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Do psychedelic benzos exist ?

B

BottleDryer

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Jan 21, 2012
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Do they ?
Like say something like a psychedelic substance with anxiolytic effects ?

Anyone know of anything like this or similar ?
 
No. But dissociatives tend to have anxiolyitic effects. I don't think traditional serotonergic psychedelics could ever be considered anxiolytic.
 
It's feasible for a psychadelic to perhaps activate GABA receptors and thus have a mild sedative (and thus anxiolytic) effect, though I'm not aware of any with significant GABA receptor action.

Interestingly, there are a few anxiolytic drugs that work through the 5HT1A receptor (a serotonin receptor), most notably Buspar (Buspirone). Many psychadelics affect this receptor, LSD and MDMA being the most common full agonists (Psilocybin is only a partial agonist). Thus they may technically have a mild anxiolytic effect, though this may be overcome by the sheer intensity of the experiences for some.
 
Orally ingested cannabis can have the sedating, muscle-relaxing and anxiolytic properties of benzos while at the same time being psychedelic.
 
Yes. Valerian Root.

This varies per people. But people who it is active for will have a psycedlic-esque experience from large dosages. Moreso an empty trip. Similar to low dose mushrooms without the headspace.
 
Does Valerian contain a benzodiazepine? I've often wondered about its mechanism of action.

What about Z-drugs? They're non-benzodiazepine hypnotics that activate the same receptor, and they have been known to produce near-psychedelic dream states.
 
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The only ones I've experienced are definitely NMDA antagonists, mainly ketamine.
However when you do enough ketamine to get psychedelic effects like visuals, it usually becomes far to hard to communicate with another person that I find I develop lots of anxiety unless around people who are also on ketamine
 
Interesting.
Is there a foreseeable future were a designer drug with a combo of RC benzo's and psychedelics will / can be produced ?

Would that work effectively ?
 
^That seems like it would be somewhat pointless as most benzos greatly dull the psychedelic experience. I wouldn't call it a full blown psych but Ambien seems to have some psychedelic qualities and it greatly potentiates other psychs. LSA usually doesn't do much for me but a hefty dose of HBW and some ambien produced some strong OEVs.
 
^I wouldn't really call ambien's effects psychedelic, it's more of a deleriant in my oppinion.

Never Knows Best said:
Amanitas Muscaria is a GABA receptor agonist, psychedelic (in the adjectival sense), and found to be anxiolytic by some persons. Otherwise, NMDA antagonists fit the bill pretty well. I wouldn't count on any serotonergic psychedelic reliably exhibiting this effect in acute administration.
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If anyone here has actually tried amanita muscaria I'd be very much intrigued to hear about the effects. Last week I was out to pick mushrooms (the ones you eat, not get high on though) and saw some chick picking up all the amanitas. I wanted to ask her about them, but I am unsure if they could actually be used in cooking or something else so not wanting to seem like an idiot I just walked right past her.

BottleDryer said:
Interesting.
Is there a foreseeable future were a designer drug with a combo of RC benzo's and psychedelics will / can be produced ?

Would that work effectively ?
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If you want a psychedelic benzo experience all you need to do really is take your psychedelic of choice and add any benzo available. It will cause a more relaxed and less intense experience.
 
Toz said:
^I wouldn't really call ambien's effects psychedelic, it's more of a deleriant in my oppinion.

If you want a psychedelic benzo experience all you need to do really is take your psychedelic of choice and add any benzo available. It will cause a more relaxed and less intense experience.
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I do agree on the delerient effect of ambiem more so than a psychedelic effect.

As far as a "psychedelic benzo experience" I was hoping there was something out there that people experienced that had the qualities of both worlds in one package. I don't have much experience with psychedelics other than salvia and marijuana (if you would call that a psy).
 
^How many seeds were you working with? I've noticed the same effect at low doses, but at higher doses patterns take on lives of their own.

Toz said:
If anyone here has actually tried amanita muscaria I'd be very much intrigued to hear about the effects. Last week I was out to pick mushrooms (the ones you eat, not get high on though) and saw some chick picking up all the amanitas. I wanted to ask her about them, but I am unsure if they could actually be used in cooking or something else so not wanting to seem like an idiot I just walked right past her.
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You should have said hey! I bet she was good people. It's pretty rare, but some people do cook with them. Remember though, they are poisonous until thoroughly boiled or pickled (or dried if you wish to retain the psychoactive compounds)!!

