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The Big & Dandy 5-APB Thread

Well this is my first time posting on this forum and the first time I tried this drug. I tried it with some friends on Wednesday night. We each took 100mg. After 20 minutes there was quite an intense come up with waves of nausea. Once that subsided the fun started. I've never experienced anything like it. The only way I can explain it is that the trip was like a complete shroud that could be used against your enemies in a war. For a number of hours (20) I thought a number of strange things. I thought that I was tasked to save the world. I was a secret agent you see. I had to keep the American presidents family safe as they knew the secrets of everything. I can remember telling my friends that I was ready to kill them, myself or anyone else that tried to stop me. I knew this would never happen but I felt so real. I thought that I destroyed Australia and had made it a non country taken in by the wastes. I placed my two friends there to roam around and collect buckfast bottles for eternity. I thought they'd like it? I didn't just think these things I could see them! It was amazing. I also felt huge anticipation that I was ready to either give or receive a round of applause but I wasn't sure which. I also was trying to introduce a new friend to the group called nail file? She was very posh and no one liked her. The whole thing was mad and weird. I was frightened and just accepted these things as a reality because I could see them. Usually when I trip I can distinguish that things ain't real but this time no ways. I'm not sure if I would do it again since I had to call in sick for work today (Friday) but I would recommend it if you want to go save the planet, ride a chocobo or feel like you are a computer game hero. My iPhone was also an inspector gadget phone which had all sorts of tools in it although I had forgot how to use it....
 
It's now the afternoon after the two days ride. I feel ok. Mild tummy aches. No headache. Feel very tired but don't feel like I want to throw myself off a building. Apart from the sore tummy if I really had to I'd get up and do stuff.

I'd recommend it if you have three or four days off. Also I was just reminded that we each took x3 doses of 10mg spaced around 3 hours apart. I cannot remember this. I would never do it outside or clubbing or around a tone that might get offended by nonsense talk.
 
Can anyone tell me if 5-APB.HCl looks just like the old succinate batches? I suspect I may have been duped.
 
sorry, I didn't follow the thread, and now it's too long for me to work through. can someone sum up the similarities and differences of 5-APB and 6-APB? I know this was already diskussed extensively, but if there were any short conclusions, it would be nice if someone could tell em to me directly.

what I have realized so far is that 6-APB most likely acts similar as MDA, i.e. as both 5HT2A-agonist (i.e. psychedelic) and triple monoamine releasing agent. I assume 5-APB to be quite similar, but with small shifts in the prioritys it sets. so the best short answer I can expect would be the answer to the question: does 5-APB go more into the serotonin releasing direction, compared to 6-APB or more in the noradrenaline/dopamine direction? or are the differences more subtle at all?

and, finally: can a rational argument be given that many people seem to prefer the combination of the two over either one of them alone?
 
There's a good comparison here:
I've tried both 5 and 6 on several occasions and have tried them both together once. Not sure I agree with Frequent Flyer.

Euphoria:5APB - 4. Euphoria is there but the whole experience is much more lucid and functional than MDMA. 6APB - 7. Much more euphoric. Really lovely feeling - particularly with doses of 6APB above the 100mg range.

Stimulation: 5APB - 8. This is where I don't agree regarding sedation. This stuff gave me so much energy, a wonderful clean feeling. Was at a club night for 8 hours, had 70mg of 5APB to begin with a small top-up (30mg) after a couple of hours. Going all night, lots of dancing. 6-APB is so much heavier. Wouldn't want to rate it. However, I have not tried it in a club - I'm going to this weekend. I'm hoping that, mixed with 5APB, it is going to be a lot of fun.

Empathy: 5APB - same with euphoria. It is there but 5APB was all about energy and lucidity. I wanted to talk to people, interact, kiss my girlfriend etc but I was perfectly happy just dancing and enjoying the feeling. 6APB - 8. Very close to MDMA at a dose of 150mg - nothing beats MDMA - but very close. In fact, the empathy I experienced during my last little experiment with 6APB allowed me to make a major breakthrough with regards to the thesis I am writing.

Tactile Sensation: 5-APB - 5, 6-APB - 6. Both quite similar. The functionality and lucidity of 5APB leaves it a little wanting in comparison to 6APB.

Visuals: 5APB - eye wobbles, nothing more. 6APB - OEVs, CEVs, light, colour enhancement. Probably about 3 out of 10. However, mixed with weed and MXE, 6APB gets very, very, very trippy - be careful not to take MXE too close to the peak. With that combo 6APB comes up to a 6.

Music Enhancement: Both excellent, nearly up there with MDMA.

On the occasion I tried 5 and 6 together, it was very apparent that the former is so much more potent than the latter. You need much less 5APB to roll than you do with the 6. 50mg of 5APB totally overpowered about 150mg of 6APB.

However, I bloody love 5APB for a couple of reasons. It is clean, crisp and bursting with energy. It has enough empathetic and euphoric qualities to make socialising (in a club seating) both easy and enjoyable. In addition, I have not had any comedown after taking 5APB. I don't really think you get any with 6APB either.

