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Solvent 25i freebase form

Pill2Chill

Bluelight Crew
Joined
Apr 11, 2012
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5,517
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Belgium
Hi,

I have some 25i-nBOMe coming in soon, only problem is, I don't have an accurate scale so I will have to measure out doses by dissolving the 25i.
Now, I was wondering what a good, easy to get, and preferably cheap solvent would be. The 25i I'm getting is in its freebase form.

Thanks in advance.
 
You could use water, if you mix it with an acid - something like vinegar (acetic acid) could work if it's quite pure, look for white vinegar.
 
Thanks, useful stuff! Though I have no idea of how much vinegar I should add. I've read a few posts here and there saying a few drops is enough to turn a freebase into its salt form, but I've only read that about certain other drugs. I'd like to know specifically for 25i.

The amount I'm getting is 25mg. Howmuch h2o & howmuch vinegar would you guys suggest?

Input would greatly appreciated.
 
Do you have any perfume bottles or something similar? 1mg/1ml is a good start. And i'm not sure exactly how much acid to put in either - if you put a couple ml it should probably be fine.

Just note that when you do take it, avoid swallowing and hold it under your tongue for as long as possible. nbomes don't absorb too well through stomach, especially if they're base.
 
1mg per 1mL? WOW that's a lot of solvent. I'd recommend way less than that so dosing it doesn't require chugging anything, like 1mg per 1/10mL or 10cc's or even 5ccs.

.10 or .5 *********
 
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Yeah 1mg/ml does seem like alot. 20 units of solution per mg is probably how I'll do it. That should make dosing accurately easy, and it shouldn't be too much liquid to make taking it SL a pain. I'm aware of it being much less active orally than SL, so I'll definitely keep that in mind, thanks.

I'm gonna wait for some more detailed reply to the question on howmuch vinegar I should add because
if you put a couple ml it should probably be fine
is still a little too vague. =D

I was thinking of storing it in an little empty, glass bottle that used to contain pills. I've been using one of these to store my 2C-E and it seems like a good choice to me.
 
You could use water, if you mix it with an acid - something like vinegar (acetic acid) could work if it's quite pure, look for white vinegar.
you are thinking about applying it sublingually later on, correct? but isn't the best way to ingest the NBOMe compounds nasally? and I wouldn't want to put vinegar into my nose...
 
you are thinking about applying it sublingually later on, correct? but isn't the best way to ingest the NBOMe compounds nasally? and I wouldn't want to put vinegar into my nose...

There's a way to complex NBOMe base using some sugar (I can't remember what it is off the top of my head, check the megathread) which can also help it penetrate membranes. I don't really know anything about doing it nasally though, never tried it that way.
 
Thanks for all the replies!

I'm not really that interested in smoking or snorting it. Sublingual dosing is what I'd prefer to do.

The 25i has arrived since I started this topic. I'd very much like to get this stuff into a solution, but I'm still not very sure what would be best. The 25i will be stored for quite some time as I don't expect to go through 25mg that fast. I doubt I'm the first one to run into this problem, so I'm thinking there has to be an easy solution I just don't know about. I just hope someone here does know. ;)
 
Sublingual dosing is very hit or miss with this compound unless it is complexed and put on a blotter to "contain" it under your tongue. I don't personally have experience with it but lots of people do and I read the megathreads on 25i before I determined that I will dose nasally just to ensure that I actually get the dose properly in a controlled fashion.

Using a solution of watered down vodka will preserve the drug itself, and will allow you the most accurate dosing.

Complexing requires more than "sugar", but what is known as HPBCD or cyclodextrin, which is basically a ring of sugar which increases the bioavailability.. but its just another step to making things more complex, and its hard to come by and seems wholly uncessary unless you absolutely cannot live with snorting anything.

Ive yet to try it (likely will this weekend) but I did do tests to see what volume of liquid my nose could hold and honsetly I didnt even notice .1ml.. I plan to set up my solution so there is .5mg per .1ml. Using an insulin syringe with the cap chopped off so that the liquid can squirt out allows near exact dosing as well.. its the simplest and easiest way in my opinion
 
So, basically what you're saying is that I could use some random 35°+ vodka as a solvent? Would it dissolve easily? Would it be spread evenly throughout the solution?

Cheers, would be nice if this works, that would make things alot simpler. Is there anyone who could confirm this? Thanks. :)
 
Not sure how it works with alcohol, but the freebase doesn't really want to dissolve by itself so it's best to go the vinegar route. Also not sure about nasal bioavailability, but for the freebase to work sublingually you'll have to have HPBCD or beta-cylclodextrin. Using vinegar will turn it in to the acetate, so that means you'll not have to worry for any such things
 
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