Do you have a ''nodding special'' drug combo that doesn't include any strong opiate?

[weekend addiction]

Mirtazapine has downstream opioidergic effects, very interesting.

Can you please explain? I could google the answer but I want everyone to know what your talking about.

 

[dankhead88]

According to the wikipedia article, I'm going to guess that mirtazapine as somewhat of a similar side effects to opiates. I saw constipation, somnolence, sedation, and other similar side effects.

Only time I ever nod off other than heroin is from sleep deprivation, or sleep deprivation caused by meth.

 

[Longhauler]

Well popping a tricyclic antidepressant just to knock yourself isnt a great idea now is it, really? Dont take them unless theyre scripted for a purpose.

I do have a script for Remeron. I used it every day for a couple months. It did improve my depressive symptoms for a while but somehow ''pooped out'' as an antidepressant and made me grow a little belly due to a phenomenally increased appetite... So I stopped using it daily, but still find its powerful anti-emetic & antihistamine effect very useful when combined with high doses of kratom (as an alternative to orphenadrine, for example) and it is great in various analgesic/sedative combos.

 

[Longhauler]

tramadol and temazepam with a bowl of some nice indica and you're fucking in there.

I agree, but temazepam is a big nono for me.

coffe and weed

Yeah, somehow that combo relaxes me, but it won't ever make me nod.

 

[Longhauler]

Thanks for all your suggestions guys

Mirtazapine has downstream opioidergic effects, very interesting.

Yep! That's why I think it's the best antidepressant for opiate withdrawal.

Tramadol, bromazepam and weed.
Or
Tilidine, bromazepam and weed.

Both are awesome, highs. They can both give me a strong nod, but I usually don't get so faded that I can't snap out of it should I want to. Sometimes though, when tolerance is low, the tilidine can really knock me on my ass.

The tilidiine combo is very reminiscent of an oxy high.

Tramadol + tilidine isn't a very good combo I've found.

I never tried tilidine, you lucky bastard don't think it's even available in North-America.

Buprenorfine and phenibut and weed , throw in some l-theanine , guta kola, and possibly some sedative anti-histamines.


note burprenorphine might not be technically a weak opiate , but due to it's partial agonist/antagonis effects I think I can argue it's not very recreational (read sedative) in a maintenance context and thus a "weak" opiate for me.

I love ''energizing'' opiates like tramadol, tapentadol or even kratom, so I would be pleased with that combo for sure! Phenibut is also a great opiate potentiator and sedative combo booster! Thanks for the suggestions.

I've also noticed that large doses of GHB can have me nodding in and out, but that does not normally happen until I hit about 5+ grams or so.

Yeah GHB is one hellava substance... i do like it, but find it a bit overwhelming lol I tried it a couple times, and each time I went from strongly inebriated to comatose with no intermediate nodding session lol. In short: its low therapeutic index makes it hard to dose optimally, but it sure is a drug that I'd like to have a nice supply of to experiment!

Never had an opiate nod, but I had an experience closely matching what you want last night...

What I took:

* 60-70 mg dextromethorphan (taken very slowly throughout the day)
* 1200 mg gabapentin (taken in four doses over a couple of hours)
* several small glasses of vodka (enough to reach tipsy)
* 1.5 mg melatonin (dose estimated; I eat fractions of pills so I can get to sleep, but still remember my dreams)
* 25 mg diphenhydramine
* a few hits of cannabis (Blue Cheese strain) through the day, more right before bedtime
* music (the Nintendo DS isn't the best mp3 player in the world, but it does the job)​

After laying down and putting on some of my favorite music, I took a couple good hits of pot. My body felt wonderful; that is, I couldn't feel much at all (no pain) I knew I was in for a rough time at first (Blue Cheese is a potent strain), but with everything else I was able to get right into the mindset I needed to be in, and the everything turned out just fine :D

Wow dude! That's a nice mix lol. Something close to it could also please me... but I wouldn't include dextromethorphan in a ''nodding'' combo, personally: dxm can get me wired up pretty bad.. I prefer it (in moderate doses) in stimulating, morning combos. And as for vodka, as I said earlier, my bowels can't stand liquor too much, and I fucking execrate hangovers. Nowadays I drink in extreme moderation, never getting hammered with booze.

