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drugs damage on the brain- summary

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hdth

Greenlighter
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Oct 20, 2012
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So this is a thread of various drugs and their damaging effects on the brain, specifically physical damage because some drugs can worsen or bring up mental problems. Oviously there is information out there to research all this yourself, but this is just a short summary.

Opiates- Opiates are really actually a safe drug when looking at the brain damage. They make your brain less responsive to natural endorphin's which are released during pain or in some cases remarkable life events. Their also very addictive which is why people tend to avoid them all together.

Cocaine- Cocaine effects the dopamine receptors. Damage can occur to the dopamine receptors making them useless making the user depressed. Also addictive.

Meth- Possibly the worst substance you can put up to your brain. Stimulates the production of dopamine 10X the normal amount. Long term users feel very depressed without the drug hence it is also addictive. Brain damage is reversible with lots of time.

MDMA/ecstasy- The most overlooked drug considering the brain. The MA in MDMA stands for methylamphetamine or meth. The MD in MDMA stands for methylenedioxy which effects the serotonin receptors shortening the dendrites. Possibly worse for your brain than meth it causes depression and a large decrease of function in the thalamus and hypothalamus.

Weed- pretty much harmless, brains become less responsive to natural cannabinoids for a short period of time.

Alcohol- swells the brain causing brain damage but not anything major.

Shrooms- Also quite harmless.

LSD- Harmless BUT, can change your personality if you take high doses. Some people just never stop tripping.

Benzos- Some debate and research showing it can damage the cerebral cortex from long term use. Worst withdrawl symptoms when addictive.

Ketamine- Can change your personality but otherwise fairly harmless.

DMT- Naturally made and metabolized in our brains so no brain damage.
 
Serious drainbramage from most drugs i have dried but its ok it gonna gro back eventually.
 
hdth said:
Alcohol- swells the brain causing brain damage but not anything major.
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alcohol actually is pretty bad for the brain. Long term use "shrinks" the brain volume, and causes issues with deficiencies in a number of vitamins and processes.
 
Where did you get this information from?

Looks like you pulled it out of your ass. Am I right?

You seem to be confusing tolerance with neurotoxicity - a lot.
 
See we always get complacent when it comes to our health. We always decieve ourselves and say, Wulp it will grow back and I haven't done that much damage so I'll be okay. Listen I have been thru a 7 month meth induced psychosis where I was for sure thought I was going to get eaten up. In jail thinking cannibals and zombies where after me and it was like I was living the past, present, and future. Scary stuff don't decieve yourself....Opiates are bad for the brain when taken to mu because no oxygen to the brain.
 
Readers, the OP's original post is prototypical of the mix of information and misinformation in media which has convinced the masses that individual drugs are more or less safe than they usually are.
 
Every drug group listed there basically will cause the user to be depressed over time, especially if the user is on multiple drugs from the groups, do not live in ignorance guys, none of these drugs are 'safe'. They are only safe to the ones who know what they are doing. Keep in mind also that these drugs change our brain chemistry so they all damage our brains over time
 
No...every drug listed has potential to rapidly improve depression

Who knows what they're doing?

I change my brain chemistry by eating lunch
 
^ I don't know what you're on about, seems like since you started taking your scripts your extremely pro drug..

Yea the drugs can potentially rapidly improve depression, WHILE you are on them. Getting off them will no doubt cause some problems which eventually clear up.
 
^ I saw nothing pro drug about hochiminh's posts here... what does 'taking your scripts' mean? I found his remark about all the drugs improving depression amusing, I think you didn't notice his sarcasm. All euphoriants "rapidly abate depression" heeeheee

As for the OP, I would have given him a B+ on his 10th grade Biology assignment
 
F1n1shed said:
^ I don't know what you're on about, seems like since you started taking your scripts your extremely pro drug..

Yea the drugs can potentially rapidly improve depression, WHILE you are on them. Getting off them will no doubt cause some problems which eventually clear up.
Click to expand...

I've been taking medication for well over a year. I'm pro science; I can elaborate if you want; I've done the research. Try me :).

Who says I have to get off my medicine?

blakmike said:
^ I saw nothing pro drug about hochiminh's posts here... what does 'taking your scripts' mean? I found his remark about all the drugs improving depression amusing, I think you didn't notice his sarcasm. All euphoriants "rapidly abate depression" heeeheee

As for the OP, I would have given him a B+ on his 10th grade Biology assignment
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;)

But seriously I could make a case for all drugs the op listed as treatments for depression, not just based on recreational potential/escalating doses. In fact every psychoactive drug has potential to alleviate depression.
 
they say heroin is the safest drug (besides risk of overdose and physical dependency) opiates are very benine, and cause the least amount of problems in ur system, now using needles and snorting heroin, thats totally different because using needles period is bad for ur body, and ur nasal cavity..
 
