Hello BL, long time lurker. I've had a troubling experience with vasoconstriction from 200ug of 1P-LSD. I already spammed about it on reddit but I thought some of you might find it interesting. It seems I've been experiencing something not unlike the prolonged vasospasm someone would with minor ergotism from some ergot based medications.
Firstly I've tripped on AL-LAD, morning glory, HBWR, each a couple of times, as well as a wide range other drugs and psychedelics and never experienced anything similar to this. I'm in my 20s, moderately physically active and had a routine physical and blood testing done a few months ago where all was normal. I use an eCig (though have now greatly reduced). I had done 4mg of etizolam the night before, but otherwise had been pretty sober leading up to the trip. I smoked weed as I was peaking.
As some others have reported, during the trip I noticed vasoconstrictive effects, bulging blue veins, some purpling in the hands, and numbness in the right forearm and hand. My palm and forearm felt a little swollen this was probably a combination of sensory distortion and numbness. This was very concerning, I considered seeking medical service (first time ever during my dozens of trips) but decided to take 1mg of etizolam instead. Things seemed to subside, the mind blowing trip continued and slowly dissipated before I went to sleep.
During the next few days things were fairly normal other than some episodes of red mottling on the palms and fingers on both hands, with veins on the wrist and top of hands being more visible than normal. I continued low dose etizolam, took codeine a couple times, and smoked weed.
After about a week symptoms seemed to peak, and my hands looked worse than when I was tripping. As seen in the picture, my hands would often switch between red mottling and purpling of the palms and fingers, with maybe some blanching in the middle parts of the fingers. My hands felt week and circulation poor. I also noticed the tips of my toes purple and I'd sometimes feel like I've just came inside from walking the snow in the tip of my feet.
http://i.imgur.com/86oFqdj.jpg - Not the best picture/lighting, and not a picture of the symptoms at their worst, but it gets the point across.
It has now been 2 weeks and things seem to be slowly subsiding, though they are still there. Without significant improvement very soon I'll be seeing a cardiologist I think, though I'm not sure what they could do other than prescribe a vasodilator.
I'm very interested in hearing if anyone else has experienced similar effects. Closest I've found regarding persisting symptoms was
this thread with regular street acid.