Can you please explain? I could google the answer but I want everyone to know what your talking about.

Well, I wouldn't be competent enough to give you a full scientific explanation, but it seems that mirtazapine indeed has opioid activity. In my non-placebo-effect experience, it DOES help alot more than other antidepressants in opiate wd, which is proof enough for me that it does induce the opioid endogenous system as it is claimed in some scientific papers. It is also the best anti-emetic ime. Prolonged daily use ain't a good idea cos it will make you gain weight, etc. For ME tho, it's the best AD I've come across, with the fewest nasty side-effects, and I'm not a big fan of AD drugs..

According to the wikipedia article, I'm going to guess that mirtazapine as somewhat of a similar side effects to opiates. I saw constipation, somnolence, sedation, and other similar side effects.

Only time I ever nod off other than heroin is from sleep deprivation, or sleep deprivation caused by meth.

Mirtazapine actually constricts the pupils, contrary to most other AD - another indication of its centrally-acting ''opiate'' (or at least strong sedative) properties.

Clonidine also has a pupil-constricting effect lol... In fact, I get microscopic dots instead of pupils with my ''nodding special'' combo, the same spaced-out look I get with a good dose of hydromorphone or oxy... I love it! lol.

 

[dopemaster]

Benzos, Z drugs, and Barbituates mixed together are sure to do it. MJ cant hurt. Muscle relaxers and DXM are chill. Booze will always calm you down but makes you wake up in the middle of the night IME. I personally mix a lot of drugs together which I really don't recommend and can be dangerous but its a risk I chose and I proceed with caution and work my way up, as well a researching every drug I choose to use. I find it extremely important to know a thing or to about a drug if Im going to do it.

Also muscle relaxers will slow you down. Though they are not a narcotic they will loosen your body up. I should mention the suppress your respiratory system and the first time I took soma I actually overdosed. Other drugs where involved but nothing I wasn't taking daily and nothing in larger doses. I had no tolerance and I just kept taking them because I didn't feel it. Thing was I felt completely sober but I couldn't walk. I kept trying to walk to the bookshelf to get a book and never made it.

Fiorcet is the only Barbie that's readily available. Its used to treat migraines and boy do some of my friends have migraines. Its contains butabital, apap, and sometimes codeine. I know codeine is an opiate but butabital is not and well fiorcet usually has codeine but not always it just depends whether its fiorcet or fiorcet plus. Barbies sure make me zone and nod. I had ended up taking them everyday for a few years and well it was pretty horrid when I stopped taking them. Barbituate wd can kill you, but that's usually when a person develops a daily habit.

Z drugs and hypnotics are pretty noddy. I like ambien. I also found I could jet up ambien but it didn't look to healthy. The effects were strong. Still very risky.

Some benzos that are meant for sleep like temazepam and dalmane have the hypnotic qualities of Z drugs.

Benzos are always off the chain IMO. If you got tolerance I prefer to take a bit of each one. I usually go for some Klonopin, Xanax, Temazepam, Dalmane, and Ativan. Xanax and Klonopin are my favorites by far. I know that's risky and by no way at all do I recommend any of these drugs, mixing these drugs or methods of use.

Im a big fan of DXM. It doesn't knock me out, but it makes me trip my balls off. In small doses its a bit different and just kinda amplifies and distorts my perceptions. Its not bad stuff IMO. Obviously if you take enough you will hallucinate for a long time. Its a lot stronger of a drug then some people realize as its OTC.

Strong antihistamines like hydroxyzine and promethazine will make you drowsy and are commonly used to potentiate opiates. I used to mix Benadryl powdered capsules with my morphine shots. Im sure everyone knows it but Ill go ahead and say its not that healthy to shoot pills. Some people IV Benadryl and I hear it makes you trip. Ive only slammed a small amount to take the pins and needles off morphine so I don't know personally. Promethazine is very strong, potentiates the hell out of codeine straight doubling it, and has hallucinogenic properties.

