The fluoride is bound intensely to the molecule. It is probably not responsible for the burning sensation.
Caustic and Ph balance are interrelated. , Caustic means high pH number, meaning strong base. Low pH numbers mean acidity .
Best way to find out is dissolve 4-fa in water, and get a few narrow band pH strips, and see if it is particularly caustic or acidic.
Honestly, I think that his stomach ulcers may have resulted elsewhere, or the 4-fa potentiated them.
I doubt 4-fa dissolved in water and swallowed has any too negative effects on the stomach and it's lining. But if you find out if it is acidic or caustic, that could be a reason, and neutralizing it would make it safer to ingest.
Thank you! After speaking with one of my friends, it seems that the bleeding he experienced from the plugging has stopped, and perhaps resulted from damage created while 'cleaning' the area for proper administration. After taking several days off from plugging or using 4FA (except for a very low dose plug yesterday), he still reports sharp pains down there occasionally, and are the same pains which would arise after plugging (albeit much more intensely) - but it is unknown whether the pain is related to the drug, or is related to damage created during cleaning which is aggravated by the drug. Pain does not necessarily equal tissue damage; perhaps agonism of nerve receptor sites by the drug.
I should also mention that he wasn't plugging large amounts - perhaps 30 mg at a time, several times a day for a week at a time, with several days off inbetween, over a period of several weeks.
He also apparently tried IV once, and being inexperienced in this, ended up getting it under the skin rather than in the vein. He used maybe 20 mg for this, and while it stung for several hours at the site of administration, he eventually felt quite a buzz and a slight rush at first - despite having been using 4FA for almost a week in a row already, and reporting diminished effects.
He doesn't plan on trying IV again though, due to the difficulty of administration and feeling uncomfortable with that ROA, as well as the dubious nature of this chemical in relation to it's effects on tissues.
We'll definitely look into pH testing as soon as possible
I'm also curious as to what 4FA is often cut with, as the cut may be the problem as well. I know we found table salt in some earlier batches, and then it seemed to get purer as time went on. Everything goes through one friend who has access to a lab - he tests the purity and then gives it to us. He may be cutting it, and he doesn't know we'd be doing anything with it but eating it, so, I've heard table salt has been found in 4FA quite often and we also found that at one point - is anyone aware of other popular cuts for 4FA? I'm sure people could cut it with just about anything..
And would one be able to easily (without special lab equipment) purify 4FA by, for example, mixing with water and recrystalizing it somehow?