BottleDryer said:
As far as a "psychedelic benzo experience" I was hoping there was something out there that people experienced that had the qualities of both worlds in one package. I don't have much experience with psychedelics other than salvia and marijuana (if you would call that a psy).
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MXE has been described as a psychedelic dissociative with strangely anxiolytic qualities similar to benzos or opioids.
 
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Toz said:
No. But dissociatives tend to have anxiolyitic effects. I don't think traditional serotonergic psychedelics could ever be considered anxiolytic.
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Enix150 said:
MXE has been described as a psychedelic dissociative with strangely anxiolytic qualities similar to benzos or opioids.
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I agree, I think what the OP is looking for is usually known as a dissociative. Dissociatives can have psychedelic and anxiolytic properties. To me, MXE is more psychedelic than anxiolytic and rather stoning, whereas 3-Meo-PCP is more anxiolytic than psychedelic and much more lucid. But both are relaxing and have a psychedelic edge. I can't speak for traditional dissociatives, like K or PCP though, as I have zero experience with them. The OP might be interested in checking out arylcyclohexylamines.
 
It seems as though you're interested in psychedelics, but you're afraid of the anxiety and "bad trips". Please don't be! They are wonderful experiences, bad trips really aren't what they're depicted as. But to answer your question; there are no real serotonergic psychedelics that also affect anxiolytic receptors in the brain.

There are some in a gray area though:
Dissociatives; like ketamine and MXE. But others like PCP, DXM, and Salvia are usually considered opposite of anxiolytic.
"Z-drugs"; like zopiclone, zaleplon, zolpidem. Some people report psychedelic-like hallucinations. They are also used as sedatives.
Cannabinoids; some people get a lot of anxiety with them, some people become very relaxed. Some people feel psychedelic effects while others don't. Personally I become very relaxed and it is very psychedelic for me (even visual at times).
Serotonergic Psychedelics; DMT and psilocybin are two that come to mind. They aren't anxiolytic at all, but they're extremely relaxing, blissful, lethargic, etc.
Amanita Muscaria; ugh, yes unfortunately I've tried it multiple times. Its a horrible drug. Yes you hallucinate and it can be psychedelic. Yes it can feel very sedating/dissociating. But it is not something you want to try, please don't consider it. While there are some psychoactive effects, it has more (extremely!!!!!!!!!!!-) negative physical side effects than anything.

None of these drugs other than the real psychedelics will give you the experience you're seeking, I can guarantee you that.
 
When these bad trips happen, it is good to have some benzo's lying around. Just in case, we used to call it "landing gear," doesn't make the trip stop but it makes it descent faster. Never had to use them mid-trip, but when you are coming down, benzo's make it so much easier. I like to have trip aborters (plan B, lol). Someone was tripping with my friends and my friends came to get me cause this kid was trying to kill himself and they had no idea what to do. We told him we'd let him kill himself as long as he drank a glass of water. We put ~4mg of xanax in the water and he calmed down, zoned out, and fell asleep. It was a risky thing to do, but both drugs combined are much safer than trying to physically prevent him from killing himself while tripping balls.

One of the other things I noticed is that when people take benzo's before a trip, it kinda defeats the purpose. Trips are supposed to be intense and profound. So I doubt a relaxing psych would be that great.

Has anyone here ever tried mescaline. I did a huge dose once, and even though I was tripping balls, I was calm, happy, collected, and my mind was relatively clear. Despite being a phenethlyamine it wasn't very stimulating.
 
The answer is simple NO.

No psychedelic has a fusion between a benzene and diazepene ring.
anxiolytic effects - maybe

RhythmSpring said:
Orally ingested cannabis can have the sedating, muscle-relaxing and anxiolytic properties of benzos while at the same time being psychedelic.
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The only problem here is your not differentiating between Sativa, ruderalis or Indica.

I would say smoking or ingesting a Indica dominant or pure Indica would help alot better than a powerful Sativa.
 
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