Phosphorus attachment to Psilocybin chemical Structure

[nemesys]

A thousand times yes.

Plus it appears psilocybin has terrible affinity for 5ht2a compared to psilocin - PDSP certified data of >10000 nM.

Could you please provide a link to your reference for this figure? This is very interesting...

 

[specialspack]

Follow that link in the post above to the PDSP website - you can search the Ki database with ligand name.

 

[crOOk]

Phosphorus houses the Gaian energy when it bonds with your pineal antennae. Duh.

This. Your proteines don't really care that much what elements are contained in the ligand. Some ligands are larger, some are smaller, some are more electronegative on one end, less polar on the other and so on. There's nothing that special about phosphorus, the size and shape and distribution of charges is much more important.

 

[yaesutom]

Well too bad they don't have 4-aco-dmt on that PDSP website...

 

[SeenSoFar]

Well too bad they don't have 4-aco-dmt on that PDSP website...

4-AcO-DMT was very obscure until quite recently. Frankly I would have been extremely surprised if it DID have entries in PDSP, considering I don't recall ever reading a single journal article that examined it in any detail, or even mentioned it in more than a passing context. Give it time, don't forget that the "research chemical" industry is on the cutting edge of psychedelics research. People in our community, myself included, are regularly imbuing substances that have never before entered a member of our species, or in some cases (a few cannabinoids come to mind first) have never even been known to science before popping up for sale. The scientific establishment takes a bit of time to catch up, but eventually we'll see entries for all our favourite comestibles in that database.