Ho-Chi-Minh said:
I've been taking medication for well over a year. I'm pro science; I can elaborate if you want; I've done the research. Try me :).

Who says I have to get off my medicine?



;)

But seriously I could make a case for all drugs the op listed as treatments for depression, not just based on recreational potential/escalating doses. In fact every psychoactive drug has potential to alleviate depression.
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Well if you stay on the scripts i understand how they can help depression. Just pointing out that they aren't a long term cure or fix, well they are if you stay on them as you were saying. And i know you've done your research don't worry heh.
 
F1n1shed said:
^ I don't know what you're on about, seems like since you started taking your scripts your extremely pro drug..

Yea the drugs can potentially rapidly improve depression, WHILE you are on them. Getting off them will no doubt cause some problems which eventually clear up.
Click to expand...

Why wouldn’t he be? If something made your outlook on life better, wouldn’t you have a positive bias toward it?
 
Whoa whoa whoa...OP has a lot of inaccuracies (sorry)

I applaud the effort OP but the information you provide is oversimplified at best and just plain false at worst. I might revisit this thread when I have some time to clarify some of the OP info to be more accurate if you all are ok with that and think someone should. I mean, I'm sure there's a million threads about the same thing.

Just two things for now though:

1) The truth is that we really have very little knowledge of the actual mechanisms by which these drugs work or long term effects of prolonged use because, well, letting us neuroscientists experiment on humans is generally frowned upon. We really are still in the Dark Ages in this regard.

2) Too much of anything is generally bad. You can't claim that DMT doesn't cause brain damage based only on the argument that since it's produced by our brains naturally, it can't possibly damage it. WRONG. Our bodies are 70% water and yet it is possible to OD on water (PSA: it's called hyponatremia and is commonly associated with MDMA use - Stay hydrated while you're rolling, kids, but guzzling too much water can be just as bad).

We all have a shitload to learn about how these things work and what the dangers are. I hope I didn't come off too snarky 8) I just wanted make sure we're disseminating the most accurate facts we have so far.
 
The value of this thread has been established, as can be seen. Feel free to voice your knowledge.

If I may: we have yet to prove that DMT exists as an endogenous cranial compound.

While there are limits to learning the precise actions of all drugs, factors such as molecular complexity and legality has confounded or limited current scientific knowledge of several, whilst we can pretty definitively elaborate on the mechanisms of others.
 
I gotta say, a lot of this is bullshit.

You really need to do some research before you post about something as serious as the dangers of drugs. Alcohol is extremely dangerous, and Weed has a high likeability to induce psychotic illnesses such as Schizophrenia.
 
red_bandit said:
I applaud the effort OP but the information you provide is oversimplified at best and just plain false at worst. I might revisit this thread when I have some time to clarify some of the OP info to be more accurate if you all are ok with that and think someone should. I mean, I'm sure there's a million threads about the same thing.

Just two things for now though:

1) The truth is that we really have very little knowledge of the actual mechanisms by which these drugs work or long term effects of prolonged use because, well, letting us neuroscientists experiment on humans is generally frowned upon. We really are still in the Dark Ages in this regard.

2) Too much of anything is generally bad. You can't claim that DMT doesn't cause brain damage based only on the argument that since it's produced by our brains naturally, it can't possibly damage it. WRONG. Our bodies are 70% water and yet it is possible to OD on water (PSA: it's called hyponatremia and is commonly associated with MDMA use - Stay hydrated while you're rolling, kids, but guzzling too much water can be just as bad).

We all have a shitload to learn about how these things work and what the dangers are. I hope I didn't come off too snarky 8) I just wanted make sure we're disseminating the most accurate facts we have so far.
Click to expand...

I agree with you, especially on the DMT part. I know it is an amazing chemical but people give it too much credit. Just because something is naturally occurring in our brain, doesn't mean you can use chemicals to make your brain pour that neuro transmitter out in an unnatural way. I mean using DMT on a semi regular basis must cause some noticeable alterations in the brain.

The part i agree with OP on is MDMA. There are too many ravers who think, o i have pure MDMA it is practically harmless. And they frown up on someone using meth as if it is causing 10x as much damage. WRONG, MDMA in my experience is the more detrimental chemical to the brain. I noticed recovery from meth at insanely fast rates, even pulling all nighters. MDMA how ever... was a slow dragging process with many long term effects. Out of the main stream drugs we know about (not the thousands of weird RC's) i would rate MDMA as the most brain damaging chemical. There really isn't anything that can cause so many abnormalities in your brain as fast as MDMA. I noticed huge issues with my self after that first night of dosing it.
 
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