

bupropion is a norepinephrine-dopamine reuptake inhibitor, similar to methylphenidate (Ritalin) and cocaine, as well as the various substituted cathinones circulating around - the class to which it belongs. It has recreational potential. Don't think that just because it is an antidepressant that it isn't abusable.

It's abuse liability is limited due to its nicotinic actetylcholine activity and lowering of the seizure threshold.

If you guys read the official prescribing information, you would know this...

Abuse

Humans: Controlled clinical trials conducted in normal volunteers, in subjects with a history of multiple drug abuse, and in depressed subjects showed some increase in motor activity and agitation/excitement, often typical of central stimulant activity.


In a population of individuals experienced with drugs of abuse, a single oral dose of 400 mg of Bupropion produced mild amphetamine-like activity as compared with placebo on the Morphine-Benzedrine Subscale of the Addiction Research Center Inventories (ARCI) and a score greater than placebo but less than 15 mg of the Schedule II stimulant dextroamphetamine on the Liking Scale of the ARCI. These scales measure general feelings of euphoria and drug liking which are often associated with abuse potential.


Findings in clinical trials, however, are not known to reliably predict the abuse potential of drugs. Nonetheless, evidence from single-dose trials does suggest that the recommended daily dosage of Bupropion when administered orally in divided doses is not likely to be significantly reinforcing to amphetamine or CNS stimulant abusers. However, higher doses (that could not be tested because of the risk of seizure) might be modestly attractive to those who abuse CNS stimulant drugs.


Bupropion hydrochloride extended-release tablets (SR) are intended for oral use only. The inhalation of crushed tablets or injection of dissolved Bupropion has been reported. Seizures and/or cases of death have been reported when Bupropion has been administered intranasally or by parenteral injection.


Animals: Studies in rodents and primates demonstrated that Bupropion exhibits some pharmacologic actions common to psychostimulants. In rodents, it has been shown to increase locomotor activity, elicit a mild stereotyped behavior response, and increase rates of responding in several schedule-controlled behavior paradigms. In primate models assessing the positive reinforcing effects of psychoactive drugs, Bupropion was self-administered intravenously. In rats, Bupropion produced amphetamine-like and cocaine-like discriminative stimulus effects in drug discrimination paradigms used to characterize the subjective effects of psychoactive drugs.