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[MEGA] Synthetic Cannabinoid Discussion - Take 4

Toz said:
Anyone tried MMB-Chminaca yet? I just looked at the molecule and it seems like it could be a more potent version of AB-Chminaca but I have yet to read reports.
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more potent than chimmychonga? no fing way!

CHIM is 10X more potent than JWH-018, but has a weird threshold unlike 018, no matter how high the dose no fast heart beat / parnoia set in,

in fact you don't get any higher from 5mg than you would from 50 imho...it's a platue, IMHO

the only thing you get from higher doses is more tolerance and higher physical addition I mean like horse type withdrawal fo real...

better taper down or you will get sick as a dog.

CHIM does not need to be more potent it needs a different metabolite to be more effective IMHO,

perhaps this structure will render one more like 018, that would be great.

be safe guys, as I have been saying since synth mega 2, this shit ain't no joke! and needs to be respected!
 
maddawg300 said:
If weed was cocaine then synthetic cannabinoids would be crack.
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there are many crackbises of synth noids AM2201,5fUR144, for examples, but there are also many mellow ones, pinaca, thj122, am1220, am1248

just like weed has homegrown, mids, on the mild side, longer duration if they are CBD strains and haze, Kush, AK with like 18% THC and up.

what makes these stronger ones crackabises is the extreme high, the peaking of the CB1 receptors that drops off within like 20 mins.

while the other strains of weed that have equal parts CBD reduces peaks, 7:7 ratio is ideal, by slowing the uptake and spanning it out over a longer period of time....along with slowing the break down of anandamide (an endocanbinoid produced in the brain) which give us a general sense of well being, this is also produced when we eat chocolate...

but I digress....%)
 
Mixed 1g to 56g ?? incredibly potent ? You are smoking only the herbal blend without mixing with 1 cigarette per jojo ?
 
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What is the safest Syntheric cannib, is everyone's oppoinin ? Which also has the closest effects to weed!
 
Sorry for the self-promotion, but I've been making some posts over in the neuroscience and pharmacology discussions forum that might be relevant/useful over here. I've been thinking about the mechanisms that may underlie the kidney damage and other side-effects of the synthetic cannabinoids and have (what I think) are some plausible ideas and some harm-reduction suggestions. There's a lot of detail in the post itself which is probably as clear as mud if you're not as much of a pharmacology geek as me, but I've basically come to the conclusion that synthetic cannabinoids in general probably have the same kidney risks as NSAIDs (long term use of NSAIDs like aspirin and ibruprofen raises the risk of kidney cancer by about a quarter). Some may potentially interact with their own metabolites (or some prescription drugs) to cause acute kidney injury (this is what I think happens with XLR-11. one metabolite functions as an inhibitor of the enzyme responsible for breaking down another metabolite that ends up causing oxidative damage to the kidneys).

I just finished writing a post about some other troublesome aspects (5-ht3 antagonism). The reasoning behind the conclusion below can be found in the original post, but the conclusion itself should be pretty clear, hopefully, so I'll include it here (mods, please let me know if the copy/paste thing isn't OK. Thanks):

In conclusion, it is plausible that synthetic cannabinoids and commonly prescribed 5-HT3 antagonists share some of their effect profiles with an overlap in potential dangers and interactions. In addition to the possibilities of NSAID-like interactions mentioned previously, long-term and heavy use of synthetic cannabinoids may cause significant 5-HT3 antagonism resulting in a withdrawal syndrome involving rebound symptoms including vomiting and diarrhoea. There is a known risk of long QT syndrome associated with 5-HT3 antagonists, which can lead to tachycardia and sudden death, and this may also be a risk with synthetic cannabinoids which may be mitigated (though not eliminated) by avoiding combinations with other drugs (prescribed or otherwise) that also have this effect, and avoiding use when electrolyte imbalances are likely. Another danger is serotonin syndrome and similar avoidance tactics are likely to be prudent. There are also likely to be further complications due to the broader effects profile of the synthetic cannabinoids, and at least one 5-HT3 antagonist has been associated with severe, occasionally fatal gastrointestinal disease. Users of synthetic cannabinoids should not assume that the effects or safety profile of the drug can be purely attributed to the difference between partial and full cannabinoid receptor agonism. [ http://www.bluelight.org/vb/threads...nabinoid-kidney-damage-speculation?p=12776861 ]
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Oh ROXIanne! said:
Can anyone recommend a good ratio of ab chminaca for a blend? My friend is having a hard time on probation and there is no way she is responsible enough to vape the pure chem. I had a good system for the JWH's but when I tried to use am2201 I underdosed for the sake of caution and did not end up with an enjoyable end product.
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i like 5 grams per QP, that's for that one hit wonder though.
 
