I Like to Draw Pictures of Random Molecules

[Nagelfar]

I took the nitrogen and the carbmethoxy and placed both of them "half-way" between where they are on the cocaine-analogs/phenyltropanes and methylphenidate and it's derivative compounds: so each have their proper ratio apart from one another for proper functioning at the transporter binding ligand site; however, with either in the exact area between where they'd be in either cocaine or MPH, respectively.

....and it ends up looking like an NMDA-receptor antagonist a la ketamine or methoxetamine, though it should be a stimulant. Thoughts? (on NMDAr activity, for instance, versus stimulation? Maybe it's a shorter stimulant like "pemoline", for instance)?

 

[SteamboatBillJr]

Also, DOB-DragonFLY is only there once.

You're correct on this point. I looked again, I was wrong.

 

[roi]

3-methyl-2C-B, similar to 2C-G. Probably no really easy/cheap synthesis for this one.

 

[Incunabula]

Thats so funny Roi I was just thinking about this one last night. It's kind of a ring-opened 2CB-fly, but with obvious parallels to 2CG too. It's probably difficult to synthesize, and I guess there's no reason it should be more potent or interesting than 2cb-fly.

I guess the same could be done with Ganesha, and theoretically still retain some activity. Not that Ganesha doesn't sound difficult enough to make already. Sorry for making the images too big, but I'm on my tablet, and resizing doesnt work for some reason.

 

[neurotic]

^ why not close these 3 and 4 methyls into a MD ring, forget about the one in the fifth position and make a dimethoxy analogue of MDA... i'm sure someone has come up with that idea before though (hell im sure people already came up with MD rings on every molecule already)... you could call it DO-MD or something

 

[Incunabula]

You mean forget about the 6-position methyl, right? The 5-position is the methoxy, which is indispensable for it to be a psychedelic.

Shulgin made the compound you suggest. It's called DMMDA.
https://www.erowid.org/library/books_online/pihkal/pihkal082.shtml

 

[neurotic]

You mean forget about the 6-position methyl, right? The 5-position is the methoxy, which is indispensable for it to be a psychedelic.

Shulgin made the compound you suggest. It's called DMMDA.
https://www.erowid.org/library/books_online/pihkal/pihkal082.shtml

oh yeah, sure, my mistake... and interesting, i'd think it'd be inactive but shulgin actually reported it feeling like 75-100ug LSD... not bad at all

thought of a few phenidate analogs, first starting with N-methyl MPH and EPH

then amphetamine, methamphetamine and phenethylamine analogues of MPH... could make EPH ones too

i made one with a pyrdine in the place of the piperidine ring also but this image uploading thing is tiring lol

EDIT: just thought of the 'amphenidate' name for the amp analogue of MPH lol i personally like the way it sounds

 

[adder]

As nice as it sounds, it doesn't make sense. The "phenidate" part of the name in methylphenidate is basically a short name for phenyl(piperidin-2-yl)acetate.

 

[Nagelfar]

EDIT: just thought of the 'amphenidate' name for the amp analogue of MPH lol i personally like the way it sounds

Reminds me of a Chinese film about homosexual amphetamine addicts named "Amphetamine", which is a play on words, because in Chinese "Am-phet-a-meen" (forget whether Mandarin or Cantonese; if it were a film out of Beijing or Hong Kong) sounds like "Is this my fate?"

 

[roi]

Whoo cannabinoid hybrids. Probably still CB-2 heavy.

 

[Nagelfar]

Whoo cannabinoid hybrids. Probably still CB-2 heavy.

The convoluted ones are always beautiful to my eyes. Looks like a variant of Diclofensine a little bit.

 

[Nexus_Tripper]

^ why not close these 3 and 4 methyls into a MD ring, forget about the one in the fifth position and make a dimethoxy analogue of MDA... i'm sure someone has come up with that idea before though (hell im sure people already came up with MD rings on every molecule already)... you could call it DO-MD or something

Because that already exists and is already called DMMDA.

 

[neurotic]

As nice as it sounds, it doesn't make sense. The "phenidate" part of the name in methylphenidate is basically a short name for phenyl(piperidin-2-yl)acetate.

i couldnt come up with anything nice from aminophenylbutanate - 'amphebutate' sounds lame tbh - so i settled for that

also just noticed that the MPH PEA analog's corresponding carboxylic acid is a phenylalanine isomer

Reminds me of a Chinese film about homosexual amphetamine addicts named "Amphetamine", which is a play on words, because in Chinese "Am-phet-a-meen" (forget whether Mandarin or Cantonese; if it were a film out of Beijing or Hong Kong) sounds like "Is this my fate?"

now i wanna watch that movie lol

 

[adder]

I guess we'd have to name them "methylamphenidate", "ethylamphenidate", "methylmethamphenidate", and so on to differentiate between different esters. And these names aren't bad to be honest.

 

[neurotic]

indeed they sound nice

the 'standard' methyl ester could be simply amphenidate tho - i am obsessed with this name now lol

idk what activity to expect from them tho, not even how one could improve MPH - as much as others hate it i love it
any thoughts my fellow MPH/coke lover Nagelfar?

 

[Nagelfar]

idk what activity to expect from them tho, not even how one could improve MPH - as much as others hate it i love it
any thoughts my fellow MPH/coke lover Nagelfar?

I gave some of my 'structural' thoughts on the last previous few pages. Nothing new has come to mind yet. I'd like to get binding info, rat drug discrimination "likeability" tests with the "restricted rotational" analog of MPH, personally, and see if it has better affinity when 'static' or when fluidly rotational in its branches.

I made a HDMP-28 version of the restricted rotational analog too:

It just gives me the "look-feel" of a 'good' stimulant. (of course, such is meaningless pseudo-intuitive science)

 

[Dresden]

I don't know, but 2-aminotetralin, which granted is only somewhat similar to that structurally, will give you seizures starting with 100mg. I had high hopes for 2-benzylpiperidine, too, but it got uniformly bad reviews.

 

[overeasy]

do u know anything about tramadol? i used to take it 9 months ago i just got a script today and have taken 700ml so far today, i remove the time release and there is a perfect little small pill inside, anyways would like to know more about it.

 

[Nagelfar]

do u know anything about tramadol? i used to take it 9 months ago i just got a script today and have taken 700ml so far today, i remove the time release and there is a perfect little small pill inside, anyways would like to know more about it.

Check out O-Desmethyltramadol, which is actually an efficacious opioid. Fatal overdoses linked to it (not because it is on par with the likes of Fentanyl or any such, but rather because it laced some Kratom strains sold by certain vendors and it is more potent than morphine.)

 

[roi]

Speaking of O-DMT..