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GDF11 - Could The Blood of the Young Make Us More Youthful?

lolwhatzdrugs

lolwhatzdrugs

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http://www.fromquarkstoquasars.com/could-the-blood-of-the-young-make-us-more-youthful/

GDF11 -http://en.wikipedia.org/wiki/GDF11

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Could The Blood of the Young Make Us More Youthful?
May 6, 2014

In 2012, researchers at Stanford University discovered that they could rejuvenate the bodies of old mice by injecting them with the blood of the young; however, they weren’t quite sure how the process worked. Now, researchers at Harvard and Stanford independently determined that a protein, GDF11, is able to rejuvenate a number of different systems in the bodies of the aged. Young blood can reverse cognitive decline, improve muscle function, and improve the exercise abilities of those who are (to put it mildly) past their prime.

This discovery stems from a (somewhat abhorrent) study from the 1950s in which researchers from Cornell University delivered the blood of young rats into old ones by joining the rats via stitching the skin on their flanks together. The team ultimately discovered that the cartilage of the old rats looked more youthful than it did in rats who did not undergo treatment. As previously noted, the researches didn’t know why this worked.

So in 2000, the study was tried again. This time, researchers were looking specifically at stem cells. These cells play a vital role in keeping the young, well, young. When tissues are damaged, stem cells produce new cells to replace the dying ones. However, in the elderly, the stem cells begin to falter and do not produce new cells. To be clear, the stem cells do not die. They are still there; they just aren’t working right.

The scientists wondered what would happen if the stem cells were bathed in a river of young blood. Okay, so that last bit was a little heavy on the figurative language. Essentially, they wanted to know how the stem cells would react when it encountered young blood, and if there was anything in the young blood that helped the stem cells regenerate. And as it turned out, the rejuvenation does take place because of the stem cells. Ultimately, they determined that there was a compound in the young blood that could awaken old stem cells, which makes the old turn more youthful. And (this is where it gets a little monstrous), if the reverse is applied, the tests proved that it makes the young mice effectively grow prematurely old.

However, the scientists were still not sure exactly what compound caused these effects. However, the newest papers from Harvard and Stanford reveal that the component is GDF11. The researchers injected this protein into mice and discovered that it ignited the growth of blood vessels and neurons in the brain. Ultimately, researchers hope that these experiments will lead to studies involving human test subjects in order to determine if there is a human equivalent of GDF11, or if there is a similar molecule in the blood of young people that can help rejuvenate older humans. “We can turn back the clock instead of slowing the clock down,” said Dr. Toren Finkel, director of the Center for Molecular Medicine at the National Heart, Lung and Blood Institute. “That’s a nice thought if it pans out.”

Researchers also assert that this may help reverse the effects of Alzheimer’s disease and other serious ailments. Of course, there is still a ways to go before we will come to human testing. Harvard’s Department of Stem Cell and Regenerative Biology (HSCRB) stated that they hope to have GDF11 in human clinical trials within three to five years. But for those of us who will be around for that long, the future just got a bit more exciting (…and maybe a little creepier).
Click to expand...

Anyone know anything more on this?
 
The scientists wondered what would happen if the stem cells were bathed in a river of young blood. Okay, so that last bit was a little heavy on the figurative language.
Click to expand...

Mofo, that was not a figurative statement, that's exactly what they fucking did, hence a bit literal in a creepy way.
 
Here's a more extended post on the same story, with pictures of some conjoined rodents (that work didn't die in the 50's apparently), in case any of you need fodder for a new nightmare tonight:

http://www.dailytech.com/Cutting+Open+Rats+and+Sewing+Them+Together+Offers+Clues+to+Fountain+of+Youth/article34857.htm

Some parabiotic (conjoined) mice:
NSFW:
Parabiotic_Mice_Wide.jpg
 
endotropic said:
Some parabiotic (conjoined) mice:
NSFW:
Parabiotic_Mice_Wide.jpg
Click to expand...

unsure if i'm only one who clicks that and gets error 'no specified link' or something... anyways this way works from my browser:
NSFW:
Parabiotic_Mice_Wide.jpg

err, ok that did work, til i threw the nsfw tags on it and then it gave same error as endo's post gave me..
Here is a NSFW link as i don't care to figure out why his/mine work w/ image tags, but not image&nsfw tags: http://images.dailytech.com/nimage/Parabiotic_Mice_Wide.jpg
 
bmxxx said:
unsure if i'm only one who clicks that and gets error 'no specified link' or something... anyways this way works from my browser:
NSFW:
Parabiotic_Mice_Wide.jpg

err, ok that did work, til i threw the nsfw tags on it and then it gave same error as endo's post gave me..
Here is a NSFW link as i don't care to figure out why his/mine work w/ image tags, but not image&nsfw tags: http://images.dailytech.com/nimage/Parabiotic_Mice_Wide.jpg
Click to expand...

They both work for me, your browser might have a problem with NSFW tags, or really really doesn't want you to look at those mice.
 
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i've had computers that wanted to sabotage me b4 but this one probably isn't one of them, my guess is just probs from all the 'security' add-on shit i have lol.
 
yeah i suggest saving money to buy young blood donors in the future. in fact, with the overpopulation occurring at even faster rate annually that can be a good thing. adopt a bunch of kids, sell some as blood donors to others for profit, keep some for yourself.

anyway, im starting the fund. if anyone want to invest, msg me
 
Well I am pretty much an old hag but I tend to date pretty young guys (they are the only ones who hit on me, I guess the older ones are all married or exhausted from kids or something.) So I am going to tell my lover about this and then explain to him what I want for my birthday......half his blooooood
 
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