Clonodine is a strong heart medicine and used typically for detox. Ive used it with cocaine to take the bite off the heart pumping so hard. Its a drug you cannot take a lot of for a few days and then stop taking without a bit of a taper and also its very strong. I personally wouldn't use it recreationally.

Some people like kratom. Im not sure if its an opiate or what the deal with it is. I don't think its a full mu-agonist. Someone correct me if Im wrong. If I take a lot I feel something along the lines of a bit of energy on the slightly trippy side but less trippy than mj by far. I find it rather subtle and weak but some people love it.

Im a fan of vapor rub inhalers even though they are technically a stim they calm me down to just inhale them through my nose as directed. Stims and coke actually relax me for some strange reason. But that's just me for the most part. Also sudaphed is a stim most people don't recognize. I knew a guy who played football in college and he would eat a whole pack of suda tablets before a game.

Then there are inhalents like glue which Ive enjoyed since childhood but haven't really messed with lately. I like em but to each their own. Also whipits you can buy at the headshop will send you into la la land for a quick bit, but they wont make you nod long term and would be counterproductive unless you just want a short term space out. It only last a short amount of time. Maybe a minute; Im not sure as its been so long. Its kinda like you gotta keep doing em. They call it hippy crack. Usaully these drugs make you feel like shit in the long run if you use em alone and they make not be too good for your health tbph.

Booze cant hurt if you trying to mellow.

 

[exists]

Wow dude! That's a nice mix lol. Something close to it could also please me... but I wouldn't include dextromethorphan in a ''nodding'' combo, personally: dxm can get me wired up pretty bad.. I prefer it (in moderate doses) in stimulating, morning combos.

Well 60-70 mg spread throughout the day doesn't cause excess stimulation, but does help make the cannabis trippier

OK so maybe you'd just want to try this combo:

* cannabis
* melatonin (dosage is crucial, if you want to maintain a nod for any length of time)
* diphenhydramine (25-50 mg is good)
* gabapentin (whatever dose seems right, can be stimulating)
* mirtazapine
​

All those things combined should produce a pleasantly ambivalent yet useful mindspace. DPH and mirtazapine are oneirogens (dream enhancers), and the others can be trippy so you're likely to get some nice hypnagogic imagery whilst nodding happily.

Im a big fan of DXM. It doesn't knock me out, but it makes me trip my balls off. In small doses its a bit different and just kinda amplifies and distorts my perceptions. Its not bad stuff IMO. Obviously if you take enough you will hallucinate for a long time. Its a lot stronger of a drug then some people realize as its OTC.

I think a big reason why so many people hate DXM is because they took too much, and the trip wasn't what they had envisioned it would be like. You can easily become really wasted on it, yet not have any hallucinations. But when used for its enhancement/antidepressant qualities it can be quite amazing. To enhance other drugs you really only need to take about 1/16-1/4 the amount needed to reach the 1st plateau.

 

[Longhauler]

Also muscle relaxers will slow you down. Though they are not a narcotic they will loosen your body up. I should mention the suppress your respiratory system and the first time I took soma I actually overdosed.

Fiorcet is the only Barbie that's readily available.

Benzos are always off the chain IMO. If you got tolerance I prefer to take a bit of each one. I usually go for some Klonopin, Xanax, Temazepam, Dalmane, and Ativan. Xanax and Klonopin are my favorites by far. I know that's risky and by no way at all do I recommend any of these drugs, mixing these drugs or methods of use.

Im a big fan of DXM. It doesn't knock me out, but it makes me trip my balls off. In small doses its a bit different and just kinda amplifies and distorts my perceptions. Its not bad stuff IMO. Obviously if you take enough you will hallucinate for a long time. Its a lot stronger of a drug then some people realize as its OTC.

Strong antihistamines like hydroxyzine and promethazine will make you drowsy and are commonly used to potentiate opiates. I used to mix Benadryl powdered capsules with my morphine shots.