The plan for this weekend is to start with 100mg of 5APB (which I wouldn't recommend unless you've tried this stuff before) and then to top up with 80mg of 6APB. My hope is that I'll have the energy and drive from the 5APB coupled with some enhanced visuals from the 6APB. As ever, a trip report will follow sometime next week.
Click to expand...
 
thank you Transform; so you consider this comparison representative, and many others have said similar things?

in my naive understanding of psychopharmacology, this sounds like 6-APB is reasonably active as 5HT2A-agonist, and a balanced releaser of all three monoamines, but a little bit more on the dopamine side, while 5-APB is weaker as 5HT2A-agonist (hence the lack of visuals) and NA/DA releaser (thus the lack of stimulation), but more active as serotonin releaser. combining the two will give you no vastly different effects, but a little more balanced monoamine release. does this make sense?

and with the dihydrogenated versions, this trend seems to become even stronger, with 5-APDB being a SSRA, and 6-APDB a full entactogen, but also more on the dopamine side? (I've read reports of people even preferring 6-APDB over 6-APB).

but with N-methylation everthing changes, and 5-MAPB seems to be superior to 6-MAPB?
 
120mg 5-APB succinate.
Bombed in a gelcap on empty. Angry mood going in.
30min in, puking.
1 hour in, jaw chattering uncontrollably for about 2 hours. Very vague LSD-like patterns in visual field.
Eyes dilated.
Lasted about 8 hours. No euphoria or even mood lift. Did "open up" emotionally = crying & talking.

From the same batch that gave me a nice euphoric trip at half dose.

Felt more depressed than usual 2 days later. (I'm a clinically diagnosed depressive. Not taking any SSRI or meds.)
 
Okay so I've read the last 12 or so pages and have only found a couple of posts about plugging so I'm gonna straight up ask in hopes that more people have tried this ROA, is plugging feasable with 5-APB? I'm only gonna have 1 day available this weekend an really wanna give 5-apb a go but can't afford to lose sleep so I'm wondering what the timeline and dose for 5-APB plugged is? I'm looking for a shorter experience with a greater rush and plugging seems to be a better way to achieve this than insufflation. If nobody answers I'll likely give 65mgs a go. I have the HCL and it's said to be 98% purity. I don't know whether it's soluble but I will add vinegar and heat if it turns out not to be.
 
So the HCl doesn't cling to the bag? I just got some and I'm not sure when to take it. Will it make me depressed or not? I still have M1 in case this isn't better than that. M1 I had 0 side effects until I ate a tramadol and made myself have SS.
 
40mg MPA in a gelcap on empty - nice for 4 hours - chores get done - slow trail off
next
70mg 5-APB hlc in a gelcap on empty - talked & cuddled/stroked with my sweetheart about 6hrs - enriched my connection to her. No intense MDMA like euphoria I got with 5-APB in the summer of '13 - but no need for it. No dancey energy, but a strange languor. Regular need to drink (water).

3 hours after this conversation, a slow, dysphoric come-down begins. She sleeps (thankfully) on a benzo. Had 3 of my own blues so far and still awake, strong jaw flexing & nothing to chew on (but my fist, boo-hoo).

Annoying that I can't sleep and mind is racing. Otherwise, was a close & loving night with my lovely woman.

EDIT

horrible hangover nxt day - from head to shoulders.
 
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Dosed 100mgs of 5-apb an hour ago and I just took 20mgs of 4-ho-met, I'll let you guys know how this combo works out ;)

Edit: So I ended up doing 130mgs of 5-APB, 30mgs 4-HO-MET, and 20mgs of 2c-c and had a blast. Only thing that I didn't like was that the psychedelics seemed to be fighting with the 5-APB. I popped the metocin about an hour and a half after the 5-APB and as the trip started coming on I could feel the euphoria from the 5-APB weaken a bit and the visuals from the 4-HO-MET were weaker than they should've been had I taken it alone so I tried to step it up by rectally administering 20mgs of 2c-c and tbh that didn't do much. Overall though it was a very colorful and euphoric combo, no real stimulation though, seems like a good 'chill at home' combo. Another thing I noticed that like MDMA, the 5-APB seemed to lighten up the headspace. At no point did I have a single trippy thought but then again metocin and 2c-c are both very gentle chemicals so take that for what it's worth. Duration was about 7-8 hours and I feel 100% today, no comedown or drained feeling and hopefully no depression but that symptom typically doesn't show till around day 3 or so.
 
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5-APB does have an affinity for the psychedelic receptor, and the large doses would explain why it overpowers other psychedelics that have more intense action at the receptor.
 
5HToInfinity said:
5-APB does have an affinity for the psychedelic receptor, and the large doses would explain why it overpowers other psychedelics that have more intense action at the receptor.
Click to expand...

Maybe but TBH I don't find 5-APB that much more psychedelic than MDMA and it's certainly less psychedelic than MDA and both of those combine nicely with psychedelics. Perhaps I waited too long to add in the psychedelics and the 5-APB created a tolerance barrier, either way I had a blast.
 
http://www.sciencedirect.com/science/article/pii/S0278584613001875

"This study was undertaken to examine the pharmacology of 5-APB in vitro" and highlights from its conclusion consists of: 5-APB displaces radioligands at the dopamine transporter and 5-HT2A receptor.
• Real-time assessment of 5-APB on accumbens dopamine suggests amphetamine-like effects.
• 5-APB contractions of rat aortic preparations suggest potential hypertensive effects.
• 5-APB contractions of rat fundus predict potential valvulopathies.

"Thus 5-APB's pharmacology is consistent with it having both stimulant and hallucinogenic properties. In addition, 5-APB's activity at the 5-HT2B receptor may cause cardiotoxicity."
 
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