Someone can recommend a good ratio of mmb-chminaca too ? I'm not a herbal lover so i like to put less(0,10g) and combine with 1 cigarette.
P.S , I got a tolerance with the ab-chminaca ( 5:40 ratio , if this helps )
I think this is not a good idea to ask here but ... PM
 
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thenightwatch said:
AB-CHMINACA, AB-PINACA, and THJ-2201 are being federally banned in the US

http://www.deadiversion.usdoj.gov/fed_regs/rules/2014/fr1219.htm

effective January 20th, 2015
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http://www.bluelight.org/vb/threads...uling-of-several-(abCHMINICA-abPINICA-TH2201)

made a thread here too. Mods please merge it here with thenightwatch's if necessary. I just thought it should be more visible in case vendors continue to stock these after 1/20.

Shits on a fire sale now.

For my entire lifetime $ debit for cannabis the plant I could by enough of this to get the whole earth stoned a few times over.

Kickstarter?*

lol



*-to be construed as a joke and not an attempt to get the entire planet or any segment of it high, though a lot would probably benefit from being a lil stoned.
 
First time poster. Formerly I was a producer of a local blend in the post JWH-018 ban using a separate JWH---- and I'm waiting to see how things go with a certain case in my area concerning "Scooby snacks" to possibly play again. I got out when I had a fire.....50lbs leaves and 5gal acetone lil bonfire lol Full police escort, Vice squad in hospital, 60 lbs seized...No charges. Here is the advice...Always say it isn't to consume, you are not making it to consume, it makes your incense burn longer, gives a cool color to the smoke, etc When trying something new always make it way weaker than you think it needs. Take a whiff and wait a bit before just going full on. You can always add more but you can't take it away after it aroma has saturated your senses. A question---Is Mmb-Chonga covered under the recent ban in the US?
 
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Ya I don't think going on public record admitting to blend production is such a good idea,

friendship request denied, sorry. I surround myself with people a little more research savy these days, no offense intended, just how it is now.
 
niflheim said:
Sorry for the self-promotion, but I've been making some posts over in the neuroscience and pharmacology discussions forum that might be relevant/useful over here. I've been thinking about the mechanisms that may underlie the kidney damage and other side-effects of the synthetic cannabinoids and have (what I think) are some plausible ideas and some harm-reduction suggestions. There's a lot of detail in the post itself which is probably as clear as mud if you're not as much of a pharmacology geek as me, but I've basically come to the conclusion that synthetic cannabinoids in general probably have the same kidney risks as NSAIDs (long term use of NSAIDs like aspirin and ibruprofen raises the risk of kidney cancer by about a quarter). Some may potentially interact with their own metabolites (or some prescription drugs) to cause acute kidney injury (this is what I think happens with XLR-11. one metabolite functions as an inhibitor of the enzyme responsible for breaking down another metabolite that ends up causing oxidative damage to the kidneys).

I just finished writing a post about some other troublesome aspects (5-ht3 antagonism). The reasoning behind the conclusion below can be found in the original post, but the conclusion itself should be pretty clear, hopefully, so I'll include it here (mods, please let me know if the copy/paste thing isn't OK. Thanks):
Click to expand...

I don't know if this helps the direction of the discussion or not but Rimonabant and/or Cannabidiol (CBD) can be helpful to slow down or possible reverse adverse effects.

Hospitals wont give it to you tho, at least ones around here, synth can overdose is an insurance liability in this state they have to sedate you with benzos and send you to rehab facility that has those types of charters.

they will tell you something like "we don't have any beds" in hospital with 5 empty floors! they dont even care what noid it was! as far as they are concerned you were dumb enough to do it you deserve to die! not cool. but ya, they just wait to see if you survive and leave the rest up to the autopsy report for the bans...
 
maddawg300 said:
If weed was cocaine then synthetic cannabinoids would be crack.
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In older times I would say good hash and oil to be that, metaphorically.

I'd rather have 90% THC oil than any 'noid, even if I liked AB-FUBINICA, the amount I got for free was ridiculous, I just ended up giving it to friends, I barely needed to pack the bottom of a bowl of the spiked damiana to get a high that wouldn't freak me out, I never freaked out with potent oil, but I was wassssted. Especially the ridiculous joints made with papers that had oil spread on it. A deluxe we would call.
 
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