Having a huge drug rotation to avoid tolerance?

[sexypizza]

Hey guys Ive been thinking about this for a while now.

Is it possible if you had a lot of different drugs with you, say 12 to 20 and then rotate each one for a different day, theoretically, if you knew what you are doing and avoided all the health risks, contradictions, cross tolerance, ect...ect.. wouldn't you be able get high everyday without getting any tolerance?


Ive found some guys on the web who are already doing this with kratom a thai leaf. they basically rotate 12 different strains and get minimum tolerance while getting all the benefits.

http://www.goodlookingloser.com/all-about-kratom-2

I would really like to try this but unfortunately its really hard to get kratom here.

like the guys from the website im looking to use this mainly as a social enhancer.

 

[sekio]

NsPD --> BDD

 

[mrflowers00]

i have tried but if you do the drug you like most you will do it until it's gone and wont rotate

 

[piller97]

Im no expert but IMO though this may seem viable in theory, I highly doubt it would be very effective, if at all.
All i can really imagine it doing is possibly delaying the onset of tolerance

Also, you'd have to be using a hell of a lot of variety in order to have 12-20 different drugs that don't present any cross-tolerance issues.

But this is just my thoughts.
But if you do end up doing this I would be really interested in hearing of your results.

-p

 

[sexypizza]

i have tried but if you do the drug you like most you will do it until it's gone and wont rotate

can you elaborate more? did you have your own rotation? if you did what stuff did you use how did you do it ect ect..

Im no expert but IMO though this may seem viable in theory, I highly doubt it would be very effective, if at all.
All i can really imagine it doing is possibly delaying the onset of tolerance

Also, you'd have to be using a hell of a lot of variety in order to have 12-20 different drugs that don't present any cross-tolerance issues.

But this is just my thoughts.
But if you do end up doing this I would be really interested in hearing of your results.

-p

you are probably right about this. I was thinking of adding a washout period at the end of the rotation to reset tolerance or something.

 

[revolve]

I somewhat do this but not constantly or intentionally. I consume either alcohol, benzos, codeine or ghb on weeknights (which I find have absolutely no cross-tolerance whatsoever, I haven't experienced a tolerance gain for any of these) and a mixture of party drugs like mdma, lsd or ketamine on the weekends. I get high every time. LOL.

 

[lolwhatzdrugs]

We're talking different strains of Kratom?

Since they all work on the MU receptor with the EXACT same chemical, with just quantitative levels varying by strain, doubt it, highly. They'll just vary in potency.

Or am I missing something?

 

[mrflowers00]

i tried opaties amphetamines and benzos which isn't much of a rotation but it helps until i taste that opiate rush

 

[Psychedelic Jay]

You would have to switch classes of drugs every day...

You can't do opiate, opiate ,opiate

It would still be hitting the same receptors.


It is theoretically impossible.

Most of the drugs you are going to use hit the same thing...

The reason why is that there aren't that many different drugs to have non-mainstream recreational effects.

You may have tons of different substances, but there are only 4 to 5 different subjective classes of recreational drugs that hit different receptors...

ALL build tolerance in some degree.

 

[lolwhatzdrugs]

You would have to switch classes of drugs every day...

You can't do opiate, opiate ,opiate

It would still be hitting the same receptors.


It is theoretically impossible.

Most of the drugs you are going to use hit the same thing...

The reason why is that there aren't that many different drugs to have non-mainstream recreational effects.

You may have tons of different substances, but there are only 4 to 5 different subjective classes of recreational drugs that hit different receptors...

ALL build tolerance in some degree.

Come on

Day 1 - Opioids
Day 2 - Blow
Day 3 - Meth
Day 4 - Some psychedelic
Day 5 - Any disassosiative (PCP preferred)
Day 6 - Weed Only
Day 7 - Something from not above
Day 8 - More Opioids!



QFT, WTF, You have any idea how dumb the above (my daily calendar directly above) sounds?

 

[One Thousand Words]

You would still build at least a psychological tolerance to being high or not sober.

 

[Psychedelic Jay]

Come on

Day 1 - Opioids
Day 2 - Blow <---
Day 3 - Meth<---
Day 4 - Some psychedelic
Day 5 - Any disassosiative (PCP preferred)
Day 6 - Weed Only
Day 7 - Something from not above
Day 8 - More Opioids!



QFT, WTF, You have any idea how dumb the above (my daily calendar directly above) sounds?

You already fucked up.

 

[lolwhatzdrugs]

You would still build at least a psychological tolerance to being high or not sober.

Which will probably lead to him being a poly-drug abuser for life.

You already fucked up.

My order? I wasn't being serious, demonstrating the lunacy of the idea.

Explain.

 

[JT_5]

Generally in my own experience i find that most people refer to the constant changing of substances in order to avoid negative effects like tolerance and dependency as "Changing seats on the Titanic" Unfortunately you're more than likely going to go down no matter what kind of regimen of substances you use.

A few things will happen for sure based on my own experience with attempting this kind of rotation. First of all you will find that you enjoy using certain substances more than others. Whilst for a short period of time a rotation might work you will eventually become compelled to use one substance more and more until your regimen is compromised. Second, the constant change of substances can drive you practically insane. What i mean by this is that with using different drugs every day, especially ones with largely different effects, potentially could mimic psychiatric disorders like Bipolar disorder. Going from opiates to amphetamines to benzodiazepines having used each of them for one day then switching will drastically affect your performance in different areas depending on the substance. For example, in a working environment such as an office where you're required to sit at desk and make spreadsheets all day, amphetamines would be great. The substance increases productivity and hones cognitive function while in effect. However, the next day you're on opiates, I doubt you will want to do much, let alone make spread sheets. The following day you might be on amphetamines again or maybe a benzo, your boss and co-workers will know that something is up. Your mood will do a lot of bouncing up and down and people will look at you like you belong in the loony bin. That's only going to last until you eventually enjoy one substance above others in the regimen and then it will be compromised. In conclusion, i think this isn't a very smart idea. Hope this helps.