Clonodine is a strong heart medicine and used typically for detox. Ive used it with cocaine to take the bite off the heart pumping so hard. Its a drug you cannot take a lot of for a few days and then stop taking without a bit of a taper and also its very strong. I personally wouldn't use it recreationally.

Some people like kratom. Im not sure if its an opiate or what the deal with it is. I don't think its a full mu-agonist. Someone correct me if Im wrong. If I take a lot I feel something along the lines of a bit of energy on the slightly trippy side but less trippy than mj by far. I find it rather subtle and weak but some people love it.

Booze cant hurt if you trying to mellow.

LOL, thanks for sharing your overall life experience with drugs dude...

I'm a big fan of orphenadrine as an opiate potentiator and muscle relaxer, or used as a sedative - and slightly euphoric - ingredient in a nodding mix.

Strong antihistamines like hydroxyzine (and promethazine to a lesser extent) are quite effective as opiate potentiators or ingredients in a nodding special, of course, but I would advise against frequent use of phenothiazines and related antihistamine/antipsychotic drugs like chlorpromazine or levomepromazine. The risk or tardive dyskinesia, hormonal imbalances, diabetes, is real! Fucking dirty, lobotomizing drugs... Too bad, cos Nozinan (levomepromazine) is EXTREMELY potent, perfect for heavy sedation - especially when mixed with opiates and/or other sedatives. I have a dozen 25 mg Nozinan pills left: They're in my heavy-duty category of drugs for nausea or restlessness: with no tolerance, they're MUCH more hypnotic than benzos!

Clonidine is not exactly a ''heart'' medecine: it's a drug to treat high blood pressure. Used alone, it has low recreational potential, but used in supra-therapeutic doses in sedating mixes its potential is quite different... I agree tho that one has to be very careful cos detoxing from that stuff can be rough.

As I said multiple times, alcohol SUCKS for me, and I don't wanna use benzos anymore.

 

[Longhauler]

Well 60-70 mg spread throughout the day doesn't cause excess stimulation, but does help make the cannabis trippier

OK so maybe you'd just want to try this combo:

* cannabis
* melatonin (dosage is crucial, if you want to maintain a nod for any length of time)
* diphenhydramine (25-50 mg is good)
* gabapentin (whatever dose seems right, can be stimulating)
* mirtazapine
​

All those things combined should produce a pleasantly ambivalent yet useful mindspace. DPH and mirtazapine are oneirogens (dream enhancers), and the others can be trippy so you're likely to get some nice hypnagogic imagery whilst nodding happily.



I think a big reason why so many people hate DXM is because they took too much, and the trip wasn't what they had envisioned it would be like. You can easily become really wasted on it, yet not have any hallucinations. But when used for its enhancement/antidepressant qualities it can be quite amazing. To enhance other drugs you really only need to take about 1/16-1/4 the amount needed to reach the 1st plateau.

Yeah! i agree with your enhanced version lol In fact I used similar combos in the past, with pregabalin instead of gabapentin. On most occasions, I got fucking clobbered lol.

I don't like DXM in hallucinogenic doses at all. Even threshold hallucinogenic doses (around 100 mg) make me feel uncomfortable. I do enjoy small doses (45-60 mg) in stimulating combos, but NEVER in relaxing mixes.

 

[weekend addiction]

Interesting about the mirtazepine.

tonight I took:
7.5mg of Remeron
200mg of Tagamet
6mg of Loperemide
.25 of klonopin (maintenence)
And a Tbsp of exceptionally strong bali kratom
2 shots of whiskey (seems to dissolve the kratom really well)
Smoked some dank too

Pupils are pinpoint and I'm nodding hard. not quite sweating like earlier but fucked up. Can't say the Remeron is hurting things. You would think I would be tired but all opiates give me mad insomnia. That seems like a lot of drugs and it is but I'm actually not very impaired. The alcohol seems to speed the breakdown of the kratom in my stomach. So maybe some more of that and I'll be out for the night.

 

[tentram]

No i dont.

