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Opioids Change in Oxycodone tolerance after 3 weeks abstinence?

Oxy8_8

Bluelighter
Joined
Apr 24, 2013
Messages
489
Location
England
I took an average of 300mg a day of oxycodone - a combination of "roxi" instant release capsules and OC OxyContins which I would either chew or crush up and insufflate (always peeling off the time-release coating first) - for 6-7 months before my doctor discovering and booting me off to a methadone clinic as a Day Patient. Despite the relatively high dose of Oxy, I have only been on 35mg/day of methadone for the last 22 days. I'm also addicted to Xanax, which I have continued to use throughout, which probably helped with my opiate detox and masked a lot of the WDs, hense the low methadone dosage.

Anyway, according to my doctor at the methadone/addiction clinic, by now I will be back to having the same opiate tolerance as someone who has never taken an opiate in their life (i.e. my tolerance will be 0, apart from 35mg methadone a day, and I would die of an OD if I went back to my old amounts).

Is this true? I just got myself 10 OC40s. Could taking like 3 of them throughout the day really either kill me or have me totally monged out?

I was planning on insufflating 20mg oxy to try first?

Can anyone please help? Can anyone offer a guideline of what my tolerance would be or what would be a safe amount to take? Even if it's just something like "take X amount and then add no more then 10mg at a time and wait at least an hour between each time you re-dose"?

Please keep in mind I'm also on benzo's and due to having a newly decent supply will go back to my usual 2.5mg/day (0.5mg in the morning, 0.5mg in the afternoon, 0.5mg in the evening, 1mg at night) instead of the 1mg/day I've been taking recently due to running very low.

I know it's advisable not to take both, but I'm asking on bluelight where I think quite a few of us mix them and this is a place where we never judge each other, right? Plus I suffer severe chronic pain (acute pancreatitis and rheumatoid arthritis) as well as almost crippling anxiety and panic attacks. So - although I abuse them - I do actually NEED them both.
 
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If one could go from junkie tolerance to opiate naivety in 22 days of abstinence, junkies all around would rejoice. Add in that your receptors are still being saturated by methadone and chances are that you will have a tolerance far above your doctor's recommendation.
Obviously, you will experience some drop in tolerance, so play safe.

But, if a medical professional believes opiate tolerance can be removed with 22 days of bombarding the receptors with a drug of the same class, they should have their license revoked.
 
If one could go from junkie tolerance to opiate naivety in 22 days of abstinence, junkies all around would rejoice. Add in that your receptors are still being saturated by methadone and chances are that you will have a tolerance far above your doctor's recommendation.
Obviously, you will experience some drop in tolerance, so play safe.

But, if a medical professional believes opiate tolerance can be removed with 22 days of bombarding the receptors with a drug of the same class, they should have their license revoked.

^^I figured as much. That's why I asked on here. It seemed like my doctor was giving me some pretty dubious information.
So what do you reckon? Should I half my previous dosage?
I figure the doc was a) trying to cover me her ass incase I I OD'd and my parents sued her and/or b) trying to scare me away from relapsing.
 
he's probably not incompetent, so much as he just doesn't want you to relapse.
It's probably more to scare you straight, than to try to give you scientific advice. 35Mg methadone is something close to like 10mg q 6hrs OC oral. :?

Are you sure you want to start doing OC again and go down that path? Isn't that what fucked your life up last time?
Why don't you stick with the methadone maintenance ??
It also sounds like your xanax/benzodiazepine use is increasing....

These are supposed to medicines that you need to function with your conditions! If you get back into abusing them they will not work for you and will cause you problems.
 
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