 

[lolwhatzdrugs]

Generally in my own experience i find that most people refer to the constant changing of substances in order to avoid negative effects like tolerance and dependency as "Changing seats on the Titanic" Unfortunately you're more than likely going to go down no matter what kind of regimen of substances you use.

This.

If you're using and trying to avoid dependence, and LIKE ONE SPECIFIC THING (Your DOC), you're probably not gonna be able to resist and become a full blown addict real quick.

 

[Blind Melon]

That's a great idea in theory, but in practice never works out. Once you've tried Smack do you think you're not going to want to buy some after a Crack/Meth sesh? Do you think you'll use stims and nothing else for days, no sleep only to switch to benzos for days before something else? People will think you're bat-shit crazy, possibly schitzo. At the least bi-polar to the max. The only successful way to be a poly-drug user is to use all the classes of drugs in conjunction with one another. Wake up to an amphetamine, pop a benzo a few hours later to level out. Smoke a joint so you can eat a big dinner before bed. But be warned, down this path lies poly-drug addiction. And you don't know what kicking is until you've quit opiates and benzos at the same time.

 

[lolwhatzdrugs]

The only successful way to be a poly-drug user is to use all the classes of drugs in conjunction with one another. Wake up to an amphetamine, pop a benzo a few hours later to level out. Smoke a joint so you can eat a big dinner before bed. But be warned, down this path lies poly-drug addiction. And you don't know what kicking is until you've quit opiates and benzos at the same time.

Which is also the most dangerous way! after the benzo and joint you wash it down a beer and an oxycontin - dead.
Safer to stick to be mono-drug dependent. FAR safer.

I couldn't even imagine the last part, I know hardcore, 'seriously thinking about loading the gun in the corner and shooting yourself' opioid withdrawal, but here GABA withdrawal (Benzo/Alcohol/Barbies) W/Ds are even worse. Ickkkkkk. Makes me feel shitty thinking about it

I'm dependant on opioids, but not benzos. I'd assume you'd withdraw/taper them one at a time, unless you end up in jail? And then don't they at least have to give you phenobarbital or valium so you don't die preventing dual W/Ds?

You've experienced it? Why did you decide to CT both? Or was it not by choice?

 

[nbome in the dome]

Come on

Day 1 - Opioids
Day 2 - Blow
Day 3 - Meth
Day 4 - Some psychedelic
Day 5 - Any disassosiative (PCP preferred)
Day 6 - Weed Only
Day 7 - Something from not above
Day 8 - More Opioids!



QFT, WTF, You have any idea how dumb the above (my daily calendar directly above) sounds?

pshhh, come on man we do better than that.

day 1. Tons of weed as a little primer for the rest of the week
day 2. ketamine, dxm, pcp!!!
day 3. time to take some shrooms or lsd! Yeehaw!
day 4.coke to knock off all those trip hangovers
day 5. now that the dissociatives are (mostly?) outta your system load up on those OPIOIDS!
day 6. SALVIA BABY SALVIA ALL DAY LONG. or amphetamines. DMT anyone? Or smoke some kratom. OR BENZOS if you really wana keep your days as different from eachother as possible.
day 7. you guessed, reminisce on the wonderful week with some MDMA yo, and look forward to an identical week for weeks to come!

AND I COMPLETELY FORGOT about alcohol! haha, maybe that's for the best though... but remember boys and girls, day six is UP TO YOU!

 

[Psychedelic Jay]

pshhh, come on man we do better than that.

day 1. Tons of weed as a little primer for the rest of the week
day 2. ketamine, dxm, pcp!!!
day 3. time to take some shrooms or lsd! Yeehaw!
day 4.coke to knock off all those trip hangovers
day 5. now that the dissociatives are (mostly?) outta your system load up on those OPIOIDS!
day 6. SALVIA BABY SALVIA ALL DAY LONG. or amphetamines. DMT anyone? Or smoke some kratom. OR BENZOS if you really wana keep your days as different from eachother as possible.
day 7. you guessed, reminisce on the wonderful week with some MDMA yo, and look forward to an identical week for weeks to come!

AND I COMPLETELY FORGOT about alcohol! haha, maybe that's for the best though... but remember boys and girls, day six is UP TO YOU!

The main reason that this is an unmaintainable endeavor...

It is simply too expensive to maintain. that is potentially about a couple of grand worth of drugs in 2 to three weeks...

Also, the comedown of those dissociatives are going to affect you for the next couple days or so..

You will go batshit crazy.

 

[Viṣakaṇṭha]

This is actually something I've been doing myself for years. The thing is, it does work extremely well for avoiding addiction (which is why I do it), but pragmatically it doesn't help much in the way of tolerance. It will at first, but if you do it for any prolonged amount of time (years for instance) tolerance will indeed creep up on you.

Its possible that it could just be me, but the body doesnt seem to forget substance use that easily. For instance, after a several year heroin addiction which I had before i started rotating drugs (and which took a very long time to develop) I quit using H about 2 years. Then I visited a few friends and partook in some recreational H use and my tolerance sky-rocketed within a week alone (and this has happened with a variety of substances as well). Lol so now instead of avoiding tolerance, it does seem as if i've developed some sort of permanent tolerance to almost all categories of recreational psychoactives. But yeah, I can't disparage this method too much, because I still have a lot of fun and engage in drug use on a near daily basis without any major issues (and I can thank my drug-rotation for that in a big way)...but as far as the specific issue of tolerance goes, it really doesn't help the situation at all.