When i wanna nod my titty tatas off i will inject copious amounts of morphine and eat the corresponding amount of oxycodone and valium needed while smoking weed. Hard liquor, although not a necessity, is sometimes added for satisfaction : garunteed.

Or your sobriety returned.

 

[dopemaster]

Longhauler I was only talking about drugs that are not opiates and make you nod. I could write a book about how much drugs I have done.

 

[Professer]

Cordalis Extract / crystal THP -- a few mg too many of the crystal THP stuff will put you into a twilight-sleep oblivion alone. Be careful...

I think it's something all of you should utilize in your 'non-opiate nod kits'.

" I knew a guy who played football in college and he would eat a whole pack of suda tablets before a game." -- gosh that sounds dangerous... stims + exercise in general.


Can you elaborate on melatonin dosages? Though what I've read about melatonin suppliments makes me want to stay away from them and not mess with the natural balance of things. I guess one time cant hurt.

 

[exists]

Can you elaborate on melatonin dosages?

Not much to say really... 1-2 mg should be enough, but everyone is different. I began taking 1/4-1/2 pills after realizing that too much melatonin was making it hard to remember my dreams. As with most drugs people tend to take too much, thinking more is better.

Though what I've read about melatonin suppliments makes me want to stay away from them and not mess with the natural balance of things. I guess one time cant hurt.

If you're worried, don't take it. Probably the best natural alternative is to switch over to red lights 1-2 hours before gong to bed. Blue lights (like our nice atmosphere) promote wakefulness; red lights help you sleep. Millions of years of evolution made it so

 

[LotusCR]

Actually, opioid induced constipation drugs and medications are very common. Be sure to know the side effects before using them, if not, then you might be in a world of trouble.

 

[PurpleKush1]

Ghb + Alcohol + Clonazepam knocked me on my ass. WHen i was able to smoke weed alcohol + xanax + weed was very euphoric whitout being too sedating

 

[Professer]

Not much to say really... 1-2 mg should be enough, but everyone is different. I began taking 1/4-1/2 pills after realizing that too much melatonin was making it hard to remember my dreams. As with most drugs people tend to take too much, thinking more is better.



If you're worried, don't take it. Probably the best natural alternative is to switch over to red lights 1-2 hours before gong to bed. Blue lights (like our nice atmosphere) promote wakefulness; red lights help you sleep. Millions of years of evolution made it so

It's not so much a worry. I just know what supplementing and playing with your natural balance of melatonin does which is not ideal for me personally. As I said though, one can't hurt. I still HIGHLY recommend a corydalis extract of some of those 98% pure crystal THP extracts to enhance any nodding combo out there. Even would really enhance an opioid nod. Could potentially take less and be able to still nod using corydalis. It's been used to treat addiction in china and stuff too. Has some interesting anti-addictive properties to it. I read a cool study about THP being a novel anti-addictive compound, wish I still had it on hand or a copy of it. It basically helped deal prevent mental aspects of certain 'triggers' to your addiction -- though the sedative properties alone have medicinal value for treating physical addiction.

 

[Specterchild]

Bupe(or bali Kratom) + Phenibut + L-Theanine + B1 + Hydroxizine + Clonidine + Alcohol(optional)

That will get me through an H craving. W/O Benzos or Strong opiates

 

[sub21lime]

I do have a script for Remeron.

Same here, like 10 years ago, I only took for a few weeks. I'm pretty sure I stopped taking em cuz they made me feel like a zombie. Idk it was a while back but anyways when I have no opiates I take benzos and smoke pot, if its night time I'll take some diph to kick the benzos in a lil more.

 

[AbusedTampon]

Love nodding, but almost always feel like an opiate is needed, not a strong one though. Anyways;

3g phenibut
90Mg codeine
150Mg DXM
10Mg valium
(klonopin or Xanax work equally as good)
Some non drowsy anti chlorogenic
A good G of Indica in a J or blunt

And any opiate works like kratom, hydro, oxy, Dilaudid etc. But a small line, 20-40Mg H, snorted works better than anything for me personally.