Physiological Affects of Amphetamines

[HemoStatic]

Hello, looooong time lurker, first time poster. I was wondering to what extent amphetamines affect the body. The effects on blood pressure, heart rate in the short term are of particular interest to me.

I understand that one's reaction to a drug is highly variable, but if an "average" effect on blood pressure and other effect would be appreciated. I only ask because I have read many threads that discuss such varying responses to the effects of amphetamine that it is hard to get a clear, concise answer.

 

[belfort]

amps raise blood pressure and heart rate no doubt, sometimes to a very significant degree..

 

[Jabberwocky]

They can cause a host of problems to the user physiologically. As mentioned, amphetamine can significantly raise the blood pressure and heart rate to the point of a heart attack/respiratory collapse. The illicit the body to give off more heat in larger areas of fat mass/muscle mass, but at the same time cause vasoconstriction, which can cause your body temperature to raise, but lose circulation of blood to some areas of the body for instance the feet - users often complain of cold feet on amphetamine for this reason. It also blocks the hunger response, meaning you can forget to eat and get not enough nutrients or water- which your body is using at double the amount with the drug in its system due to several factors.

They can also provide minor pain relief in some, meaning you may not feel an injury as badly as it should be - which can lead to further damage if something is busted, for instance you could sprain your ankle and "push thorough the pain" much easier. How it does this I'm not exactly sure.

Oh! And it can cause paradoxical effects on a persons blood pressure/heart rate too, as it in can lower it. I've no idea why this happens either, but to each their own.

That's all I can think of for now, but anyone else jump in.

 

[Psychedelic Jay]

They can also provide minor pain relief in some, meaning you may not feel an injury as badly as it should be - which can lead to further damage if something is busted, for instance you could sprain your ankle and "push thorough the pain" much easier. How it does this I'm not exactly sure.

Oh! And it can cause paradoxical effects on a persons blood pressure/heart rate too, as it in can lower it. I've no idea why this happens either, but to each their own.

That's all I can think of for now, but anyone else jump in.

To add to these two points.

Amphetamine creates a significant surge in norepinephrine. This leads to your body having rushes of endorphins as well. Leading to enhanced pain relief similar to you being in high danger situations.

Also, you body will try to compensate for the rise in blood pressure by slowing your heart rate and lowering blood pressure... This has been known to override the vasopressor effects.