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  • BDD Moderators: Keif’ Richards

Heroin, Morphine and Codeine questions

headshot101

Greenlighter
Joined
May 29, 2013
Messages
42
Hey there, I have to say I am a little lost :)

I am searching for the main differences between these three drugs: Heroin, Morphine and Codeine

From what I understand, they are all part of the Opiates family

I can't really make a difference between the effects - every time I find something like "warm and fuzzy feeling", is it true?

From the "high" would it possible to say:

Heroin > Morphine > Codeine

What about the (oral) doses?

Morphine (first time and no tolerance) would be around 10mg, +10mg increments if needed?

Codeine (first time and no tolerance) would be around 30mg, +30mg increments if needed?

What's about the actual duration of the effects of each of these drugs?

And more a general question: how quick does tolerance builds itself up?


Thank you :)
 
I can't anwser all these questions, I've only had experience with codeine syrup and I usually would drink 50ml which is 150mg for my bottle and I'd be buzzed for really long and that's without any tolerance, but I'd usually smoke weed with it and I'd feel warm and fuzzy for a few hours, tolerance probably does build fast but I'm not sure as I am not a very frequent user of the opiates
 
I can't anwser all these questions, I've only had experience with codeine syrup and I usually would drink 50ml which is 150mg for my bottle and I'd be buzzed for really long and that's without any tolerance, but I'd usually smoke weed with it and I'd feel warm and fuzzy for a few hours, tolerance probably does build fast but I'm not sure as I am not a very frequent user of the opiates

Thank you for your answer :D
Planned to get some codeine "only" - there is no difference if binded to something else like paracetamol (like I saw) or whatever but the price, right?
 
They're pretty much the same thing with much different potencies. Opiates last anywhere from 2-6 hours, depends on the individual, there are really no definitive answers. I find the codeine and heroin high to be more energetic than the morphine, which is seemingly more medicinal and sedating for me. I don't really care for morphine but I like codeine and i find Kratom to provide a better high than either, although Heroin is Heroin, i'm sure you can make some fairly accurate conclusions about that one.
 
Heroin is a broad term. Technically it's medicine but to my knowledge it converts to morphine at a certain stage in your body. Most conversion charts have morphine at 6 to 7 times stronger the codeine. I have been on morphine and would compare to hydrocodone. Since heroin is typically iv'd it's BA is a lot higher than oral morphine and probably significantly higher than iv morphine and astronomically higher than iv codeine. So heroin : junkies, morphine : moderate to severe pain, and codeine: mild to moderate pain (including cough)
 
both heroin and codeine are metabolized into morphine once taken, its all the same when u think about it. heroin is just a speedier high cuz its faster acting than morphine, and actually heroin is (D-morphine) its just a souped of version of morphine, where it reaches the BBB (blood brain barrier) faster than morphine, causing a more intense, smoother , speedier high, even though heroin is a pretty sedating high anyway, but to compare, i would say morphine is heavier..
 
I can't really make a difference between the effects - every time I find something like "warm and fuzzy feeling", is it true?

Yes - to some, the effects may seem indistinguishable, and to most they are fairly similar in nature, though different in intensity and ratios of particular effects, at least for me. Codeine is metabolized partly into morphine, but also apparently into codeine-6-glucuronide. Codeine in itself is believed to be inactive.
Morphine is active and highly potent in its own right, but is also metabolized into morphine-6-glucuronide which is also active and highly potent. The metabolism of codeine into C6G, morphine, and the morphine's subsequent metabolism into M6G explain much of the similarities in effects.
Heroin, or morphine diacetate/diacetylmorphine, is also inactive in itself, and quickly metabolized into morphine (from which to M6G) but as an intermediary metabolite it also produces 6-Monoacetylmorphine or 6-MAM (and 3-Monoacetylmorphine, which is either weakly or not active) which is a potent mu-opioid agonist. These metabolites, however, are only produced if the heroin is not taken orally - otherwise it is deacetylated in first-pass metabolism, and simply becomes morphine.

From the "high" would it possible to say:

Heroin > Morphine > Codeine

Absolutely. Heroin is more lipid-soluble than morphine, and when injected, smoked, plugged or insufflated, produces 6-MAM - this means it crosses the blood-brain barrier more quickly, so it gives a stronger rush - I also find that 6-MAM, though a short-lived intermediary metabolite, produces a more euphoric high than morphine.
Codeine is like morphine, but can never be as strong as a decent morphine nod for me (possibly because a certain dose of codeine depletes the enzyme responsible for its metabolism into active compounds), and at strong doses it is more itchy and nauseating than the other two.

Also, codeine should NEVER be injected, whereas heroin and morphine produce a massively euphoric rush when mainlined - but rather obviously, this is VERY dangerous and just about the archetype of decadent drug addiction.


What about the (oral) doses?
Morphine (first time and no tolerance) would be around 10mg, +10mg increments if needed?
Codeine (first time and no tolerance) would be around 30mg, +30mg increments if needed?

Heroin is impossible to gauge unless you have it in pharmaceutical form, or have access to test labs. Pure heroin is 1.5-2x more potent than morphine. Codeine is roughly 60-70% of the potency of oral morphine.

As a first-timer, I'd take 30-60mg of morphine orally, depending on your size; its bioavailability is low so only about 30% of that will make it into your brain, so maybe 10-20mg - should be a decent dose for a first-timer. Plugging and IV yield much higher BA, but are more risky, and I especially wouldn't recommend injecting.
As for codeine, I would take maybe 90-120mg.
On an empty stomach, I would wait 30-45 minutes before taking additional doses, but owing to the rather short duration of these drugs taking them in small increments orally may not yield satisfying results.

What's about the actual duration of the effects of each of these drugs?

Depends on how much you've taken, but generally I've found that codeine lasts 1-2 hours, followed by another 2 hours of residual sedation; heroin and morphine last around 4-6 hours for me, though oral ingestion always makes the effect a little longer than other ROAs.

And more a general question: how quick does tolerance builds itself up?

That depends on a huge amount of variables, but generally speaking: fast. With daily use you will be doubling your doses before you know it.
 
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